• Journal of Ginseng Research
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• v.41 no.2
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• pp.144-150
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• 2017

Background: The presence of gross deletions in the human immunodeficiency virus nef gene ($g{\Delta}nef$) is associated with long-term nonprogression of infected patients. Here, we investigated how quickly genetic defects in the nef gene are associated with Korean Red Ginseng (KRG) intakein 10 long-term slow progressors. Methods: This study was divided into three phases over a 20-yr period; baseline, KRG intake alone, and KRG plus highly active antiretroviral therapy (ART). nef gene amplicons were obtained using reverse transcription polymerase chain reaction (PCR) and nested PCR from 10 long-term slow progressors (n = 1,396), and nested PCR from 36 control patients (n = 198), and 28 ART patients (n = 157), and these were then sequenced. The proportion of $g{\Delta}nef$, premature stop codons, and not in-frame insertion or deletion of a nucleotide was compared between three phases, control, and ART patients. Results: The proportion of defective nef genes was significantly higher in on-KRG patients (15.6%) than in baseline (5.7%), control (5.6%), on-KRG plus ART phase (7.8%), and on-ART patients (6.6%; p < 0.01). Small in-frame deletions or insertions were significantly more frequent among patients treated with KRG alone compared with controls (p < 0.01). Significantly fewer instances of genetic defects were detected in samples taken during the KRG plus ART phase (7.8%; p < 0.01). The earliest defects detected were $g{\Delta}nef$ and small in-frame deletions after 7 mo and 67 mo of KRG intake, respectively. Conclusion: KRG treatment might induce genetic defects in the nef gene. This report provides new insight into the importance of genetic defects in the pathogenesis of AIDS.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.16 no.2
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• pp.69-76
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• 2023

A high-quality audio/voice codec using the MDCT/IMDCT process can perfectly restore the current frame through an overlap-add process with the previous frame. In the overlap-add process, an algorithm delay equal to the frame length occurs. In this paper, we propose a MDCT/IMDCT process that reduces algorithm delay by using a variable phase shift in MDCT/IMDCT process. In this paper, a low-delay audio/speech codec was proposed by applying the low delay MDCT/IMDCT algorithm to the ITU-T standard codec G.729.1 codec. The algorithm delay in the MDCT/IMDCT process can be reduced from 20 ms to 1.25 ms. The performance of the decoded output signal of the audio/speech codec to which low-delay MDCT/IMDCT is applied is evaluated through the PESQ test, which is an objective quality test method. Despite of the reduction in transmission delay, it was confirmed that there is no difference in sound quality from the conventional method.

• Proceedings of the Korean Society For Composite Materials Conference
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• 2004.10a
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• pp.232-235
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• 2004

This is the preliminary study to develop composite window frame of commercial aircraft using VaRTM process. For two candidate carbon fabric(triaxial fabric, sleeving braider dry carbon fiber), specimens were fabricated using VaRTM process ,and then the physical & mechanical tests were performed to gain material property according to ASTM. FEM analysis for each candidate carbon fabric were performed to find the minimum ply number and weight for composite window frame. In this study Tsai-Wu strength failure criteria was utilized to evaluate the safety of structure.

• Proceedings of the KIEE Conference
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• 1998.07a
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• pp.200-204
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• 1998

In this paper, a mathematical model of Brushless DC machine fed by pwm inverter is developed. Dynamic and steady state characteristics of Brushless DC motor is simulated and analyzed: electromagnetic torque, speed, phase voltage, and current. In mathematical modeling, the shaft transformation referencing rotor frame from to "a,b,c" three phase frame to "d,g" two phase frame is described.

• Steel and Composite Structures
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• v.11 no.1
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• pp.21-38
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• 2011

This study examines the influence of curved, steel, I-girder bridge configuration on girder end reactions and cross frame member forces during seismic events. Simply-supported bridge finite element models were created and examined under seismic events mimicking what could be experienced in AASHTO Seismic Zone 2. Bridges were analyzed using practical ranges of: radius of curvature; girder and cross frame spacings; and lateral bracing configuration. Results from the study indicated that: (1) radius of curvature had the greatest influence on seismic response; (2) interior (lowest radius) girder reactions were heavily influenced by parameter variations and, in certain instances, uplift at their bearings could be a concern; (3) vertical excitation more heavily influenced bearing and cross frame seismic response; and (4) lateral bracing helped reduce seismic effects but using bracing along the entire span did not provide additional benefit over placing bracing only in bays adjacent to the supports.

• Smart Structures and Systems
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• v.25 no.1
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• pp.47-56
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• 2020

This paper proposes a model-based approach for structural damage identification and quantification. Using pseudo modal strain energy and mode shape vectors, a damage-sensitive objective function is introduced which is suitable for damage estimation and quantification in shear frames. Whale optimization algorithm (WOA) is used to solve the problem and report the optimal solution as damage detection results. To illustrate the capability of the proposed method, a numerical example of a shear frame under different damage patterns is studied in both ideal and noisy cases. Furthermore, the performance of the WOA is compared with particle swarm optimization algorithm, as one the widely-used optimization techniques. The applicability of the method is also experimentally investigated by studying a six-story shear frame tested on a shake table. Based on the obtained results, the proposed method is able to assess the health of the shear building structures with high level of accuracy.

• Transactions of the Korean Society of Automotive Engineers
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• v.6 no.6
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• pp.107-112
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• 1998

A great deal of time and effort are required to evaluate the safety and durability of a vehicle structure in the vehicle development stage. It is difficult to find the reasons for cracks which occur in the body and frame of a vehicle during tests. Recently computer aided engineering techniques have been utilized to solve the problems of safety and durability of vehicles. In this study, a dynamic stress analysis is performed on the frame of the vehicle by rigid and flexible multibody dynamics techniques. The result of the analysis is compared to that of the actual test. The full vehicle dynamic models for the rigid and flexible bodies are developed by DADS package. The modal coordinate system is used to save time for the dynamic stress analysis. The flexible multibody dynamic models have 12 normal modes considering the flexibility of the frame. Dynamic stresses arc calculated by relating the stress influence coefficients and the applied forces.

• Korean Journal of Agricultural Science
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• v.37 no.2
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• pp.271-276
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• 2010

In this study, the light-frame wood shear walls according to the sheathing materials was carried out to investigate the shear load performance. Most common sheathing materials are the structural OSB and gypsum board used to consist wall of wood-frame house. Seven different type of specimens are composed of several sheathing materials and shear test was taken to evaluate shear performance by KS F 2154. As a result, shear walls(G12.5/G12.5 and G12.5/OSB) show that maximum shear strength and shear rigidity modulus are 7316N/mm${\cdot}$118.25 N/mm and 11129 N/mm${\cdot}$184.66 N/mm respectively. The shear wall using gypsum board 15mm improve maximum shear strength and shear rigidity modulus about 30%. The shear wall using 15mm gypsum board showed intermediate value in one side specimens. Different types of shear walls could be compared with the shear load performance. Also, nailed joint failure aspects are different to sheathing material and installing method.

• Journal of the Korea Institute of Military Science and Technology
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• v.27 no.1
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• pp.24-30
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• 2024

The gas-gun test is a experimental approach employed to validate the operational or structural stability when subjected to the impact energy encountered during launch or target collision. Predicting the outcomes of the gas-gun test has traditionally relied on empirical knowledge, due to numerous factors such as the bird assembly's shape, weight, material, and flight velocity. However, due to the nonlinearity and complex interactions between these variables, numerous tests are necessary to identify the necessary requirements, resulting in significant expense and time consumption during the process. The objective of this study is to forecast the variations in impact energy in future tests by developing a numerical model and analysis that aligns with the test outcomes, utilizing the ABAQUS Explicit. The outcome of the numerical analysis produced a framework that anticipates the peak g and the duration of the actual gas-sun test results, throughout post-processing techniques using FFT and LPF filters.

• Journal of the Institute of Electronics and Information Engineers
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• v.49 no.12
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• pp.64-72
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• 2012

Synchronization including timing recovery, frequency offset compensation, and frame synchronization is most important signal processing block in all wireless/wired communication systems. In most communication systems, synchronization schemes based on training sequences or preambles are used. WLAN standards of 802.11a/g/n released by IEEE are based on OFDM systems. OFDM systems are known to be much more sensitive to frequency and timing synchronization errors than single carrier systems. A loss of orthogonality between the multiplexed subcarriers can result in severe performance degradations. The starting position of the frame and the beginning of the symbol and training symbol can be estimated using correlation methods. Correlation processing functionality is usually complex because of large number of multipliers in implementation especially when the reference signal is non-binary. In this paper, a simple correlation based synchronization scheme is proposed for IEEE 802.11a/g/n systems. Existing property of a periodicity in the training symbols are exploited. Simulation and implementation results show that the proposed method has much smaller complexity without any performance degradation than the existing schemes.