• 제목/요약/키워드: geo-body

검색결과 63건 처리시간 0.032초

Protection against Whole Body γ-Irradiation Induced Oxidative Stress and Clastogenic Damage in Mice by Ginger Essential Oil

  • Jeena, Kottarapat;Liju, Vijayasteltar B;Ramanath, Viswanathan;Kuttan, Ramadasan
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권3호
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    • pp.1325-1332
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    • 2016
  • Radioprotective effects of ginger essential oil (GEO) on mortality, body weight alteration, hematological parameters, antioxidant status and chromosomal damage were studied in irradiated mice. Regression analysis of survival data in mice exposed to radiation yielded LD50/30 as 7.12 and 10.14 Gy for control (irradiation alone) and experimental (GEO-treated irradiated) mice, respectively, with a dose reduction factor (DRF) of 1.42. In mice exposed to whole-body gamma-irradiation (6 Gy), GEO pre-treatment at 100 and 500 mg/kg b.wt (orally) significantly ameliorated decreased hematological and immunological parameters. Radiation induced reduction in intestinal tissue antioxidant enzyme levels such as superoxide dismutase, catalase, glutathione peroxidase and glutathione was also reversed following administration of GEO. Tissue architecture of small intestine which was damaged following irradiation was improved upon administration of GEO. Anticlastogenic effects of GEO were studied by micronuclei assay, chromosomal aberration and alkaline gel electrophoresis assay. GEO significantly decreased the formation of micronuclei, increased the P/N ratio, inhibited the formation of chromosomal aberrations and protected agaisnt cellular DNA damage in bone marrow cells as revealed by comet assay. These results are supportive of use of GEO as a potential radioprotective compound.

SMTCR 모델을 이용한 지질자원기술 연구성과 커뮤니케이션 방안 연구 (A Study on Communication Programs of Geo-Technology R&D Outcome Using the SMTCR Model)

  • 김찬석;김성용
    • 자원환경지질
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    • 제41권2호
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    • pp.267-273
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    • 2008
  • 본 연구는 지질자원기술 연구성과에 대한 커뮤니케이션 방안을 도출하고자 수행하였다. 이를 위해 본 연구는 다음과 같은 연구문제를 설정하였다. 1) 주요 일간신문에 지질자원기술의 연구주체에 대한 보도가 차지하는 비중은 어느 정도인가? 2) 지질자원기술 연구성과의 커뮤니케이션 상의 강점과 약점, 위기요인과 기회요인은 무엇인가? 3) 지질자원기술 연구성과 커뮤니케이션 과제와 이를 수행하기 위한 커뮤니케이션 방안은 무엇인가? 본 연구에서는 SMTCR (송신자-메시지-도구-경로-수신자의 유기적 관계)모델을 이용한 지질자원기술 연구성과의 커뮤니케이션 방안을 제시하였다.

맥진(脈診)과 '유(痏)'를 중심으로 한 무자법(繆刺法)연구 (Study of Mu-acupuncture Treatment Focusing to the Pulse Diagnosis and 'Yu')

  • 지재동;김광중
    • 동의생리병리학회지
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    • 제25권5호
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    • pp.790-798
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    • 2011
  • 'Mu-acupuncture treatment(繆刺法)' and 'Geo-acupuncture treatment(巨刺法)' are the ways of taking acupuncture points on the sound side of a human body and not on the unsound side of a human body to treat disease, 'Mu-acupuncture treatment(繆刺法)' is applicable to 'Transverse meridian disease(絡脈病)', 'Geo-acupuncture treatment(巨刺法)' is applicable to 'Longitudinal meridian disease(經脈病)'. To diagnose a disease as transverse meridian disease or longitudinal meridian disease depends on 'Feeling pulse at the nine spots of three parts on a body for diagnosis (三部九候診)'. 'Mu-acupuncture treatment(繆刺法)' takes a 'Rak-acupuncture point(絡穴)' under a wrist and a ankle joint. The method of taking it, two ways, are 'Yu(痏)' and 'The treatment getting some blood(出血療法)'. 'Yu(?)' which is similar to 'Quick-getting acupuncture into and out (單刺法)' means the number of times doing acupuncture and is different from 'The treatment getting some blood (出血療法)' which is typically considered as 'Yu(?)'. Meanwhile, judging from the changes of the methods of feeling pulse for diagnosis and the symptoms of a certain disease, though it is a precondition that 'Biased-Gi(邪氣)' stays at 'The Large transverse meridian(大絡)' in 'The theory of Mu-acupuncture treatment(繆刺論)', it is hard to consider the symptoms of 'Transverse meridian disease(絡脈病)' described in 'The theory of Mu-acupuncture treatment(繆刺論)' as the pure symptoms of 'Transverse meridian disease(絡脈病)'.

조선시대 무속복식연구-좌당 내력을 중심으로- (A Study on the Apparels of Shamanism during Cho Sun Dynasty)

  • 조효순
    • 복식
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    • 제34권
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    • pp.195-208
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    • 1997
  • 1) The color of JOGORI and CHIMA was such gorgeous and those garments were put on during the events of GAM-EUNG-CHUNG-BAI HO-GU-GEO-RI JO-SANG-GEO-RI DEWT-JUN and CHAN-BOO-GEO-RI. 2)BULSA-JANG-SAM(JE-SUK-GEO-RI) was white colored and had wide sleeves putting on a pink priestrobe and a pink belt on it 3) they put on HONG-CHUL-NIK(GU-REUNG) and CHONG-CHUL-NIK(DAE-GEO-RI). 4)They put on GOO-GUN-BOK(JUN-RIP JUN-BOK(BYUL-SUNG-GEO-RI) DONG-DA-RI(Expel the demon) 5) MONG-DOO-RI(MAN-SIN-MAL-BYUNG) put on the garment constructed with the color and from of a white straight collar a wide sleeve and a pink belt 6) A long robe was colored with green (GAM-EUNG-CHUNG-BAI) and was used not as a headdress but as a man's overcoat. 7) CHANG-EUI was a green colored small CHAHG-EUI(SUNG-JO-GEO-RI). As observed above the Shaman apprel during Chosun Dynasty is a part of the traditional clothing originated from THE THEORY OF THE COSMIC DUAL FORCES and THEORY OF THE COSMIC DUAL FORCES and the FIVE ELEMENTS (i.e. metal wood water fire and earth) It's basic form and wearing method were not so different from the traditional clothing silmilar to the official uniform during Chosun Dynasty and the official uniform was the symbol of authority(almost almighty) at that time of period and to that the Shaman apparel was constructed with the more gorgeous colors to emphasize the sanctity or the descent of the Divine Being from heaven. We realized that a Shaman had put on the symbolic garment suitable for the grade and nature of the Divine Body at every events to enter into " The World of Gods"Gods."

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증고에 따른 기존 CFRD 댐체의 변형거동 (Deformation Behavior of Existing Concrete-Faced Rockfill Dam due to Raising)

  • 신동훈;조성은;전제성;이종욱
    • 한국지반환경공학회 논문집
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    • 제8권6호
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    • pp.77-83
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    • 2007
  • 본 논문에서는 이미 사용 중인 콘크리트표면차수벽형석괴댐(이하 CFRD)에 대하여 저수용량 확대 또는 수리 수문학적 안정성을 증대할 목적 등으로 하류측에 추가 축조하여 댐의 높이를 높이는 경우에 대하여 추가 축조과정에 기존 댐체 및 추가 축조 부분의 변형거동을 유한요소해석법으로 검토하였다. 해석결과 기존 댐체의 하류측에 덧붙여 추가 축조할 경우 기존 댐체 전반에 걸쳐 추가 변형이 발생하는 것으로 나타났다. 특히, 상류사면은 침하(댐마루측)와 융기(댐체 하부측)가 동시에 발생하며, 이 경우CFRD의 특성상 상류사면에 시공되어 있는 콘크리트 차수벽에는 휨모멘트에 의한 인장균열이 발생할 수 있는 것으로 나타났다. 따라서 기존 CFRD에 증고를 하는 경우에는 시공전에 반드시 기존 차수벽의 변형량과 휨모멘트 발생량 등을 검토하고 경우에 따라서는 적절한 보완대책의 수립이 필요한 것으로 나타났다.

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3차원 수치해석에 의한 필 댐의 누수량 평가 (Seepage Quantity Evaluation of a Fill Dam using 3D FEM Analysis)

  • 최병일
    • 한국지반환경공학회 논문집
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    • 제16권8호
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    • pp.45-49
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    • 2015
  • 침투에 대한 안정성 평가 시 댐체의 가장 큰 단면을 반영해 2차원으로 수치해석을 실시하는 것이 일반적이며, 해석결과를 이용한 침투수량 평가 시 댐체 하부지반을 단순한 직사각형 형태로 가정하여 침투수량을 구한 후 단면형상을 반영해 최종 침투수량을 계산하고 있다. 하지만 최근 기술의 발달로 댐 시공 시 다양한 형태의 지반 위에 다양한 형태의 댐들이 축조되고 있는 점을 감안하면 3차원 수치해석을 통해 댐체의 형상 및 지형조건을 보다 정확하게 반영한 결과를 이용하여 결론을 도출하는 것이 바람직하다고 판단된다. 따라서 본 연구에서는 3차원 FEM 수치해석법을 이용하여 강우량을 포함한 다른 기타요인은 배제한 후 댐체로만 통과되는 침투수량 평가를 통해 안전관리를 할 수 있는 방안을 제시하고자 한다.

DCM 설계에서 주요 인자의 결정과 내.외적 안정해석 (The Analysis of Internal & External Stabilities and Factors for D.C.M Design)

  • 이충호;정승용;한상재
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2009년도 세계 도시지반공학 심포지엄
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    • pp.793-808
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    • 2009
  • This paper presents procedure and prediction method of internal and external stabilities when designing D.C.M, with main factors to be considered, such as chemical reaction of additive, physical properties of stabilized body and mixing strength. Results show that through case studies, a design unconfined compressive strength of stabilized body (hereafter referred to as 'compressive strength') directly depends on the quantity of cement, which is decided by laboratory test, and the compressive strength enormously affects internal and external stabilities. So laboratory mixing test to obtain the compressive strength for design allowable stress should be given careful considerations.

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천연식물자원으로부터 Acetylcholine esterase 저해 활성 탐색 및 인지기능에 미치는 영향 (Screeening of Natural Plant Resources with Acetylcholine esterase inhibitory activity and Effect on Scopolamine-induced Memory Impairment)

  • 최장원;원무호;주한승
    • 농업생명과학연구
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    • 제45권6호
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    • pp.213-226
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    • 2011
  • 아세틸콜린 분해효소(acetylcholine esterase, AChE) 억제제는 아세틸콜린 함량을 높여 콜린성 neuron을 활성화함으로써 기억 능력의 개선 및 치매 개선을 가져와 현재 다양한 AChE 억제제들이 개발되어 사용되고 있다. 본 연구에서는 AChE에 대한 억제 활성을 갖는 천연물을 다양한 식물추출물 및 에센스오일로부터 탐색하였으며, 탐색한 추출물의 scopolamine으로 기억손상을 유발한 쥐의 기억력 개선 활성을 치매 치료제로 사용하고 있는 donepizil과 비교 분석하였다. 그 결과 자몽(Citrus paradisi) 유래의 에센스 오일이 AChE 억제 활성이 가장 높아 20 ug/ml의 농도로 처리하였을 때 90% 이상의 효소 억제 활성을 나타내었다. 수동회피 실험 결과, 자몽 유래의 에센스오일(100 mg/kg, p.o.)을 투여한 쥐는 치매 치료제로 사용하고 있는 donepizile (0.5 mg/kg)을 투여한 쥐와 유사한 latency time을 나타내어 인지기능이 개선되었다. 또한, 수중미로 시험 결과, 자몽 유래 에센스오일(100 mg/Kg, p.o.)을 투여한 쥐는 donepizile(0.5 mg/kg)을 투여한 쥐와 유사한 latency time을 나타내어 인지기능이 개선되었다. 이상의 결과로부터 자몽 유래 에센스오일은 매우 효과적으로 기억력을 개선하여 인지기능을 개선해 줄 수 있는 안전하고 효과적인 후보물질이라고 사료된다.

이중맹검용 피내침을 이용한 단순성 비만여성의 사암침 치료효과에 관한 임상선행연구 (A Pilot Study of Sa-am Acupuncture Treatment Used by Sham Acupuncture for the Simple Obesity)

  • 김성철;장은하;나원민;이성용;이종덕;문형철;최선미;정영해
    • Journal of Acupuncture Research
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    • 제24권5호
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    • pp.67-88
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    • 2007
  • Objectives : To present proper protocol as global standard- clinical study about acupuncture treatment, and to demonstrate effectiveness of Sa-am Acupuncture treatment for obesity. Methods : We randomly allocated participants to treatment group 1 and 2. The group 1 is treated by real acupuncture and the group 2 is treated by Kim Sham Acupuncture. We treated Bi-jang seung-gyeok (脾臟勝格) ; Daedon(LR1), EunBaek(SP1) Gyoung-geo(LU8) Sang-gu(SP5), to both group. Primary outcomes were measured by the Body Composition Analysis(Inbody. Korea). Secondary outcomes were measured by Blood Cholesterol, Triglyceride, HDL, LDL Cholesterol. Results : After treatment, the group 1 shown significant weight loss that analysed by Kruskal-Wallis certification, but didn't show notable change in body fat, total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol. Group 2 didn't show significant change in body weight, body fat, triglyceride, HDL cholesterol, LDL cholesterol, but total cholesterol was notably decreased. Controled group was not changed in body weight, body fat. Aftter treatment, 3 groups didn't show significant change in body weight, body fat, triglyceride, HDL cholesterol, LDL cholesterol, total cholesterol.

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댐 제체 및 침투수 흐름의 지열학적 고찰 (A Study on Geothermal Characteristics of Dam Body and Seepage Flow)

  • 박동순;정우성;김형수
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2006년도 춘계 학술발표회 논문집
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    • pp.75-85
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    • 2006
  • In recent geotechnical engineering, geothermal approach has been on the horizon to deal with geoenvironmental issues, freezing and thawing problems, and seepage phenomenon in dams and embankments. In this study, geothermal characteristic through inner body of dams and its influence on the seepage flow were experimented by lab test and field instrumentation. Also, one of up-to-date temperature monitoring technique, called as multi-channel thermal line sensing, was evaluated its availability. As a result of lab test, it is found that the seepage flow has influence on the geothermal characteristic and a potential of finding phreatic line and seepage fluctuation could be possible by continuous temperature monitoring using thermal line sensing skills. These kine of geothermal information could be available to the modelling of water geo-structure interaction. Out of short-term field tests, clear water table and temperature distribution of a dam were easily found through temperature monitoring in holes located near a reservoir and holes within a depth of constant temperature layer. However, it is also found that the geothermal flow and finding seepage line could not be easily understandable through multi-channel temperature monitoring because of the existence of constant temperature field, thermal conductivity of soils and rocks, and unsaturated characteristics of geo-material. In this case, long-term geothermal monitoring is recommended to find sudden fluctuation of seepage line and amount of leakage.

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