• Nuclear Engineering and Technology
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• 제54권3호
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• pp.1016-1023
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• 2022

In proton therapy, a highly conformal proton dose can be delivered to the tumor by means of the steep distal dose penumbra at the end of the beam range. The proton beam range, however, is highly sensitive to range uncertainty, which makes accurately locating the proton range in the patient difficult. In-vivo range verification is a method to manage range uncertainty, one of the promising techniques being prompt gamma imaging (PGI). In earlier studies, we proposed gamma electron vertex imaging (GEVI), and constructed a proof-of-principle system. The system successfully demonstrated the GEVI imaging principle for therapeutic proton pencil beams without scanning, but showed some limitations under clinical conditions, particularly for pencil beam scanning proton therapy. In the present study, we upgraded the GEVI system in several aspects and tested the performance improvements such as for range-shift verification in the context of line scanning proton treatment. Specifically, the system showed better performance in obtaining accurate prompt gamma (PG) distributions in the clinical environment. Furthermore, high shift-detection sensitivity and accuracy were shown under various range-shift conditions using line scanning proton beams.

• 비파괴검사학회지
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• 제14권4호
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• pp.228-236
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• 1995

본 연구에서는 비파괴검사 방법의 하나인 gamma scanning test에 의한 대단위 차폐체의 결함을 평가하는 방법을 제시하고 방사선 차폐를 해석하는 유용한 방법중의 하나인 Monte Carlo 코드로 이에 대한 검증을 하였다. Gamma scanning test로 차폐체의 결함을 평가하기 위한 모델은 원통형 차폐체를 대상으로 하였다. 먼저 방사성물질 운반용기에 대한 설계기준에 따라 기준차폐체를 설치하여 Co-60 선원과 섬광계수기로 기준치를 측정하고, 그 다음 실물의 원통형 차폐체를 측정하였다. 기준치로 원통형 차폐체의 납두께를 환산한 결과 결함두께는 최대 12mm로 평가되었다. 이를 검증하기 위한 MCNP 코드의 계산에서는 결함두께가 실험적 결과에 비해 4.1%에 해당하는 최대 11.6mm를 나타내었으며, 두 결과가 만족할 정도로 일치함을 보여주고 있다. 따라서 이러한 평가방법은 방사성물질을 사용하는 시설에 설치되는 대단위 방사선 차폐체나 대용량의 운반용기 차폐능 검사시 현장에서 적용시킬 수 있으며 측정치의 신뢰도를 제고할 수 있다. 앞으로 보다 정확한 측정을 위하여 차폐체의 두께 측정결과가 화면에 직접 표시되는 측정장치의 연구 개발이 요구된다.

• Nuclear Engineering and Technology
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• 제30권5호
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• pp.452-461
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• 1998

The pin power distribution is determined by analyzing the rotational gamma scanning data for 36 element fuel bundle of HANARO. A fission monitor of Nb$^{95}$ is chosen by considering the criteria of the half-life, fission yield, emitting ${\gamma}$-ray energy and probability. The ${\gamma}$-ray spectra were measured in Korea Atomic Energy Research Institute(KAERI) by using a HPGe detector and by rotating the fuel bundle at steps of 10$^{\circ}$. The counting rates of Nb$^{95}$ 766 keV ${\gamma}$-rays are determined by analyzing the full absorption peak in the spectra. A 36$\times$36 response matrix is obtained from calculating the contribution of each rod at every scanning angle by assuming 2-dimensional and parallel beam approximations for the measuring geometry. In terms of the measured counting rates and the calculated response matrix, an inverse problem is set up for the unknown distribution of activity concentrations of pins. To select a suitable solving method, the performances of three direct methods and the iterative least-square method are tested by solving simulation examples. The final solution is obtained by using the iterative least-square method that shows a good stability. The influences of detection error, step size of rotation and the collimator width are discussed on the accuracy of the numerical solution. Hence an improvement in the accuracy of the solution is proposed by reducing the collimator width of the scanning arrangement.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2003년도 학술회의 논문집 정보 및 제어부문 B
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• pp.612-615
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• 2003

In this paper, a design of radiation detector for gamma column scanner is introduced. Distillation column is important unit in Petro-chemical industries, and its on-line diagnose is very important. To get density profile measured by the radiation transmitted through column is well method for on-line diagnose as gamma scanning. For this purpose radiation detection circuit, radiation source and mechanical system for moving source and detector are required. Conventional radiation detection circuit for this application is sensitive to electric noise because of interface between the radiation circuit and the controller for mechanical system. The radiation detection system introduced here is using loop coil instead of slip ring to remove contact noise. Radiation detection system designed here for gamma scanning consist of BGO detector, high voltage circuit, PHA circuit and FSK modem. The BGO detector is used as radiation sensor, high voltage circuit and peak height analysis circuit is essential to process the signal generated from BGO detector. Micro controller convert measured data into ASCII data. FSK modem transmit ASCII data. Transmitted ASCH data is picked up in antenna coil and processed for combined function with mechanical system. This method gives good result by isolating the controlling circuit of mechanical system from radiation detecting circuit which is sensitive to noise.

• Nuclear Engineering and Technology
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• 제54권6호
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• pp.2213-2220
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• 2022

The maximum dose delivery at the end of the beam range provides the main advantage of using proton therapy. The range of the proton beam, however, is subject to uncertainties, which limit the clinical benefits of proton therapy and, therefore, accurate in vivo verification of the beam range is desirable. For the beam range verification in spot scanning proton therapy, a prompt gamma detection system, called as gamma electron vertex imaging (GEVI) system, is under development and, in the present study, the performance of the GEVI system in spot scanning proton therapy was predicted with Geant4 Monte Carlo simulations in terms of shift detection sensitivity, accuracy and precision. The simulation results indicated that the GEVI system can detect the interfractional range shifts down to 1 mm shift for the cases considered in the present study. The results also showed that both the evaluated accuracy and precision were less than 1-2 mm, except for the scenarios where we consider all spots in the energy layer for a local shifting. It was very encouraging results that the accuracy and precision satisfied the smallest distal safety margin of the investigated beam energy (i.e., 4.88 mm for 134.9 MeV).

• Nuclear Engineering and Technology
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• 제51권3호
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• pp.800-806
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• 2019

This paper presents a laboratory experiment on data acquisition technique that applied to the gamma radiation scanning coupled with computed tomography (CT) technique for inspection of broken nozzle inside the vertical vessel. The acquisition technique was developed to inspect a large diameter vessel when suspicious problem location is not easily accessed. This technique allows the installation of gamma radiation source (Cesium 137, Cs-137), and detectors (Sodium Iodine. NaI(Tl)) from the accessible location to the required location and performs the scanning by designed pattern. To demonstrate the designed technique, top opened tank which installed with six cut steel pipes diameter of 76.2 mm (3") at a certain position was selected. They were assumed to be a gas riser pipes inside the vessel. Three studied cases were performed, (a) projection of well installed six pipes, (b) projection of one out of six broken pipe and (c) one of nozzle was assumed to be failure and fell down until one out of six pipes was broken and obstructed by nozzle. Results clearly indicated the capability of developed technique to distinguish between normal situation case and abnormal situation cases.

• 비파괴검사학회지
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• 제9권2호
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• pp.8-17
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• 1989

Reconstruction of the radial two-dimensional of fission products using projections obtained by nondestructive transversal direction gamma scanning was evaluated, and then compared with the destructive sectional gamma scanning results. Although the nondestructive method has a little drawback compared to the destructive method in the accuracy, the former seemed to be sufficiently applicable.

• 한국재료학회지
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• 제18권11호
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• pp.577-582
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• 2008

Directional solidification experiments were carried out at $1-300\;{\mu}m/sec$ solidification rates in the single crystal superalloy, CMSX 10. The solid/liquid interface morphology changed from planar to dendritic, and the dendrite spacing became finer as the solidification rate increased. The pool size of the ${\gamma}/{\gamma}'$ eutectic, formed between dendrites, reduced as the solidification rate increased. The phase formation temperatures, such as the solidus, liquidus and eutectic, were estimated by differential scanning calorimetry (DSC) analysis. The morphology of the ${\gamma}/{\gamma}'$ phase, known to be eutectic, showed ${\gamma}'$ cells with a $\gamma$ intercellular network, and this ${\gamma}/{\gamma}'$ was composed of coarse and fine ${\gamma}/{\gamma}'$ regions. In this study, it is suggested that the ${\gamma}/{\gamma}'$ phase was a coupled peritectic.The solidification procedure of the ${\gamma}/{\gamma}'$ between dendrites is also discussed.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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• pp.191.1-191.1
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• 2014

Crystallization has become the most popular technique for the separation of enantiomers since the Pasteur's discovery. To investigate mechanism of crystallization of chiral molecules, it is necessary to study self-assembled structures on two-dimensional surface. Here, we have studied two-dimensional self-assembled structures of an unnatural amino acid, (S)-${\beta}$-methyl naphthalen-1-${\gamma}$-aminobutyric acid (${\gamma}^2$-1-naphthylalanine) on Au(111) surface at 150 K using scanning tunneling microscopy (STM). At initial stage, we found two chiral honeycomb structures which are counter-clockwise and clockwise configurations in one domain. The molecules are arranged around molecular vacancies, dark hole. By further increasing the amounts of adsorbed ${\gamma}^2$-1-naphthylalanine, a well-ordered square packed structure was observed. In addition, we found the other structure that molecules were trapped in the pore of the hexagonal molecular assembly.

• 약학회지
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• 제39권2호
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• pp.175-184
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• 1995

The interaction of omeprazole(OMP) with $\gamma$-cyclodextrin($\gamma$-CyD) was investigated by solubility study and the complexation was confirmed by means of UV/VIS spectrophotometer, circular dichroism, differential scanning calorimeter, and $^{1}$H nuclear magnetic resonance spectra. The stability, dissolution rate, and partition coefficient of the complex were measured. The results present that the benzimidazole moiety and a part of pyridine ring containing sulfur atom of OMP might be included into the cavity of $\gamma$-CyD and the formation type of inclusion complex appeared to be B$_{s}$. The stoichiometric ratio of OMP to $\gamma$-CyD in the complex was found to be 1:1 and the stability constant of the complex found to be 97.1 M$^{-1}$. And the dissolution rate of OMP was markedly increased by inclusion complex formation with $\gamma$-CyD, and so it was above 90% in 5 min. from solid complex. Oil to water partition coefficient of OMP-$\gamma$-CyD complex was 60, which is significantly higher than that of OMP itself, 36.4. The degradation rate constant of OMP were greater than OMP-$\gamma$-CyD complex in aqueous solutions of various pHs, and the half lives of OMP and OMP-$\gamma$-CyD at pH 9 were 279.2 and 509.9 days, respectively, showing that the complex was more stable than OMP, therefore it was thought that OMP was stabilized by inclusion formation with $\gamma$-CyD.