• 약학회지
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• 제48권6호
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• pp.384-390
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• 2004

Polyphenol oxidase-catalyzed oxidation of substrates (t-butylcatechol, 4-methylcatechol, chlorogenic acid, caffeic acid and pyrocatechol) were performed in the Ph range 4~8. Co ncentrations of substrate's major oxidation products were monitored by high performance liquid chromatograph. The nature and amounts of products formed were highly pH dependent. They also were ifluenced by kinds of substrates. Major oxidation product of 4-methylcatechol appeared the maxium value at pH 5, them of chlorogenic acid, caffeic acid and pyrocatechol at pH 6.0 and that of t-butylcatechol at pH 5~7. Time-dependent PPO activity was determined at $4^{\circ}C\;and\;30^{\circ}C$. PPO extracted by phosphate buffer containing triton X-114 (t-PPO) was more stable than PPO by phosphate buffer (b-PPO). The result of electrophoresis, at first PPO was showed only a band at 48 kd. After 1~3 days a partial degrade band was appeared in b-PPO and three partial degrade bands in t-PPO. No activity band was appeared in PPOs at $30^{\circ}C$ and b-PPO at $4^{\circ}C$ after 4 days. And a band (37 kDa) in t-PPO was remained finally and disappered. PPO from Perillae leaves has two activity bands at 48 and 37 kDa in previous paper. It was supposed that PPO in the leaves of Perilla frutescens was a protein having one molecular weight as 48 kDa. And 37 kDa protein, relatively proteolysis-resistant, was a proteolyzed form of a major form.

• 간호행정학회지
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• 제23권2호
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• pp.211-222
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• 2017

Purpose: To develop staffing levels for nursing personnel (registered nurses and nursing assistants) to provide inpatients with integrated nursing care that includes, in addition to professional nursing care, personal care previously provided by patients' families or private caregivers. Methods: A time & motion study was conducted to observe nursing care activities and the time spent by nursing personnel, families, and private caregivers in 10 medical-surgical units. The Korean Patient Classification System-1 (KPCS-1) was used for the nurse manager survey conducted to measure staffing levels and patient needs for nursing care. Results: Current nurse to patient ratios from the time-motion study and the survey study were 1:10 and 1:11, respectively. Time spent in direct patient care by nursing personnel and family/private caregivers was 51 and 130 minutes per day, respectively. Direct nursing care hours correlated with KPCS-1 scores. Nursing personnel to patient ratio required to provide integrated inpatient care ranged from 1:3.9 to 1:6.1 in tertiary hospitals and from 1:4.4 to 1:6.0 in general hospitals. The functional nursing care delivery system had been implemented in 38.5% of the nursing units. Conclusion: Findings indicate that appropriate nurse staffing and efficient nursing care delivery systems are required to provide integrated inpatient nursing care.

• 한국환경보건학회지
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• 제39권4호
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• pp.346-353
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• 2013

Objectives: The goal of this study is to identify the distribution of the foliar fluorine content of vegetation surrounding the area where hydrofluoric acid was accidently released in Gumi, Gyeongsangbuk-do on September 27, 2012. In addition, it also aims to estimate the concentration of hydrogen fluoride in the air on the day of the accident. Methods: Samples of plant leaves were collected on October 7, 2012 within 1 km from the site where the accident occurred. These samples were analyzed for soluble fluorine ion with an ion selective electrode. The ambient concentration of hydrogen fluoride was calculated using the fluoride content in the plant via the dose-rate equation (${\Delta}F$=KCT). Results: The arithmetic and geometric means of the concentrations were 2158.2 and 1183.7mg F $kg^{-1}$ for leaves and, 2.4 and 1.1 ppm HF for the air, respectively. The highest concentration of hydrogen fluoride in the air was 14.7 ppm, which is higher than the maximum concentration reported by the government (1 ppm) and the exposure limit (ceiling, 3 ppm). The concentrations of both fluorine and hydrogen fluoride decreased with increasing distance from the accident site and showed a significant decrease outside of a 500m radius from the site (p <0.05). Conclusions: The area around the accident site was highly polluted with hydrogen fluoride according to the results of this study. Considering the persistency of hydrogen fluoride in the environment, long-term monitoring and environmental impact assessment should be pursued.

• 생물환경조절학회지
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• 제23권4호
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• pp.391-400
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• 2014

The number of large scale greenhouses has recently been increasing to cope with mass consumption of agricultural product. Korean government announced a new development plan for constructing greenhouse complex in reclaimed lands for the purpose of improvement in exports and activation of domestic market of agricultural product. Wind environment in the reclaimed land is totally different from that of inland area, and it can give a strong influence on ventilation performance of naturally ventilated greenhouse facilities. In this study, internal airflow analysis of naturally ventilated greenhouse built on a reclaimed land was conducted using wind tunnel and PIV for validation research. Later, the PIV measured results will be used to improve the accuracy of 3 dimensional CFD simulation in the future. Wind profile at a reclaimed land was produced using ESDU program and it was applied to the wind tunnel. The calculated error was only 5% and 0.96 of correlation coefficient, implying that the computed profiles were designed properly. From the measured results, when external wind speed changed from $1m{\cdot}s^{-1}$ to $1.5m{\cdot}s^{-1}$, air velocities inside the greenhouse which PIV measured were also increased proportionately in case of both side vent open and side-roof vent open. Considering reduced ratio of air velocity inside the greenhouse, it was measured a minimum of 40% in case of side vent and 30% in case of side-roof vent compared with external wind speed from each vent type. From the quantitative and qualitative PIV analysis, the PIV measured results indicated that there were well ventilated and stagnant areas in the greenhouse according to external wind condition as well as ventilation design.

• 한국지역사회생활과학회지
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• 제23권4호
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• pp.419-439
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• 2012

Family dissolution and economic difficulties of the grandchild's parents are the most prevailing reason for an increase of grandparent-headed families in rural Korea. However, there is a lack of empirical research looking at the experiences of custodial grandmothers, social support, and their psychological well-being. In this regard, this study examined the effect of social support (formal & informal) on the psychological well-being of custodial grandmothers in rural Korea. For this purpose, quantitative and qualitative research methods were conducted. Quantitative data were gathered, using structured questionnaire, from 311 grandmothers who were raising their grandchildren in rural Korea as primary care-givers. Statistical methods used for data analysis were descriptive statistics and hierarchical regression analysis with SPSS WIN 19.0 programs. Qualitative data were collected by in-depth interviews to 10 custodial grandmothers in rural area. The results of this study are as follows. First, almost half of the parents of the grandchild didn't visit and didn't call anymore. Some relatives -aunt, uncle, etc.- support the grandparent-headed family economically and emotionally. 3/4 of the grandparent-headed families were supported by the government and community. This was not small numbers, but the amount of economic support was low. Second, grandmothers in the study showed quite a high level of depression while their happiness level was relatively low. There were differences in the factors influencing the level of happiness/depression of these rural grandmothers. Overall, the study's results showed the importance of formal & informal support for psychological well-being of the custodial grandmothers in rural Korea. Policy and theoretical implications are discussed.

• 수산해양교육연구
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• 제28권1호
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• pp.34-46
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• 2016

This study analyzes inspection results of ships by Port State Control. Particularly, this research focuses on a detention trend of vessels that registered to Korean Register of Shipping. In order to conduct this research, we have searched 170 ships that got a detention with a Code-30 within recent 46 months period. The deficiencies of the detentions are inspected by ship types, ship years, flags, ports inspected, and criteria. Moreover, we categorized the deficiencies for the detentions into 17 types for internal and external inspections. As the results of the comparison study, bulk and general cargo carriers dominate the portion of detentions by almost 66 percent. Self-induced detention due to a lack of preparation by crews and company support are the main reasons of repeated detentions from the same type ships. Ships between six and ten years old show the lowest detention rate by 4 percent whereas ships less than five years old generate the highest detention rate by 22 percent. The main categories of the detentions from ships less than 5 years old are a lack of documentation and certification, and the clues support our opinion that owners and crews may neglect to prepare the inspections because their strong confidence for the ship condition due to young ship age. As a result of a great effort of Korean government and shipping companies to reduce a detention rate, the detention rate has been recently reduced to 0.3 percent. The results also require companies with the flag of convenience ships to spend more effort to reduce the detention rate, too. We expect that using social networking service by Korea Register will lower the detention rate by sharing relevant information real-time to ships and owners.

• 한국임상약학회지
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• 제24권3호
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• pp.183-192
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• 2014

Purpose: This study was aimed to identify the status of utilization of healthcare services and self-care behaviors, knowledge level and influencing choice factors of non-prescription drugs (OTCs) on consumers since sales of OTCs at the outside of pharmacy in Korea, and to confirm the changes in perception of consumers for OTCs policy through check of perception level for current OTCs policy. Methods: Data was collected from April 2014 to May 2014 from questionnaires by 418 adults who are in university located in Seoul or live in Seoul Metropolitan area but not health science major and healthcare providers. Results: The female gender was 56.6% and University students were 73.9%. The ratio by age was as follows: below 25 (60.9%), 26-30 (18.2%), 30-40s (14.9%) and 50-60s (6.0%). The knowledge level of OTCs for use of medicine, dose and side effects was generally low and especially they knew little how to deal with side effects after taking OTCs on sale at the outside of pharmacy, even though over one year has passed since the policy. The proportion of those who thought the current OTCs policy has problems regarding safety issues since the policy was very high and it was also high that the study group thought there are problems with the current way to sale OTCs and educate employees. Conclusion: After selling OTCs at the outside of pharmacy, the consumers still lacked knowledge of OTCs and did not get correct information properly. Especially, they had little information about the way to deal with side effects after taking OTCs. Public policy should be based on the health of the people and the public health is a national health priority. When all these things are taken into consideration, the government has to strengthen the OTCs policy and provide a safer environment with the accurate drug information for people than developing OTCs policy in the future.

• 한국안전학회지
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• 제15권1호
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• pp.72-79
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• 2000

In recent, occupational diseases in harmful working places become a social issue. It is the well-known fact that a respiration in polluted working places exert a serious effect on health of workers. Accordingly, the cutting off contaminants air originally is the best way to improve working environments. In these cases, ventilation systems should be essentially installed to dilute or exhaust the contaminated indoor air. In this study, we investigated the characteristics of ventilation system of the noxious gas in working indoor places with natural ventilation by using COMET. The numerical simulations were carried out the natural ventilation with two phase(air, dust). For turbulent flow, Reynolds stresses were closed by the standard $\kappa$-$\varepsilon$ model. The results are as follows ; 1) In the natural exhaust in the working place, the flows of the central region have a more rapid velocity vector than the right and left one. 2) Numerical results show that the distribution of contaminants concentration have greater influence on convection than the case of diffusion by government of velocity vectors. 3) To observe the velocity variation with distance, three location of distance are considered. As results, it shows that the velocity are 0.075(m/s) at y=5(m), 10(m) and mean concentration are raised 10.6% at y=5(m), 10(m). 4) We have presented the useful data for the adequate counterplan in the harmful working places by carrying out the various investigation of the natural ventilation.

• 의학교육논단
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• 제20권2호
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• pp.103-111
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• 2018

In the ever-changing medical environment, the social participation of medical doctors is becoming more necessary. Currently, there is not enough participation or action by doctors within our society due to reasons such as a lack of educational curriculum in this area. This study aimed to investigate medical students' opinions and attitudes about social participation and action. A total of 438 medical students were surveyed about their attitudes toward doctors' relations with the public, social participation, social action, and medical education for social participation or action. Regarding doctors' relations with the public, participants responded that the government (73.5%) and the media (82.0%) were causing social distrust of doctors, and more than 70% of the respondents answered that doctors were passive when it comes to social participation. When asked about social participation and social action, 76.7% of the students surveyed had experienced social participation, and 28.3% had experienced taking social action. A total of 73.4% of the students answered that medical education needs to be changed, and it is necessary to introduce subjects such as sociology and law to improve social participation and action. The results are significant in that they show medical students' thoughts on social participation and social action as doctors in the Fourth Industrial Revolution. We believe that a change of medical curriculum to promote active and collaborative social participation by doctors is necessary.

• 한국지역사회생활과학회지
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• 제14권3호
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• pp.89-98
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• 2003

To assess the actual status of businesses selling fermented soybean products, this study surveyed 130 Farmhouse style small size soybean sauce processing sites supported by the Rural Development Administration nationwide. The sex composition of the businesses representatives of 2% male and 98% female showed that a farmhouse soybean processing business is generally operated by rural women as a non-filming business. The percentage of co-worked sites was 71.2 and that of sites with permits was 39.2. The main products were meju, doenjang, and kanjang. Total production volume was found to be 523 tons, 256 tons, and 135 k$\ell$s, respectively. The number of years of experience of the manufacturers of the kanjang and doenjang was found to be 25.7 on average which shows that long-experienced, skilled manufacturers are participating in this project. The traditional measuring unit differed greatly depending on the region. This difference in the measuring unit of soybeans resulted in a large difference in the volume of doenjang and kanjang produced Per Province. For one kg of raw soybeans, the weight of Doenjang produced also varied from 2.14 kg in the Gyeongbuk area to 1.62 kg in Jeju. In the aspect of salt use, 1.75 $\ell$ (translated by volumetric unit 0.704 due) of salt pet kg of meju, in Jeju, was the highest in Korea. Government supervision would be beneficial in the areas of raw material products, standardization of measuring units and production methods, organization and operation of a conference for the different groups of producers, and in construction of a nationwide database.