• Journal of Korean Neurosurgical Society
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• 제66권4호
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• pp.465-475
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• 2023

Objective : Our objective is to analyze the occurrence, clinical course and risk factors for glioma patients with leptomeningeal metastasis (LM) according to different metastasis patterns and clinical variables. Methods : We retrospectively reviewed data from 376 World Health Organization (WHO) grade II-IV adult glioma patients who were treated in the National Cancer Center from 2001 to 2020. Patients who underwent surgery at other institutions, those without initial images or those with pathologically unconfirmed cases were excluded. LM was diagnosed based on magnetic resonance imaging (MRI) findings or cerebrospinal fluid (CSF) cytology. The metastasis pattern was categorized as nodular or linear according to the enhancement pattern. Tumor proximity to the CSF space was classified as involved or separated, whereas location of the tumor was dichotomized as midline, for tumors residing in the thalamus, basal ganglia and brainstem, or lateral, for tumors residing in the cerebral and cerebellar hemispheres. Results : A total of 138 patients were enrolled in the study. A total of 44 patients (38%) were diagnosed with LM during a median follow-up of 9 months (range, 0-60). Among the clinical variables, tumor proximity to CSF space, the location of the tumor and the WHO grade were significant factors for LM development in univariate analysis. In multivariate analysis, the midline location of the tumor and WHO grade IV gliomas were the most significant factor for LM development. The hazard ratio was 2.624 for midline located gliomas (95% confidence interval [CI], 1.384-4.974; p=0.003) and 3.008 for WHO grade IV gliomas (95% CI, 1.379-6.561; p=0.006). Conclusion : Midline location and histological grading are an important factor for LM in glioma patients. The proximity to the CSF circulation pathway is also an important factor for WHO grade IV glioma LM. Patients carrying high risks should be followed up more thoroughly.

• 대한한방내과학회지
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• 제44권3호
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• pp.285-293
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• 2023

Background: Irritable bowel syndrome (IBS) is a digestive disorder characterized by abdominal discomfort or pain accompanied by a change in stool condition. Owing to its complicated mechanisms, a standard treatment for IBS has not yet been established. Yukgunja-tang (YGT) is a Korean herbal medicine known in Asia to be effective in the treatment of gastrointestinal symptoms. In this study, we will conduct a systematic review of randomized controlled trials (RCTs) to assess the efficacy and safety of YGT in IBS treatment. Methods and analysis: English databases, such as Embase, Medline (via PubMed), Allied and Complementary Medicine Database, and Cochrane Central Register of Controlled Trials, will be searched for articles published up to April 2023. Additional databases, such as five Korean, one Chinese, and one Japanese database, will be included. RCTs and quasi-RCTs will also be included in the assessment of the efficacy of YGT. The overall efficacy rate will be the primary outcome, and data such as IBS quality-of-life measurements, global symptom scores, and adverse events will be the secondary outcomes. Review Manager Version 5.3 will be used for evaluation, and the risk of bias (RoB) will be evaluated using Cochrane Collaboration's RoB tool. The Grading of Recommendations Assessment, Development, and Evaluation approach will be used to score the quality of evidence. Conclusion: This study will demonstrate the efficacy and safety of YGT for treating patients with IBS.

• 대한안전경영과학회지
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• 제25권4호
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• pp.57-65
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• 2023

The public safety management guidelines were introduced in 2019 and continue to be dedicated to advancing comprehensive measures for public safety management, with a primary focus on prioritizing the safety and well-being of the public within governmental institutions. To achieve this goal, our previous study developed a establishment procedure of risk assessment-based safety inspection system for public institutions that order construction projects and applied it to highway construction projects to evaluate its effectiveness. To enhance the practicality of the establishment procedure, it is essential to collect and analyze feedback from stakeholders regarding its performance and suitability. This study conducted a survey involving 200 participants who had experience with the establishment procedure, and performed statistical analyses to evaluate its performance and applicability. The survey results indicated that the participants reported a high level of satisfaction (scoring 4 and above on a 5-point Likert scale) in several areas: specialization of safety inspection items for different types of work (with a satisfaction rate of 65%), the evaluation process for safety ratings (64.5%), and their willingness to recommend the procedure to other institutions (75.5%). In the factor analysis with Varimax rotation, two factors emerged: (1) a specialization factor related to safety inspection items, and (2) a grading factor associated with safety evaluation results. Regression analyses of these factors unveiled significant positive relationships with improvements in safety and health performance, including the prevention of fatal accidents, heightened safety responsibility, and raised safety inspection standards. The establishment procedure of safety inspection system developed in our previous study can play a crucial role in reducing accidents resulting in fatalities and injuries at construction sites, ultimately contributing to a safer working environment for all involved parties.

• Journal of Trauma and Injury
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• 제37권2호
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• pp.114-123
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• 2024

Purpose: Appropriate scoring systems can help classify and treat polytrauma patients. This study aimed to validate chest trauma scoring systems in polytrauma patients. Methods: Data from 1,038 polytrauma patients were analyzed. The primary outcomes were one or more complications: pneumonia, chest complications requiring surgery, and mortality. The Thoracic Trauma Severity Score (TTSS), Chest Trauma Score, Rib Fracture Score, and RibScore were compared using receiver operating characteristic (ROC) analysis in patients with or without head trauma. Results: In total, 1,038 patients were divided into two groups: those with complications (822 patients, 79.2%) and those with no complications (216 patients, 20.8%). Sex and body mass index did not significantly differ between the groups. However, age was higher in the complications group (64.1±17.5 years vs. 54.9±17.6 years, P<0.001). The proportion of head trauma patients was higher (58.3% vs. 24.6%, P<0.001) and the Glasgow Coma Scale score was worse (median [interquartile range], 12 [6.5-15] vs. 15 [14-15]; P<0.001) in the complications group. The number of rib fractures, the degree of rib fracture displacement, and the severity of pulmonary contusions were also higher in the complications group. In the area under the ROC curve analysis, the TTSS showed the highest predictive value for the entire group (0.731), head trauma group (0.715), and no head trauma group (0.730), while RibScore had the poorest performance (0.643, 0.622, and 0.622, respectively) Conclusions: Early injury severity detection and grading are crucial for patients with blunt chest trauma. The chest trauma scoring systems introduced to date, including the TTSS, are not acceptable for clinical use, especially in polytrauma patients with traumatic brain injury. Therefore, further revisions and analyses of chest trauma scoring systems are recommended.

• 환경영향평가
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• 제32권6호
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• pp.389-406
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• 2023

본 연구지역은 우리나라 서해북부 초입부로 철새류의 중간기착지로 이용되던 갯벌을 매립하고 조성된 송도국제자유도시에서 조류 이입이 확인된 축소(잔존갯벌, site.1) 및 창출(인공호수, site.2)된 서식지 2개소와 개발 전 부터 안정된 서식지를 유지하고 있는 서식지 1개소(남동유수지, site.3)를 대상으로 실시한 조류군집과 서식환경조사를 기초로 서식지 평가를 실시하고 서식지 관리방안을 제안하였다. 2022년 1월부터 12월까지(총 39차례) 관찰된 조류는 총 14과 48종 20,760개체로 기존 서식지에 비해 새로 조성된 서식지로 이입되는 종과 개체수가 상대적으로 적었고 서식지 평가 중 갯벌등급에서 축소나 창출된 서식지는 I~II등급인 반면 기존 서식지는 상대적으로 높은 III등급으로 평가되었다. 서식지유형에 대한 분석에서 유형별 면적보다는 유형의 다양성과 인위적 간섭에 대한 대책이 확보된 기존 서식지에서 다양한 조류의 서식이 확인 되었는 바, 서식지유형의 다양성이 다양한 조류의 유입에 관여한다는 것을 알 수 있었다. 서식지 관리를 위한 조류종을 선정하고, 선정된 종의 서식특성을 고려한 서식지 유형별 평가를 통한 서식지 관리계획 수립방안으로 주변으로부터 간섭을 최소화할 수 있는 차폐녹지조성(=완충녹지)과 출현종 및 서식지유형간 상관분석을 통해 저수지와 양의 상관관계에 있는 갈대숲의 창출(site.1, 2)과 서식밀도가 높고 주요서식지 유형인 갯벌과 양의 상관관계가 있는 모래톱의 개선(site.1)을 통해 향후 안정된 서식지가 복원 유지될 수 있을 것으로 판단된다. 본 연구를 통해 연구대상지와 입지적이나 환경이 유사한 서해안 간척(매립)지역 등 개발예정지역의 철새류 도래지역에서 적용할 수 있을 것으로 기대된다.

• 한국산업보건학회지
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• 제24권4호
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• pp.501-508
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• 2014

Objectives: This study identified the general characteristics of asbestos inspection/analysis laboratories in Korea and confirmed the actual situations in terms of technical aspects from these characteristics. In addition, given the background of the current problem, it offers preliminary data for determining future plans for improvement. Methods: A questionnaire was developed and distributed to the asbestos inspection/analysis laboratories that used the ISO/IEC 17025 for asbestos sampling and testing by UKAS(United Kingdom Accreditation Service) and the Korea Laboratory Accreditation Scheme(KOLAS). A total of 202 institutions in Korea were selected for the study and 145(71.8%) questionnaires were returned. Results: The number of personnel of the surveyed institutions averaged $4.2{\pm}2$ and 79.3% operated with less than five persons. In terms of education, the capital and other densely populated areas showed a high level of education(p<0.05). The level of education and facilities were determined by the magnitude of the institution(p<0.05). Institutions managed by highly educated directors were well-stocked with education and facilities(p<0.05). Institutions which had directors with considerable experiences received high scores overall and in particular higher scores in terms of education and facilities(p<0.05). At the level of the bottom five percent, the factor of education was 40.4% while the factor of measurement 49%, the factor of analysis 59%, the factor of facilities 61%, and the factor of survey 81%, respectively. Conclusions: To improve the quality of the institutions, in the short term, the problems identified in this study can be used to revise the related regulations. In the long term, a grading system of survey institutions needs to be established through the introduction of an accreditation system. However, the ongoing support of a government agency is required, including holding seminars and open education, suggesting guidelines for operation of asbestos inspection/analysis labs, and other means.

• 한국엔터테인먼트산업학회논문지
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• 제13권6호
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• pp.187-202
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• 2019

본 연구에서는 체육교사 신뢰와 체육수업 몰입 경험이 중학생의 체육교과에 대한 태도와 체육수업 만족에 미치는 영향을 규명함으로써 체육교과에 요구되어지는 사회적 역할에 부응하고 학교체육 활성에 기여하는 데 목적이 있다. 본 연구는 광주광역시에 소재하는 중학교 학생을 대상으로 863명의 유효표본 자료를 분석하였다. 자료 분석은 SPSS window Ver 25 프로그램을 사용하여 빈도분석, 탐색적 요인분석, 신뢰도분석, 상관분석, 다중회귀분석을 실시하였다. 도출된 연구 결과는 다음과 같다. 첫째, 체육교사 신뢰의 하위 요인은 체육교과 태도의 하위 요인에 부분적으로 유의한 정(+)과 부(-)의 영향을 미쳤다. 둘째 체육교사 신뢰의 하위 요인은 체육수업 만족에 하위 요인에 따라 부분적으로 유의한 정(+)의 영향을 미치는 것을 나타났다. 셋째, 체육수업 몰입의 하위 요인은 체육교과 태도에 부분적으로 유의한 정(+)적 영향을 미치는 것으로 확인되었다. 넷째, 체육수업 몰입의 하위 요인은 체육수업 만족의 하위 요인에 부분적인 정(+)의 영향을 미치는 것으로 나타났다. 결과를 종합하면 중학교 학생들의 체육교과에 대한 긍정적 태도 형성과 체육수업 만족 향상에는 체육교사에 대한 학생의 신뢰와 체육수업에 대한 몰입 경험이 중요한 요인으로 작용한다. 관련하여 체육교사는 학생과의 신뢰를 형성하기 위한 노력 즉 다양한 상호작용을 통한 친근한 이미지 구축, 흥미롭고 체계적인 수업구성과 진행, 학생의 특성과 능력을 고려한 수준별 수업 적용 등의 노력이 지속되어야 한다. 또한 학생의 체육수업 몰입 경험을 제고하기 위해서 성과 및 순위 위주의 교육 방식을 지양하고 신체활동 자체에 의미를 부여하는 수업 분위기를 조성하여야 한다. 더불어 학생의 능력을 고려한 운동학습 과제 부여, 수업 집중도를 높일 수 있는 수업내용 선정 등의 노력이 함께 이루어져야 할 것으로 사료된다.

• 한국학교수학회논문집
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• 제11권4호
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• pp.543-567
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• 2008

최근 우리나라 2007 개정 수학교육과정에서는 그동안 강조되어오던 수학적 문제해결력 뿐 아니라 수학적으로 사고하고 의사소통하는 능력을 중요한 요소로 강조하고 있다. 이에 따라 수학과의 평가영역에서는 고등 사고 능력을 평가할 수 있는 대안적인 평가 방법으로 수행평가와 서술형 논술형 평가방법의 구체적인 활용 방안들이 논의되고 있다. 본 연구에서는 초등학교 교과서와 교육과정을 분석하여 <6-나> 단계를 중심으로 서술형 평가 문항과 채점기준을 개발하고 개발된 평가문항을 현장에 적용하여 결과를 분석함으로써 초등학교 수학과 서술형 평가의 현장 적용 가능성을 제시하고자 한다.

• 디지털융복합연구
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• 제11권2호
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• pp.365-374
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• 2013

본 연구는 간호학생들을 대상으로 흡연지식 및 태도, 그리고 금연권고를 조사하고 금연권고에 영향을 미치는 요인을 파악하기 위한 서술적 조사연구이다. 일개 광역시 3개 대학교 간호학과에 재학 중인 간호학생 529명을 대상으로 구조화된 설문지를 이용하여 2012년 10월 1일부터 10월 30일까지 자료를 수집하였다. 연구결과, 간호학생의 금연권고는 학년별, 거주지, 주관적 건강지각, 흡연에 대한 인식, 흡연력 사정 경험, 금연권고 경험, 금연중재교육 참여의사에서 통계적으로 유의한 차이를 보였다. 간호학생들의 금연권고는 흡연지식과 흡연태도와 통계적으로 유의한 상관관계를 보였고 금연권고에 영향을 미치는 요인들은 금연중재교육 참여의사, 흡연태도, 흡연지식, 금연권고 경험으로, 금연권고를 15.5% 설명하였다. 결론적으로 간호학생들이 임상 환자를 대상으로 금연권고를 적극적으로 실천하기 위해서는 학부에서 환자들을 위한 금연중재교육을 실시하여 바람직한 흡연태도와 흡연지식을 증가시키고 임상실습시 금연권고 경험을 갖도록 하는 것이 필요할 것이다.

• 한국식품조리과학회지
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• 제27권6호
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• pp.763-772
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• 2011

This study evaluated the antioxidative activity and quality characteristics of Sulgidduk (traditional rice cakes) prepared with ramie leaf powder, in order to measure the antioxidative activity of ramie leaves, which are a potentially useful antioxidant food. Antioxidant activities were measured by total phenolic contents, the scavenging activities of DPPH radicals and ABTS+ radicals, and the reducing power. The total phenolic content of freeze dried ramie leaves was estimated at $58.70{\pm}11.42mg$ GAE/g. The $IC_{50}$ values for DPPH radicals and the ABTS+ radical scavenging activity of the ramie leaves were $23.76{\pm}1.41ug/mL$ and $174.82{\pm}6.4ug/mL$, respectively. The leaves also showed a high reducing power of $1.1057{\pm}0.03$ (O.D). To increase the utilizability of ramie leaf, we made Sulgidduk with added ramie leaf powder. Re-grading the quality characteristics of the altered Sulgidduk, the 3% and 5% addition levels most satisfied texture profile analysis and sensory evaluation. The antioxidative effect of the Sulgidduk significantly increased as the addition level increased, compared to the original Sulgidduk. In term of DPPH radical scavenging activity, the 5% or more addition level Sulgidduk showed an antioxdative effect increase of more than 50%. At the 3% or higher addition level, there was higher antioxidant activity than in the positive control group, which included vitamin C and BHT additions. We thus concluded that Sulgidduk with added ramie leaf power can be manufactured as a food that can satisfy sensory preferences as well as boosting antioxidant activity, at both the 3% and 5% addition level.