• Nutrition Research and Practice
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• 제6권6호
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• pp.491-498
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• 2012

Glycyrrhiza uralensis (or licorice) is a widely used Oriental herbal medicine from which the phenylflavonoids dehydroglyasperin C (DGC), dehydroglyasperin D (DGD), and isoangustone A (IsoA) are derived. The purpose of the present study was to evaluate the antioxidant properties of DGC, DGD, and IsoA. The three compounds showed strong ferric reducing activities and effectively scavenged DPPH, $ABTS^+$, and singlet oxygen radicals. Among the three compounds tested, DGC showed the highest free radical scavenging capacity in human hepatoma HepG2 cells as assessed by oxidant-sensitive fluorescent dyes dichlorofluorescein diacetate and dihydroethidium bromide. In addition, all three compounds effectively suppressed lipid peroxidation in rat tissues as well as $H_2O_2$-induced ROS production in hepatoma cells. This study demonstrates that among the three phenylflavonoids isolated from licorice, DGC possesses the most potent antioxidant activity, suggesting it has protective effects against chronic diseases caused by reactive oxygen species as well as potential as an antioxidant food additive.

• 한국식품저장유통학회지
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• 제13권5호
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• pp.643-648
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• 2006

본 연구는 뜰보리수 열매의 식품영양학적 평가 및 기능성 물질 발굴의 일환으로 뜰보리수 열매를 이용하여 성숙과정 중의 free radical 소거능을 비롯한 SOD유사활성, 아질산염 소거작용, xanthine oxidase 저해활성 등의 항산화 활성을 조사하였다. 뜰보리수 에탄올 추출물의 전자공여능은 성숙함에 따라 감소하는 경향을 나타내었으며, 에탄올 추출물의 농도가 높을수록 전자공여능의 효과는 더욱 높게 나타났다. 에탄올 추출물의 SOD 유사활성은 성숙정도에 따른 증가하였고, 농도에 비례하였다. 뜰보리수 열매의 에탄을 추출물의 아질산염 소거능은 pH가 낮을수록 높았으며, 농도가 증가할수록 아질산염 소거 작용이 높게 나타났다. Xanthine oxidase 활성 저해능은 완숙과 과숙과실의 추출물에 비해서 미숙과실 추출물에서 높았다.

• 한국식품영양학회지
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• 제14권3호
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• pp.222-227
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• 2001

The production results of the oriental functional beverage, which is aimed at reducing the alcohol concentration in blood, are as follows. Different kinds of herb medicine ingredients were combined to achieve the balance between Yin And Yang. They were grouped according to their respective characteristics and extracted by heat, Then they were combined and produced following the most effective mixture ratio. The drink produced by this way consisted mainly of water, Sugar, mineral, protein and fiber were partially contained. Among the minerals, the proportion of calcium, potassium, magnesium was high and iron was also contained. This drink turned out to be effective in reducing the alcohol concentration in blood within a very short time when it was taken once after drinking and taken aging 30 minutes later, which would double the dosage. This result shows that development of such a functional beverage using the herbal medicine, At the same time it will play an important part in reducing the alcohol concentrate in blood after drinking liquors.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2006년도 한국약용작물학회 공동춘계학술발표회
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• pp.450-451
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• 2006

• 대한한의학방제학회지
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• 제21권2호
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• pp.100-109
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• 2013

Objectives : "Donguibogam(東醫寶鑑)" is a medical book of the Joseon Dynasty compiled by Heo Jun and was first published in 1613. It recorded a great deal of prescriptions which contained pork and gave detailed explanations of parts of pork's natural properties and effects. Pork is widely used as a food ingredient in the world but the traditional medicine community has a contraindication of pork and traditional herbal medicines taken together. The aim of this study was to find the supports to develop pork functional foods for the treatment of diseases in "Donguibogam". Methods : Therefore we investigated the documents recorded in "Donguibogam" about usefulness of pork which were used for not only a food ingredient but also a medicine. Results : "Donguibogam" introduced 25 parts of pork including liver, kidney, stomach, bladder, heart etc, and a variety of taking ways i.e. common usages which are internal, external, common use, and aid use which cure a variety of diseases not a simple food but a therapies food. Conclusions : We confirmed that pork has been used to treat many diseases, so we propose to develop pork functional foods available for prevention and cure of certain diseases.

• 한국식품조리과학회지
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• 제30권5호
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• pp.573-578
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• 2014

The objective of this study was to investigate the antioxidant activities and anthocyanin profiles in the anthocyanin rich fraction (ARFAM) of Aronia melanocarpa, which are considered functional substances and are available as food coloring agents in Korea. Anthocyanins were identified by reversed-phase C18 column chromatography and HPLC-DAD-ESI/MS analysis. The antioxidative activity of the acidic ethanol extract (AME) and the anthocyanin-rich fraction (ARFAM) was determined by scavenging of the diphenylpicrylhydrazyl (DPPH) radical, the hydroxy radical, and the superoxide anion in addition to reducing power using a commercial antioxidant as a reference.

• 한국식품영양과학회지
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• 제40권12호
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• pp.1675-1679
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• 2011

본 연구는 홍삼 및 전분질 원료로 산야초 발효액을 첨가하여 제조한 고추장의 이화학적 특성과 항산화 및 관능적 특성 등 품질에 미치는 영향을 조사하였다. 수분함량은 일반 시판 고추장에 비해 6% 정도 낮았고 회분과 조단백의 경우 각각 3.7%, 0.9% 정도 높게 나왔다. 조지방에 경우는 두 시료 모두 별다른 차이가 나타나지 않았다. pH는 대조군에 비해 유의적으로 낮은 편이었는데 이는 다른 기능성 소재를 첨가한 고추장보다도 낮은 값으로 홍삼과 산야초 발효액 첨가가 더 많은 유기산을 생성한 것으로 생각된다. 색도의 경우 L, b값은 홍삼, 산야초 발효액 첨가 고추장이 높은 값을 띄는 반면 a값은 시판 고추장이 더 높게 나왔다. 이러한 차이는 색도의 관한 기호도 평가에서 대조군 보다 훨씬 좋은 결과를 얻을 수 있었다. 기능적인 측면을 살펴보면, DPPH 활성의 경우 전 농도에서 대조군보다 높게 나왔지만 특히 가장 높은 농도인 100 ${\mu}g$/mL에서 유의적으로 라디칼 소거능이 우수한 것으로 나타났으며, ferric reducing antioxidant power는 모든 구간에서 유의적으로 뛰어난 항산화 활성을 보였다. 지질산화를 일으키는 효소인 lipoxygenase의 저해능을 평가한 결과 100 ${\mu}g$/mL의 고농도에서 시판 고추장뿐만 아니라 양성대조군보다 2배가량 높은 저해활성을 띄는 것으로 나타났다. 관능검사에서는 맛, 색깔, 풍미, 종합적 기호도 모든 항목에서 시판 고추장보다 유의적으로 우수하다는 평가를 얻음으로 홍삼과 산야초 발효액의 첨가가 전반적인 고추장 품질을 향상시킬 수 있었음을 알 수 있었다.

• 한국식품영양과학회지
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• 제44권9호
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• pp.1304-1310
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• 2015

본 연구에서는 저작이 용이한 노인 간식으로서 약재 추출물을 첨가한 양갱을 제조하여 품질 특성 및 항산화 활성을 평가하였고, 기능성식품으로서의 상품 가능성을 알아보고자 하였다. 약재 추출물을 첨가한 양갱(YH)과 약재 추출물을 첨가하지 않은 양갱(CY)의 수분함량은 각각 40.10%, 41.54%로 통계적 유의적 차이는 보이지 않았다. 약재 추출물을 첨가하였을 때 양갱의 pH는 감소되고 당도는 증가되는 경향을 보였다. 양갱 제조에 있어 약재 추출물 첨가가 명도와 황색도 값에 큰 영향을 미치지 않으며, 적색도 값에 영향을 주어 적색도 값을 감소시켰다. 항산화 특성을 측정한 결과 약재 추출물을 첨가한 YH의 DPPH 라디칼 소거능이 30.36%, ABTS 라디칼 소거능이 31.90%를 나타내었고 환원력이 0.35의 흡광도 값을 나타내어 가장 높은 항산화 활성을 보였으며, 폴리페놀 함량은 36.06 mg/100 g이었다(P<0.05). 양갱의 조직감을 측정한 실험 결과에서는 탄력성, 응집성, 점착성, 씹힘성 항목에서 CY와 YH는 통계적으로 유의적인 차이를 나타내지 않았으나 약재 추출물을 첨가하였을 때 점착성과 씹힘성 항목에서 모두 낮은 값을 나타내었다. 또한 관능적 특성 평가에서 YH는 경도와 씹힘성이 대체로 낮은 특성강도를 갖고 있어 저작이 어려운 노인들에게 영양 간식으로 적합하다고 판단된다.

• 대한본초학회지
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• 제22권4호
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• pp.127-135
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• 2007

Objectives : In this study we investigated the antiobese effects of mixed pills of pickled black soybeans with herbs(herbal Chokong pill, hereafter HCKP) in rats fed high-fat diet. It was evaluated by measuring the changes of body weight, adipose tissues weight and lipid profiles in serum. Methods : Black soybeans were pickled in vinegar for 15 days to prepare Chokong, at room temperature. For treatment group, HCKP was prepared, which five kinds of medicinal herbs(Rhynchosia nulubilis, Glycyrrhiza uralensis, Zizyphus vulgaris, Atractylodes macrocephala K, Astragalus membranaceus and Cornus officinalis) were added to dried Chokong. Four groups of male Sprague-Dawley rats were fed different diets during 9 weeks: normal diet containing 5%(w/w) com oil, high-fat diet containing 10%(w/w) lard plus 5%(w/w) corn oil (HF), high-fat diet supplemented with 1%(T1) and 5%(T5) HCKP powder, respectively. Results : The T5 group had markedly lower body weight gain and weights of epididymal adipose tissue when compared with HF group. There were significant differences in visceral adipose tissue weights, serum total cholesterol and triglyceride concentrations between the HF and T5 group. Then, the efficacy of powered HCKP on body weight and lipid profiles change in rats fed high-fat diet were induced dose dependantly. Conclusion : These results suggest that the possibility of HCKP, as an antiobese functional formula, by suppression of body weight gain and improved lipid profiles.

• 한국식품영양학회지
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• 제27권3호
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• pp.331-338
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• 2014

The purpose of this study was to evaluate the jujube hot-water extraction and antioxidant. After extraction of hot-water jujube, general composition analysis and functional tests were performed. The results of general composition analysis showed 22.33% of moisture content, 0.71% of crude lipid, 5.21% of crude protein, and 3.87% of ash. From DPPH test results, in concentrations of $1,000{\mu}g/mL$ of jujube extracts, electron donating ability was shown with 68.24%. The SOD ability in concentrations of $1,000{\mu}g/mL$ was 13.12%. The nitrite scavenging ability of jujube extracts was 11.79% at $1,000{\mu}g/mL$. The yogurt with 0, 1, 2, 3 and 4% of jujube extracts was made, and the general composition analysis and the functional tests were performed. The results of the general composition analysis of jujube yogurt, showed 74.71~76.56% of moisture contents, 1.31~3.38% of crude lipid, 2.13~3.40% of crude protein, and 1.18~1.28% of ash. The DPPH test results showed 46.33% for 1% added jujube extract, 53.78% for 2% added jujube extract, 90.87% for 3% added jujube extract, and 89.58% for 4% added jujube extract. The SOD ability showed 4.93% for 1% added jujube extract, 7.28% for 2% added jujube extract, 11.38% for 3% added jujube extract, and 11.50% for 4% added jujube extract.