• 제목/요약/키워드: gradual aging

검색결과 66건 처리시간 0.03초

노령견의 생리적 변화에 따른 필요 영양소 및 질병에 관한 연구 (The Physiologic change associated with aging, essential nutrients and their diseases in senior or geriatric dogs)

  • 정형학
    • 한국응용과학기술학회지
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    • 제35권4호
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    • pp.1456-1471
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    • 2018
  • 이 논문은 노령견이 필요한 영양을 다루며, 노령견이 필요로 하는 영양평가를 검토하고, 노령화와 관련하여 흔히 발생할 수 있는 영양의 문제점들을 등을 제시하고자 한다. 즉, 이연구의 목표는 노령견의 노령화와 관련된 생리적인 변화, 필수영양소 및 그와 관련된 질병을 탐구하는데 있다. 2002년의 조사에 의하면, 미국에서 기르는 반려견의 30%-40%는 나이가 7세이상이라고 한다. 유렵의 경우 1983년과 1995년을 비교했을 때 나이가 7세이상의 반려견의 수는 약 50% 늘었다고 한다. 2012에 미국에서 실시한 이메일 조사에 의하면, 50,347명의 응답자 중에서 33.2%가 6살-10살의 노령견을 기르고 있으며, 11살이상의 노령견을 기르는 응답자는 14.7%라고 한다. 가정에서 기르는 반려견의 평균수명은 건강관리, 노령화 및 영양에 영향을 받는다. 그리고 견종, 유전, 영양, 환경 등의 요소에 따라서 노령화의 정도가 다르다. 10살이 넘은 많은 반려견들이 활력이 넘치고 건강하다고 할지라도, 대부분의 반려견들은 5세-6세가 되면, 노령화와 관련된 징조를 보이기 시작한다. 여러가지 질병을 치유할 수 있는 의학의 발달과 영양의 발달로 인하여, 반려견의 평균수명은 점점 증가하고 있다. '노령견을 위한 영양의 목표'는 노령견이 건강하고 활력 넘치게 하며, 노령과 관련된 건강상의 문제가 늦게 시작되고, 노령화를 지연시키며, 삶의 질을 향상시키며, 기대수명을 늘리는데 있다. 노령화는 생리적인 변화를 가져온다. 우리가 육안으로 명백하게 느낄 수 있는 변화들은 털의 색깔이 하얗게 변하는 것, 몸의 기력이 떨어는 것, 시각이나 청각 등의 감각기관에 문제가 오는 것 등이 있으며, 표면적으로 느끼기 어려운 변화들은 소화관, 면역시스템, 신장 등 장기와 관련된 생리적인 변화들이다. 반려견이 필요로 하는 영양은 나이에 따라서 다르다. 또한 노령화가 진행됨에 따라서 발생할 수 있는 영양과 관련된 많은 질병들이 있으며, 이러한 질병에는 영양이 매우 중요하다.

시편의 열화에 따른 가스터빈 로터볼트 기계적 강도평가 (Evaluation for mechanical hardness of gas turbine rotor bolt according to deterioration of specimen)

  • 길두송;안연식;박상기
    • 동력기계공학회지
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    • 제15권4호
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    • pp.19-24
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    • 2011
  • The operational efficiency of domestic gas turbine is about 25% and it is now in the trend of the gradual growth in spite of the severe temperature, frequent starting and shutdown according to the environmental management and the energy-efficient use. Rotor bolts of gas turbine in power plants have been the cause of defects because these gas turbines have been operated for a long time under the high pressure and temperature environment experiencing the aging change and stress concentration of the bonded part. The connection parts of the bolt revealed various failure shape and these parts were elongated under very low pressure when operated in the relaxed condition. The cause is in the lack of the metal distribution in the bottle lack area and the cap screw of the bolt is broken totally in case that the nut is fastened in most cases. Gas turbine rotor bolts are connected to the rotor wheel and these bolts caused the vibration, the bulk accident of the rotor in the event that the coupling power among these bolts was relaxed. Therefore, we would like to evaluate the soundness of the main part of the gas turbine rotor bolt through the measurement of the inner condition change along with the mechanic deterioration and temperature, stress in the gas turbine rotor material.

Variation in Solar Limb Darkening Coefficient Estimated from Solar Images Taken by SOHO and SDO

  • Moon, Byeongha;Jeong, Dong-Gwon;Oh, Suyeon;Sohn, Jongdae
    • Journal of Astronomy and Space Sciences
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    • 제34권2호
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    • pp.99-103
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    • 2017
  • The sun is not equally bright over the whole sphere, but rather is darkened toward the limb. This effect is well-known as limb darkening. The limb darkening coefficient is defined by the ratio of the center intensity to limb intensity. In this study, we calculate the limb darkening coefficient using the photospheric intensity estimated from solar images taken by solar and helispheric observatory (SOHO) and solar dynamics observatory (SDO). The photospheric intensity data cover almost two solar cycles from May 1996 to December 2016. The limb darkening coefficient for a size of 0.9 diameter is about 0.69 and this value is consistent with solar limb darkening. The limb darkening coefficient estimated from SOHO shows a temporal increase at solar maximum and a gradual increase since the solar minimum of 2008. The limb darkening coefficient estimated from SDO shows a constant value of about 0.65 and a decreasing trend since 2014. The increase in the coefficient reflects the effect of weakened solar activity. However, the decrease since 2014 is caused by the aging effect.

Study on the Self-Aligned HgTe Nanocrystallites Induced by Controlled Precipitation Technique in HgTe-PbTe Quasi-Binary Semiconductor System: Part I. TEM Study

  • Lee, Man-Jong
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2002년도 하계학술대회 논문집
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    • pp.226-231
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    • 2002
  • The present study discusses the results of the controlled precipitation of HgTe nanocrystals in a PbTe semiconductor matrix and demonstrates its effectiveness in producing well-organized and crystallographically aligned semiconductor nanocrystals. Following the similar procedure used in metallic alloys, the semiconductor alloys are treated at 600$^{\circ}C$ for 48 hours, quenched and aged up to 500 hours at 300$^{\circ}C$ and 450$^{\circ}C$ to induce homogeneous nucleation and growth of HgTe nanocrystalline precipitates. Examination of the resulting precipitates using transmission electron microscopy (TEM) and high resolution TEM (HRTEM) reveals that the coherent HgTe precipitates form as thin discs along the {100} habit planes making a crystallographic relation of {100}$\sub$HgTe///{100}$\sub$PbTe/ and [100]$\sub$HgTe///[100]$\sub$PbTe/. It is also found that the nato-disc undergoes a gradual thickening and a faceting under isothermal aging up to 500 hours without any noticeable coarsening. These results, combined with the extreme dimension of the precipitates (4 nm in length and sub-nanometer in thickness) and the simplicity of the formation process, leads to the conclusion that controlled precipitation is an effective method for the preparation of the desirable quantum-dot nanostructures.

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신장 기능과 틸로미어 (Kidneys with bad ends)

  • 서동철
    • Childhood Kidney Diseases
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    • 제12권1호
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    • pp.11-22
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    • 2008
  • Telomeres consist of tandem guanine-thymine(G-T) repeats in most eukaryotic chromosomes. Human telomeres are predominantly linear, double stranded DNA as they ended in 30-200 nucleotides(bases,b) 3'-overhangs. In DNA replication, removal of the terminal RNA primer from the lagging strand results in a 3'-overhang of uncopied DNA. This is because of bidirectional DNA replication and specificity of unidirectional DNA polymerase. After the replication, parental and daughter DNA strands have unequal lengths due to a combination of the end-replication problem and end-processing events. The gradual chromosome shortening is observed in most somatic cells and eventually leads to cellular senescence. Telomere shortening could be a molecular clock that signals the replicative senescence. The shortening of telomeric ends of human chromosomes, leading to sudden growth arrest, triggers DNA instability as biological switches. In addition, telomere dysfunction may cause chronic allograft nephropathy or kidney cancers. The renal cell carcinoma(RCC) in women may be less aggressive and have less genomic instability than in man. Younger patients with telomere dysfunction are at a higher risk for RCC than older patients. Thus, telomeres maintain the integrity of the genome and are involved in cellular aging and cancer. By studying the telomeric DNA, we may characterize the genetic determinants in diseases and discover the tools in molecular medicine.

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Distribution of the serum Ig G titers to whole cell and leukotoxin of Mannheimia haemolytica Al in Holstein and Korean indigenous cattle slaughtered in abattoir

  • Byun, Jae-Won;Kim, Kyung-Ho;Lee, Sung-Mo;Lee, Jung-In;Hwang, Hyun-Soon;Kim, Yong-Hee
    • 한국동물위생학회지
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    • 제26권4호
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    • pp.323-328
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    • 2003
  • A total of 419 slaughtered cattle were used to investigate the serum Ig G titers to the Mannheimia haemolytica Al whole cell and leukotoxin recognized with important virulence factor in bacterial pathogenesis. Data obtained in this study were represented with average absorbance${\pm}$standard deviation. Serum Ig G titers were detected with the ranges from 0.1 to 0.5 at 490nm. Whole cell titers were higher than leukotoxin antibody on the whole. Antibody titers of slaughtered cattle between races, ages have no significant difference but gradual decrease under aging in dairy cow for whole cell (decline mean titer from 0.29 to 0.27 according to age) was undertaken. Holstein bulls shipped from Seoul province had a significantly lower Ig G titers than those from another ones (p<0.05).

농촌지역 보건지소 건축의 특성에 관한 연구 - 익산시 보건소 관할 지소를 중심으로 - (A Study on the Architectural Characteristics of the Health Care Center Branch in Rural Area Ik-san city)

  • 이동숙;김은영;윤충열
    • 한국농촌건축학회논문집
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    • 제19권4호
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    • pp.9-16
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    • 2017
  • There are an increasing number of healthcare facilaties, especially branch offices, in rural areas to serve the aging population living there. However, there has been a gradual decline in the ratios of recognition, satisfaction and utilization by people who live in the regions. A significant reason of declining the ratios should be the population decline, but the most of population hierarchy shows the groups of elderly people over 60. This result appears to be limited to visit the public health centers. According to the result of population hierarchy, a branch office of public health center has been re-established as a complex welfare facility which can be fulfilled in the functions of basic medical supports and cultural supports. This research is focused on collecting the meaningful information of the status of physical facilities and utilization with 15branch offices of public health care centers in the rural regions near the city of Ik-San city. In addition, this research has a purpose of getting fundamental data for future architectural plans of the branch offices in rural regions with the results about the status of facility operation systems and users' needs.

Electron Microscope Analyses of Self-aligned HgTe Nanocrystallites Induced by Controlled Precipitation Technique

  • Lee, Man-Jong
    • Transactions on Electrical and Electronic Materials
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    • 제3권3호
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    • pp.8-13
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    • 2002
  • Controlled precipitation of quasi-binary semiconductor system is newly proposed as an effective and reliable technique for the formation of well-defined and crystallographically aligned semiconductor nanostructures. Using HgTe-PbTe quasi-binary semiconductor system, self-aligned HgTe nanocrystallites distributed three dimensionally within PbTe matrix were successfully formed by the simple three step heat treatment process routinely found in age hardening process of metallic alloys. Examination of the resulting nano precipitates using conventional transmission electron microscopy (CTEM) and high resolution TEM (HRTEM) reveals that the coherent HgTe precipitates form as thin discs along the (100) habit planes making a crystallographic relation of {100}$\_$HgTe///{100}$\_$PbTe/ and [100]$\_$HgTe///[100]$\_$PbTe/. It is also found that the precipitate undergoes a gradual thickening and a faceting under isothermal aging up to 500 hours without any noticeable coarsening. These results, combined with the extreme dimension of the precipitates (4-5 nm in length and sub-nanometer in thickness) and the simplicity of the formation process, leads to the conclusion that controlled precipitation is an effective method for preparing desirable quantum-dot nanostructures.

건강보험수가제도 개선을 통한 의료전달체계 확립방안 (Establishment of Healthcare Delivery System through Improvement of Health Insurance System)

  • 오영호
    • 보건행정학회지
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    • 제29권3호
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    • pp.248-261
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    • 2019
  • Establishing a healthcare delivery system is key to building a cost-effective healthcare system that can prevent the waste of healthcare resources and increase efficiency. Recently, the rapid increase in the national medical expenditures due to the aging of the population and the increase in chronic diseases has raised the question about the sustainability of the healthcare system including the health insurance system. This is why we need to reform the medical delivery system, including the function setting of medical institutions. Accordingly, gradual and practical efforts based on the recognition of reality are needed for solving the problems and improving the medical delivery system. The first effort is to secure policy measures to establish functions and roles of medical institutions which are the basis of the healthcare delivery system, and a systematic medical use system for appropriate medical use. This approach can be achieved through a reasonable health insurance schemes. Without reasonable reform efforts, it will be difficult for Korea's health care system to develop into a system that can provide cost-effective and high-quality medical services that the people want.

장애인을 위한 스마트 모빌리티 시스템 개발 (Development of Smart Mobility System for Persons with Disabilities)

  • 유영준;박세은;안태준;양지호;이명규;이철희
    • 드라이브 ㆍ 컨트롤
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    • 제19권4호
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    • pp.97-103
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    • 2022
  • Low fertility rates and increased life expectancy further exacerbate the process of an aging society. This is also reflected in the gradual increase in the proportion of vulnerable groups in the social population. The demand for improved mobility among vulnerable groups such as the elderly or the disabled has greatly driven the growth of the electric-assisted mobility device market. However, such mobile devices generally require a certain operating capability, which limits the range of vulnerable groups who can use the device and increases the cost of learning. Therefore, autonomous driving technology needs to be introduced to make mobility easier for a wider range of vulnerable groups to meet their needs of work and leisure in different environments. This study uses mini PC Odyssey, Velodyne Lidar VLP-16, electronic device and Linux-based ROS program to realize the functions of working environment recognition, simultaneous localization, map generation and navigation of electric powered mobile devices for vulnerable groups. This autonomous driving mobility device is expected to be of great help to the vulnerable who lack the immediate response in dangerous situations.