• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.1
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• pp.174-182
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• 2007

In this paper, we study the influence of infection ratio on gradual reduction of drug dose for the five state HIV infection model that explicitly includes the population of the virus. We first compute all equilibrium points of the model and investigate the stabilities of them. As a result, a bifurcation diagram is obtained which shows a change in the equilibrium points, or in their stability properties, as the drug effect $\eta$ is varied from 0 to 1(alternatively, drug dose is changed from 1 to 0). Based on the bifurcation diagram, we show that the gradual reduction of drug dose can be applied for the treatment of AIDS patients. Moreover, we analyze the influence of the variation of infection ratio on the gradual reduction treatment. Computer simulation results are also presented to validate the proposed results.

• Journal of Institute of Control, Robotics and Systems
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• v.10 no.12
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• pp.1148-1154
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• 2004

The goal of this paper is to verity that the gradual reduction of drug dose (GRDD), which has already been shown by authors to be effective for a simplified HIV infection model, still works for a more realistic model. While the simplified HIV infection model does not take into account an helper-independent CTL, the five state nonlinear model proposed by Wodarz describes the dynamics of both helper-dependent and helper-independent CTL in HIV infection. In this paper, it is shown that, by applying GRDD to Wodarz's five state HIV infection model, the state of HIV infected patient converges to that of non-progressor whose immune response is excited so that his symptom would not be developed into AIDS. Roughly speaking, GRDD is 'slow reduction of dose after the maximum dose for a certain period.' It turns out that an equilibrium representing non-progressor is locally asymptotically stable for the most values of drug dosage, which is required to hold in order to apply GRDD. Simulation results establish that GRDD is still considerably effective both for an AIDS patient and a patient who has been on HAART for a long time.

• Journal of the korean academy of Pediatric Dentistry
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• v.31 no.1
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• pp.46-51
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• 2004

Talon cusp is cusp-like structure that develops additionally in crown of anterior tooth. And it is one of dental anomalies. Talon cusp can cause various diagnostic, functional, aesthetic problems depending on the size and configuration of cusp. there is a tendency for caries to occur in the developmental grooves, and advanced attrition, periodontal problems, irritation the tongue and temporomandibular pain, occlusal interference and displacement of affected tooth may result. Therefore, early diagnosis and appropriate treatment of each case is important so that it minimize local problems, such as caries, periodontal diseases, and malocclusion. These cases which are in permanent and primary anterior teeth are about gradual reduction forming reparative dentine and complete reduction of talon cusp and root canal therapy which is an alternative and effective form of treatment when gradual reduction of talon cusp may not be possible.

• The KIPS Transactions:PartA
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• v.9A no.3
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• pp.379-386
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• 2002

This paper presents a scheduling approach for synthesizing pipelined datapaths under resource constraints. Our approach builds up a schedule based on gradual mobility reduction in contrast to other algorithms of previous researches, where an operation being scheduled is selected by using a priority function. The proposed method consists of a scheduling algorithm and a decision algorithm for detecting any violation against resource constraints. Our approach evaluates whether or not a scheduling solution can exist in case an operation temporarily is assigned to the earliest or latest control step among the assignable steps for the operation. If a solution cannot be found, it is impossible to assign the operation to that step due to a violation against resource constraints, and so we can eliminate that control step. This process is iterated until a reduction of mobility for all operations can not be obtained. Experiments on benchmarks show that this approach gains a considerable improvement over those by previous approaches.

• Journal of Broadcast Engineering
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• v.18 no.5
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• pp.738-748
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• 2013

The present study investigated whether convergence training in which has an effect on reducing visual discomfort in viewing 3D TV. The stereoscopic depth of 3D training stimulus was gradually increased while maintaining individual visual discomfort at a minimum value. Participants were randomly assigned into one of three groups: a control group and two training groups. For both training groups, all procedure and the disparity range of training stimuli were the same except the order of the disparities of training stimuli. One of the two different training procedure was provided: gradual change or random change of the disparities of training stimulus. Training itself was very effective so that convergence fusional range was improved after three sessions of training with intervals of two weeks. In order to evaluate the effect of convergence training on visual discomfort, the subjective visual discomfort in 3D TV viewing was measured before and after training sessions using questionnaire. The results showed that a significant reduction in visual discomfort was found after training only in the group of gradual change. These results demonstrated a repeated convergence training might be helpful in reducing the visual discomfort in 3D TV environment.

• Magazine of the Korean Society of Agricultural Engineers
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• v.44 no.1
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• pp.142-154
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• 2002

This study was performed to investigate constraint effects of deformation (heaving, lateral displacement) of clayey foundation reinforced with sheet pile at the tip of banking on soft ground, under intact state (natural) and the state of vertical drain respectively. The following results are obtained. 1. In view of reduction in heaving or lateral displacement, sheet pile is not supposed to be of use. 2. Sheet pile is effective only when vertical drain is installed for acceleration of consolidation and gradual loading is applied.

• Bulletin of the Korean Chemical Society
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• v.20 no.11
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• pp.1340-1344
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• 1999

The electrochemical behavior of oxide layers on aluminium was studied using electrochemical impedance spectroscopy. Impedance spectra were taken at a compact and a porous oxide layer of Al. The anodic films on Al have a variable stoichiometry with gradual reduction of oxygen deficiency towards the oxide-electrolyte interface. Thus, the interpretation of impedance spectra for oxide layers is complicated, with the impedance of surface layers differing from those of ideal capacitors. This layer behavior with conductance gradients was caused by an inhomogeneous dielectric. The frequency response cannot be described by a single RC element. The oxide layers of Al are properly described by the Young model of dielectric constant with a vertical decay of conductivity.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.19 no.4 s.74
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• pp.347-356
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• 2006

In this paper, practical nonlinear inelastic analysis method of 3-dimensional steel structures accounting for gradual yielding with fibers on a section is developed. Geometric nonlinearities of member(p-$\delta$) and frame(p-$\Delta$) are accounted for by using stability functions. Residual stresses are considered by assigning initial stresses to the fiber on the section. The elastic core in a section is investigated at every loading step to determine the axial and bending stiffness reduction. The strain reversal effect is captured by investigating the stress change of each fiber. The proposed analysis proves to be useful in applying for practical analysis and design of three-dimensional steel frames.

• Design & Manufacturing
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• v.15 no.4
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• pp.51-56
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• 2021

Piercing is the process of shearing a circular hole in sheet metal, whose high shear force makes it difficult to secure the durability of tools. In addition, uneven clearance between tools due to poor alignment of the piercing punch causes accelerated die wear and breakage of the tool. This study reviewed the feasibility of in-situ determining alignment failure during the piercing process by analyzing the signal deviation of a bolt-type piezo sensor installed inside the tool whose alignment level was controlled. Finite element analysis was performed to select the optimal sensor location on the piercing tool for sensitive detection of process signals. A well-aligned piercing process results in uniform deformation in the circumferential direction, and shearing is completed at a stroke similar to the sheet thickness. Afterward, a sharp decrease in shear load is observed. The misaligned piecing punch leads to a gradual decrease in the load after the maximum shear load. This gradual decrease is due to the progressive shear deformation that proceeds in the circumferential direction after the initial crack occurs at the narrow clearance site. Therefore, analyzing the stroke at which the maximum shear load occurs and the load reduction rate after that could detect the misalignment of the piercing punch in real-time.

• Restorative Dentistry and Endodontics
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• v.18 no.2
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• pp.463-468
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• 1993

The purpose of this study was to evaluate the effects of Vitapex on the periapical lesions. Thirteen single-rooted teeth from ten patients who visited the SNU hospital were endodontically treated with Vitapex and Gutta percha cone, and radiographically and clinically evaluated for a period of 1 to 6 months. The results were as follows : 1. The loss of clinical symtoms was observed in all 13 teeth. 2. The reduction of size of periapical lesions in radiographs was observed in 10 teeth. The periapical lesions of remaining 3 teeth also look better in the radiographs. 3. All 13 teeth showed the reduction of radiolucency. 4. The gradual resorption of Vitapex over the root apex was observed.