• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.11 no.1
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• pp.17-24
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• 2005

During handling unitized products, they are subjected to a variety environmental hazards. Shock and vibration hazards are generally considered the most damaging of the environmental hazards on a product, and it may encounter while passing through the distribution environment. A major cause of shock damage to products is drops during manual handling. The increasing use of unitization on pallets has been resulted in a reduction in the manual handling of products and with it a reduction in the shock hazards. This has caused and increasing interest in research focused on vibration caused damage. the use of pallets as a base for unitizing loads, aids in the mechanical handling, transportation and storage of products. Besides aiding in the handling, transportation and storage of products, a pallet also acts on and interface between the packaged goods and the distribution environment. The determination of the impact deformation of the cushioning materials such as tray cup (polymeric foam) and corrugated fiberboard pad must be carried out to design the proper packaging system providing adequate protection for the fruit, and to understand the complex interaction between the components of fruit when they relate to expected transportation vibration inputs. In this study, the theoretical analysis of impact deformation for cushioning materials by dynamic vibration. The impact deformations of SW and DW corrugated fiberboard pad in acceleration amplitudes of 0.25 G-rms and 0.5 G-rms that were usually generated in transport vehicles during distribution environments were very small compare with the thickness of corrugated fiberboard pad. The maximum of vibration acceleration level of tray cup by vibration impact was about 3.2 G-rms. The theoretical allowable acceleration (G-factor) of the pear was 0.7102 G-rms, and the maximum dynamic deformation estimated within G-factor was about 1 mm.

• 한국체육학회지인문사회과학편
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• v.55 no.4
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• pp.343-350
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• 2016

The purpose of this study is to phenomenological analyze the fun experience of G-Golf Tour players. A total of 3 male and 3 female professional golfers who are currently participate in G-Golf Tour are selected by snow-ball sampling. Data was collected from interviews and participant observation, With this data, coding was done as first step and group categorization was done as second step in order to achieve the right result from meaningful analyzing. In order to approve the adequate of this study, the peer review was done by one qualitative research specialist and two candidates of Ph.D. The motivation of G-Tour participation, the notification changing of G-Tour, the addiction of G-Tour, the fun factor of G-Tour were drawn as the results, and the media exposure, personal relations, and skill improvement were drawn as the sub-factors of fun experience of G-Tour.

• Geomechanics and Engineering
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• v.31 no.4
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• pp.423-437
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• 2022

The objective of the study is to evaluate the feasibility of the dynamic behavior of slope through both 1 g shaking table test and numerical analysis. Accelerometers were installed in the slope model with different types of seismic waves. The numerical analysis (ABAQUS and DEEPSOIL) was used to simulate 1 g shaking table test at infinite boundary. Similar Acceleration-time history, Spectral acceleration (SA) and Spectral acceleration amplification factor (Fa) were obtained, which verified the feasibility of modeling using ABAQUS and DEEPSOIL under the same size. The influence of the size (1, 2, 5, 10 and 20 times larger than that used in the 1 g shaking table test) of the model used in the numerical analysis were extensively investigated. According to the similitude law, ABAQUS was used to analyze the dynamic behavior of large-scale slope model. The 5% Damping Spectral acceleration (SA) and Spectral acceleration amplification factor (Fa) at the same proportional positions were compared. Based on the comparison of numerical analyses and 1 g shaking table tests, it was found that the 1 g shaking table test result can be utilized to predict the dynamic behavior of the real scale slope through numerical analysis.

• Journal of Pharmaceutical Investigation
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• v.31 no.2
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• pp.89-94
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• 2001

The pharmacokinetics of recombinant human granulocyte colony stimulating factor (rhG-CSF) following intravenous (i.v.), intramuscular (i.m.) and subcutaneous (s.c.) administration of HM1041l-lyo and HM10411-liq (lyophilized and liquid formulations of rhG-CSF, recently under development by Hanmi Pharmaceutical Company) were studied in rats, and compared with that of Filgrastim (conventional formulation of rhG-CSF on market). The plasma concentration of rhG-CSF was quantified using a specific ELISA. The pharmacokinetic parameters of rhG-CSF, after i.v., i.m. and s.c. administration of Filgrastim, HM1041l-lyo and HM1041l-liq to rats at a rhG-CSF dose of $10\;{\mu}g/kg$, were almost identical among the three formulations. No dose-dependency was observed in the pharmacokinetic parameters of rhG-CSF following i.v. administration in the dose range of $5{\sim}100\;{\mu}g/kg$. rhG-CSF, after i.v. administration of the three preparations at a dose of $10\;{\mu}g/kg$ to rats, was detected at low levels in all of the body tissues with highest tissue/plasma ratio of $0.46{\sim}0.51$ for the kidney at 30 min after the administration. The pharmacokinetics of rhG-CSF, after i.v. administration to mice at a dose of $10\;{\mu}g/kg$, were comparable among the three formulations. In conclusion, HM10411-lyo and HM10411-liq exhibited similar pharmacokinetics for rhG-CSF with Filgrastim regandless of animal species. Considering the fact that HM10411 series, contrary to Filgrastim, are proteins lacking a methionine residue, the methionine moiety in rhG-CSF molecule does not appear to influence the pharmacokinetics of the protein significantly.

• Microbiology and Biotechnology Letters
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• v.32 no.2
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• pp.135-141
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• 2004

Human granulocyte colony-stimulating factor (hG-CSF) is a hematopoiesis agent that principally affects the differentiation of neutrophils in the bone marrow. At present, recombinant hG-CSF is used successfully in the treatment of chemotheraphy-induced neutropenia and its indication has been expanded to bone marrow transplantation and aplastic anemia. In this study, we have constructed rhG-CSF secretion plasmid pYRC1 in which OmpA signal sequence/hG-CSF gene was expressed under the control of the T7 promoter. rhG-CSF produced in E. coli BL21 (pYRC1) grown at $37{\circ}C$ was found in aggregates. However, 15% of the periplasmic protein was soluble rhG-CSF when the E. coli BL21 (pYRC1) was cultured at $25^{\circ}C$ for 7 h in the modified MBL medium containing 10 g/$\ell$ glucose with 10 $\mu$M IPTG induction. The production of soluble rhG-CSF in E. coli BL21 (pYRC1) using fed batch culture was also studied. In the fed batch culture system, the final yield of rhG-CSF produced from E. coli BL21 (pYRC1) was increased from 4.4 mg/$\ell$to 24 mg/$\ell$by controlling the specific growth rate from $0.43 h^{-1}$ to $0.14 h^{-1}$, and optimizing the time of induction.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.50 no.9
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• pp.657-662
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• 2022

In this paper, the calculation using simulation and two measurement methods for G/T of the telemetry are analyzed. Antenna gain and noise temperature are calculated by using ICARA and Antenna Noise Temperature Calculator. System G/T were calculated by using Antenna gain/noise temperature, LNA gain/noise temperature, cable loss. The first G/T measurement method is Y-factor measurement method, which is to calculate G/T by comparing LNA noise temperature and a signal level difference when an antenna and a 50ohm termination are respectively connected to an LNA input terminal Second method is Solar calibration measurement method that is to calculate G/T by comparing noise level difference when looking at the sun and lowest level point. Finally, the accuracy was reviewed by comparing the G/T calculation results with the two measurement methods, and the optimal measurement method according to antenna performance and operating environment was presented.

• Biomolecules & Therapeutics
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• v.2 no.3
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• pp.281-285
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• 1994

Neutropenia is a major dose-limiting factor in cancer chemotherapy diminishing its usefulness and increase patient's susceptibility to infectious disease. Some recombinant human granulocyte colony stimulating factors(rhG-CSFs) are in use to reduce the risk of this serious side effect. In this study, we examined the pharmacological properties of DA-3030, a rhG-CSF expressed in E. coli. DA-3030 100 and $\mu\textrm{g}$/kg, i. v., had no significant effect on the central nervous, gastrointestinal system in mice and cardiovascular system in rabbits, but it slightly inhibited the spontaneous motility of isolated nonpregnant uterus in rats. It also had no influence on excretion of urinary electrolytes. DA-3030 administered for successive 3 days increased the blood WBC count in zymosan air pouch inflammed rats and in normal rats. These results indicate that DA-3030 has little side effects in animals.

• Journal of the Korean Mathematical Society
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• v.54 no.1
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• pp.117-139
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• 2017

This paper presents a systematic study for theoretical aspects of a unified approach to the abstract relative Fourier transforms over canonical homogeneous spaces of semi-direct product groups with Abelian normal factor. Let H be a locally compact group, K be a locally compact Abelian (LCA) group, and ${\theta}:H{\rightarrow}Aut(K)$ be a continuous homomorphism. Let $G_{\theta}=H{\ltimes}_{\theta}K$ be the semi-direct product of H and K with respect to ${\theta}$ and $G_{\theta}/H$ be the canonical homogeneous space (left coset space) of $G_{\theta}$. We introduce the notions of relative dual homogeneous space and also abstract relative Fourier transform over $G_{\theta}/H$. Then we study theoretical properties of this approach.

• Journal of the Korean Magnetics Society
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• v.20 no.3
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• pp.120-128
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• 2010

Electron spin resonance (ESR) is one of an experimental choice for studying magnetic materials that have one or more unpaired electrons. ESR spectroscopy finds its wide applications in branches of science encompassing physics, chemistry, biology, medicine and quantum computation. In this brief review we introduce a basic principle of ESR and describe how to extract information on g-factor, spin and orbital states from the ESR spectral parameters. Finally, several examples are discussed with an intention to have a practical feeling of what ESR can do in magnetism.

• Journal of the Korea Safety Management & Science
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• v.16 no.3
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• pp.421-432
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• 2014

This study is intended to analyze the relation between G. D. Weisman's Way finding 4 elements the accessibility and efficiency of consumers as to eternal area for Seoul historical museum. The findings are summarized as the following three aspects. First, G. D. Weisman's Way finding element introduced in this study had a significant impact on visitor satisfaction.. It leads to the following conclusion: The higher the impact is, the greater accessaccessibility and efficiency are. Second, among 4 elements, the factor that had the biggest impact on the accessibility was 'visual-perceptual accessibility'. Thus, 'visual-perceptual accessibility' should be considered first to boost the accessibility to consumers. Third, among 4 elements, the factor that had the biggest impact on the efficiency was 'sign system'. Thus, 'sign system' should be considered first to boost the efficiency to consumers.