• Structural Monitoring and Maintenance
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• v.9 no.4
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• pp.323-336
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• 2022

Steel truss bridge is one of the most widely used bridge types in Indonesia. Out of all Indonesia's national roads, the number of steel truss bridges reaches 12% of the total 17,160 bridges. The application of steel truss bridges is relatively high considering this type of bridge provides advantages in the standardization of design and fabrication of structural elements for typical bridge spans, as well as ease of mobilization. Directorate of Road and Bridge Engineering, Ministry of Works and Housing, has issued a standard design for steel truss bridges commonly used in Indonesia, which is designed against the design load in SNI 1725-2016 Bridge Loading Standards. Along with the development of actual traffic load measurement technology using Bridge Weigh-in-Motion (B-WIM), traffic loading data can be utilized to evaluate the reliability of standard bridges, such as standard steel truss bridges which are commonly used in Indonesia. The result of the B-WIM measurement on the Central Java Pantura National Road, Batang - Kendal undertaken in 2018, which supports the heaviest load and traffic conditions on the national road, is used in this study. In this study, simulation of a sequences of traffic was carried out based on B-WIM data as a moving load on the Australian type Steel Truss Bridge (i.e., Rangka Baja Australia -RBA) structure model with 60 m class A span. The reliability evaluation was then carried out by calculating the reliability index or the probability of structural failure. Based on the analysis conducted in this study, it was found that the reliability index of the 60 m class Aspan for RBA bridge is 3.04 or the probability of structural failure is 1.18 × 10^-3, which describes the level of reliability of the RBA bridge structure due to the loads from B-WIM measurement in Indonesia. For this RBA Bridge 60 m span class A, it was found that the calibrated nominal live load that met the target reliability is increased by 13% than stated in the code, so the uniform distributed load will be 7.60 kN/m² and the axle line equivalent load will be 55.15 kN/m.

• IMMUNE NETWORK
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• v.4 no.3
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• pp.131-142
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• 2004

In recent years, adjuvants have received much attention because of the development of purified subunit and synthetic vaccines which are poor immunogens and require adjuvants to evoke the immune response. Therefore, immunologic adjuvants have been developed and testing for most of this century. During the last years much progress has been made on development, isolation and chemical synthesis of alternative adjuvants such as derivatives of muramyl dipeptide, monophosphoryl lipid A, liposomes, QS-21, MF-59 and immunostimulating complexes (ISCOMS). Biodegradable polymer microspheres are being evaluated for targeting antigens on mucosal surfaces and for controlled release of vaccines with an aim to reduce the number of doses required for primary immunization. The most common adjuvants for human use today are aluminum hydroxide and aluminum phosphate. Calcium phosphate and oil emulsions have been also used in human vaccination. The biggest issue with the use of adjuvants for human vaccines is the toxicity and adverse side effects of most of the adjuvant formulations. Other problems with the development of adjuvants include restricted adjuvanticity of certain formulations to a few antigens, use of aluminum adjuvants as reference adjuvant preparations under suboptimal conditions, non-availability of reliable animal models, use of non-standard assays and biological differences between animal models and humans leading to the failure of promising formulations to show adjuvanticity in clinical trials. The availability of hundreds of different adjuvants has prompted a need for identifying rational standards for selection of adjuvant formulations based on safety and sound immunological principles for human vaccines. The aim of the present review is to put the recent findings into a broader perspective to facilitate the application of these adjuvants in general and experimental vaccinology.

• The Journal of the Korea Contents Association
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• v.9 no.12
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• pp.600-612
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• 2009

Special banks primarily using Internet have different properties in transactions with customers, risk management, capital strength, and branch networks with general banks. The success and failure factors of Internet banks have been explained only by the economies of scale, and learning and experience effects of Internet banks based on the perspective of organizational ecologies. In this study, the success factors of Internet banks are investigated based on strategic choice by organizations and resource-based view of the firms instead of organizational ecology perspective. To this end, 31 major Internet banks operating in overseas market have been classified by the size and profitability of banks, and three strategic groups have been derived. three representative company cases were analyzed. critical success factors of Internet banks were derived, and considerable points when operating Internet banks were discussed.

• Journal of the Korean Operations Research and Management Science Society
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• v.22 no.3
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• pp.209-222
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• 1997

In this paper, we study a bargaining order problem where one buyer sequentially bargains with two sellers whose reservation prices are unknown to the buyer but correlated. Our main question is who the buyer should bargain first with to maximize his expected payoff. This type of problem is widely applicable to business and political situations where one party negotiates with multiple parties sequentially. One of the most important element in a sequential bargaining is "linkage effect" which exists when the aggreement of the previous bargaining affects the outcome of the following bargaining. To examine "linkage effect", we assume that the sellers'objects are similar so that the sellers' reservation prices are correlated. In addition, to consider incomplete information aspect regarding reservation prices, it is assumed that the sellers' reservation prices are unknown to the buyer. That is, we deal with one sided incomplete information case. In our model, there are two stages in each of which the buyer meets one seller. Since we are concerned with the bargaining order, we consider two different bargaining orders. Using game theory, we find a perfect Bayesian equilibrium and compute the buyer's expected payoff for each bargaining order. Finally we identify the advantageous bargaining order for the buyer by comparing the expected payoffs obtained under two different bargaining orders. Our results are as follows: the advantageous bargaining order depends on the prior probability of the seller type. However, in general, the buyer should bargain first with the seller whose object is less valuable to the buyer. The basic reason for our result is that the buyer wants to experiment in the first stage to find out the sellers' reservation prices and in doing so, to minimize the experimental cost and maximize potential gain in case of negotiation failure in the first stage. in the first stage.

• Advances in concrete construction
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• v.6 no.3
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• pp.245-268
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• 2018

The numerical investigations have been carried out on deep beam with opening subjected to static monotonic loading to demonstrate the accuracy and effectiveness of the finite element based numerical models. The simulations were carried out through finite element program ABAQUS/CAE and the results thus obtained were validated with the experiments available in literature. Six simply supported beams were modelled with two square openings of 200 and 250 mm sides considered as opening at centre, top and bottom of the beam. In order to define the material behaviour of concrete and reinforcing steel bar the Concrete Damaged Plasticity model and Johnson-Cook material parameters available in literature were employed. The numerical results were compared with the experiments in terms of ultimate failure load, displacement and von-Mises stresses. In addition to that, seventeen beams were simulated under static loading for studying the effect of opening location, size and shape of the opening and depth, span and shear span to depth ratio of the deep beam. In general, the numerical results accurately predicted the pattern of deformation and displacement and found in good agreement with the experiments. It was concluded that the structural response of deep beam was primarily dependent on the degree of interruption of the natural load path. An increase in opening size from 200 to 250 mm size resulted in an average shear strength reduction of 35%. The deep beams having circular openings undergo lesser deflection and thus they are preferable than square openings. An increase in depth from 500 mm to 550 mm resulted in 78% reduced deflection.

• The KIPS Transactions:PartD
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• v.14D no.3 s.113
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• pp.303-310
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• 2007

Information system failure is various such as program test unpreparedness, physical facilities for damage prevention unpreparedness from simple software error. Although cross is trifling the result causes vast damage. Recently, became difficult by simple outside security system to solve this problem. Now, synthetic countermove establishment and suitable confrontation connected with danger came in necessary visual point about general Information Technology of enterprise. In connection with, in this paper, various informations and system and control about data that can happen information inside and outside considering integrity for IT resource, solubility, confidentiality within organization studied about special quality to model synthetic Risk Management System that can of course and cope in danger.

• Computational Structural Engineering
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• v.10 no.3
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• pp.241-250
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• 1997

The strain localization of concrete is a phenomenon such that the deformation of concrete is localized in finite region along with softening behavior. The objective of this paper is to develop a plasticity and damage algorithm for the finite element analysis of the strain-localization in concrete. In this paper, concrete member under strain localization is modeled with localized zone and non-localized zone. For modeling of the localized zone in concrete under strain localization, a general Drucker-Prager failure criterion by which the nonlinear strain softening behavior of concrete after peak-stress can be considered is introduced in a thermodynamic formulation of the classical plasticity model. The return-mapping algorithm is used for the integration of the elasto-plastic rate equation and the consistent tangent modulus is also derived. For the modeling of non-localized zone in concrete under strain localization, a consistent nonlinear elastic-damage algorithm is developed by modifying the free energy in thermodynamics. Using finite element program implemented with the developed algorithm, strain localization behaviors for concrete specimens under compression are simulated.

• Journal of KIISE:Computing Practices and Letters
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• v.9 no.5
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• pp.498-508
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• 2003

In the field of finance, Trading System of Securities is a very vulnerable application when it faces any small problems just for one minute. Since Trading System changes its environment from mainframes to client/server, its safety becomes the most important factor. Even though most If systems are configured by general guidelines currently, Trading System is an exception that it is configured by specific and rather ad hoc guidelines in order to ensure its safe management. In this thesis, I will prove the validity of specific and ad hoc configuration in the environment of Trading Systems where I use both XA interface system and Non-XA interface to configure its system based on 3-Tier Client/server computing environment through middleware, TP-Monitor, in the X/Open DTP Model. In order to validate the Trading System, I will compare and analyze the error of data of an order and ability to restore using both XA and Non-XA interfaces while testing take-over scenario on the assumption of the system's failure.

• Herbal Formula Science
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• v.17 no.2
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• pp.123-132
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• 2009

Acetaminophen (AP) is widely used as an over-the-counter analgesic and antipyretic drug. AP-induced hepatotoxicity is a common consequence of AP overdose and may lead to acute liver failure. In this study, we investigated the liver damage in mice using single dose (300 mg/kg) of AP and the possible protective effects of administration (50-200 mg/kg body weight) of Joo-Juk on acetaminophen-induced liver damage in mice. The alanine aminotransferase (ALT), and aspartate aminotransferase (AST) activities were determined in the plasma of mice. The effect of Joo-Juk on lipid peroxidation product thiobarbituric reacting substances (TBARS) and some antioxidant enzymes superoxide dismutase (SOD), catalase, d-aminolevulinate dehydratase ($\sigma$-ALA-D) activities, and gluthathione peroxidase (GPx), were also evaluated in the mouse liver homogenate. AP caused liver damage as evident by statistically significant increased in plasma activities of AST and ALT. There were statistically significant losses in the activities of SOD, catalase, $\sigma$-ALA-D, and GPx and an increase in TBARS in the liver of AP-treated group compared with the control group. However, Joo-Juk was able to counteract these effects. These results suggest that Joo-juk can act as hepato-protectant against AP toxicity and is a good candidate for further evaluation as an effective chemotherapeutic agent.

• Nuclear Engineering and Technology
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• v.45 no.2
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• pp.151-164
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• 2013

A key input for the assessment of Human Error Probabilities (HEPs) with Human Reliability Analysis (HRA) methods is the evaluation of the factors influencing the human performance (often referred to as Performance Shaping Factors, PSFs). In general, the definition of these factors and the supporting guidance are such that their evaluation involves significant subjectivity. This affects the repeatability of HRA results as well as the collection of HRA data for model construction and verification. In this context, the present paper considers the TAsk COMplexity (TACOM) measure, developed by one of the authors to quantify the complexity of procedure-guided tasks (by the operating crew of nuclear power plants in emergency situations), and evaluates its use to represent (objectively and quantitatively) task complexity issues relevant to HRA methods. In particular, TACOM scores are calculated for five Human Failure Events (HFEs) for which empirical evidence on the HEPs (albeit with large uncertainty) and influencing factors are available - from the International HRA Empirical Study. The empirical evaluation has shown promising results. The TACOM score increases as the empirical HEP of the selected HFEs increases. Except for one case, TACOM scores are well distinguished if related to different difficulty categories (e.g., "easy" vs. "somewhat difficult"), while values corresponding to tasks within the same category are very close. Despite some important limitations related to the small number of HFEs investigated and the large uncertainty in their HEPs, this paper presents one of few attempts to empirically study the effect of a performance shaping factor on the human error probability. This type of study is important to enhance the empirical basis of HRA methods, to make sure that 1) the definitions of the PSFs cover the influences important for HRA (i.e., influencing the error probability), and 2) the quantitative relationships among PSFs and error probability are adequately represented.