• 대한한방소아과학회지
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• 제22권2호
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• pp.217-225
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• 2008

Objectives : Prevalence of night eating habit associated with substance use and obesity is increasing rapidly in children and adolescents. Further, staying up late and eating snacks late at night were known as leading health risk behaviors for children, suggesting the potential adverse effect of night-eating habit on children. However, only few reports had been issued on the effect of night-eating habit on gastrointestinal symptom and SUI-TAI(水滯) symptom of children. Therefore, we aimed to investigate clinical characteristics of children by night-eating symptom status. Methods : Parents were asked to give a detailed answer to a systemized medical history questionnaire concerning night-eating habit, gastrointestinal symptom and SUI-TAI symptom of their children. Medical records of 28 children treated in the Department of Pediatrics, Hospital of Oriental Medicine, were the subject of this study. Clinical characteristics of two groups of children who with no night-eating habit and frequent night-eating group(eating at night more than 3 times per week) were analysed. In addition, the correlation analysis between clinical characteristics were performed. Results : Children with frequent night-eating habit(n=7, more than 3 days of night-eating a week) were observed to have more aggravated gastrointestinal symptom and SUI-TAI symptom compared with those without night-eating habit(n=13). In parallel, the association of gastrointestinal symptom and SUI-TAI symptom was demonstrated(n=28). Conclusions : It is notable that deranged gastrointestinal function and aggravated SUI-TAI symptom were observed among children generally regarded as healthy. Therefore, endeavors to correct night-eating habit as well as to treat aggravated gastrointestinal and SUI-TAI symptoms are needed for the promotion of health of children.

• 대한한의학회지
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• 제25권1호
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• pp.198-204
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• 2004

Backgrounds & Methods : Asthma is considered to be chronic inflammatory disease characterized by airway hyperresponsiveness and pulmonary eosinophilia. Recently, there has been many researches about asthma. IBS(Irritable Bowel Syndrome), PUD(peptic Ulcer disease) and GERD(gastroesophageal reflux disease) are the most common diseases of the gastrointestinal tract. Recent studies suggest that IBS, PUD and GERD are associated with bronchial hyper-responsiveness and bronchial asthma might be more prevalent in IBS and GERD patients than in control subjects. In addition, there are many comments about the interrelationship between the gastrointestinal problem and asthma in the oriental medical books. Actually, many oriental medical doctors don$^{\circ}$Øt consider the gastrointestinal condition when they deal with the asthmatic patients these days. So, we assessed the prevalence of gastrointestinal symptoms and histories in a cohort of patients with asthmatic symptoms. We evaluated 128 outpatients with asthmatic symptoms(60 males and 68 females, aged 13-75). All subjects enrolled completed the GSRS(Gastrointestinal Symptom Rating Scale). GSRS is an interview based rating scale consisting of 15 items for assessment of gastrointestinal symptoms in IBS and PUD developed by Jan Svedlund. Results : The limit of total score of GSRS in asthmatic patients is zero to 30. The number of patients with no GI symptoms is 66(51.5%). The number of patients with GSRS>5 is 62(48.4%), GSRS>10 is 24(18.8%), GSRS>15 is 8(6.25%). The number of patients with history of gastritis is 54(42.2%), gastric ulcer is 13(10.2%), gastroptosis is 8(6.25%), IBS is 6(4.68%), others is 6(4.68%). Conclusions : This study suggests that patients with bronchial asthma have an significant prevalence of gastrointestinal symptoms. Additional studies are needed to find the mechanism of the association between gastrointestinal symptoms and asthma.

• 정신신체의학
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• 제8권2호
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• pp.172-180
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• 2000

연구목적 : 상부 위장관의 소화 장애를 가진 환자들이 스트레스를 지각하였을 때 나타내는 반응 및 소화장애 증상의 여러 변인들과의 관계를 알아봄으로써 특정 정신신체질환군에서의 스트레스에 대한 반응특성과 해당 질환과의 연관성을 알아보고자 한다. 방법 : 소화장애 증상으로 인천기독병원 소화기내과를 방문하여 위내시경 소견 상 병변이 확인된 84명의 환자와 94명의 정상 대조군을 대상으로 국내에서 개발된 스트레스반응 지각척도를 사용하여 스트레스를 인지하였을 때 나타내는 반응을 비교분석하였다. 또한 환자군에서 현재 호소하는 소화장애 증상의 기간, 소화장애의 과거력, 증상의 심각도, 심리적 고통의 존재 여부에 따라 스트레스에 대한 지각반응이 어떻게 나타나는지 평가하였다. 결과 : 스트레스반응 지각척도는 8개의 하위척도로 구성되어 있으며 연구 대상자 178명에서 8개 하위척도와 척도전체의 내적 일치도는 .65~.95로써 통계적으로 유의하게 높았다. 환자군이 대조군에 비해서 척도의 전체총점과 일반적 신체증상척도, 특정신체증상척도의 접수가 통계적으로 유의하게 더 높았다. 소화장애 증상과 스트레스반응 지각척도와의 관련성은 소화장애의 기간, 소화장애의 과거력, 증상의 심각도는 특정신체증상을, 심리적 고통의 존재는 인지기능의 저하와 일반적 부정적 사고를 잘 예측해 주는 것으로 나타났다. 결론 : 실제 상부위장관에 병변을 가진 소화장애 환자들은 정상인에 비해서 강한 스트레스 반응 지각을 나타내었으며 특히 스트레스를 경험하고 인지하였을 때 감정, 인지, 행동 영역의 반응보다는 자율신경계 및 특정신체부위와 연관된 신체증상을 주로 경험하고 있음을 알 수 있다. 또한 이들은 소화장애의 기간이 길고, 과거력이 있을수록, 그리고 증상이 심할수록 스트레스에 대해 소화기 증상을 주로 한 특정신체증상으로 반응하며 심리적 고통을 주는 스트레스의 존재는 인지기능을 저하시키고 부정적인 사고반응을 일으킴을 알 수 있다.

• 대한한방내과학회지
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• 제40권4호
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• pp.629-636
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• 2019

Objective: This study was designed to assess the correlation between gastrointestinal symptoms, depression, and anxiety in patients with irritable bowel syndrome (IBS). Method: New patients who visited the ${\bigcirc}{\bigcirc}$ Oriental Hospital completed standardized questionnaires. These consisted of questionnaires for IBS based on Rome III criteria, the Gastrointestinal Symptom Rating Scale (GSRS), the Beck Depression Inventory (BDI), and the Beck Anxiety Inventory (BAI). Results: A total of 103 patients participated. Among them, IBS was observed in 42 patients. There was a weak correlation between GSRS and BDI, but it was not statistically significant. There was a statistically significant weak correlation between GSRS and BAI. The main symptom factors affecting BAI were borborygmus, increased flatus, sucking sensations in the epigastrium, and abdominal distension. Conclusion: There was a statistically significant correlation between gastrointestinal symptoms and anxiety in patients with irritable bowel syndrome.

• 대한한방내과학회지
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• 제40권5호
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• pp.878-887
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• 2019

Objective: The purpose of this case report was to report the effect of Gamchosasim-tang in patients with gastrointestinal symptoms due to gastric ulcer. Methods: We treated a patient suffering from epigastric pain, sucking sensations in the epigastrium, and nausea using Gamchosasim-tang (甘草瀉心湯) for 35 days. The patient's symptoms were charted and evaluated using a visual analogue scale (VAS) and a gastrointestinal symptom rating scale (GSRS). Results: After treatment, the symptoms related to gastric ulcer were decreased and evaluation using the VAS and GSRS showed improvement in the patient. Conclusion: This study shows that Korean medicine treatment with Gamchosasim-tang may be valuable for relieving gastric ulcer symptoms.

• 성인간호학회지
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• 제21권6호
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• pp.705-717
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• 2009

Purpose: The purpose of this study was to identify symptom clusters in patients with breast cancer and to investigate the associations among them with functional status and quality of life (QOL). Methods: A convenient sample of 303 patients was recruited from an oncology-specialized hospital. Results: Two distinct clusters were identified: A gastrointestinal- fatigue cluster and a pain cluster. Each cluster significantly influenced functional status and QOL. Based on these two clusters, we identified subgroups of symptom clusters using K-means cluster analysis. Three relatively distinct patient subgroups were identified in each cluster: mild, moderate, and severe group. Disease-related factors (i.e., stage, metastasis, type of surgery, current chemotherapy, and anti-hormone therapy) were associated with these subgroups of symptom clusters. There were significant differences in functional status and QOL among the three subgroups. The subgroup of patients who reported high levels of symptom clusters reported poorer functional status and QOL. Conclusion: Clinicians can anticipate that breast cancer patients with advanced stage, metastasis, and who receive mastectomy, and chemotherapy will have more intense gastrointestinal-fatigue or pain symptoms. In order to enhance functional status and QOL for patients with breast cancer, collective management for symptoms in a cluster may be beneficial.

• 동의신경정신과학회지
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• 제33권1호
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• pp.21-31
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• 2022

Objectives: To perform correlation analysis between the Core Seven Emotions Inventory-Short Form (CSEI-s), Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), upper gastrointestinal symptoms, and gastroscopic findings and to compare emotional characteristics with upper gastrointestinal endoscopic findings. Methods: In this study, medical records of 38 participants who visited the hospital for examination purposes or complained upper gastrointestinal symptoms and completed the CSEI-s, BAI, BDI, and Questionnaire for upper gastrointestinal symptoms were analyzed using SPSS (Statistical Package for the Social Sciences) version 25.0. Frequency Analysis, Descriptive Analysis, Independent t-test, Mann-Whitney's U-test, and Correlation analysis were performed. Results: The upper gastrointestinal symptom group showed higher levels of anger, sorrow, depression, and anxiety than the asymptomatic group. On gastroscopy, the normal group had higher levels of Joy than the abnormal group. The reflux esophagitis group showed higher levels of thought, depression, sorrow, and anxiety than the non-reflux esophagitis group. Joy showed a negative correlation with BDI score. However, anger, depression, sorrow, BAI, and BDI score showed positive correlations. Conclusions: Results of this study suggest that CSEI-s can be used to treat patients with upper gastrointestinal symptoms and reflux esophagitis.

• 동국한의학연구소논문집
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• 제6권2호
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• pp.109-133
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• 1998

근래 들어 악성종양의 발병률은 점점 상승하고 있으며 소화기암은 전체 악성종양중 높은 발생빈도를 보이는 질병으로 한의학계에서도 치료를 위해 많은 연구를 하고 있다. 소화기암의 증후와 치료에 관하여 열격, 반위(反胃), 적취(積聚), 장독(臟毒)을 위주로 명(明) 청대(淸代)까지의 역대(歷代) 문헌(文獻)을 통해 고찰(考察)한 결과 이는 복강내 악성종양과 증후에 있어서 유사성을 나타내며 치료는 초기에는 거사법(祛邪法)을, 중기에는 공보겸시(攻補兼施)를, 후기에는 부정법(扶正法)을 위주로 하는 것으로 나타났다. 역대 문헌에서는 이에 대한 처방구성을 다양하게 언급하여 향후 소화기암 치료에 응용할 수 있을 것으로 사료(思料)된다.

• 대한한방내과학회지
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• 제38권5호
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• pp.842-852
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• 2017

Objectives: This study reports the effects of GeonChil (Rhus verniciflua stokes) pharmacopuncture in patients with dyspepsia. Method: We treated all five patients with GeonChil pharmacopuncture, acupuncture, and moxibustion and evaluated them using the Korean Gastrointestinal Symptom Rating Scale (KGSRS), which is used to assess overall gastrointestinal symptoms. Result: After treatment, the KGSRS showed improvement in all five patients. Marked improvement was seen especially in abdominal pain, heartburn, eructation, and increased flatus symptoms. Conclusion: GeonChil pharmacopuncture may represent a new treatment for the improvement of dyspepsia.

• Journal of Digestive Cancer Research
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• 제3권2호
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• pp.76-81
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• 2015

Gastrointestinal side effects including nausea and vomiting, diarrhea, constipation, oral mucositis and colitis, and hepatotoxicity are common occurrence during chemotherapy. Often they result in unplanned admission and interruption of scheduled therapy. Additionally they have a negative influence on patient's therapeutic outcome and quality of life. The assessment of gastrointestinal side effects is dependent on clinician assignment of a grade established by the National Cancer Institute Common Terminology Criteria for Adverse Events. Continued interest of gastrointestinal side effects has allowed identifying patients at higher risk and providing effective treatments to relieve painful symptom. Finally, proper prevention and management of chemotherapy-induced gastrointestinal side effects will be needed to improve patient's survival and quality of life.