• Archives of Pharmacal Research
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• v.20 no.3
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• pp.212-217
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• 1997

Induction of an adaptive response to ionizing radiation in mouse lymphoma (EL4) cells was studied by using cell survival fraction and apoptotic nucleosomal DNA fragmentation as biological end points. Cells in early log phase were pre-exposed to low dose of ${\gamma}$-rays (0.01 Gy) 4 or 20 hrs prior to high dose ${\gamma}$-ray (4, 8 and 12 Gy for cell survival fraction analysis; 8 Gy for DNA fragmentation analysis) irradiation. Then cell survival fractions and the extent of DNA fragmentation were measured. Significant adaptive response, increase in cell survival fraction and decrease in the extent of DNA fragmentation were induced when low and high dose .gamma.-ray irradiation time interval was 4 hr. Addition of protein or RNA synthesis inhibitor, cycloheximide or 5,6-dichloro-1-.betha.-d-ribofuranosylbenzimidazole (DRFB), respectively during adaptation period, the period from low dose ${\gamma}$-ray irradiation to high dose ${\gamma}$-ray irradiation, was able to inhibit the induction of adaptive response, which is the reduction of the extent DNA fragmentation in irradiated EL4 cells. These data suggest that the induction of adaptive response to ionizing radiation in EL4 cells required both protein and RNA synthesis.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.55 no.3
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• pp.302-309
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• 2022

Low-salt fermented pollack Theragra chalcogramma roe (Myungran Jeotgal, MJ), a traditional Korean fermented seafood, was prepared using a commercially available method and irradiated using gamma rays (0-10.0 kGy) to investigate the effect of gamma irradiation (GI) on food quality. After irradiation with 2.5 kGy gamma rays, the number of viable cells in MJ was reduced by one log compared to that observed in non-irradiated MJ, and no living cells were detected after 7.5 kGy GI. Though up to 2.5 kGy GI had no effect on color quality, over 7.5 kGy GI resulted in significantly poor quality MJ surface color. Saturated fatty acid contents increased slightly in irradiated MJ, while those of polyenes and monoenes decreased slightly as the GI dose increased. Exposure of MJ to GI had no effect on the free amino acid and mineral composition. These results demonstrated that the appropriate GI dose for MJ ranged from 2.5 to 5.0 kGy, which may be recommended for industrial application.

• Journal of Yeungnam Medical Science
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• v.39 no.2
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• pp.108-115
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• 2022

Background: This study was aimed at comparing and analyzing the results of FractionLab (Varian/Mobius Medical System) with those of portal dosimetry that uses an electronic portal imaging device. Portal dosimetry is extensively used for patient-specific quality assurance (QA) in intensity-modulated radiotherapy (IMRT). Methods: The study includes 29 patients who underwent IMRT on a Novalis-Tx linear accelerator (Varian Medical System and Brain-LAB) between June 2019 and March 2021. We analyzed the multileaf collimator DynaLog files generated after portal dosimetry to evaluate the same condition using FractionLab. The results of the recently launched FractionLab at various gamma indices (0.1%/0.1 mm-1%/1 mm) are analyzed and compared with those of portal dosimetry (3%/3 mm). Results: The average gamma passing rates of portal dosimetry (3%/3 mm) and FractionLab are 98.1% (95.5%-100%) and 97.5% (92.3%-99.7%) at 0.6%/0.6 mm, respectively. The results of portal dosimetry (3%/3 mm) are statistically comparable with the QA results of FractionLab (0.6%/0.6 mm-0.9%/0.9 mm). Conclusion: This paper presents the clinical performance of FractionLab by the comparison of the QA results of FractionLab using portal dosimetry with various gamma indexes when performing patient-specific QA in IMRT treatment. Further, the appropriate gamma index when performing patient-specific QA with FractionLab is provided.

• Bulletin of the Korean Mathematical Society
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• v.33 no.1
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• pp.111-118
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• 1996

Throughout this paper Z and C will respectively denote the ring of rational integers and the complex number field.

• Korean journal of food and cookery science
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• v.17 no.6
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• pp.617-624
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• 2001

Gamma irradiation (1-10 kGy) was applied to chicken for the evaluation of their microbiological safety and possible genotoxicity. In 3 kGy-irradiated sample, the growth of psychrophile was inhibited about 1.5 log cycles and no cells were recovered in total microbial counts. All kinds of contaminated microorganism were sterilized by 7 kGy-irradiation. Also, irradiation followed by freeze-storage at the same time was very effective in inhibiting bacterial growth. The genotoxicity of 10 kGy-irradiated chicken was evaluated by Salmonella Typhimurium reversion assay and in vivo micronucleus assay using mouse bone marrow cells. The results were negative in the bacterial reversion assay with S. Typhimurium TA98, TA100, TA1535, and TA1539. Clastogenic effects were not shown in vivo mouse micronucleus assay at 10 kGy-dose tested.

• Economic and Environmental Geology
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• v.51 no.1
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• pp.39-48
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• 2018

We carried out the standoff compensation data from 2007 to 2011 into four different density borehole models to find out the most effectiveness of standoff compensation charts. First, we investigated the irregular collapse characteristics of gamma ray and cut the non-ideal gamma response to improve the effectiveness of the standoff compensation error data. Effectiveness of detector combinations, density of borehole, and spine and ribs techniques from the modified standoff compensation data was analyzed. As the result of comparison, LSD-MSD combination has been suitable for standoff compensation more than LSD-SSD combination and it is possible to do standoff compensation for soil or weathered zone under groundwater level without fatal errors. Even though error scales of density transformed spine and ribs techniques were generally large compared to the conventional standoff compensation, standoff compensation for soil and weathered zone under groundwater level were sufficiently effective.

• Progress in Medical Physics
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• v.32 no.4
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• pp.107-115
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• 2021

Purpose: The purpose of this study was to compare the clinical quality assurance results of portal dosimetry using an electronic portal imaging device, a method that is extensively used for patient-specific quality assurance, and the newly released Mobius3D for intensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT). Methods: This retrospective study includes data from 122 patients who underwent IMRT and VMAT on the Novalis Tx and VitalBeam linear accelerators between April and June 2020. We used a paired t-test to compare portal dosimetry using an electronic portal imaging device and the average gamma passing rates of MobiusFX using log files regenerated after patient treatment. Results: The average gamma passing rates of portal dosimetry (3%/3 mm) and MobiusFX (5%/3 mm) were 99.43%±1.02% and 99.32%±1.87% in VitalBeam and 97.53%±3.34% and 96.45%±13.94% in Novalis Tx, respectively. Comparison of the gamma passing rate results of portal dosimetry (3%/3 mm) and MobiusFX (5%/3 mm as per the manufacturer's manual) does not show any statistically significant difference. Conclusions: Log file-based patient-specific quality assurance, including independent dose calculation, can be appropriately used in clinical practice as a second-check dosimetry, and it is considered comparable with primary quality assurance such as portal dosimetry.

• Journal of The Korean Astronomical Society
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• v.43 no.5
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• pp.141-152
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• 2010

UBV I CCD photometry is obtained for the open clusters NGC 4609 and Hogg 15 in Crux. For NGC 4609, CCD data are presented for the first time. From new photometry we derive the reddening, distance modulus and age of each cluster - NGC 4609 : E(B-V ) = $0.37{\pm}0.03$, $V_0-M_V=10.60{\pm}0.08$, log $\tau$= 7.7 $\pm$ 0.1; Hogg 15 : E(B - V ) = 1.13 $\pm$ 0.11, $V_0-M_V$ = 12.50 $\pm$ 0.15, log $\tau$ $\lesssim$ 6.6. The young age of Hogg 15 strongly implies that WR 47 is a member of the cluster. We also determine the mass function of these clusters and obtain a slope $\Gamma$ = -1.2 ($\pm$0.3) for NGC 4609 which is normal and a somewhat shallow slope (${\Gamma}=-0.95{\pm}0.5$) for Hogg 15.

• Journal of the Korean Chemical Society
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• v.14 no.3
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• pp.213-219
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• 1970

In the presence of hydrogen peroxide, the effects of temperature and pH to the catalytic reaction velocity of cupric -thiocyanate and the quantities of reduction products adsorbed on the D.M.E. have been studied by polarographic method. According to these experiments, the following empirical equation has been derived for the relation among temperature $T_i$, concentration of hydrogen ion $pH_i$ and adsorbed cuprous-thiocyanate in moles/$cm^2Z_{ij}$, and rate constant log$K_{ij}$ $$log\;K_{ij}=\frac{1}{T_i}\{A(pH_j)+B\}+C(pH_j)+D$$ $$Z_{ij}=\frac{1}{T_i}\{{\alpha}(pH_j)^{\frac{1}{2}}+{\beta}\}+{\gamma}(pH_j)^{\frac{1}{2}}+{\delta}$$ where, A,B,C,D and {$\alpha},{\beta},{\gamma},{\delta}$ are constants. The Calculated values by both equations are well agreed with empirical values within 8% in the error.

• Journal of the Korean Chemical Society
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• v.37 no.1
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• pp.148-153
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• 1993

The Wallach rearrangement of 4'-halogenated azoxybenzenes in strong sulfuric acid was reinvestigated by UV-Vis spectrophotometric method. Interestingly an excellent linearity $(logk_{obs}=-0.61\;{\sigma}_R{^+} -3.29,\;{\gamma = 0.998)$ was obtained on plotting log (rate) vs. substituent constant, ${\sigma}_R{^+}$, which is known as the Pi delocalization parameter. Thus B-H mechanism via a charged intermediate $(DC^{++})$, which can be largely stabilized by resonance, is far more favored for the Wallach rearrangement.