• 제목/요약/키워드: glycerin

검색결과 212건 처리시간 0.036초

액체성 화학작용제의 흡수를 차단하는 피부보호제 제제 설계 연구 (Study on the formulations for Topical Skin Protectant against Liquid-Phase Chemical Warfare Agents)

  • 김상웅;서동성;손홍하;유치호;조혜은;조영
    • 한국군사과학기술학회지
    • /
    • 제25권2호
    • /
    • pp.210-217
    • /
    • 2022
  • Chemical warfare agents(CWA) such as nerve agents and vesicating agents show lethality by skin contamination. Skin protection, therefore, is one of the top priorities to deal with the growing threat from CWA. In an attempt to develop the most effective topical skin protectant(TSP), candidate substances including PFPE(perfluorinated polyether), PTFE(polytetrafluoroethylene), glycerin, and polysaccharides were evaluated in forms of various formulations against nerve agent simulant DMMP(dimethylmethyl phosphonate) penetration. The protective efficacy of the formulation against DMMP penetration was estimated as the onset time of color change of the KM9 chemical agent detection paper. Based on this study, it was found that several PFPE- and glycerin-based formulations exhibit remarkably superior efficacy as a protective cream. This protective cream is expected to be used as TSP for military application after further research.

솔비톨 혼합물과 글리세린 가소제에 의한 분리 대두단백질 필름의 특성연구 (Characteristics of Soy Protein Isolate Films Plasticized by Mixtures of Crystalline and Aqueous Sorbitol or Glycerin)

  • 김기명;;최원석;조성환;최성길
    • 한국식품저장유통학회지
    • /
    • 제13권3호
    • /
    • pp.285-291
    • /
    • 2006
  • 가소제로서 솔비톨 혼합물의 첨가가 분리대두단백 필름의 수분흡습특성, 수분투과도, 색, 인장강도 및 신장률, 그리고 용해 특성에 미치는 영향을 조사하였다. 솔비톨 혼합물은 액상형과 결정형의 상태로 다양한 비율로 혼합하여 첨가하였고, 가소제로 글리세린을 첨가한 대조구 필름의 물리적 특성과 비교하였다. 솔비톨이 첨가된 필름은 대조구 필름에 비해 높은 인장강도를 갖는 반면 낮은 수분투과도 및 신장률을 보였다. 한편 솔비톨 첨가 형태에 따른 영향은 필름 신장률에는 유의적 차이는 보였으나 기타 수분투과도, 색, 인장강도 등의 필름특성에는 커다란 차이는 보이지 않았다. 솔비톨 첨가된 필름은 높은 수분차단 효과 및 필름강도를 갖는 대신 높은 용해성을 보여, 상업적 활용성을 증진시키기 위해서는 이를 극복하는 연구가 필요할 것으로 사료된다.

포장어묵의 수분활성저하에 미치는 식품첨가제의 영향 3. 식품첨가제의 병용효과 (Effect of Food Humectant on Lowering Water Activity of Casing Kamaboko 3. Effect of Humectants Used in Combination)

  • 정혜경;김동조;천석조;조길석;박영호
    • 한국수산과학회지
    • /
    • 제16권2호
    • /
    • pp.88-96
    • /
    • 1983
  • 식염, sodium lactate, glycerin, propylene glycol 및 sorbitol의 5종의 첨가제를 두 종류씩 일정 비율로 혼합하여 첨가함으로써 이들 혼합첨가제의 수 분활성 저하효과를 조사하였다. 이들 첨가제에 NaCl을 일정 비율로 혼합첨가한 경우가 다른 첨가물에 비하여 저하효과가 현저히 좋았으며, sodium lactate의 첨가량 증가에 따른 수분활성저하효과는 식염의 1/2 정도로 나타나며, glycerin, propylene glycol, sorbitol 보다는 우수하였다. glycerin과 propylene glyco1을 다른 첨가물에 일정 비율로 증가시키면서 첨가하였을 경우의 수분활성저하효과는 glycerin이 propylene glycol보다 약간 좋았으나, 그 차이는 극히 미미하였다. 5종의 첨가제 중에서 sorbitol의 첨가량 증가에 따른 수분활성 저하효과가 가장 적게 나타났다. 실제 측정된 수분활성치와 Raoult의 식에 의한 계산치와 비교 검토한 결과는 첨가량이 적은 범위에서는 거의 일치하는 경향을 볼 수 있으나 첨가량이 증가할수록 실측치와 많은 차이를 나타내고 있어 어묵의 수분활성 예측법으로는 부적합하다고 생각되었다. 그래서 직선경사법에 이론적 근거를 두어 각종 첨가제에 있어서 수분활성 저하효과를 예측하기 위한 예측식을 구하여 보았다.

  • PDF

식물성 유지류에 침지된 FA 치환 시멘트 모르타르의 품질변화 (Property Change of Cement Mortar Incorporating FA by Immerging Vegetable Oil)

  • 백철;이제현;황찬우;한인덕;한민철;한천구
    • 한국건축시공학회:학술대회논문집
    • /
    • 한국건축시공학회 2016년도 춘계 학술논문 발표대회
    • /
    • pp.147-148
    • /
    • 2016
  • Generally, the vegetable oil contains glycerin esther and free fatty acid. When the vegetable oil reacts with concrete, the glycerin esther from oil induces saponification by reacting with and hydrolyzing calcium hydroxide from cement hydration. As a result of this saponification, it has been reported the expansion of concrete. although the free fatty acid from vegetable oil, as an acid, can decompose the concrete by producing soluble salt from calcium hydroxide or CSH, the hydration products of cement, there was no report on the harmful oil type for concrete. therefore, in this research, the property change of cement mortar incorporating fly ash was analyzed experimentally by immerging various types of vegetable oils.

  • PDF

뉴턴유체와 비뉴턴유체의 원심펌프성능특성 비교 (Comparison of Centrifugal Pump Performances for Newtonian and Non-Newtonian Fluids)

  • 김동주;노형운;서상호
    • 유체기계공업학회:학술대회논문집
    • /
    • 유체기계공업학회 2004년도 유체기계 연구개발 발표회 논문집
    • /
    • pp.57-62
    • /
    • 2004
  • In the current study the effects on pump performances of a conventional centrifugal pump for Newtonian and non-Newtonian fluid were experimentally studied. The study aimed to compare the pump characteristics for Newtonian and non-Newtonian fluid. The working fluids are water, aqueous sugar solution, glycerin solution, muddy solution and pulp solution. The pump characteristics with high viscosity fluids were different. The operating efficiency for the sugar and glycerin solutions were decreased to $8.1\%$ and $12.9\%$ than that of water. The head reductions of the muddy solution for different concentration ratios were decreased to $7.97\%,\;15.11\%$ and $24.87\%$ than that of water And the head reductions of the pulp solution for different concentration ratios were decreased to $11.87\%,\;19.79\%$ md $36.81\%$ than that of water.

  • PDF

실험적(實驗的) 요세관증(尿細管症)에 있어서 신장염유발(腎臟炎誘發)에 관(關)한 병리조직학적(病理組織學的) 연구(硏究) (Histopathological Studies on Nephritis Produced in Experimental Tubular Nephrosis)

  • 임창형
    • 대한수의학회지
    • /
    • 제7권2호
    • /
    • pp.19-24
    • /
    • 1967
  • Normal Albino rats were received glycerin via subcutaneously and Staphylococcus aureus intravenously. The microorganism was coagulase-positive and non-hemolytic. The rats received glycerin alone showed an acute tubular nephrosis, and the others such as glycer in induced nephrotic rats showed a number of different findings: At the first hours of the bacterial injection, in medulla, the bacterial clumps and inflammatory cell infiltration, and microabscesses with retrogressive changes of proximal convoluted tubulles were observed. The suppurative inflammation was observed in days. Five weeks after the initial innoulation of the organism kidney was shown restoration to a histologically normal cortex. The proliferation of fibrous connective tissue and small numbers of chronic inflammatory cells were observed in the medulla where an acute inflammatory process was enhanced presumably. On the other hand, the Albino rats administered Staphyloceccus aureus alone resulted in n moderate degree of vacuolization in proximal convoluted tubules and a number of casts in the early stage. No, bacterial clumps and microabscesses were observed in the rats.

  • PDF

Gum류의 연고제제와 흡수촉진제가 Riboflavin의 경피흡수에 미치는 영향 (Transdermal Permeation of Riboflavin in Ointment Bases Using Gums & Enhancers)

  • 오세영;황성규;김판기
    • 한국환경보건학회지
    • /
    • 제26권2호
    • /
    • pp.91-96
    • /
    • 2000
  • We investigated characters of transdermal therapeutic system(TTS) and the skin permeability of that with applying drug delivery system(DDS). Natural gums were selected as material of TTS. The permeation of natural gums ointment containing drug in rat skin using diffusion cell model. Permeation properties of materials were investigated for water soluble drug such as riboflavin in vitro. We used glycerin, PEG 600 and oleic acid as enhancers. Since dermis has more hydration than the stratum corneum, skin permeation rate at steady state was highly influenced when glycerin was used in riboflavin. The permeation rate of content enhancer and drug was found to be faster than that of content riboflavin only. These results showed that skin permeation rate of drug across the composite was mainly dependent on the property of ointment base and drug. All the gum ointment tested showed good safety. Proper selection of the materials which resemble and enhance properties of the delivering drug was found to be important in controlling the skin permeation rate.

  • PDF

Measurement of Thermal Conductivity of Foods in Liquid and Solid Phase Using a Thermal Probe

  • Hong, Ji-Hyang;Han, Young-Joe;Chung, Jong-Hoon
    • Food Science and Biotechnology
    • /
    • 제14권3호
    • /
    • pp.334-339
    • /
    • 2005
  • An instrument using thermal probe method was designed to measure thermal conductivity of liquid and solid foods. Thermal conductivity probe was designed with diameter to length ratio of 100 and diameter of 0.51 mm to minimize axial flow effect on thermal conductivity measurement. Thermal conductivities of distilled/deionized water, glycerin, and beef frankfurter meat were measured at $20-80^{\circ}C$. Mean thermal conductivity values of water showed less than 2.0% difference from several reference values without using time correction factor or probe calibration constant. For glycerin, difference was less than 0.7% from reference values at $20-50^{\circ}C$. Mean values of thermal conductivity for beef frankfurter meat ranged from 0.389 to $0.350\;W/m{\cdot}K$ at $20-80^{\circ}C$.