• Title/Summary/Keyword: global damage process

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Large Scale Gene Expression Analysis in Rat Models of 4-Vessel Occlusion Ischemia (4-Vessel Occlusion 허혈동물모델에서의 대규모 유전자 발현 연구)

  • Kang, Bong-Joo;Hong, Seong-Gil;Kim, Yun-Taik;Kim, Young-Ok;Cho, Dong-Wuk
    • Korean Journal of Oriental Medicine
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    • v.6 no.1
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    • pp.89-98
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    • 2000
  • Cerebral ischemia, the most prevalent form of clinical stroke, is a medical problem of the first magnitude. Substantial efforts are being made to develop drugs which will protect the brain from the neurodegeneration followed by an ischemic stroke. A key factor in this process is the development of animal models that mimic the neuropathological consequences of stroke. Recently, there is increasing an evidence that free radical is involved in the mechanisms of ischemic brain damage. We investigated the macro scale gene expression analysis on the global ischemia induced by 4-vessel occlusion in Wister rats. The recent availability of microarrays provides an attractive strategy for elaborating an unbiased molecular profile of large number of genes during ischemic injury. This experimental approach offers the potential to identify molecules or cellular pathways not previously associated with ischemia. Ischemia was induced by 4-vessel occlusion for 10 minutes and reperfused again. RNA from sham control brain and time-dependent ischemed brain were hybridized to microarrays containing 4,000 rat genes. 589 genes were found to be at least 2 fold regulated at one or more time points. These survey data provide the foundation studies that should provide convincing proof for ischemia and oxidative stress on gene expression.

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Investigation Study of Information Improvement in Chemical Accident by Extraordinary Chemical Reaction (이상반응 화학사고 정보제공 개선 연구)

  • Kim, Sungbum;Lim, Myunghee;Park, Joongdon
    • Journal of the Society of Disaster Information
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    • v.11 no.2
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    • pp.219-225
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    • 2015
  • Hydrofluoric acid leakage accident was occurred on Dec. 2012 in Hube Global. That accident has bought many changes of response in national organizations. Chemical companies respond quickly even when small quantities leakage of chemicals and response agencies were put a lot of manpower and equipment in incident response. Incident response to the response activities of the agents is difficult if the accident substance was not identified. Unknown chemicals can be generated by the water for fire-fighting during the emergency response process. In this case, an additional information was needed for response of chemical accident to prevent of great damage. In this study, we investigated the improvement of chemical accident information by extraordinary chemical accident.

A Study on Development of Automatic Westing Software by Vectorizing Technique (벡터라이징을 이용한 자동부재배치 소프트웨어 개발에 관한 연구)

  • Lho T.J.;Kang D.J.;Kim M.S.;Park Jun-Yeong;Park S.W.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.10a
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    • pp.748-753
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    • 2005
  • Among processes to manufacture parts from footwear materials like upper leathers, one of the most essential processes is the cutting one optimally arranging lots of parts on raw footwear materials and cutting. A new nesting strategy was proposed for the 2-dimensional part layout by using a two-stage approach, where which can be effectively used for water jet cutting. In the initial layout stage, a SOAL(Self-Organization Assisted Layout) based on the combination of FCM(Fuzzy C-Means) and SOM was adopted. In the layout improvement stage, SA(Simulated Annealing) based approach was adopted for a finer layout. The proposed approach saves much CPU time through a two-stage approach scheme, while other annealing-based algorithm so far reported fur a nesting problem are computationally expensive. The proposed nesting approach uses the stochastic process, and has a much higher possibility to obtain a global solution than the deterministic searching technique. We developed the automatic nesting software of NST(ver.1.1) software for footwear industry by implementing of these proposed algorithms. The NST software was applied by the optimized automatic arrangement algorithm to cut without the loss of leathers. if possible, after detecting damage areas. Also, NST software can consider about several features in not only natural loathers but artificial ones. Lastly, the NST software can reduce a required time to implement generation of NC code. cutting time, and waste of raw materials because the NST software automatically performs parts arrangement, cutting paths generation and finally NC code generation, which are needed much effect and time to generate them manually.

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An Efficient Decoy File Placement Method for Detecting Ransomware (랜섬웨어 탐지를 위한 효율적인 미끼 파일 배치 방법)

  • Lee, Jinwoo;Kim, Yongmin;Lee, Jeonghwan;Hong, Jiman
    • Smart Media Journal
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    • v.8 no.1
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    • pp.27-34
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    • 2019
  • Ransomware is a malicious program code evolved into various forms of attack. Unlike traditional Ransomware that is being spread out using email attachments or infected websites, a new type of Ransomware, such as WannaCryptor, may corrupt files just for being connected to the Internet. Due to global Ransomware damage, there are many studies conducted to detect and defense Ransomware. However, existing research on Ransomware detection only uses Ransomware signature database or monitors specific behavior of process. Additionally, existing Ransomware detection methods hardly detect and defense a new Ransomware that behaves differently from the traditional ones. In this paper, we propose a method to detect Ransomware by arranging decoy files and analyzing the method how Ransomware accesses and operates files in the file system. Also, we conduct experiments using proposed method and provide the results of detection and defense of Ransomware in this paper.

A Study on the Land-Use Related Assessment Factors in Korean Environmental Impact Assessment (환경영향평가 토지환경 분야의 토지이용 평가항목 고찰 연구)

  • Park, Sang-Jin;Lee, Dong Kun;Jeong, Seulgi
    • Journal of Environmental Impact Assessment
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    • v.30 no.5
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    • pp.297-304
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    • 2021
  • The environmental impact assessment(EIA) project in Korea has undergone changes and revisions in various evaluation items for about 30 years after the introduction of the Environmental Conservation Act (1997). However, despite the importance of land use evaluation items under the current EIA Act, there are insufficient studies to consider. Therefore, this study focused on the land-use evaluation items based on the EIA guidelines, reviewed 90 of the evaluation documents and consultation documents, and tried to suggest implications and supplementary points forthe domestic EIA land-use evaluation items. As a result, the paradigm was changing from land efficiency centered on development in the past to land efficiency centered on the natural environment and resource conservation. However, in spite of the manual for fitting the paradigm change, opinions on the conservation of the natural environment are still being drawn in the consultation document, so it needs improvement. Two improvements in the impact assessment process suggested in this study are the establishment of standardized spatial data and a quantitative impact and reduction method evaluation tool based on it. In particular, there is a need for a plan evaluation tool for land use arrangement and distribution that can solve the needs of minimizing damage to the natural environment and securing green space and a green network.

A Study on Quantitative Risk Analysis & Model Application for Hydrogen Filling Center (수소충전시설에 대한 정량적 위험성 평가 및 모델적용에 관한 연구)

  • Shin, Jung-Soo;Byun, Hun-Soo
    • Journal of the Korean Institute of Gas
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    • v.16 no.6
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    • pp.87-101
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    • 2012
  • In gas industries, the potential risks of serious accidents have been increased due to high technology application and process complexities. Especially, in case of gas-related accidents, the extent of demage is out of control since gas plants handle and produce combustible, flammable, explosive and toxic materials in large amounts. The characteristics of this kind of disaster is that accident frequency is low, while the impact of damage is high, extending to the neighboring residents, environment and related industries as well as employees involved. The hydrogen gases treated important things and it used the basic material of chemical plants and industries. Since 2000, this gas stood in the spotlight the substitution energy for reduction of the global warming in particular however it need to compress high pressure(more than 150 bar.g) and store by using the special cylinders due to their low molecular weight. And this gas led to many times the fire and explosion due to leak of it. To reduce these kinds of risks and accidents, it is necessary to improve the new safety management system through a risk management after technically evaluating potential hazards in this process. This study is to carry out the quantitative risk assesment for hydrogen filling plant which are very dangerous(fire and explosive) and using a basic materials of general industries. As a results of this risk assessment, identified the elements important for safety(EIS) and suggested the practical management tools and verified the reliability of this risk assessment model through case study of accident.

Information Technologies in the Formation of Environmental Consciousness in Future Professionals

  • Tomchuk, Mykhailo;Khrolenko, Maryna;Volokhata, Kateryna;Bakka, Yuliia;Ieresko, Oleg;Kambalova, Yanina
    • International Journal of Computer Science & Network Security
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    • v.22 no.1
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    • pp.331-339
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    • 2022
  • The global process of transition from industrial to information society, as well as socio-economic changes taking place in Ukraine, require significant changes in many areas of state activity. It is especially connected with the reforms in the sphere of education. Today, national programs provide for the development of education on the basis of new progressive concepts, the introduction of the educational process of new pedagogical technologies and scientific achievements, the creation of a new system of information education, entrance of Ukaine into the transcontinental computer information system. Information technologies are qualitatively changing the key resources of development: this is no longer a space with fixed production, but primarily mobile finance and intelligence. They have a direct impact on the formation of personal growth, professional content and self-organization, emotional and psychological maturity and consciousness, and so on. One of the main factors in ensuring the stability and social education of the country's citizens is the culture of security, the formation and development of which is an urgent problem today. Comprehensive and systematic development of security culture will significantly increase the readiness of the population, the level of environmental, labor and patriotic education, reduce human losses, material damage from emergencies. Ecological education can be carried out more successfully only gradually and in accordance with the socio-psychological periods of one's development: kindergarten - school - college - university. The creation of such a system of environmental education should be enshrined as the basis of state environmental policy as a constitutional norm with the usage of information technology. Graduates of universities, who are the future of our country, after mastering the skills of basic environmental education must have a high level of environmental culture, which is, in turn, part of general human culture, and investigate environmental issues from the standpoint of their profession. It is known that with the help of environmental education the collective intelligence of society is formed, which can predict human activities and processes occurring in nature, and in some way to help with the elimination of crises. It is through environmental education that another system of human values is being formed, which places great emphasis on intangible wealth and solidarity, and great responsibility of humanity for the ecological state of the native country; provides a higher standard of living as a result of sustainable development, through the introduction of information technology in this system. To improve the quality of life, we need better knowledge, which must be implemented through information technology at the international level.

Fabrication of Electrospun Composite Membranes with Silk Powder (실크 입자가 도입된 전기방사 복합막 제조)

  • Seo, Young Jin;Kang, Hoseong;Im, Kwang Seop;Choi, Kang-min;Park, Chi Hoon;Nam, Sang Yong;Jang, Hae Nam
    • Membrane Journal
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    • v.32 no.2
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    • pp.133-139
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    • 2022
  • As the issue of reducing greenhouse gases is emerging due to global warming and extreme weather, research on materials capable of radiative cooling without energy consumption is being actively conducted. Among them, silk is known as a natural self-cooling material, but in the conventional mixing process using chemically powdered silk, there is a problem that the radiative cooling effect disappears by the collapses of the intrinsic crystal structure of silk fibroin, so it is difficult to manufacture it in the form of a film or coating agent for radiative cooling. In this study, various types of membranes were manufactured using silk powder that went through a physical pulverization process that does not damage the intrinsic structure of silk fibroin, and the study was conducted to examine its applicability as a coating agent. Electrospun membranes and flat sheet membranes were prepared by using silk fibroin powder for this purpose, and it was observed that the viscosity of the solution had a significant effect on the membrane fabrication and its properties.

Aviation Safety Regulation and ICAO's Response to Emerging Issues (항공안전규제와 새로운 이슈에 대한 ICAO의 대응)

  • Shin, Dong-Chun
    • The Korean Journal of Air & Space Law and Policy
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    • v.30 no.1
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    • pp.207-244
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    • 2015
  • Aviation safety is the stage in which the risk of harm to persons or of property damage is reduced to, and maintained at or below, an acceptable level through a continuing process of hazard identification and risk management. Many accidents and incidents have been taking place since 2014, while there had been relatively safer skies before 2014. International civil aviation community has been exerting great efforts to deal with these emerging issues, thus enhancing and ensuring safety throughout the world over the years. The Preamble of the Chicago Convention emphasizes safety and order of international air transport, and so many Articles in the Convention are related to the safety. Furthermore, most of the Annexes to the Convention are International Standards and Recommended Practices pertaining to the safety. In particular, Annex 19, which was promulgated in Nov. 2013, dealing with safety management system. ICAO, as law-making body, has Air Navigation Commission, Council, Assembly to deliberate and make decisions regarding safety issues. It is also implementing USOAP and USAP to supervise safety functions of member States. After MH 370 disappeared in 2014, ICAO is developing Global Tracking System whereby there should be no loophole in tracking the location of aircraft anywhere in world with the information provided by many stakeholders concerned. MH 17 accident drove ICAO to install web-based repository where information relating to the operation in conflict zones is provided and shared. In addition, ICAO has been initiating various solutions to emerging issues such as ebola outbreak and operation under extreme meteorological conditions. Considering the necessity of protection and sharing of safety data and information to enhance safety level, ICAO is now suggesting enhanced provisions to do so, and getting feedback from member States. It has been observed that ICAO has been approaching issues towards problem-solving from four different dimensions. First regarding time, it analyses past experiences and best practices, and make solutions in short, mid and long terms. Second, from space perspective, ICAO covers States, region and the world as a whole. Third, regarding stakeholders it consults with and hear from as many entities as it could, including airlines, airports, community, consumers, manufacturers, air traffic control centers, air navigation service providers, industry and insurers. Last not but least, in terms of regulatory changes, it identifies best practices, guidance materials and provisions which could become standards and recommended practices.

The Current Status of Domestic Marine Salvage Industry and Measures for its Promotion (국내 해양 구난산업의 현황과 육성방안에 관한 연구)

  • An, Kwang;Jeong, Jung-Sik;Kim, In-Chul;Kim, Deuk-Bong
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.26 no.2
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    • pp.149-155
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    • 2020
  • Since marine accidents cause large-scale damage to human lives and the marine environment, prompt response measures are crucial including salvage operations for ships and cargoes along with lifesaving operations. In Korea, marine salvage operations are mainly dependent on global salvage companies in case of large-scale marine accidents due to lack of national capacity for marine salvage. The purpose of this study was to suggest public measures for the promotion of the private salvage industry by identifying the current situation and problems in the domestic marine salvage industry. As a result of the study, the measures of setting up a dedicated agency to support the domestic salvage industry and the function of the dedicated agency were identified and presented. In addition, the main points of the bill of "Law on the Promotion of the Domestic Salvage Industry" were presented to support and promote the salvage industry. To prepare the draft bill of law, relevant domestic laws and international conventions were examined to define the terms and regulations. Based on the legislation enacted as a result of this study, relevant ministries should focus on the legislative process. Legislation can be pursued by competent ministries in cooperation with the private sector and academia. It is expected that this study will help in the development of the domestic marine salvage industry and enhance the national response capacity for marine accidents in Korea.