• Title/Summary/Keyword: functional interaction

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Electronic and Magnetic Structure Calculations of Cubane-type Co4 Magnetic Molecule (Cubane 구조를 가진 Co4 분자자성체의 전자구조 및 자기구조계산)

  • Park, Key Taeck
    • Journal of the Korean Magnetics Society
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    • v.27 no.4
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    • pp.140-144
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    • 2017
  • We have studied electronic and magnetic structure of cubane-type Co magnetic molecule using density functional method. The calculated density of states show $Co^{+2}$ ionic state and high-spin state because of large exchange interaction between inside Co 3d electrons. The exchange interaction J between Co atoms depends Co-O-Co angle. The calculated J is ferromagnetic with right angles. On the other hand J is antiferromagnetic with large angles since super-exchange interactions between $Co^{+2}$ atoms. It induces that Co cubane has a antiferromagnetic spin structure of AFM1 = [${\uparrow}{\uparrow}{\downarrow}{\downarrow}$]

Electronic and Magnetic Structure Calculations of Cubane-type Mn4 Cluster (Cubane-type Mn4 클러스터의 전자구조 및 자기구조 계산)

  • Park, Key-Taeck
    • Journal of the Korean Magnetics Society
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    • v.22 no.4
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    • pp.121-124
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    • 2012
  • We have studied electronic and magnetic structure of cubane-type Mn4 cluster using OpenMX method based on density functional method. The calculated density of states shows that the octahedron of O atoms split $e_g$ and $t_{2g}$ energy levels like bulk MnO with cubic structure. Total energy with antiferromagnetic spin configuration is lower than those of other spin configurations because of super exchange interaction. Calculated exchange interaction J between Mn atoms with anti-parallel spin is larger than between Mn atoms with parallel spin.

Research and Design of Functional Requirements of Shared Electric Bicycle App Based on User Experience

  • Xiangqin Zhao;Bin Wang
    • Journal of Information Processing Systems
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    • v.19 no.2
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    • pp.219-231
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    • 2023
  • Intelligent applications are crucial for increasing the popularity of shared urban electric bicycles (EBs). Building an application platform architectural system that can satisfy independent user operations is critical for increasing the intelligent usage of shared EBs. Consequently, we collected online reviews of shared EB applications, conducted semantic processing and sentiment analysis, and refined the positive and negative review data for each function. The positive and negative review indices of each function were calculated using the formulae for positive and negative review indices of product functions, thereby determining the functions that need to be improved. Each function of the Shared EB application was improved according to its business process. The main contributions of this study are to build a user requirement architecture system for the Shared EB application with five dimensions and 22 functions using the Delphi method to design the user interface (UI) of this application based on user satisfaction evaluation results; to create a high-fidelity dynamic interaction prototype and compare user satisfaction before and after improving the Shared EB application functions. The testing results indicate that the changes in the UI significantly improve the user experience satisfaction of the urban Shared EB application, with the positive experience index increasing by 69.21% and the negative experience index decreasing by 75.85% overall. This information can be directly used by relevant companies to improve the functions of the Shared EB application.

Proposal on the Enhancement of Real-time Processing and Interaction in a Camera-tracked Laser Pointer System (카메라 추적 기반 레이저 포인터 시스템의 실시간 처리와 상호작용 개선을 위한 제안)

  • Lim, Jong-Gwan;Sohn, Young-Il;Sharifi, Farrokh;Kwon, Dong-Soo
    • 한국HCI학회:학술대회논문집
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    • 2008.02a
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    • pp.332-336
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    • 2008
  • For reliable real-time interaction in a camera-tracked laser pointer system, a new idea is proposed and its feasibility is tested in this paper. In order to improve response time in the system and remove useless visual overload, the function of a laser pointer in the system is divided, the Region of Functional Interest is defined and subsequently its new interactions are introduced. Finally the experiments to measure reliability, accuracy, latency and usability are conducted and the results are presented.

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Gene Expression Profiling in Rice Infected with Rice Blast Fungus using SAGE

  • Kim, Sang-Gon;Kim, Sun-Tae;Kim, Sung-Kun;Kang, Kyu-Young
    • The Plant Pathology Journal
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    • v.24 no.4
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    • pp.384-391
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    • 2008
  • Rice blast disease, caused by the pathogenic fungus Magnaporthe grisea, is a serious issue in rice (Oryza sativa L.) growing regions of the world. Transcript profiling in rice inoculated with the fungus has been investigated using the transcriptomics technology, serial analysis of gene expression (SAGE). Short sequence tags containing sufficient information which are ten base-pairs representing the unique transcripts were identified by SAGE technology. We identified a total of 910 tag sequences via the GenBank database, and the resulting genes were shown to be up-regulated in all functional categories under the fungal biotic stress. Compared to the compatible interaction, the stress and defense genes in the incompatible interaction appear to be more up-regulated. Particularly, thaumatin-like gene (TLP) was investigated in determining the gene and protein expression level utilizing Northern and Western blotting analyses, resulting in an increase in both the gene and the protein expression level which arose earlier in the incompatible interaction than in the compatible interaction.

Modular neural network in prediction of protein function (단위 신경망을 이용한 단백질 기능 예측)

  • Hwang Doo-Sung
    • The KIPS Transactions:PartB
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    • v.13B no.1 s.104
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    • pp.1-6
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    • 2006
  • The prediction of protein function basically make use of a protein-protein interaction map based on the concept of guilt-by-association. The method however cannot determine the functions of proteins in case that the target protein does not interact with proteins with known functions directly. This paper studies protein function prediction considering the given problem as a K-class classification problem and proposes a predictive approach utilizing a modular neural network. The proposed method uses interaction data and protein related attributes as well. The experimental results demonstrate that the proposed approach can predict the functional roles of Yeast proteins whose interaction knowledge is not known and shows better performance than the graph-based models that use protein interaction data.

Biochemical and Biophysical Characterizations of the Interaction between Two PDZ Adapter Proteins NHERF and E3KARP in vitro

  • Hwang, Eun-Young;Jeong, Mi-Suk;Jang, Se-Bok
    • Bulletin of the Korean Chemical Society
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    • v.31 no.11
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    • pp.3241-3246
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    • 2010
  • NHERF ($Na^+/H^+$ exchanger regulatory factor) and E3KARP (NHE3 kinase A regulatory protein) play important roles in membrane targeting, trafficking and sorting of ion channels, transmembrane receptors and signaling proteins in many tissues. Each of these proteins contains two PDZ (PSD-95/Dlg-1/ZO-1) domains, which mediate the assembly of transmembrane and cytosolic proteins into functional signal transduction complexes. The interaction between NHERF and E3KARP was investigated by surface plasmon resonance spectroscopy (BIAcore), fluorescence measurement, His-tagged pull-down experiment, and size-exclusion column (SEC) chromatography. BIAcore experiments revealed that NHERF bound to E3KARP with an apparent $K_D$ of 7 nM. Fluorescence emission spectra of the NHERF-E3KARP complex suggested that the tight interaction between these proteins was accompanied by significant conformational changes in one or both. The CD spectra of NHERF and E3KARP show that the conformational changes of these proteins were dependent on pH and temperature. These results implicate that the NHERF-E3KARP complex allows intracellular signaling complexes to form through PDZ-PDZ interactions.

Cooperativity of the Interaction of Nucleohistone and DNase 1, and Effects of Spermine and Dansylation on It (Nucleohistone과 DNase 1 과의 相互作用의 Cooperativity 및 이에 미치는 Spermine과 Dansylation 效果)

  • Chan Yong Lee;Ko Thong Sung
    • Journal of the Korean Chemical Society
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    • v.29 no.3
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    • pp.304-310
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    • 1985
  • Effect of spermine on the susceptibility of calf thymus nucleohistone to DNase 1, in relation to the structural change of the nucleohistone, and cooperativity of the interaction of the nucleohistone with DNase 1 was investigated. Dansylated nucleohistone, in which the histone moiety had been derivatized by dansylation, was also used to investigate functional roles of the histone moiety on the cooperativity. The data here indicate the possibility that the nucleohistone, in contrast with the DNA, may not undergo monomolecular condensation, whereas intermolecular aggregation and enhancement of the positive cooperativity of the interaction of nucleohistone with DNase 1 may be brought about by spermine. The interaction of the DNS-nucleohistone with DNase 1 showed negative cooperativity. Based on the data here, it can be speculated that the cooperativity of the nucleohistone is influenced by the histone moiety of the nucleohistone.

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Exploring Community Structure and Function with Network Analysis: a Case Study of Cheonggye Stream (생태계 네트워크 분석을 이용한 생물 군집의 구조와 기능에 대한 연구: 청계천을 사례로)

  • Lee, Minyoung;Kim, Yongeun;Cho, Kijong
    • Korean Journal of Environmental Biology
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    • v.36 no.3
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    • pp.370-376
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    • 2018
  • It is important to consider interaction between species in understanding structure and function of the biological community. Current ecological issues such as climate change and habitat loss emphasize the significance of the concept of species interaction in that varying species' interaction across environmental gradients may lead to altered ecological function and services. However, most community studies have focused on species diversity through analysis of quantitative indices based on species composition and abundance data without considering species interactions in the community. 'Ecological network analysis' based on network theory enables exploration of structural and functional properties of ecosystems composed of various species and their interactions. In this paper, network analysis of Cheonggye stream as a case study was presented to promote uses of network analysis on ecological studies in Korea. Cheonggye stream has a simple biological structure with link density of 1.48, connectance 0.07, generality 4.43, and vulnerability 1.94. The ecological network analysis can be used to provide ecological interpretations of domestic long-term monitoring data and can contribute to conserving and managing species diversity in ecosystems.

Seismic control of concrete buildings with nonlinear behavior, considering soil structure interaction using AMD and TMD

  • Mortezaie, Hamid;Zamanian, Reza
    • Structural Engineering and Mechanics
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    • v.77 no.6
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    • pp.721-734
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    • 2021
  • The seismic analysis of structures without applying the effects of soil can undermine functional objectives of structure so that it can affect all the desired purposes at the design and control stages of the structure. In this research, employing OpenSees and MATLAB software simultaneously and developing a definite three-dimensional finite element model of a high-rise concrete structure, designed using performance-based plastic design approach, the performance of Tuned Mass Damper (TMD) and Active Mass Damper (AMD) is both examined and compared. Moreover some less noted aspects such as nonlinear interaction of soil and structure, uplift, nonlinear behavior of structure and structural torsion have received more attention. For this purpose, the analysis of time history on the structural model has been performed under 22 far-field accelerogram records. Examining a full range of all structural seismic responses, including lateral displacement, acceleration, inter-story drift, lost plastic energy, number of plastic hinges, story shear force and uplift. The results indicate that TMD performs better than AMD except for lateral displacement and inter-story drift to control other structural responses. Because on the one hand, nonlinear structural parameters and soil-structure interaction have been added and on the other hand, the restriction on the control force applied that leads up to saturation phenomenon in the active control system affect the performance of AMD. Moreover, the control force applied by structural control system has created undesirable acceleration and shear force in the structure.