• 대한수의학회지
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• 제45권2호
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• pp.255-261
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• 2005

The purpose of this study is to compare hepatotoxicity of each treatment for dermatophytosis; one is the administration of the ketoconazole only and the other, ketoconazole with diphenyl-dimeththyl-dicarboxylate. Have chosen the range of 14-24 months of healthy dogs divided by two groups (group 1 and group 2) for the experiment of which test proved positive in dermatophytosis diagnosis and showed normal reaction in terms of physical examination, blood chemistry and especially of liver function. Group 1 was administrated ketoconazole orally at 10 mg/kg/day and of same dose of ketoconazole with diphenyl-dimethyl-dicarboxylate for group 2. After administering, we have tested two groups by blood collecting every one week in order to check the differences of hepatotoxicity state through AST, ALT and r-GTP, the barometers of liver function which lasted for 12 weeks. Moreover, tested Indocyanine Green (ICG), known as susceptible gauge of function of excretion before starting the experiment and tested ICG as well after 12 weeks. The experiment of result the value of group 1 in AST, ALT and r-GTP has been highly rised after administering ketoconazole for 10 weeks meanwhile, of group 2 has shown a steady state troughout the whole experiment. For ICG test, we injected 0.5 mg/kg of ICG into a vein for both groups and tested the retention rate at regular interval of 15, 30, 45 minutes. The results of retention rate in two groups were similar to before the drug administration. However, after 12 weeks the retention rate of group 1 has been delayed, on the other hand, retention rate of group 2 were a steady state. In conclusion, the administration of ketoconazole only for a long period of time induced hepatotoxicity where as, the administration of ketoconazole with diphenyl-dimethyl-dicarboxylate didn't induce hepatotoxicity. Therefore, when doctors prescribes for a dog with dermatophytosis should not administrate ketoconnazole itself but with diphenyl-dimethyl-dicarboxylate and one who has abnormal condition of liver function should not be prescribed ketoconazole treatment. If there is a case needed to prescribe ketoconazole treatment, the regular monitoring should be accompanied by at the same time.

• 대한치과보철학회지
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• 제19권1호
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• pp.39-45
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• 1981

Distal-extension removable partial dentures have long been implicated in the increase in mobility and the destruction of the supporting structures of the primary abutment teeth. Various clasping systems have traditionally been used to retain distal extension removable partial dentures, and other designs have been proposed to minimize torquing forces on the abutment teeth. Most recent studies investigating the effects of removable partial dentures on abutment teeth have been performed in it laboratory setting. Results obtained from in vitro research have given dentists insight into removable partial denture design, but laboratory test model cannot be constructed that simulates actual functional or parafunctiona1 movements and forces. The purpose of this study was to clinically evaluate the degree of tooth mobility produced by two clasping systems (suprabulge type and infrabulge type) used for distal extension removable partial dentures. Akers clasp and R.P.I. system were selected for the evaluation, and four patients required a distal extension removable partial denture on the mandibular arch were selected for participation in the study. Two partial dentures were constructed in the same condition expect the design of clasp. All abutments in the study were mandibular first or second premolars. Measurements of mobility were made with a research tool designed by $M\"{u}hlemann$. This instrument, periodontometer, measures tooth mobility in the mouth by means of a dial gauge accurated to 0.01mm when the tooth is stressed with a force meter. Lingual and buccal deflection of abutment tooth was measured using buccal and lingual pressure. The amount of force applied was 500gm. Tooth mobility tests were made at four key stages; 1. Before insertion of the first removable partial denture, baseline mobility was establsihed. 2. After wearing of the first prosthesis, measurement was made at weekly intervals for 4 weeks. 3. The removable partial denture was then taken from the patient, and tooth mobility was measured again at weekly intervals until the patient's established baseline mobility had returned. 4. The second prosthesis of different clasp design was worn for a month and evaluated in the same manner as the first. The sequence of placement of clasping system was alternated between patients. The following results were obtained from this study; 1. The mobility of abutment tooth increased during the initial stage of wear and returned to baseline mobility after removal of removable partial dentures. 2. The mobility of abutment tooth showed no difference between Akers clasp and I-bar clasp during the 4-week test period. 3. All teeth tested showed greater mobility toward the buccal than the lingual direction.

• 한국해안해양공학회지
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• 제14권1호
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• pp.51-64
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• 2002

협수로로 연결된 속초항과 청초호의 장주기파 공진을 검토하기 위하여 항내·외 8개 정점에서 파향·파고계, 초음파식 파고계, 수압식 파고계, 유속계 등을 이용하여 장·단주기파 현장관측을 실시하였다 자료 분석 결과 속초항과 청초호의 Helmholtz 공진 모드의 주기는 각각 13.6분과 54.5분으로 제시되었으며, 협수로 내 주된 유속의 출현 주기는 55.2분으로 청초호의 Helmholtz 공진 조건에 지배됨을 알 수 있었다. 저중력파로 인한 국부 부진동의 에너지 수준은 평상시보다 폭풍시에 훨씬 더 큰 것으로 나타났다. 항내·외 정점에서의 저중력파 파고와 항외의 단주기파고에 대한 회귀분석 결과 양자는 거의 선형적인 상관 관계를 가지는 것으로 나타났다. 그러나 양자의 주기들, 단주기 파향과 저중력파 파고, 단주기 파고와 저중력파 주기 사이에는 특별한 상관 관계를 발견하지 못하였다. 한편, 향후 장기간 자료가 축적되면 속초항 해역에서의 저중력파 파고에 대한 극치 해석을 통하여 재현빈도별 저중력파 파고를 추정할 수 있을 것으로 사료되었다.

• 한국지반신소재학회논문집
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• 제17권4호
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• pp.267-275
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• 2018

사방댐 배면의 준설퇴적물에 대한 준설시기를 객관적, 정량적, 과학적으로 결정할 수 있도록 준설퇴적물 측정장치를 개발하고 실제 현장에 시범 구축하였다. 사방댐 배면의 준설퇴적물 하중을 측정하기 위하여 준설퇴적물 관리시스템을 설계 및 개발하였다. 본 관리시스템은 Data Acquisition System (DAS), Solar System 및 준설퇴적물 하중변화 측정유닛으로 구성되어 있다. 또한 사방댐 배면의 준설퇴적물 하중, 수위 및 강우량을 실시간으로 측정하고 무선통신을 통하여 자료를 전송할 수 있다. 준설퇴적물 하중변화 측정유닛은 강우를 측정하기 위한 강우계, 사방댐 배면의 준설퇴적물 하중을 측정하기 위한 하중측정계, 사방댐 배면 수위를 측정하기 위한 수위계로 구성되어 있다. 사방댐 배면의 준설퇴적물 관리기준은 준설퇴적물의 하중을 기준으로 제안하였다. 사방댐 배면에 퇴적될 수 있는 최대 준설퇴적물의 양을 산정하고, 최대 준설퇴적물의 50%, 70% 및 90%가 쌓인 경우 관심, 주의 및 경보의 단계로 구분하여 관리기준을 마련하였다. 사방댐 배면의 준설퇴적물 관리시스템을 활용하여 현재 준설퇴적물의 하중을 실시간으로 측정할 수 있으며, 이를 토대로 사방댐의 상태와 준설퇴적물의 준설시기를 결정할 수 있을 것으로 판단된다.

• 예술인문사회 융합 멀티미디어 논문지
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• 제7권6호
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• pp.681-692
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• 2017

최근 들어 사회 간접시설 확충 및 경제발전 계획에 의하여 전국적으로 도로 확포장공사 및 신도시 건설 등 대규모 공사가 이루어지며 이로 인하여 인위적인 사면 훼손이 급격히 증가되고 있다. 기존의 비탈면녹화공법인 식생 기반재 취부공법은 결합력의 부족이나 건조화, 유기물의 부족 등의 문제점들을 보이고 있다. 본 연구에서는 천연부엽토, 바크퇴비, 코코피트, 질석이 포함되어 사용되고 있는 식생 기반재와 친환경적인 토양첨가제를 활용하여 연구수행을 하였다. 토양첨가제의 혼합비율에 따라 압축강도를 측정하였으며 식생 기반재와 토양첨가제를 혼합하여 흙다짐시험방법을 준용하여 몰드높이, 다짐횟수, 다짐방법(층), 양생 조건 등으로 하여 사면 보호용 녹생토 재료특성에 관한 실험을 진행하였다. 실험결과, 석고계 시멘트를 사용한 토양 첨가제에서 우수한 강도 성능이 나타났으며, 성능 향상제와 pH조절제를 사용함으로써 식생 생육기준에 만족하였다. 녹생토와 토양첨가제의 혼합에 따라 강도가 증가하는 것을 확인 할 수 있었으며, 사면 보호 안정성을 높일 수 있을 것으로 판단된다.

• 한국재료학회지
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• 제33권10호
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• pp.406-413
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• 2023

This study used optical and scanning electron microscopy to analyze the surface oxidation phenomenon that accompanies a γ'-precipitate free zone in a directional solidified CM247LC high temperature creep specimen. Surface oxidation occurs on nickel-based superalloy gas turbine blades due to high temperature during use. Among the superalloy components, Al and Cr are greatly affected by diffusion and movement, and Al is a major component of the surface oxidation products. This out-diffusion of Al was accompanied by γ' (Ni₃Al) deficiency in the matrix, and formed a γ'-precipitate free zone at the boundary of the surface oxide layer. Among the components of CM247LC, Cr and Al related to surface oxidation consist of 8 % and 5.6 %, respectively. When Al, the main component of the γ' precipitation phase, diffused out to the surface, a high content of Cr was observed in these PFZs. This is because the PFZ is made of a high Cr γ phase. Surface oxidation of DS CM247LC was observed in high temperature creep specimens, and γ'-rafting occurred due to stress applied to the creep specimens. However, the stress states applied to the grip and gauge length of the creep specimen were different, and accordingly, different γ'-rafting patterns were observed. Such surface oxidation and PFZ and γ'-rafting are shown to affect CM247LC creep lifetime. Mapping the microstructure and composition of major components such as Al and Cr and their role in surface oxidation, revealed in this study, will be utilized in the development of alloys to improve creep life.

• 한국재난정보학회 논문집
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• 제20권2호
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• pp.329-338
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• 2024

연구목적: 본 연구는 긴장방식을 복합적으로 적용한 세그멘탈 PSC U형 거더에 대한 해석적 거동을 기반으로 실대형 실험체의 휨 거동 결과를 평가하여 거동의 안전성을 검증하고자 한다. 연구방법: 도로교설계기준 한계상태설계법의 사용한계 및 극한한계상태 설계 결과를 바탕으로 40m 실대형 실험체의 가력하중을 산정하고 이에 대한 4점재하방식 정적 하중재하 실험을 수행하였다. 연구결과: 설계하중, 균열하중 및 극한하중이 작용할 때 해석적 처짐값 대비 97.1%, 98.5% 그리고 79.0%에 해당하는 실험체 처짐이 발생하였다. 설계하중, 균열하중 및 극한하중이 작용할 때 균열계는 각 연결부에서 0.009~0.035mm, 0.014~0.050mm, 6.383~5.522mm로 계측되었다. 결론: 균열하중 재하시까지 실험체는 탄성적으로 거동하였고 균열발생 후 극한하중까지 변형율-경화현상을 보이며 작용하중에 대하여 휨 저항 거동이 뚜렷이 나타났음을 확인하였다. 실대형 실험체 연결부(Dry Joint) 균열은 시설물 상태평가 B등급 기준 25% 미만의 결과로써 연결부의 탄성적 거동을 확인하였고 극한하중 제거 후 최종적 잔류 변형은 0.114mm로써 세그먼트 연결부의 안정적 거동을 확인하였다.

• 한국의류학회지
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• 제30권3호
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• pp.378-385
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• 2006

콘크리트포장에 초기균열을 일으키는 중요한 인자 중 하나는 콘크리트 내부의 초기온도이다. 따라서 콘크리트포장의 초기균열 발생원인을 연구하기 위해서는 초기온도를 계측하여 분석하는 일이 필요하다. 본 논문에서는 초기균열이 발생하는 슬래브 장소와 초기균열의 발생시간이 초기온도패턴에 어떤 영향을 받는지를 검증하였고 더불어, 줄눈부에서 발생하는 균열의 발생시점과 시공시간과의 관계도 알아보았다. 본 논문을 위해서 "중부내륙고속도로 여주-충주간 제 1공구 시험도로 건설공사구간 STATION 1+400$\sim$1+700" 지점에서 시험시공이 이루어졌으며, 시공 후 72시간 동안 i-Button(온도계측센서)을 이용하여 온도계측을 시행하였으며, 초기균열의 거동은 Demec gauge를 사용하였으며, 초기균열 및 줄눈부 균열은 육안으로 확인하였다. 초기온도패턴과 초기균열의 분석 결과, 콘크리트의 초기온도패턴은 슬래브에 초기균열이 발생하는 위치와 시각에 영향을 주는 것으로 나타났다 초기균열균열은 온도낙차폭이 가장 큰 슬래브에서 발생하였으며, 그 시각은 슬래브의 온도가 급강하하는 새벽이었다. 또한, 콘크리트 슬래브의 거동이 인근 줄눈부에 발생한 초기균열에 따라 영향을 받으며. 줄눈부에 발생한 균열의 발생시기가 서로 다를 경우에 균열의 거동이 달라질 수 있다는 가능성이 제시되었다. 그 외에도, 오전에 시공한 슬래브에서의 균열 발생률이 오후에 시공한것보다 더 큰 것으로 나타났으며, 균열의 발생 간격이 큰 균열이 그렇지 않은 균열보다 더 큰 균열틈을 보였다.

• 대한간호학회지
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• 제2권1호
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• pp.3-33
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• 1971

Nursing of today has as one of its objectives the solving of problems related to human needs arising from the demands of a rapidly changing society. This nursing objective, I believe, can he attained by the appropriate application of scientific principles in the giving of comprehensive nursing care. Comprehensive nursing care may be defined as nursing care which meets all of the patient's needs. the needs of patients are said to fall into five broad categories: physical needs, psychological needs, environmental needs, socio-economic needs, and teaching needs. Most people who become ill have adjustment problems related to their new situation. Because patient teaching is one of the most important functions of professional nursing, the success of this teaching may be used as a gauge for evaluating comprehensive nursing care. This represents a challenge foe the future. A questionnaire consisting of 67 items was distributed to 200 professional nurses working ill direct patient care at Yonsei University Medical Center in Seoul, Korea. 160 (80,0%) nurses of the total sample returned completed questionnaires 81 (50.6%) nurses were graduates of 3 fear diploma courser 79 (49.4%) nurses were graduates of 4 year collegiate nursing schools in Korea 141 (88,1%) nurses had under 5 years of clinical experience in a medical center, while 19 (11.9%) nurses had more than 5years of clinical experience. Three hypotheses were tested: 1. “Nurses had high levels of concept and knowledge toward patient teaching”-This was demonstrated by the use of a statistical method, the mean average. 2. “Nurses graduating from collegiate programs and diploma school programs of nursing show differences in concepts and knowledge toward patient teaching”-This was demonstrated by a statistical method, the mean average, although the results showed little difference between the two groups. 3. “Nurses having different amounts of clinical experience showed differences in concepts and knowledge toward patient teaching”-This was demonstrated by the use of a statistical method, the mean average. 2. “Nurses graduating from collegiate programs and diploma school programs of nursing show differences in concepts and knowledge toward patient teaching”-This was demonstrated by a statistical method, the mean average, although the results showed little difference between the two groups. 3. “Nurses having different amounts of clinical experience showed differences in concepts and knowledge toward patient teaching”-This was demonstrated by the use of the T-test. Conclusions of this study are as follow: Before attempting the explanation, of the results, the questionnaire will he explained. The questionnaire contained 67 questions divided into 9 sections. These sections were: concept, content, time, prior preparation, method, purpose, condition, evaluation, and recommendations for patient teaching. 1. The nurse's concept of patient teaching: Most of the nurses had high levels of concepts and knowledge toward patient teaching. Though nursing service was task-centered at the turn of the century, the emphasis today is put on patient-centered nursing. But we find some of the nurses (39.4%) still are task-centered. After, patient teaching, only a few of the nurses (14.4%) checked this as “normal teaching.”It seems therefore that patient teaching is often done unconsciously. Accordingly it would he desirable to have correct concepts and knowledge of teaching taught in schools of nursing. 2. Contents of patient teaching: Most nurses (97.5%) had good information about content of patient teaching. They teach their patients during admission about their diseases, tests, treatments, and before discharge give nurses instruction about simple nursing care, personal hygiene, special diets, rest and sleep, elimination etc. 3. Time of patient teaching: Teaching can be accomplished even if there is no time set aside specifically for it. -a large part of the nurse's teaching can be done while she is giving nursing care. If she believes she has to wait for time free from other activities, she may miss many teaching opportunities. But generally proper time for patient teaching is in the midmorning or midafternoon since one and a half or two hours required. Nurses meet their patients in all stages of health: often tile patient is in a condition in which learning is impossible-pain, mental confusion, debilitation, loss of sensory perception, fear and anxiety-any of these conditions may preclude the possibility of successful teaching. 4. Prior preparation for patient teaching: The teaching aids, nurses use are charts (53.1%), periodicals (23.8%), and books (7.0%) Some of the respondents (28.1%) reported that they had had good preparation for the teaching which they were doing, others (27.5%) reported adequate preparation, and others (43.8%) reported that their preparation for teaching was inadequate. If nurses have advance preparation for normal teaching and are aware of their objectives in teaching patients, they can do effective teaching. 5. Method of patient teaching: The methods of individual patient teaching, the nurses in this study used, were conversation (55.6%) and individual discussion (19.2%) . And the methods of group patient teaching they used were demonstration (42.3%) and lecture (26.2%) They should also he prepared to use pamphlet and simple audio-visual aids for their teaching. 6. Purposes of patient teaching: The purposes of patient teaching is to help the patient recover completely, but the majority of the respondents (40.6%) don't know this. So it is necessary for them to understand correctly the purpose of patient teaching and nursing care. 7. Condition of patient teaching: The majority of respondents (75.0%) reported there were some troubles in teaching uncooperative patients. It would seem that the nurse's leaching would be improved if, in her preparation, she was given a better understanding of the patient and communication skills. The majority of respondents in the total group, felt teaching is their responsibility and they should teach their patient's family as well as the patient. The place for teaching is most often at the patient's bedside (95.6%) but the conference room (3.1%) is also used. It is important that privacy be provided in learning situations with involve personal matters. 8. Evaluation of patient teaching: The majority of respondents (76.3%,) felt leaching is a highly systematic and organized function requiring special preparation in a college or university, they have the idea that teaching is a continuous and ever-present activity of all people throughout their lives. The suggestion mentioned the most frequently for improving preparation was a course in patient teaching included in the basic nursing program. 9. Recommendations: 1) It is recommended, that in clinical nursing, patient teaching be emphasized. 2) It is recommended, that insertive education the concepts and purposes of patient teaching he renewed for all nurses. In addition to this new knowledge, methods and materials which can be applied to patient teaching should be given also. 3) It is recommended, in group patient teaching, we try to embark on team teaching.

• 대한치과보철학회지
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• 제47권2호
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• pp.164-173
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• 2009

연구 목적: 심미적 장점을 지닌 지르코니아 지대주와 금속 지대주 사이에 반복 하중 전, 후의 풀림 회전력을 비교하여 지대주 재질에 따른 나사 안정성에 차이가 있는지를 비교 분석해 보고자 하는 것이다. 연구 재료 및 방법: 실험군은 크게 외측 연결 구조(US II, Osstem Implant, Korea)와 내측 연결 구조(GS II, Osstem Implant, Korea)의 임플란트 시스템을 두 군으로 나누었다. 각각의 군에서 지르코니아 지대주군와 금속 지대주군으로 나누어 실험하였다. 각군당5개씩의 시편을 제작하였다. 임플란트 고정체를 별도 제작된 지그에 고정시킨다. 디지털 토크게이지를 이용하여 30 Ncm의 조임 회전력을 가하고 10분 후 동일 조임 회전력을 한번 더 적용하였다. 다음 각 지대주 나사의 초기 풀림 회전력을 디지털 토크게이지로 측정하였다. 동일 시편을 다시 30 Ncm의 조임 회전력을 가하여 체결한 후, 유압식 동적 재료시험기(Instron, USA)에 임플란트 매식체를 치과용 임플란트 피로시험에 관한 ISO/FPIS 14801:2003(E)규정을 참고하여 고정시켰다. 최소 하중은 10 N, 최대 하중은 250 N의 sine형 반복 하중을 $30^{\circ}$의 경사각도로, 하중 주기는 14 Hz로, 100만 회의 반복 하중을 적용한 후 풀림 회전력을 측정하였다. 결과: 1. 모든 시스템에서 지대주 나사의 풀림 회전력이 조임 회전력 보다 감소하였으나, 나사 풀림 현상은 나타나지 않았다. 2. 반복 하중 전과 후의 나사 풀림 회전력은 두 임플란트 시스템 모두에서 지르코니아 지대주가 금속 지대주보다 더 컸다(P<.05). 3. 반복 하중에 따른 풀림 회전력 상실률은 두 임플란트 시스템 모두에서 지르코니아 지대주와 금속 지대주가 차이가 없는 것으로 나타났다(P>.05). 4. 금속 지대주에서 반복 하중에 따른 풀림 회전력 상실률은 내측 연결 형태의 GS II 시스템이 외측 연결형태의 US II 시스템보다 작았다(P<.05). 5. 지르코니아 지대주에서는 반복 하중에 따른 풀림 회전력 상실률은 두 임플란트 시스템 간에 차이가 없는 것으로 나타났다(P>.05). 결론: 본 실험을 통해 100만회 반복 하중 하에서 지르코니아 지대주가 금속 지대주에 비해 나사 결합부 안정성이 더 크다는 결론을 내릴 수 있다.