• Asian-Australasian Journal of Animal Sciences
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• v.22 no.3
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• pp.313-318
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• 2009

TIAF1 is a TGF-${\beta}$1-induced anti-apoptotic factor that plays a critical role in blocking TNF (tumor necrosis factor) cytotoxicity in mouse fibroblasts and participates in TGF-${\beta}$-mediated growth regulation. In this study, we obtained the full-length cDNA sequence of the porcine TIAF1 gene. Real-time PCR further revealed that the TIAF1 gene was expressed at the highest level in liver and kidney with prominent expressions detected in uterus, and lower levels detected in heart, spleen, lung, stomach, small intestine, skeletal muscle and fat of Large White pigs. Sequence analysis indicated that a 6 base-pair deletion mutation existed in the exon of the TIAF1 gene between Meishan and Large White pigs. This mutation induced deletion of Gln and Val amino acids. PCR-RFLP was used to detect the polymorphism in 394 pigs of a "Large White${\times}$Meishan" $F_{2}$ resource population and four purebred pig populations. The frequencies of the A allele (with a 6 bp deletion) were dominant in Chinese Meishan and Bamei pigs, and the frequencies of the B allele (no 6 bp deletion) were dominant in Large White and Landrace pigs. Association analyses revealed that the deletion mutation had highly significant associations (p<0.01) with meat marbling score of the thorax-waist longissimus dorsi (LD) muscle (MM1) and intramuscular fat percentage (IMF), and significant associations (p<0.05) with carcass length (CL). The results presented here supply evidence that the 6 bp deletion mutation in the TIAF1 gene affects porcine meat quality and provides useful information for further porcine breeding.

• Journal of Korean Physical Therapy Science
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• v.10 no.2
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• pp.173-183
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• 2003

The purpose of this study was to provide information for making positive interpersonal relations by understanding the degree of difficulties of interpersonal relations that physical therapist students may have on clinical practice. The survey results of 175 students who completed clinical practice for the first term of 2003. The survey was conducted through mail or e-mail between July 20 and August 20, 2003. The data were analyzed frequency, percentage, t-test, and one-way ANOVA using the SPSS/PC Ver. 10.0 (${\alpha}=0.05$). The results were as follows; 1. The mean score for the level of points interpersonal relations was 41.06 points in full 80 points. Therefore most students had a little problem on interpersonal relations. 2. More difficulties of interpersonal relations were felt by students in the following order; clinical instructors, patients, other students, and other department staffs in the hospital. 3. Between students and clinical physical therapist in the hospital, most students were satisfied with a instructor's attitude toward there (61.1%). 4. Between students and other department staffs in the hospital, most students were felt convenient when faced with other staffs(61.8%). 5. Between students and patients in the hospital, most students didn't uncomfortable when they made a rapport(69.2%). 6. Between students and other college students, most students were didn't inconvenient when they were practicing together(69.8%). 7. The students with higher marks in major felt more difficulties for forming personal relations with other department staffs in hospital, patient, and other students(p<0.05). 8. The students showed more felt inconveniences over 8 weeks practicing than below 7 weeks itperiods of clinical practice(p<0.05). 9. The number of practice place were significantly difference according to relation of patients, other college students(p<0.05). More less practice place were made difficult of interpersonal relations. The further studies would be made in viewpoints to clinical instructors, patients, students, others department staffs in the hospital so that we could compare our results with theirs.

• The Korean Journal of Pharmacology
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• v.24 no.1
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• pp.1-10
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• 1988

To obtain information about the structure of the human phenylethanolamin N-methyltransferase (PNMT) and to further define the extent of the evolutionary relationships among PNMT molecules of several spesies, a full length cDNA clone for bovine adrenal PNMT was used to screen a charon 4A genomic library. One phage was isolated and identified, which included the entire PNMT gene. The length of inserted genomic DNA was 13.1-Kilobase (Kb) containing two internal EcoRI sites. Construction of a restriction map and subsequent Southern and dot blot analysis with 5'-and3'-specific cDNA probes allowed the identification of exon-containing fragments. This is the first report of the cloning of gene for human epinephrine synthesizing enzyme.

• Journal of Distribution Science
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• v.13 no.11
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• pp.123-130
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• 2015

Purpose - Due to highly elevated levels of competition, many companies today have to face the problem of decreasing profits even when their actual sales volume is increasing. This is a common phenomenon that is seen occurring among companies that focus heavily on quantitative growth rather than qualitative growth. These two aspects of growth should be well balanced for a company to create a sustainable business model. For supply chain management (SCM) planners, the optimized, quantified flow of resources used to be of major interest for decades. However, this trend is rapidly changing so that managers can put the appropriate balance between sales volume and sales quality, which can be evaluated from the profit margin. Profit optimization is a methodology for companies to use to achieve solutions focused more on profitability than sales volume. In this study, we attempt to provide executional insight for companies considering implementation of the profit optimization system to enhance their business profitability. Research design, data, and methodology - In this study, we present a comprehensive explanation of the subject of profit optimization, including the fundamental concepts, the most common profit optimization logic algorithm -linear programming -the business functional scope of the profit optimization system, major key success factors for implementing the profit optimization system at a business organization, and weekly level detailed business processes to actively manage effective system performance in achieving the goals of the system. Additionally, for the purpose of providing more realistic and practical information, we carefully investigate a profit optimization system implementation case study project fulfilled for company S. The project duration was about eight months, with four full-time system development consultants deployed for the period. To guarantee the project's success, the organization adopted a proven system implementation methodology, supply chain management (SCM) six-sigma. SCM six-sigma was originally developed by a group of talented consultants within Samsung SDS through focused efforts and investment in synthesizing SCM and six-sigma to improve and innovate their SCM operations across the entire Samsung Organization. Results - Profit optimization can enable a company to create sales and production plans focused on more profitable products and customers, resulting in sustainable growth. In this study, we explain the concept of profit optimization and prerequisites for successful implementation of the system. Furthermore, the efficient way of system security administration, one of the hottest topics today, is also addressed. Conclusion - This case study can benefit numerous companies that are eagerly searching for ways to break-through current profitability levels. We cannot guarantee that the decision to deploy the profit optimization system will bring success, but we can guarantee that with the help of our study, companies trying to implement profit optimization systems can minimize various possible risks across various system implementation phases. The actual system implementation case of the profit optimization project at company S introduced here can provide valuable lessons for both business organizations and research communities.

• Journal of Korea Multimedia Society
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• v.12 no.2
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• pp.209-218
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• 2009

3D backprojection is a kind of reconstruction algorithm to generate volume data consisting of tomographic images, which provides spatial information of the original 3D data from hundreds of 2D projections. The computational time of backprojection increases in proportion to the size of volume data and the number of projection images since the value of every voxel in volume data is calculated by considering corresponding pixels from hundreds of projections. For the reduction of computational time, fast GPU based 3D backprojection methods have been studied recently and the performance of them has been improved significantly. This paper presents two multiple GPU based methods to maximize the parallelism of GPU and compares the efficiencies of two methods by considering both the number of projections and the size of volume data. The first method is to generate partial volume data independently for all projections after allocating a half size of volume data on each GPU. The second method is to acquire the entire volume data by merging the incomplete volume data of each GPU on CPU. The in-complete volume data is generated using the half size of projections after allocating the full size of volume data on each GPU. In experimental results, the first method performed better than the second method when the entire volume data can be allocated on GPU. Otherwise, the second method was efficient than the first one.

• Journal of Nutrition and Health
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• v.23 no.2
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• pp.124-134
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• 1990

To investigate nutritional and growth status of premature infants, survey was conducted against 19 premature infants admitted to Nursery of Pediatrics, Young nam University Hospital from Jan. 1984 to July 1988. Variations in feeding patterns as analyzed through the five feeding phases of dextrose, dextrose/hyperal, dextrose/formula, dextrose/hyperal/formula and formula. During 30days from birth, dietary intake, feeding phase, selective anthropometric measurements, biochemical parameters and demograpic information of premature infants were as follows: Distributions of birth weight by gestational age and apgar score showed preamture infants below 1499g were 31 weeks, 4/7(1min/5min) and premature infants from 1500g to 1999g were 33 weeks, 8/9(1min/5min) and premature infants from 2000g to 2500g were 33 weeks, 8/9(1min/5min). Average calorie intakes of premature infants below 1499g, premature infants from 1500g to 1999g and premature infants from 2000g to 2500g were 102.0㎉/kg/day, 119.3㎉/kg/day and 101.7㎉/kg/day. The mean values Na, K, Ca, P for all premature infants remained within the normal level for full term infants throughtout the 25days of this study period. Percentages of inital weight loss showned premature infants below 1499g were 5.4%, premature infants from 1500g to 1999g were 6.4%, premature infants from 2000g to 2500g were 11.4%. Percentages of inital weight loss of the amino acid injection group and the amino acid control group were 9.4% and 9.0%.

• Cartoon and Animation Studies
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• s.31
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• pp.91-116
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• 2013

The accessibility and effect of cartoon on children are very significant. Since cartoon is a medium of conveying information through text and pictures, it has a characteristic of being easily approached by children than any other medium. Its accessibility to children is inevitably more exceptional than any other medium in the sense that it is a method of not only telling or reading stories but also showing stories. The main audience of is children. It has a characteristic of being easily accepted by children since it's mythology seen in cartoon than read in text. However, gods conducts are full of unethical expressions. Sexual expressions of intermarriages between mother and son, between brother and sister and between uncle and niece, as well as extramarital intercourse are very unethical that could have negative effects on children. This study analyzed the unethical expressions of gods that could have negative effects on children at current point in time. Zeus was often unfaithful to his wife with many stories about the children of Zeus that were created from extramarital intercourse. Standard of value on rational decision has been established for adult readers, but children can readily accept things since they lack their own rational decision on what's right and wrong. As an alternative to children's uncritical observatory study, there is a need for author's intervention to help children form desirable values. The purpose of this study is to analyze the sexual expressions of Zeus and gods in that could affect children's social study.

• Journal of Korean Society of Environmental Engineers
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• v.34 no.12
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• pp.855-862
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• 2012

Caenorhabditis elegans, a free-living nematode mainly found in the soil pore water, roles the critical function in trophic levels, energy flow, and decomposition in soil ecosystem. C. elegans is commonly used species to test soil toxicity. Recently, they are employed broadly as a test organism in nanotoxicology. In this study, a review of the toxicity of nanomaterials for C. elegans was presented based on SCI (E) papers. The nanotoxicity studies using C. elegans have been reported in 20 instances including the mechanism of toxicity. Most studies used K-medium, S-medium, and NGM (Nematode Growth Medium) plate as an exposure medium to test toxicity of nanoparticles. The effects observed include anti aging, phototoxicity, genotoxicity, and dermal effects on C. elegans exposed to nanoparticles. We found that the toxic mechanisms were related with various aspects such as lifespan abnormality, oxidative stress, distribution of particles on inter-organisms, and stress-related gene analysis. C. elegans has advantage to test toxicity of nanoparticles due to various cellular activities, full genome information, and easy observation of transparent body. C. elegans was considered to be a good test species to evaluate the nanotoxicity.

• Journal of Korean Society of Environmental Engineers
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• v.32 no.7
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• pp.690-698
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• 2010

Contamination of groundwater resources by organic chemicals has become an issue of increasing environmental concern. Surfactant-enhanced aquifer remediation (SEAR) is widely recognized as one of the most promising techniques to remediate organic contaminations in-situ. Solutions of surfactant or surfactant with polymer are used to dramatically expedite the process, which in turn, may reduce the treatment time of a site compared to use of water alone. In the design of surfactant-based technologies for remediation of organic contaminated aquifers, it is very important to have a considerable analysis using extensive numerical simulations prior to full-scale implementation. This study investigated the formation and flow of microemulsions during SEAR of organic-contaminated aquifer using the finite difference model UTCHEM, a three-dimensional, multicomponent, multiphase, compositional model. The remediation process variables considered in this study were the sequence of injection fluids, the injection and extraction rate, the concentrations of polymer in surfactant slug and chase water, and the duration of surfactant injection. For each variable, temporal changes in injection and production wells and spatial distributions of relative saturations in the organic phase were compared. Cleanup time and cumulative organic recovery were also quantified. The study would provide useful information to design strategies for the remediation of nonaqueous phase liquid-contaminated aquifers.

• The Journal of the Korea Contents Association
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• v.18 no.3
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• pp.70-80
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• 2018

Due to the recent development of social media and mobile devices, graph data have been using in various fields. In addition, caching techniques for reducing I/O costs in the process of large capacity graph data have been studied. In this paper, we propose a multi-layer caching scheme considering the connectivity of the graph, which is the characteristics of the graph topology, and the history of the past subgraph usage. The proposed scheme divides a cache into Used Data Cache and Prefetched Cache. The Used Data Cache maintains data by weights according to the frequently used sub-graph patterns. The Prefetched Cache maintains the neighbor data of the recently used data that are not used. In order to extract the graph patterns, their past history information is used. Since the frequently used sub-graphs have high probabilities to be reused, they are cached. It uses a strategy to replace new data with less likely data to be used if the memory is full. Through the performance evaluation, we prove that the proposed caching scheme is superior to the existing cache management scheme.