• 보건행정학회지
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• 제27권4호
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• pp.276-283
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• 2017

Background: Electronic cigarette (e-cigarette) has rapidly increased. Even though e-cigarettes are actually not smoking cessation alternative supplies, some people perceive them as smoking cessation alternative supplies. The purpose of this study is to identify the relationship between e-cigarette experiences and smoking cessation behaviors among Korean adults. Methods: Cross-sectional data was collected from 7,550 participants of Korea National Health and Nutrition Examination Survey in 2014. A total of 867 participants who were current smokers were enrolled in this study. Multi-variable logistic regression analysis were performed to identify the relationship between the smoking cessation behavior and the e-cigarette experience. Results: The e-cigarette experience rate of current smokers was 22.1%. The e-cigarette experience rate was higher in groups with the higher income, the higher education level, and the white collar jobs. Smokers with experience of smoking cessation (odds ratio [OR], 3.03; 95% confidence interval [CI], 1.67 to 5.76) and with intention to smoking cessation in the future (OR, 1.59; 95% CI, 1.05 to 2.43) were more likely to experience the e-cigarette. Especially, smokers who used smoking cessation alternative supplies were more likely to experience the e-cigarette than smokers who did not use it (OR, 2.87; 95% CI, 1.59 to 5.18). Conclusion: We confirmed that e-cigarette experiences were associated with smoking cessation experience, smoking cessation plan, and use of smoking cessation aid among smokers in Korea. Additional studies should be continued to confirm whether e-cigarette are continuously influencing the smoking cessation of current smokers in South Korea as one of the smoking cessation alternative supplies.

• 폴리머
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• 제37권4호
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• pp.411-419
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• 2013

다양한 생체재료들이 이식용 인공장기나 의료용 장비로 폭넓게 사용되고 있으나 혈액과 접촉하는 경우가 많아짐으로써 발생되는 혈전의 문제로 인해 이식재와 혈액간의 혈액 친화성의 향상이 연구자들에게 관심의 대상이 되고 있다. 연잎의 표면구조는 항 오염 특성이라는 측면에서 많은 연구가 진행되어 왔으며, 산업적인 용도로 적용하고자 하는 주된 시도들이 있어 왔다. 대부분 주형법이나 졸-젤 방법, 층 쌓기 방법 등을 포함한 다양한 기법으로 표면처리를 함으로써 인위적인 모사가 가능해 왔다. 최근에 들어 이러한 표면의 초소수성 성질이 의료용 재료의 표면처리 기법으로써 혈관 이식재에서부터 항 박테리아용 표면에까지 널리 적용하려는 시도가 진행되고 있다. 본 리뷰논문에서는 최근 많이 사용되는 연잎 구조로의 표면처리 기법들을 중심으로 요약하였으며, 이들을 이용한 의료분야로의 적용 시도들을 정리하고자 하였다.

• BMB Reports
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• 제52권6호
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• pp.397-402
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• 2019

Middle East respiratory syndrome coronavirus (MERS-CoV) uses the spike (S) glycoprotein to recognize and enter target cells. In this study, we selected two epitope peptide sequences within the receptor binding domain (RBD) of the MERS-CoV S protein. We used a complex consisting of the epitope peptide of the MERS-CoV S protein and CpG-DNA encapsulated in liposome complex to immunize mice, and produced the monoclonal antibodies 506-2G10G5 and 492-1G10E4E2. The western blotting data showed that both monoclonal antibodies detected the S protein and immunoprecipitated the native form of the S protein. Indirect immunofluorescence and confocal analysis suggested strong reactivity of the antibodies towards the S protein of MERS-CoV virus infected Vero cells. Furthermore, the 506-2G10G5 monoclonal antibody significantly reduced plaque formation in MERS-CoV infected Vero cells compared to normal mouse IgG and 492-1G10E4E2. Thus, we successfully produced a monoclonal antibody directed against the RBD domain of the S protein which could be used in the development of diagnostics and therapeutic applications in the future.

• 한국산학기술학회논문지
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• 제15권3호
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• pp.1478-1488
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• 2014

본 연구는 외국인 의료관광객을 대상으로 의료관광 만족에 영향을 줄 수 있는 특성요인을 찾는데 있다. 의료관광 민족에 영향을 미치는 요인을 파악하기 위해 대상자의 특성에서 유의한 차이를 나타낸 변수들을 가능한 영향요인으로 선정하여 분석한 결과에서는 전체여행 예산, 의료서비스를 위한 방문 횟수, 직업(자영업), 학력(대학 졸업 이상), 월평균 가구 소득, 의료비 예산, 방문기간이 유의한 영향 요인으로 나타났다. 이러한 영향요인들이 대상자의 의료관광 만족을 43.5% 설명하였으며, 가장 높은 영향요인은 전체여행 예산으로 나타났다. 의료관광 만족이 구전의사와 재방문의도에 미치는 영향력을 예측하기 위한 분석결과에서는 의료관광 만족요인이 구전의사와 재방문의도에도 유의한 예측 영향요인으로 나타났다. 즉 의료관광 만족이 1단위 높을수록 구전의사가 있을 확률은 없을 확률보다 1.57배 높았고, 재방문의도가 있을 확률은 없을 확률보다 1.85배 높았다.

• 의학교육논단
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• 제18권2호
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• pp.58-64
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• 2016

The birth of the scientific revolution, brought forth by Vesalius and Copernicus in 1543, marked the beginning of a new age. However, the changes such as treatment effectiveness, survival rate, prevalence of specific diseases, etc. had not yet become clear during the 16th century. In the early 17th century, Boerhaave emphasized bedside teaching and practice. His attitude influenced numerous students and educators, so many medical students visited hospital wards where he worked. From the late 18th to 19th centuries, Jenner's smallpox vaccination, Pasteur's anthrax and rabies vaccinations, and Koch's four postulates used to detect pathogens were developed using the scientific research method, which initiated big changes for medicine. Flexner, credited for reporting the new medical education system, adopted scientific medicine. He believed medical students must study basic medical science since it could be the foundation of clinical medicine and lead to a revolution in the field. He proposed a new medical curriculum composed of two-years of basic medicine and two-years of clinical medicine, which has been used more than 100 years. During the late 20th century, bedside teaching rounds decreased gradually as scientific medicine has become popular. Many medical educators in many articles have proposed bedside education as an effective method for medical learning. Despite the advent of the age of artificial intelligence and the changing of medical environments in the near future, bedside education will be more useful and important for medical students, educators, and patients as it is a traditional method and essential for patients who desire a more personal approach.

• 대한임상검사과학회지
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• 제55권3호
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• pp.203-212
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• 2023

코로나19가 창궐한 후 임상병리사(medical technologists, MT)가 병원에서 PCR 검사를 수행하고 있을 뿐만 아니라 차세대 염기서열분석(next-generation sequencing, NGS)도 수행한다는 사실을 일반적으로 알고 있다. 하지만, 많은 사람들은 유전자검사 분야에 대한 임상병리사의 업무로 의료법에 명시되어 있지 않다는 사실을 인지하지 못하고 있는 실태이다(MT 72.5%, N=200; 학생 62.8%, N=123). 이러한 이유로, NGS에 대한 임상병리사의 업무 적절성을 검증하기 위해서 온라인 설문지를 작성하도록 설계하여 설문조사 결과를 분석하였다. NGS가 포함된 유전분야에 대한 임상병리사의 업무범위에 대한 법제화가 필요하다(MT 99.5%, N=200, 학생 86.8%, N=123)고 나타났다. 그리고 임상병리사 국가면허시험 문제은행에 세포유전학 및 분자유전학 관련 임상유전학 문항이 모두 포함돼야 한다(MT 97.5%, N=200; 학생 72.3%, N=123)고 조사되었다. 이러한 조사를 바탕으로 임상병리학 분야의 발전을 위해 임상병리사와 학생 모두를 위한 유전자 교육 및 법제화를 위해 대한임상병리사협회는 교수협의회와 적극 협력할 필요가 있겠다.

• Physical Therapy Rehabilitation Science
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• 제9권1호
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• pp.10-17
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• 2020

Objective: Hallux valgus (HV) is a common musculoskeletal deformity that is accompanied with pain and continues to decrease one's quality of life and ability to perform daily life activities by affecting gait and static stability. Therefore, this study aimed to investigate the effect of the angle of HV (HVA) and to compare the one-legged stance and gait parameters in young adults with less HV and severe HV. Design: Cross-sectional study. Methods: Forty young adults were divided into two groups, where HVA ≥15° (n=20) was defined as HV, and HVA <15° (n=20) was defined as normal. For balance ability, the center of pressure (COP) path, velocity, length of axis of the COP path, deviation of the x-axis and y-axis, and percentage of foot pressure were measured, and gait, the foot rotation angle, step length, percentage of each phase of the gait cycle, time change from the heel to forefoot, and maximum pressure of the forefoot and midfoot were measured. Results: Significant differences were found in sway length and time change from heel to forefoot during walking between the normal and HV groups (p<0.05). Most parameters were not associated with the HVA, but parameters such as length of axis and time to change from heel to forefoot were significantly associated with the HVA (p<0.05). Conclusions: These results suggest that most one-legged stance and gait parameters were not significantly affected by the HVA in young adults; therefore, future studies are needed in order to address other dynamic parameters and other methods of gait analysis for detecting clinically meaningful conditions.

• Journal of Yeungnam Medical Science
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• 제39권1호
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• pp.31-38
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• 2022

Background: To prepare for future work stoppages in the medical industry, this study aimed to identify the effects of healthcare worker strikes on the mortality rate of patients visiting the emergency department (ED) at six training hospitals in Daegu, South Korea. Methods: We used a retrospective, cross-sectional, multicenter design to analyze the medical records of patients who visited six training hospitals in Daegu (August 21-September 8, 2020). For comparison, control period 1 was set as the same period in the previous year (August 21-September 8, 2019) and control period 2 was set as July 1-19, 2020. Patient characteristics including age, sex, and time of ED visit were investigated along with mode of arrival, length of ED stay, and in-hospital mortality. The experimental and control groups were compared using t-tests, and Mann-Whitney U-test, chi-square test, and Fisher exact tests, as appropriate. Univariate logistic regression was performed to identify significant factors, followed by multivariate logistic regression analysis. Results: During the study period, 31,357 patients visited the ED, of which 7,749 belonged to the experimental group. Control periods 1 and 2 included 13,100 and 10,243 patients, respectively. No significant in-hospital mortality differences were found between strike periods; however, the results showed statistically significant differences in the length of ED stay. Conclusion: The ED resident strike did not influence the mortality rate of patients who visited the EDs of six training hospitals in Daegu. Furthermore, the number of patients admitted and the length of ED stay decreased during the strike period.

• 간호행정학회지
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• 제18권2호
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• pp.189-201
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• 2012

Purpose: The purpose of this study was to explore the use of outcome indicators and perception of outcome evaluation of oncology advanced practice nurses (APNs). Method: A total of 111 oncology APNs from hospitals which have over 400 beds were surveyed. The participants' use of outcome indicators and perception of outcome evaluation were collected using a questionnaire including 84 outcome indicators for APNs developed by Sung et al. and 13 items on APNs' contribution to the hospitals developed by Kleinpell (2005). Data were analyzed using descriptive statistics, t-test, and $x^2$ test. Result: Twelve items out of 84 outcome indicators were used over 50% of the time and 57 items could be used in the future by the participants. Seven of the 10 top-ranking outcome indicators in use were education related and were also expected to be used frequently in the future. The score for participants' perception of outcome evaluation was average-high, 3.82 out of 5. Conclusions: The results of the study show that the main outcome indicator for oncology APNs is education related, and thus the use of education related outcome indicators is recommended to make oncology APNs' activities be more visible.

• Physical Therapy Rehabilitation Science
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• 제10권3호
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• pp.379-386
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• 2021

Objective: The purpose of this study was to systematically review the trunk impairment scale that are used to assess the trunk control of stroke patients. Design: A systematic review Methods: Stroke subjects were categorized as acute, subacute, chronic. In this systematic review, the studies published between 2000 and 2020 were selected. A literature search using the keywords 'QUADAS', 'stroke', 'trunk impairment scale'. Data sources included RISS, GOOGLE Scholar and DBpia. We assessed the quality of assessment tools using Quality Assessment of Diagnostic Accuracy Studies tool. Results: We reviewed 18 studies. 7 of the 18 studies reported reliability results, 10 reported validity results. The QUADAS tool quality evaluation of 17 literatures extracted except for one randomized control test among 18 literatures showed a range of 3 to 13 points. 5 of the 18 studies are presented with the Cronbach alpha coefficient indicating reliability using internal consistency, all of which are more than 0.8. All studies that presented test-retest reliability, intra-rater reliability, and inter-rater reliability showed high agreement with an intra-class correlation coefficient of 0.75 or more. Conclusions: A systematic review of the study of the application of the trunk impairment scale for stroke patients will help provide criteria for future studies and application of the trunk impairment scale in clinical practice.