• Proceedings of the Korean Society for Applied Microbiology Conference
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• 1975.12a
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• pp.183.3-183
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• 1975

1) 목적 : Furfural는 복소환식화합물중 오원환으로써 자연계에 널리 분포되고 있다. 공업적으로 중요한 Aldehyde로써 근대공업화학에 새로운 공해요인이 되고 있고 발효생산물에도 널리 존재하는 Furan 환화합물의 생물적 개열 대해선 거의 보고된 바가 없다.(중략)

• Bulletin of the Korean Chemical Society
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• v.24 no.12
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• pp.1832-1834
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• 2003

• Proceedings of the Korean Vacuum Society Conference
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• 2007.08a
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• pp.379-379
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• 2007

• Bulletin of the Korean Chemical Society
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• v.8 no.1
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• pp.59-60
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• 1987

• Archives of Pharmacal Research
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• v.27 no.4
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• pp.381-385
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• 2004

Nine phenolic ($1\~9$) and two furan type (10, 11) compounds, were isolated from the methanolic extract of the tuber of Gastrodia elata Blume (Orchidaceae) in the course of continuing search for platelet anit-aggregating plant components. Compound 1 was identified as 4,4'-dihy-droxybenzyl sulfone, a novel compound for the best of our knowledge. Compound 10, 5-hydroxymethyl-2-furancarboxaldehyde, was isolated for the first time from this plant. Compound 1 ($IC_{50};\;83{\mu}M$) was about four times more inhibitory to U46619 induced aggregation than ASA ($IC_{50};\340{\mu}M$). Compound 9, 4,4'-dihydroxy-dibenzylether, ($IC_{50};\;5{\mu}M$, $3{\mu}M\;and\;33{\mu}M$, respectively) was $10\~}80$ fold more potent than ASA ($IC_{50};\;420\;{\mu}M,\;53\;{\mu}M\;and\;340\;{\mu}M$ respectively) to collagen, epinephrine and U46619 induced aggregation, although it is less active than ASA to AA induced aggregation.

• Journal of Korean Society for Atmospheric Environment
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• v.11 no.E
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• pp.13-21
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• 1995

This Pilot study identifies potential dioxin and furan sources and medical plastic wastes produced from hospital solid waste streams. In this study, air emissions of dioxins and furans from sources in the U.S., which were estimated by the U.S. Environmental Protection Agency (EPA), were summarized. Potential loading routes of dioxins and furans to the U.S.-Canada Great Lakes region have also been identified in trcent surveys. In addition, medical and hospital solid wastes produced in typical large city hospitals were characterized as important potential sources of dioxins and furans. Plastic contents in medical Plastics Characterization Survey (MMPCS), plastics composition data were obtained from a survey of five Massachusetts Hospitals and Medical Centers. By identifying plastic wastes as a percentage of total hospital wastes, we were able to use data from a preliminary study that analyzed the waste stream of 16 major New York City hospitals (NYCMWS) characterizing the plastic content of the wasters. This study determined the types of plastic wastes included in each medical waste stream (regulated medical waste or non regulated medical waste) and it discussed the potential for recyclibility of hospital plastic wastes. The combination of the NYCMWS and the MMPCS surveys provides for the first overview of the size of the recycling task of hospital plastic wastes and the potential of dioxin elimination if dioxin generating plastics were to be eliminated from hospital use.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.5
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• pp.365-369
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• 2014

Cedrus deodara (Pinaceae) has been used traditionally in Ayurveda for the treatment of central nervous system disorders. 3,4-bis(3,4-dimethoxyphenyl)furan-2,5-dione (BDFD) was isolated from heart wood of Cedrus deodara and was shown to have antiepileptic and anxiolytic activity. Thus, the present study was aimed to explore its anti-depressant effect and to correlate the effect with serotonin and nor adrenaline levels of brain. Albino mice were used as experimental animal. Animals were divided in to three groups; vehicle control, imipramine (30 mg/kg i.p.), BDFD (100 mg/kg i.p.). Tail suspension test (TST) and forced swim test (FST) was performed to evaluate antidepressant effect of BDFD. BDFD (100 mg/kg, i.p.) showed a significant decrease in immobility time when subjected to FST whereas immobility time was not significantly altered in TST. BDFD treatment increased serotonin and noradrenaline levels in the brain which is indicative of BDFD having possible atypical antidepressant action.

• Bulletin of the Korean Chemical Society
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• v.33 no.8
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• pp.2623-2626
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• 2012

A series of functionalized furans were synthesized by way of a palladium-catalyzed coupling reaction of 2,3,5-trisubstituted furans with aryl chlorides through C-H bond cleavages at C-4 position. The feature of the reaction was facilitative preparation of furan derivatives with good functional group tolerance. All reactions gave the desired products in moderate to good yields in the presences of $BuAd_2P$ and t-BuOK in DMF at $120^{\circ}C$ after 15 h.

• Journal of Microbiology and Biotechnology
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• v.22 no.11
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• pp.1482-1485
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• 2012

A natural furan derivative was isolated from the methanolic extract of the fruit bodies of Fomitiporia ellipsoidea. Its chemical structure was elucidated as methyl 3,5-dioxo-1,3,5,7-tetrahydrobenzo[1,2-c:4,5-c']difuran-4-carboxylate by means of extensive NMR and MS data analysis, and named as fomitiporiaester A (1). Compound 1 showed significant antitumor activity to hepatoma $H_{22}$ in vivo, and the inhibition rates were 42.94%, 49.17%, and 58.15% at concentrations of 5, 10, and 20 mg/kg, respectively. Compound 1 showed weak cytotoxic activities against the human hepatoblastoma (HepG-2) and human oophoroma (Skov 3) cell lines with$IC_{50}$ values of more than $100{\mu}M$.

• Analytical Science and Technology
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• v.9 no.4
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• pp.399-405
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• 1996

The flavor compounds of the oil from roasted sesame seeds were collected by simultaneous steam distillation/ extraction(SDE) and dynamic headspace sampling(DHS) and were analyzed using a gas chromatograph equipped with a flame ionization detector and connected into a mass spectrometer. Among the flavor compounds collected by the SDE method, 46 compounds were identified. They consisted of 6 alcohols, 6 aldehydes, 5 ketones or acids, 4 furans or phenols, 12 pyrazines, 4 pyridines or thiazoles, and others. Thirty six compounds were identified by DHS and many of them were the same as those identified by the SDE method. However, some compounds such as 1-hexanol, pentanal, and dimethylsulfide were identified only by the DHS method.