• Title/Summary/Keyword: gel materials

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Influence of pH and Dye Concentration on the Physical Properties and Microstructure of New Coumarin 4 Doped SiO2-PDMS ORMOSIL

  • Oh, E.O.;Gupta, R.K.;Cho, N.H.;Yoo, Y.C.;Cho, W.S.;Whang, C.M.
    • Bulletin of the Korean Chemical Society
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    • v.24 no.3
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    • pp.299-305
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    • 2003
  • Physical properties and microstructure of new coumarin 4 doped $SiO_2$-PDMS ORMOSILs, synthesized by one-step (OS, acid-catalysis) and two-step (TS, acid-base catalysis) routes of sol-gel method with varying pH (0.6 to 7) and dye content $(5\;{times}\;10^{-4}\;to\;5{\times}\;10^{-2}\;mole)$, are reported. BET, UV-visible spectroscopy and SEM were used for characterizations. The increase in acid or base concentration increased the size of pores and aggregated silica particles. The samples with pH ≤ 2.5 were transparent and attributed to the small size of pores (~20 Å) and silica particles. The samples with pH > 2.5 were translucent or opaque due to non-uniform pore system formed by voids and large aggregated silica particles. The surface area was found a key factor controlling the interactions between the gel matrix and the dye. The OS samples with the highest dye concentration exhibited the minimal values of pore size, surface area and silica particle size, resulting in the concentration-quenching phenomenon.

Biomedical Applications of Silk Protein

  • Kweon, Hae-Yong;Cho, Chong-Su
    • International Journal of Industrial Entomology and Biomaterials
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    • v.3 no.1
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    • pp.1-6
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    • 2001
  • Silk protein has been investigated by many researchers to apply to biomedical field. We reviewed biomedical applications of silk protein such as matrix of wound dressing and drug delivery system. Since silk fibroin/ poly (ethylene glycol) (PEG) semi-interpenetrating polymer networks showed good mechanical properties and wound healing phenomena, it can be used as wound dressing materials. Sericin nanoparticles pre- pared by conjugation with PEG and silk protein/ poloxamer mixture gel are expected to become a deliv- ery as matrix for hydrophobic drug.

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