• 대한교통학회지
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• 제25권3호
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• pp.65-74
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• 2007

1995년 이후 연평균 6.2%의 증가율을 보이는 자동차 등록대수에 반해 연평균 교통사고 발생건수는 1.5%, 사망자 4.7% 및 부상자 0.3%씩 감소추세를 보이고 있어 매우 다행스러운 일이나, OECD국가와 비교해서는 여전히 높은 교통사고율을 보이는 것이 사실이다. 이에 정부 및 각 기관에서는 교통사고를 감소시키기 위해 지속적인 교통안전사업을 추진하고 있으나, 각 제도 및 사업에 대한 시행 효과를 측정하는 부분에 대해서는 소홀히 하고 있는 현실이다. 정부가 교통안전을 위한 사업의 일환으로 시행중인 자동차검사제도는 차량의 도로운행 적합성 확인을 통해 자동차의 안전도 확보 및 교통사고로 인한 국민의 생명과 재산을 보호하는 것을 목적으로 하고 있다. 하지만. 이 제도에 대한 효과분석이 제대로 이루어지지 않은 상황이고, 자동차검사제도와 무관하게 운전자 스스로 자동차의 안전관리 상태를 수시 점검한다는 의견 등 자동차 검사방법, 검사기준, 검사의 실효성 저하에 대한 논의가 지속적으로 제기되고 있는 실정이다. 이에 본 연구에서는 자동차검사제도가 구조장치의 안전성을 향상시키고. 자동차성능을 유지시킴으로써 자동차결함으로 인해 발생 가능한 교통사고의 사전예방에 어느 정도 기여하는지 정량적으로 보임으로써 자동차검사제도의 효과를 측정 해 보고자 하였다. 2005년도 자료를 기준으로 교통사고 감소건수를 추정해 본 결과 자동차검사제도 시행을 통한 교통사고 감소건수는 약 23,735건으로, 이는 2005년 총 교통사고 건수 214,171의 11%에 달하는 것으로 나타났다.

• 한국지리정보학회지
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• 제17권4호
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• pp.144-155
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• 2014

과거 성장 중심의 산업화 과정에서 형성된 대규모 산업단지를 비롯한 공업지역이 기반시설 부족과 노후화로 인해 지방도시의 도시경쟁력을 악화시키는 요인으로 작용하고 있다. 이러한 인식하에 최근들어 정부주도의 노후산업단지 재생사업이 시범적으로 추진되고 있으나 지역마다의 산업단지의 형성여건과 물리적 환경이 상이하여 획일화된 재생계획의 우려가 있는 실정이다. 이에 본 연구에서는 과거 민간주도로 조성된 부산 사상공업지역을 사례로 지역의 사회적 여건과 물리적 현황을 바탕으로 지역특성을 진단하고 재생방향을 제시하고자 하였다. 분석결과 사례지역은 사회적 측면에서 시역확장에 따른 입지적 도시기능 변화와 김해, 양산 등 주변도시의 급격한 성장에 따른 기업유출로 공업기능의 잠식, 물리적 여건측면에서는 기반시설 미흡 및 개발압력 가중으로 요약된다. 이를 바탕으로 향후 수립할 재생정책의 방향으로서 계획수립단계에서는 공공주도의 기반시설 확충에 우선하고 시범적으로 일부지역에 대한 우선정비구역 지정을 통한 전면철거방식 적용이 필요하다. 실행단계에서는 중장기적 관점에서 단계적 사업이 필요하며 협력적 거버넌스 구축을 통한 재생사업 추진과정에서 기업과의 공감대 형성이 중요할 것으로 여겨진다.

• Journal of Ecology and Environment
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• 제29권3호
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• pp.247-252
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• 2006

울릉도의 특산 식물종으로서 희귀식물종이며, 춘계 단명성 식물로서 개미에 의해 종자 산포가 이루어지는 섬현호색(Corydalis filistipes Nakai) 4개의 아집단에 대하여 합리적인 보전 및 관리 대책 수립을 위하여 9 개의 동위효소 marker를 이용하여 유전적 다양성과 구조를 분석하였다. 그 결과 평균 대립 유전자의 수(A)는 1.73개, 95% 수준에서 다형적 유전자좌의 비율은(P)은 61.2%, 이형접합체의 평균 관측치(Ho)는 0.201, 기대치(He)는 0.167로서 분포역이 넓은 특산 식물 종들에 비해서는 낮은 수준이지만, 섬에 고립된 유사한 생활사를 갖는 특산식물 종들에 비해서는 높은 유전적 다양도를 유지하고 있는데, 그 이유는 소집단이기는 하나 적정수준의 개체수가 유지되고 있고, 타가수정을 주로 하며 개미에 의해 종자 산포가 이루어져 적응력이 높고, 또한 폐쇄화에 의한 유 무성 번식 체계를 겸하기 때문인 것으로 판단된다. 그리고 유전적 구조분석 결과 아집단내($F_{IS}$)와 전체 아집단($F_{IT}$)의 근친교 배계수가 각각 -0.1889 와 -0.1226로서 H-W의 평형구조에 비해 이형접합자의 빈도가 높았으며, 아집단간 유전적 분화도는 매우 낮은($F_{ST}=0.0557$)결과를 보였다. 그리고 우리나라 희귀 및 특산 식물종인 섬현호색의 유전적 변이의 유지 기작과 합리적인 보전과 관리 대책을 논의하였다.

• KIEAE Journal
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• 제16권6호
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• pp.39-50
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• 2016

Purpose: The purpose of this study is to be performed with studio-type housings among urban life-type housings to investigate the physical characteristic and crime-related factors of studios from the viewpoint of the basic principles of crime prevention through environmental design (CPTED). Method: Eight CPTED guidelines available in Korea were reviewed to select 20 planing factors for actual condition investigation. Five single households in studio-type housings in Gwanak-gu, Seoul, were chosen according to the subject screening criteria to perform the actual condition investigation. Results: First, a lighting plan around a building for natural surveillance should consider the building location, relation with the front road, and surrounding facilities. In a building of a piloti structure, the parking lot and the building gate should be arranged in a manner that enables natural surveillance. Second, the shape of the corridors in studio-type housings should be considered to plan the installation of a lighting at the door of each household, the installation of a viewer window at the door of each household, and the arrangement of the elevator. Third, to support access control, an access control system having the function of video and voice communication is recommended to be installed at the building gate. Criteria for the type of security windows and the floors on which security windows should be installed, and the regulations about the CCTV installation inside and outside the building should be prepared. Fourth, to enhance territoriality in parking lots, ground patterns, parking lot gate, and signs may be installed. Fifth, in view of effective utilization and maintenance, lighting facilities should be installed to increase the usability of ground parking lots, and relevant installation criteria should be prepared regarding the type, number, and brightness of the lightings.

• Tuberculosis and Respiratory Diseases
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• 제49권1호
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• pp.93-98
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• 2000

Acute respiratory distress syndrome (ARDS) has been reported to be associated with a variety of medical and surgical conditions, including All-trans-retinoic acid (ATTA). ATRA is very efficaceous drug to acute promyelocytic leukemia (APL). This drug can induce complete remission at APL without fatal risk of disseminated intravascular coagulation. But ATRA treatment, sometimes, produces the symptoms of fever, weight gain and acute respiratory distress, renal function impairment. The causes of these symptoms are not fully proved, but supposed as the result of leukostasis and capillary leak syndrome from excessive leukocyte differentiation and cytokines release. Recently, we experienced a 24-year-old woman who complained gum bleeding for 6 days. At bone marrow biopsy, she was diagnosed as APL. 2 days after ATRA treatment, she was suffered from the symptoms of dyspnea and general ache. At laboratory examination, total leukocyte count was 50,400/$mm^3$, $PaO_2$ was 42.5 mm Hg and chest PA revealed the findings compatible with ARDS. Treatment with low dose ara-C, corticosteroid and general supportive cares were tried. Within 3 days after treatment, the patient recovered from ARDS by evidence of arterial blood gas study and chest radiographs. She has acquired complete remission of APL with maintenance of A TRA. And so, we present this case with a review of related literatures.

• 여성건강간호학회지
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• 제5권1호
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• pp.133-145
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• 1999

The purposesof the study are to analyze the community nursing center in U.S.A and to develop the model of nursing care system based on nurse-midwifery clinic in community for women's health in Korea. 1. In America nursing center is defined as nurse-anchored system of primary care delivery or neighborhood health center. Nursing centers are identified the following four types: (1) community outreach centers, which are similar to traditional public health clinics: (2) institutional-based centers following the mission of a large institution, such as a hospital or university: (3) wellness/health promotion centers, which offer screening, education, counseling, triage, and health maintenance services: and (4) independent practice. Nursing centers are a concept of services provided by nurses in practice arrangements in a community. Nursing centers offer a variety of services, ranging from primary care provided by advanced practice nurses with medical acute management and nursing care to the more traditional education, health promotion, screening wellness and coordination services. Some services, such as the care provided by advanced practice nurses are reimbursed under various insurance plan in some instances and states, where as others, such as preventive and educational services, are not. Thus, lack of reimbursement has threatened the survival of some centers. Licensing of nursing centers varies by state and program and accreditation of nursing centers is also limited. 52% of centers are affiliated with another facility and 48% are freestanding centers. The number of registered nurse at the nursing centers ranges from just one to 115, with a mean of eight RNs peragency and a median of three. Nursing centers avail ability varies: 14% are open 24 hours, 27% have variable short hours, 23% are open 6-7 days per week, and 36% are open Monday- Friday. As the result of my visiting three health centers in Seattle and San Francisco, the women's primary care nurse practitioners focus on a systematic and comprehensive assessment of the health status of women and diagnosis and management of common physical and psychosocial health concerns of women in ambulatory settings. Therapeutic nursing strategies are directed toward self-care, risk reoduction, health surveillance, stress reduction, healthy nutrition, social support, healthy coping, psychological well-being, and pharmacological therapy. They function as primary care providers for the well ness and illness care of women from adolescence through the older adult years and pregnant families. 2. In Korea a nurse-midwife practices independently for pregnant women's health including childbearing family at her own clinic in community. Her services are reimbursed under national health insurance but they are not paid on a fee-for-service schedule covering items. Analyzing the nursing centers in America, I suggest that nurse-midwifery clinics offer primary care for women and home care for chronic ill patients. The health law and health insurance policy should be reovised in order to expand nurse-midwife's and home care nurse's roles at nurse-midwifery clinic.

• Asian-Australasian Journal of Animal Sciences
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• 제12권7호
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• pp.1096-1103
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• 1999

A study was conducted to clarify the impact of recombinant porcine somatotropin (pST) on the efficiency of absorbed nitrogen use for protein deposition in growing pigs. Three levels of dietary crude protein (9.0, 11.5, 14.0% CP) were used. Each had either a sub-optimum or near optimum lysine: CP concentration (Low-lysine, 3.8 g/100 g CP and High-lysine, 5.5 g/100g CP) in order to achieve different metabolic efficiencies for nitrogen deposition (ca. 45 vs. 60%). Twelve crossbred female pigs $(59{\pm}4kg\;BW)$ were placed in metabolism cages and fitted with bladder catheters. Each pig received an excipient injection daily for the first 10-d, a pST (5 mg/d) injection for the second 10-d, and then excipient for the last 10-d. Pigs were randomly assigned to one of six dietary treatments (2 pigs/diet) and fed 4 times per d at $92g/kg\;BW^{0.75}$ $(3{\times}maintenance)$. Means for the excipient period were compared to means for the pST period. Urinary nitrogen (N) output declined in pST-treated pigs (p<0.01) irrespective of dietary protein content or lysine level. Nitrogen retention increased by an average of 11% (p<0.01) with pST treatment (726 vs. $803mg\;N/kg^{0.75}\;BW/d$). Forty-eight percent of the absorbed N was retained with Low-lysine diets, but this increased to 53% with pST injection (+11%, p<0.01). Pigs fed High-lysine diets retained 62% of absorbed N which increased to 69% with pST (+11% p<0.01). the addition of lysine improved N use by 27% (High vs. Low, p<0.01), but the effect of lysine and pST was additive (+40%). Therefore, pST improves N retention and the efficiency of apparently absorbed N use in growing pigs (>60kg). It does so with diets having the potential for either low or high efficiencies of N use (48% and 62%). More work is needed to determine if the partial efficiency of N use improves in direct proportion to pST dose since the improvement in protein deposition is a function of pST dose.

• 대한치과의사협회지
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• 제55권8호
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• pp.528-536
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• 2017

Treatment with removable partial denture is effective for partially edentulous patients who are unable to obtain sufficient retention and stability for functional and esthetic restoration. There are several cases reporting the improvement of retention and stability of the partial denture using a small number of implants. However, there are limited studies on the implant-assisted removable partial denture using a small number of remaining teeth and the bar locator system. The bar locator system has an advantage in that it could compensate the angle of insertion of removable prosthesis on implant with inconsistent placement angle due to anatomical constraints compared to when using the locator only. This case report describes the patient with $Parkinson^{\circ}$Øs disease who was treated with the Locator bar system using two previously placed implants and two remaining teeth on maxilla. No additional implants could be placed because of the medical and economic condition of the patients, and the angle of one of two implants could not be matched with the direction of the removable partial denture insertion. Considering the angle of the implants, the patient was treated with implant-assisted RPD using the Locator bar system and had satisfactory results in the aspect of esthetics, masticatory function, and oral hygiene maintenance.

• Asian-Australasian Journal of Animal Sciences
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• 제30권5호
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• pp.643-652
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• 2017

Objective: Prostaglandins (PGs) function in various reproductive processes, including luteolysis, maternal pregnancy recognition, conceptus development, and parturition. Our earlier study has shown that PG transporters ATP-binding cassette, subfamily C, member 4 (ABCC4) and solute carrier organic anion transporter family, member 2A1 (SLCO2A1) are expressed in the uterine endometrium in pigs. Since several other PG transporters such as ABCC1, ABCC9, SLCO4C1, and SLCO5A1 are known to be present in the uterine endometrium, this study investigated the expression of these PG transporters in the porcine uterine endometrium and placenta. Methods: Uterine endometrial tissues were obtained from gilts on day (D) 12 and D15 of the estrous cycle and days 12, 15, 30, 60, 90, and 114 of pregnancy. Results: ABCC1, ABCC9, SLCO4C1, and SLCO5A1 mRNAs were expressed in the uterine endometrium, and levels of expression changed during the estrous cycle and pregnancy. Expression of ABCC1 and ABCC9 mRNAs was localized mainly to luminal and glandular epithelial cells in the uterine endometrium, and chorionic epithelial cells during pregnancy. Conceptuses during early pregnancy and chorioallantoic tissues from mid to late pregnancy also expressed these PG transporters. $Estradiol-17{\beta}$ increased the expression of ABCC1 and SLCO5A1, but not ABCC9 and SLCO4C1 mRNAs and increasing doses of $interleukin-1{\beta}$ induced the expression of ABCC9, SLCO4C1, and SLCO5A1 mRNAs in endometrial explant tissues. Conclusion: These data showed that several PG transporters such as ABCC1, ABCC9, SLCO4C1, and SLCO5A1 were expressed at the maternal-conceptus interface, suggesting that these PG transporters may play an important role in the establishment and maintenance of pregnancy by regulating PG transport in the uterine endometrium and placenta in pigs.

• Asian-Australasian Journal of Animal Sciences
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• 제28권6호
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• pp.771-781
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• 2015

Thoroughbred, a relatively recent horse breed, is best known for its use in horse racing. Although myostatin (MSTN) variants have been reported to be highly associated with horse racing performance, the trait is more likely to be polygenic in nature. The purpose of this study was to identify genetic variants strongly associated with racing performance by using estimated breeding value (EBV) for race time as a phenotype. We conducted a two-stage genome-wide association study to search for genetic variants associated with the EBV. In the first stage of genome-wide association study, a relatively large number of markers (~54,000 single-nucleotide polymorphisms, SNPs) were evaluated in a small number of samples (240 horses). In the second stage, a relatively small number of markers identified to have large effects (170 SNPs) were evaluated in a much larger number of samples (1,156 horses). We also validated the SNPs related to MSTN known to have large effects on racing performance and found significant associations in the stage two analysis, but not in stage one. We identified 28 significant SNPs related to 17 genes. Among these, six genes have a function related to myogenesis and five genes are involved in muscle maintenance. To our knowledge, these genes are newly reported for the genetic association with racing performance of Thoroughbreds. It complements a recent horse genome-wide association studies of racing performance that identified other SNPs and genes as the most significant variants. These results will help to expand our knowledge of the polygenic nature of racing performance in Thoroughbreds.