• 제목/요약/키워드: grading analysis

검색결과 402건 처리시간 0.028초

구강편평세포암종의 유세포분석적 DNA측정을 위한 이중 매개변수법의 적용 (APPLICATION OF DUAL PARAMETER ANALYSIS IN FLOW CYTOMETRIC DNA MEASUREMENTS OF ORAL SQUAMOUS CELL CARCINOMA)

  • 김수야;주훈;김재곤;조남표;백병주
    • 대한소아치과학회지
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    • 제23권2호
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    • pp.503-524
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    • 1996
  • A series of 31 patients with primary oral squamous cell carcinoma (SCC) who were treated at Chonbuk National University Hospital during the years 1991-1995, were evaluated by dual parameter analysis in flow cytometric DNA measurement, Bryne's malignancy grading system, and the TNM classification. The aims of the present study were to discover that previously undetected aneuploid clones could be detected by dual parameter analysis and to determine the prognostic value of the above parameters. 1. Using dual parameter analysis of cytokeratin and DNA on disintegrated paraffin-embedded samples, aneuploid clones which were undetected by regular single parameter DNA analysis could be found among the cytokeratin-selected cells. DNA aneuploidy from paraffin-embedded samples were 15 cases compared with 10 cases using conventional DNA analysis. 2. The portion of aneuploid tumors showed slightly higher clinical stage and tumor size than the portion of diploid tumors, but the difference was not significant. The portion of DNA aneuploid tumors showed significantly higher mean mitosis and total malignancy scores than the portion of DNA diploid tumors. 3. The majority of the patients presented with clinical stage III and IV lesions showed significantly higher mean total malignancy score as compared to those with clinical stage I and II. 4. Histopathologic mean total malignancy score of the 31 cases was 12.7. Among the histologic parameters, mean mitosis score was correlated to the status of DNA ploidy and total malignancy score were correlated to the DNA ploidy and clinical staging.

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DITI로 관찰한 Bell's palsy에 미치는 수기요법의 영향에 관한 임상적 연구 (The Clinical study of Su-Gi therapy's Effects on Bell's palsy by observing of DITI)

  • 홍승철;안훈모;이재흥;하정아
    • 대한의료기공학회지
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    • 제15권1호
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    • pp.44-60
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    • 2015
  • Objective : The purpose of this study is to investigate the effect of Su-Gi therapy for Bell's palsy by using DITI. Methods : We investigated 16 patients with Bell's palsy who had visited in the H Korean medicine hospital in Gyeonggi Province from December 27th, 2010 to April 8th, 2015. The Su-Gi therapy was done by 1 times daily. We evaluated the change of them by using Digital Infrared Thermographic Imaging and Yanagihara's unweighted grading system. Results : There aren't meaningful differences in values for the meridian points in pretest and posttest which were observed by DITI of abnormal side and normal side. There are meaningful differences in values, for abnormal side and normal side of the meridian points in pretest and posttest of DITI. It was of significance that pretest Y and average ΔT of each the meridian points in the type of hyperthermia but not in the type of hypothermia. In the Correlation analysis of values of pretest and posttest, chaotic aspects of body heat distribution in the pretest change as a relatively consistent aspects in the posttest. It wasn't of significance that Correlation Analysis of Ups and downs in temperature of TE17 and Recovery speed observed by ΔY. In simple regression analysis of posttest's Y-system values against absolute ΔT by subtracting ΔTE17 from ΔST6, we didn't predict in the pretest, but could predict significantly in the posttest(Regression coefficient : -2.11) In the regression analysis result of the meridian points' ||pretest ΔT|-|posttest ΔT||, 陽白(GB14) and 頰車(ST6) are of significance (Total R-Square=0.447). But we couldn't obtain final regression analysis model. Conclusions: These results suggest that Su-Gi therapy may be effective for Bell's palsy.

배 농가의 경영효율성 분석;비모수적 접근방법에 의한 사례 연구 (An Analysis on Korean Pear Farm Efficiency;A case study using non-parametric method)

  • 우수곤;유진채;강경하;신용광
    • 농촌지도와개발
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    • 제9권2호
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    • pp.263-277
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    • 2002
  • The objective of this study was to compare the farm efficiency of members of cooperative firms with that of non-members in Korea. Data were collected from 27 farms members of three cooperatives and 13 non-member farms, based on the managerial achievements of 1999. For the analysis, the data were divided into three different farming types: type I and II of member farms and non-member farms. Economic analysis were implemented using DEA(Data Envelopment Analysis). Major findings was as follows. Total average technology efficiency was 0.782, which implies that there still remains 21.8% of improvement possibility. Among the three types, type I showed the highest technology efficiency of 0.9055, while type II and non-member farms showed 0.7670 and 0.7171, respectively. This means that these farms have relatively high potential improved. Also, comparing technology efficiency by dividing into pure technology and scale efficiency, all type of the farms exhibit a higher pure technology efficiency compared to scale efficiency. Therefore, to improve current technology efficiency, farms need to focus more on pure technology efficiency improvement. Meanwhile, profit analysis based on farm size indicate that most of the farms demonstrated the increasing-return-to-scale, which means it is necessary to extend the farm size to improve technical efficiency. Type I member farms achieve higher profit and efficiency than other two types and relatively higher producer prices through introducing cooperative sorting, grading and packing. Also, these labor saving technologies increased farm size.

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뇌졸중 환자의 상지에서 근육협응 패턴과 관절협응 패턴의 유사성에 관한 연구 (A Study of Symmetry in the Patterns of Muscle Coordination and Interjoint Coordination in the Upper Limb Activity Among Subjects With Stroke)

  • 이정아;신화경;정이정;조상현
    • 한국전문물리치료학회지
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    • 제13권1호
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    • pp.54-60
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    • 2006
  • This study aimed to compare movement patterns of shoulder joints between the right and left symmetry in stroke patients and control subjects. This study proposes use of the voluntary response index (VRI) calculated from quantitative analysis of surface electromyographic (sEMG) and motion data recorded during voluntary movement as a feeding task. The VRI is comprised of two numeric values, one derived from the total muscle activity recorded for the voluntary motor task (magnitude), and the other from the sEMG distribution across the recorded muscles with the similarity index (SI). Five stroke patients and five age-matched healthy controls were recruited. Feeding motion was performed using the provided spoon five times with rests taken on a chair in between tasks. EMG data were digitized and analyzed on the basis of the root mean square (RMS) envelope of activity. The average amplitude of responses was calculated. Responsiveness and clinically meaningful levels of discrimination between stroke patients and control for EMG magnitude and SI were determined. The similarity index of the results from two successive examinations of both sides apart for stroke patients and control subjects were .86 and .95 in motion analysis and .84 and .99 in electromyographic analysis. The SI of sEMG data and motion data was significantly correlated in stroke patients. The data suggest that SI is a sensitive program for comparing and analyzing the symmetry of muscle activity and motion in both sides. This analysis method has a clinical value in grading muscular activity and movement impairment after brain injury.

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新禮院粘土에 관한 基礎的 硏究 (Fundamental Studies on Sinyewon Clays)

  • 박순자;안남순;김윤호
    • 대한화학회지
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    • 제10권2호
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    • pp.67-75
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    • 1966
  • Four kinds of clays from Sinyewon mine which is located in Chungchoungnam-Do district and two kinds of Japanese clays (Gairome, Kibushi) were selected and studied on the fundamental properties of these clays and those which are refined by the elutriation method. Chemical analysis, grading analysis such as refractoriness, specific gravity, color, fired color and plasticity, particle size distribution, various thermal tests, X-ray diffraction analysis and electron microscopic survey were carried out on these clays. The comparison of domestic clays with Japanese clays was made. 1. In chemical composition and physical properties, these four kinds of Sinyewon clays are almost similar to each other and also to Gairome and Kibushi clays. In refractoriness, Gairome and Kibushi clays have relatively high value such as SK 34 and 35, while Sinyewon clays have the value of about SK 32. Especially Sinyewon clay B has the low refractoriness (SK 18) and plasticity. Refined clays have the tendency of somewhat higher value than crude ones in refractoriness. 2. When burnt up to $900^{\circ}C$, the coefficients of contraction of Sinyewon clays were under 1.5%, Gairome under 1.3%, Kibushi under 3.0%. Only Sinyewon clay B showed expansion (1.0%) instead of contraction. 3. X-ray diffraction analysis and electron micrography showed that all of four Sinyewon clays and two Japanese clays are mainly composed of poorly crystallized kaolin, containing small amount of halloysite, sericite and considerable amount of quartz and feldspar. Sinyewon clay B contains especially large amount of quartz and feldspar. In general, it has been found out that the refined clays were free from large amount of iron oxide, quartz and feldspar.

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중국(中國) 성인남성용(成人男性用) 의류치수규격(衣類値數規格) 설정연구(設定硏究) I (A Study on Development of Chinese Men's Apparel Sizing System)

  • 손희순;임순;김지연
    • 패션비즈니스
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    • 제8권1호
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    • pp.1-15
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    • 2004
  • The purpose of this study is to provide for some basic data useful to production of the apparels fit and measured well for the Chinese men. For this purpose, Chinese men's apparel measurements and specifications were determined per area group(Beijing/ Shanghai) according to the Men's Wear Specifications (GB/T 1335.1-1997), National Standards of People's Republic of China. The collected data were statistically processed using SAS 6.12 for technical statistical analysis, correlation analysis, factor analysis, group-wise analysis and ANOVA. The results of this study can be summarized as follows; 1. As a result of dividing the Chinese men into Beijing and Shanghai men and thereby, setting height and upper chest circumference for upper garments and height and waist for lower garments. 2. Analyzing the correlations according to the three-fold classifications of height/upper chest circumference/waist for garment specifications, 17 specifications based on heights and upper chest circumferences for Beijing men's upper garments could be designed within the deviation level of 2%, while 15 specifications based on waist measurements could be designed (between $70{\sim}98cm$) for their lower garments within the deviation level of 4%. Thus, a total of 60 combinations of the specifications could be obtained. 3. 16 specifications based on heights and upper chest circumferences for Shanghai men's upper garments could be designed within the deviation level of 2%, while 16 specifications based on waist measurements could be designed (between $68{\sim}98cm$) for their lower garments within the deviation level of 3%. Thus, a total of 56 combinations of the specifications could be obtained. For other reference measurements, grading measures were set for each type and body part, while the average measures of major body parts were calculated.

금호강 수계 지류하천의 수질 특성 평가 및 수질개선 등급화 방안 (Evaluation of Water Quality Characteristics and Water Quality Improvement Grade Classification of Geumho River Tributaries)

  • 정강영;안정민;김교식;이인정;양득석
    • 한국환경과학회지
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    • 제25권6호
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    • pp.767-787
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    • 2016
  • In this study, we analyzed on-site monitoring data for 15 tributaries in Geumho watersheds for 3 years (2011-2013) in order to sort out priorities on water quality characteristics and improvement. As a result of estimating contribution to contamination of the tributary rivers, Dalseocheon showed the highest load densities, despite the smallest watershed area, with 22.7% $BOD_5$, 30.7% $COD_{Mn}$, 31.3% TOC and 47.6% TP. After conducting PCA (principal component analysis) and FA (factor analysis) to analyze water quality characteristics of the tributary rivers, the first factor was classified as $COD_{Mn}$, TOC, EC, TP and $BOD_5$, the second factor as pH, Chl-a and DO, the third factor as water temperature and TN, and the fourth factor as SS and surface flow. In addition, arithmetical sum of each factor's scores based on grading criteria revealed that Dalseocheon and Namcheon were classified into Group A for their highest scores - 96 and 93, respectively -, and selected as rivers that require water environmental management measures the most. Also, water environmental contamination inspection showed that Palgeocheon had the most number of aquatic factors to be controlled: $BOD_5$, $COD_{Mn}$, SS, TOC, T-P, Chl-a, etc.

Short-course Versus Long-course Preoperative Radiotherapy plus Delayed Surgery in the Treatment of Rectal Cancer: a Meta-analysis

  • Liu, Shi-Xin;Zhou, Zhi-Rui;Chen, Ling-Xiao;Yang, Yong-Jing;Hu, Zhi-De;Zhang, Tian-Song
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권14호
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    • pp.5755-5762
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    • 2015
  • Background: Short-course preoperative radiation (SCRT) with delayed surgery was found to increase pathologic complete response (pCR) rates in several trials. However, there was no clear answer on whether SCRT or long-course chemo-radiotherapy (LCRT) is more effective. Therefore we conducted this meta-analysis to evaluate the safety and efficacy of SCRT versus LCRT, both with delayed surgery, for treatment of rectal cancer. Materials and Methods: The literature was searched from PubMed, EMBASE, Web of Science, Cochrane Library and clinicaltrials.gov up to November, 2014. Quality of the randomized controlled trials (RCTs) was evaluated according to the Cochrane's risk of bias tool of RCT. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) system was used to rate the level of evidence. Review Manager 5.3 was employed for statistical analysis. Pooled risk ratios (RRs) and 95% confidence intervals (CIs) were calculated. Results: Three RCTs, with a total of 357 rectal cancer patients, were included in this systematic review. Metaanalysis results demonstrated there were no significantly differences in sphincter preservation rate, local recurrence rate, grade 3~4 acute toxicity, R0 resection rate and downstaging rate. Compared with SCRT, LCRT was associated with significant increase in the pCR rate [RR=0.49, 95%CI (0.31, 0.78), P=0.003]. Conclusions: In terms of sphincter preservation rate, local recurrence rate, grade 3~4 acute toxicity, R0 resection rate and downstaging rate, SCRT with delayed surgery is as effective as LCRT with delayed surgery for management of rectal cancer. LCRT significantly increased pCR rate compared with SCRT. Due to risk of bias and imprecision, further multi-center large sample RCTs were needed to confirm this conclusion.

SNS의 교육적 활용 방법에 대한 대학생들의 인식 분석 (An Analysis of the Awareness of Undergraduate Students Toward Educational Methods Utilizing SNS)

  • 정미현;김영록;김재현
    • 인터넷정보학회논문지
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    • 제15권5호
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    • pp.33-41
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    • 2014
  • 본 연구는 효과적인 SNS의 교육적 활용 방안을 제안하고자 SNS의 사용률이 높은 대학생들을 대상으로 구체적인 SNS의 교육적 활용 방법에 대한 의견과 그 이유에 대해 조사하였다. NVivo S/W를 이용하여 개방형 응답을 분석하였으며, 교육 주체별 SNS의 교육적 활용 방법을 가시화 하고자 교수자 영역과 학습자 영역, 공통 영역으로 범주화 하였다. 그 결과 공통 영역에는 의견 교류 및 토론, 정보 공유, 학습내용에 대한 질의응답, 설문조사, 친밀감 형성, 상담 등이 포함되었으며, 교수자 영역에는 공지사항 전달, 수업자료 제공, 실시간 평가(퀴즈), 출석 체크, 과제평가 및 피드백 등이 포함되었고, 학습자 영역에는 과제활동(그룹별/개인별), 공유자료를 이용한 예습 및 복습, 동영상을 이용한 자율학습, 과제에 대한 동료평가 및 피드백, 강의 평가 등이 포함되었다.

A meta-analysis on advantages of peripheral nerve block post-total knee arthroplasty

  • You, Di;Qin, Lu;Li, Kai;Li, Di;Zhao, Guoqing;Li, Longyun
    • The Korean Journal of Pain
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    • 제34권3호
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    • pp.271-287
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    • 2021
  • Background: Postoperative pain management is crucial for patients undergoing total knee arthroplasty (TKA). There have been many recent clinical trials on post-TKA peripheral nerve block; however, they have reported inconsistent findings. In this meta-analysis, we aimed to comprehensively analyze studies on post-TKA analgesia to provide evidence-based clinical suggestions. Methods: We performed a computer-based query of PubMed, Embase, the Cochrane Library, and the Web of Science to retrieve related articles using neurothe following search terms: nerve block, nerve blockade, chemodenervation, chemical neurolysis, peridural block, epidural anesthesia, extradural anesthesia, total knee arthroplasty, total knee replacement, partial knee replacement, and others. After quality evaluation and data extraction, we analyzed the complications, visual analogue scale (VAS) score, patient satisfaction, perioperative opioid dosage, and rehabilitation indices. Evidence was rated using the Grading of Recommendations Assessment, Development, and Evaluation approach. Results: We included 16 randomized controlled trials involving 981 patients (511 receiving peripheral nerve block and 470 receiving epidural block) in the final analysis. Compared with an epidural block, a peripheral nerve block significantly reduced complications. There were no significant between-group differences in the postoperative VAS score, patient satisfaction, perioperative opioid dosage, and rehabilitation indices. Conclusions: Our findings demonstrate that the peripheral nerve block is superior to the epidural block in reducing complications without compromising the analgesic effect and patient satisfaction. Therefore, a peripheral nerve block is a safe and effective postoperative analgesic method with encouraging clinical prospects.