• 제목/요약/키워드: functional region

검색결과 999건 처리시간 0.024초

요부-골반-고관절 복합체의 생체역학 -천장관절 기능부전과 관련하여- (Integrated Biomechanics in the Lumbo-Pelvic-Hip Complex : Focus on Sacroiliac Joint Dysfunction)

  • 윤홍일;심현보;이준용
    • 대한정형도수물리치료학회지
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    • 제19권1호
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    • pp.69-77
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    • 2013
  • The pelvic girdle function as an integrated unit with all three bones moving at all three joints, are influenced by the lower extremities below and vertebral column and trunk above sacroiliac movements are caused by spinal motion, whereas iliosacral movements are caused by movements of the lower limbs. Concept of normal functional integration among the lumbar spine, pelvic and hip joint is basic to the understanding of dysfunction in this region and also functional movement of the lumbo-pelvic-hip region are part of the clinical examination, consequently the integrated biomechanics of these region need to be understood. The purpose of this review is to ascertain the integrated biomechanics among the lumbo-pelvic-hip complex by consideration of literature and to give sufficient information to be able to render accurate assessment and treatment for the syndromes described.

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Functional Dissection of Sigma-like Domain in Antibiotic Regulatory Gene, afsR2 in Streptomyces lividans

  • Kim Chang-Young;Park Hyun-Joo;Kim Eung-Soo
    • Journal of Microbiology and Biotechnology
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    • 제16권9호
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    • pp.1477-1480
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    • 2006
  • The 63-amino-acid-encoding afsR2 is a global antibiotics-stimulating regulatory gene identified from the chromosome of Streptomyces lividans. To dissect a putative functional domain in afsR2, several afsR2-derivative deletion constructs were generated and screened for the loss of actinorhodin-stimulating capability. The afsR2-derivative construct missing a 50-bp C-terminal region significantly lost its actinorhodin-stimulating capability in S. lividans. In addition, site-directed mutagenesis on amino acid positions of #57-#61 in a 50-bp C-terminal region, some of which are conserved among known Sigma 70 family proteins, significantly changed the AfsR2's activity. These results imply that the C-terminal region of AfsR2 is functionally important for antibiotics-stimulating capability and the regulatory mechanism might be somehow related to the sigma-like domain present in the C-terminal of AfsR2.

A Novel Approach for Object Detection in Illuminated and Occluded Video Sequences Using Visual Information with Object Feature Estimation

  • Sharma, Kajal
    • IEIE Transactions on Smart Processing and Computing
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    • 제4권2호
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    • pp.110-114
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    • 2015
  • This paper reports a novel object-detection technique in video sequences. The proposed algorithm consists of detection of objects in illuminated and occluded videos by using object features and a neural network technique. It consists of two functional modules: region-based object feature extraction and continuous detection of objects in video sequences with region features. This scheme is proposed as an enhancement of the Lowe's scale-invariant feature transform (SIFT) object detection method. This technique solved the high computation time problem of feature generation in the SIFT method. The improvement is achieved by region-based feature classification in the objects to be detected; optimal neural network-based feature reduction is presented in order to reduce the object region feature dataset with winner pixel estimation between the video frames of the video sequence. Simulation results show that the proposed scheme achieves better overall performance than other object detection techniques, and region-based feature detection is faster in comparison to other recent techniques.

Locus Control Region의 구조와 기능 (The Structure and Function of Locus Control Region)

  • 김애리
    • 생명과학회지
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    • 제17권11호
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    • pp.1587-1592
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    • 2007
  • Locus control region (LCR) is a cia-acting element which regulates the transcription of genes in developmental stage and/or tissue-specific pattern. Typically, LCR consists of several DNase I hypersensitive sites (HSs), where the binding motifs for transcriptional activators are present. The binding of activators to the HSs recruits chromatin modifying complexes to the LCR, opening chromatin structure and modifying histones covalently through the locus. LCR forms close physical contact with target gene located at a distance by looping away intervening region. In addition, non-coding RNA is transcribed from LCR toward target genes in continuously acetylated active domain. These structural and functional features of LCR suggest that the LCR plays many roles in chromatin activation and transcriptional regulation.

전라북도 가로시설물의 디자인 제고를 위한 연구 (A Study on the Design Improvement of Street Facilities in Jeollabuk-do Province)

  • 김상현;김홍배
    • 한국농촌건축학회논문집
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    • 제25권2호
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    • pp.1-8
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    • 2023
  • This study reveals the absence of standard design guidelines by region through investigation and analysis centered on public design cases by region in Jeollabuk-do and design elements that can reflect the integration, identity, and diversity of public design in each region by five regions. Through this, the following conclusions could be obtained. First, to improve the quality of street facilities in Jeollabuk-do, the design elements (design motif, color, pattern) applicable to the standard design were analyzed by dividing them into five regions. As a design motif, it was possible to extract patterns containing straight lines, sophistication, dignity, and smartness. In the Northeast region, it is comfortable with the motif of the mountain ridge reflecting geographical characteristics, and it can be extracted elements that contain warm and natural colors. In the southeastern region, patterns that reflect design elements were extracted by applying safe, lively, and peaceful colors with the design motif of curves that blend nature and agriculture. In the southwestern region, design pattern elements that highlight nature, history, and culture were extracted with various cultural assets and natural greenery as motifs. Lastly, in the Saemangeum region, the ocean flow and greenery could be used as a design motif to reflect a positive, clear, future-oriented image in the design spot zones by region. Second, based on the standard design elements (design motive, color, pattern) by region extracted for the standard design development of street facilities in each region in Jeollabuk-do, an integrated zone(Form, structure, material, color, functional element) to which regional design guidelines can be applied. Third, an integrated zone (form, structure, material, color, functional elements) was composed. In addition, design spot zones (patterns and colors in city and county units) that can contain the diversity and identity of each region were designated. By designating design spot zones (patterns and colors in city and county units) that can contain the diversity and identity of each region, standard design development plans (integrated pillars, jaywalking prevention fences, roundabouts (urban type, rural type), street trees) Eight standard designs, including protective covers, street planters, flat benches, light benches, visual media for user guidance, and parking zones for personal mobile devices) were presented.

The Function of Multiple Pribnow Box on the Aerobic-Anaerobic Switch Control of aeg-46.5 Gene Expression

  • 강인오;정연주;최무현
    • Bulletin of the Korean Chemical Society
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    • 제22권8호
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    • pp.903-908
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    • 2001
  • The gene aeg-46.5, which is expressed under anaerobic condition, has putative triple -10 regions and four transcription start sites. The mRNA transcription level and its start point change depending on the aerobic/anaerobic growth condition. RNA polymerase and its regulatory proteins must choose which of three -10 region to use. The putative triple 10 region was mutated to make only one of them function with consensus -10 region sequence (TATAAT) and the other two as non-functional region. The results show that the second and third -10 regions are used for the aerobic/anaerobic expression. The third -10 region is responsible for the high aerobic to anaerobic switch ratio. This suggests that only the last two of the putative triple -10 region have functions on aeg-46.5 gene expression switch control. The phenotype of the mutated promoter was tested in the wild type cell and narL - cell. The results indicate that the control by NarL is independent from the selection of -10 region. The expression patterns on multi-copy plasmids and on single-copy chromosome were compared. These results show that the aerobic/anaerobic switch control of aeg-46.5 is through the choice of -10 region. The mechanism of choosing different -10 region remains to be seen.

섭식연하장애의 이해와 실제 (Understanding and Practice of Eating-Swallowing Disorder)

  • 소종섭;고석민
    • 대한치과의사협회지
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    • 제56권5호
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    • pp.287-295
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    • 2018
  • Eating-swallowing disorder (dysphagia) is a very important functional problem for the elderly, and it has a significant impact on the quality of their life. Because the eating and swallowing processes are affected by oral tissues including teeth, tongue, and oral muscles, it is natural that the dentist as a specialist in oro-facial region, intervenes in the diagnosis and treatment of the disorder. Nevertheless, Korean dentists still lack interest and understanding of dysphagia. In aged society, it is necessary that the dentists understand the functional disorders as well as oral diseases. The purpose of this study is to introduce the evaluation and treatment methods of eating and swallowing functional disorders in order to cope with eating-swallowing disordered patients who are frequently encountered in aged society.

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Brain Mapping Using Neuroimaging

  • Tae, Woo-Suk;Kang, Shin-Hyuk;Ham, Byung-Joo;Kim, Byung-Jo;Pyun, Sung-Bom
    • Applied Microscopy
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    • 제46권4호
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    • pp.179-183
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    • 2016
  • Mapping brain structural and functional connections through the whole brain is essential for understanding brain mechanisms and the physiological bases of brain diseases. Although region specific structural or functional deficits cause brain diseases, the changes of interregional connections could also be important factors of brain diseases. This review will introduce common neuroimaging modalities, including structural magnetic resonance imaging (MRI), functional MRI (fMRI), diffusion tensor imaging, and other recent neuroimaging analyses methods, such as voxel-based morphometry, cortical thickness analysis, local gyrification index, and shape analysis for structural imaging. Tract-Based Spatial Statistics, TRActs Constrained by UnderLying Anatomy for diffusion MRI, and independent component analysis for fMRI also will also be introduced.

벼 줄무의잎마름병의 새로운 중간기주 '들묵새' (New Alternate Host of Rice stripe virus - 'Deulmuksae')

  • 윤영남;이봉춘;정지훈;김정인;황재복;김창석;홍성준;강항원;송석보;홍연규;박성태;이기운
    • 식물병연구
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    • 제15권2호
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    • pp.63-67
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    • 2009
  • 벼 줄무의잎마름병은 Tenuivirus 그룹에 속하며, 애멸구가 매개하는 바이러스병으로 우리나라에서는 2001년, 2007년 대발생한 보고가 있다. 벼 줄무의잎마름병의 중간기주조사를 위하여 2008년 3월부터 9월까지 전국 13지역 26지점의 논 주위 발생 잡초 15과 50종을 채집하였다. 보리, 뚝새풀, 들묵새, 잠자리피, 돌피, 바랭이에서 벼 줄무의잎마름병의 이병을 확인하였다. 들묵새는 가을에 발아하여 봄에 고사하는 겨울나기 외래잡초로 현재 녹비 및 피복작물로 많이 사용되고 있다. 들묵새의 지역별 이병률조사를 위하여 2008년 6월 부안군 계화면 시료 111주, 서천군 마서면 시료 50주를 ELISA한 결과 부안군은 32주가 감염이 확인되어 28.8%의 이병률을, 서천군은 8주가 감염이 확인되어 16.0%의 이병률을 확인할 수 있었다. 현재까지 들묵새의 벼 줄무의잎마름병의 감염에 관련된 보고가 없었으며, 이 논문에서 벼 줄무의잎마름병의 중간기주로 들묵새를 최초 보고한다.