• The Korean Journal of Physiology and Pharmacology
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• v.15 no.6
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• pp.415-422
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• 2011

Previously, we reported that besides retinal ganglion cell (RGC) spike, there is ~10 Hz oscillatory rhythmic activity in local field potential (LFP) in retinal degeneration model, rd1 mice. The more recently identified rd10 mice have a later onset and slower rate of photoreceptor degeneration than the rd1 mice, providing more therapeutic potential. In this study, before adapting rd10 mice as a new animal model for our electrical stimulation study, we investigated electrical characteristics of rd10 mice. From the raw waveform of recording using $8{\times}8$ microelectrode array (MEA) from in vitro-whole mount retina, RGC spikes and LFP were isolated by using different filter setting. Fourier transform was performed for detection of frequency of bursting RGC spikes and oscillatory field potential (OFP). In rd1 mice, ~10 Hz rhythmic burst of spontaneous RGC spikes is always phase-locked with the OFP and this phase-locking property is preserved regardless of postnatal ages. However, in rd10 mice, there is a strong phase-locking tendency between the spectral peak of bursting RGC spikes (~5 Hz) and the first peak of OFP (~5 Hz) across different age groups. But this phase-locking property is not robust as in rd1 retina, but maintains for a few seconds. Since rd1 and rd10 retina show phase-locking property at different frequency (~10 Hz vs. ~5 Hz), we expect different response patterns to electrical stimulus between rd1 and rd10 retina. Therefore, to extract optimal stimulation parameters in rd10 retina, first we might define selection criteria for responding rd10 ganglion cells to electrical stimulus.

• Journal of Navigation and Port Research
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• v.34 no.4
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• pp.271-279
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• 2010

The Mobile Harbor(MH) is a new transportation platform that can load and unload containers to and from very large container ships in the sea. This loading and unloading by crane can be performed with only very small movements of the MH in waves because MH is operated outside of the harbor. For this reason, an anti-rolling tank(ART) and an active mass driving system(AMD) were designed to reduce MH's roll motion, especially at the natural frequency of MH. In the conceptual design stage, it is difficult to confirm the design result of theses anti-rolling devices without modeling and simulation tools. Therefore, the coupled MH and anti-rolling devices' dynamic equations in waves were derived and a simulation program that can analyze the roll reduction performance in various conditions, such as sea state, wave direction, and so on, was developed. The coupled equations are constructed as an eight degrees of freedom (DOF) motion that consists of MH's six DOF dynamics and the ART's and AMD's control variables. In order to conveniently include the ART's and AMD's control dynamics in the time domain, MH's radiated wave force was described by an impulse response function derived by the damping coefficient obtained in the frequency domain, and wave exciting forces such as Froude-Krylov force and diffraction force and nonlinear buoyancy were calculated at every simulation time interval. Finally, the roll reduction performances of the designed anti-rolling devices were successfully assessed in the various loading and wave conditions by using a developed simulation program.

• Journal of Navigation and Port Research
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• v.41 no.3
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• pp.165-172
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• 2017

Current scenarios for marine spill accidents were developed based on probable maximum spill accidents. However,, accidents of similar scale to maximum spill accidents are virtually non-existent, and training or deployment of response equipment based on these scenarios can be cost prohibitive. Current scenarios require realism for practical use and need to be designed for purpose of use. In this study we developed scenarios that may replace current scenarios by using the HNS accident standard codes based on past accident cases. Scenarios were developed by modularizing the HNS accident standard code, that is classified into three scenarios: Maximum Frequency Scenario, Maximum Damage Scenario, and Maximum Vulnerability Scenario. The situation of an accident presented in each scenario developed in this process is much like a real accident, and therefore, it is has practical application.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.11C
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• pp.1083-1090
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• 2005

This paper presents the design of a video encoder for the device of need TV-OUT function. The designed video encoder satisfies the standard conditions of International Telecommunication Union-Radiocommunication (ITU-R) BT.470. ITU-R BT.470 can be classified as NTSC, PAL or SECAM. NTSC and PAL use Amplitude Modulation (AM) to transmit color difference signals and SECAM uses Frequency Modulation (FM). SECAM must have an antic-cloche filter but the filter recommended by ITU-R BT.470 is not easy to design due to sharpness of the frequency response. So formerly the filter was designed as analog. This paper proposes that the filter is designed as digital and the special quality of the filter is transformed easy to design. And the modulation method is modified to be identical with the result required at standard. The encoder can control power consumption by output mode to apply mobile phone, mobile devices, etc. The proposed encoder is experimentally demonstrated with ALTERA FPGA APEX20KE EP20K1000EBC652-3 device and SAMSUNG LCD-TV.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37 no.4A
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• pp.205-213
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• 2012

In this paper, we propose a new channel hopping scheme based on IEEE 802.11h as a good countermeasure against jamming attacks in IEEE 802.11 wireless networks. 802.11h Dynamic Frequency Selection (DFS) is a mechanism which enables hopping to a best channel with full channel measurement, not a randomly chosen channel, when the current link quality degradation occurs due to interferers such as military radars. However, under jammer attacks, this needs a time for full channel measurement before a new channel hopping and due to link disconnection during the time network performance degradation is inevitable. In contrast, our proposed schemes make an immediate response right after a jammer detection since every device is aware of next hopping channel in advance. To do this, a next hopping channel is announced by Beacon frames and the channel is selected by full channel measurement within Beacon intervals. Simulation results show that proposed scheme minimizes throughput degradation and keeps the advantages of DFS.

• Journal of Communications and Networks
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• v.10 no.3
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• pp.239-252
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• 2008

For orthogonal frequency division multiplexing (OFDM), cyclic prefix (CP) should be longer than the length of channel impulse response, resulting in a loss of bandwidth efficiency. In this paper, we describe a new technique to restore the cyclicity of the received signal when the CP is not sufficient for OFDM systems. The proposed technique efficiently restores the cyclicity of the current received symbol by adding the weighted next received symbol to the current received symbol. Iterative CP reconstruction (CPR) procedure, based on the residual intersymbol interference cancellation (RISIC) algorithm, is analyzed and compared to the RISIC. In addition, we apply the CPR method to Alamouti space-time block coded (STBC) OFDM system. It is shown that in the STBC OFDM, tail cancellation as well as cyclic reconstruction of the CPR procedure should be repeated. The computational complexities of the RISIC, the proposed CPR, the RISIC with STBC, and the proposed CPR with STBC are analyzed and their performances are evaluated in multipath fading environments. We also propose an iterative channel estimation (CE) method for OFDM with insufficient CP. Further, we discuss the CE method for the STBC OFDM system with the CPR. It is shown that the CPR technique with the proposed CE method minimizes the loss of bandwidth efficiency due to the use of CP, without sacrificing the diversity gain of the STBC OFDM system.

• KIEE International Transactions on Power Engineering
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• v.3A no.1
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• pp.27-34
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• 2003

In this paper, the power conditioner composed of the stand-alone single-phase squirrel cage rotor type self-excited induction generator (SEIG) driven by prime movers such as a wind turbine and a micro gas turbine (MGT) is presented by using the steady-state circuit analysis based on the two nodal admittance approaches using the per-unit frequency in addition to a new state variable defined by the per-unit slip frequency along with its performance evaluations for the stand-alone energy utilizations. The stande-alone single-phase SEIG operating performances in unregulated voltage control loop are then evaluated on line under the conditions of the speed change transients of the prime mover and the stand-alone electrical passive load power variations with the simple theoretical analysis and the efficient computation processing procedures described in the part I of this paper. In addition, a feasuible PI controlled feedback closed-loop voltage regulation scheme of the stande-alone single-phase SEIG is designed on the basis of the static VAR compensate. (SVC) and discussed in experiment for the promising stand-alone power conditioner. The experimental operating performance results are illustrated and give good agreements with the simulation ones. The simulation and experimental results of the stand-alone single-phase SEIG with the simple SVC controller for its stabilized voltage regulation prove the practical effectiveness of the additional SVC control loop scheme including the PI controller with fast response characteristics and steady-sate performance improvements.

• The Korean Journal of Zoology
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• v.18 no.1
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• pp.1-8
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• 1975

The experiment has been analyzed for genetic architecture of behavioral trait in strains selected for positive and negative phototaxis in Drosophila melanogaster. Response to selection for two different directions was rapidly diverged in their phototactic scores. Realized heritabilities for the first teh generations of selection in the positive and negative strains calculated to be 3.08% and 2.86%, respectively in both sexes. The frequency of deleterious chromosomes(lethal and semilethal chromosomes) in the positively selected strain(43%) was higher than that of negatively selected one (18%). The unselected strain(27%) was intermediate frequency between both selected strains. The correlated relationship between deleterious genes and photopositive polygenes was confirmed by the phototactic behavior of the lethal heterozygotes($1_i/1_j$). Form the results, the deleterious genes induced by long term selection for phototaxis would be considered some linkage relationship with photopositive polygenes.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.17 no.6
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• pp.89-95
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• 2017

UFMC is known as a candidate for the 5G wireless communication system because it is robust against ICI and better performs in asynchronous situation than OFDM. In the UFMC system, the filtering is performed for each subband so the performance of the filter is very important. The Dolph-Chebyshev filter has been used in conventional UFMC system because of its small out-of-band radiation. However it has distortion in the sub-band and skirt characteristics is not good enough. Therefore, it is necessary to study a new type of UFMC filter which reduces the distortion in the subband and has sharp skirt characteristics. In this paper we analyze the effect of filter frequency response in UFMC system and suggest the wavelet based type of filter that substitutes the Dolph-ChebyShev filter used in the conventional UFMC system. The simulation results show that wavelet filter has better BER performance in multipath fading channels than conventional filters.

• IMMUNE NETWORK
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• v.5 no.3
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• pp.172-178
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• 2005

Background: Carcinoembryonic antigen (CEA) is well-known soluble tumor marker frequently detectable in peripheral blood of carcinoma patients and considered as good target for antigen-specific immunotherapy. However, it is known that the induction of immune response to CEA is very difficult because CEA is a self-antigen expressed in fetal cells and weakly expressed in normal colorectal epithelial cells. To enhance anti-tumor immunity specific for CEA, recombinant CEA protein was modified using listeriolysin O (LLO) for endosomal lysis and trans activator of transcription (Tat) domain for transducing extracellular proteins into cytoplasm. Methods: After immunization using dendritic cells pulsed with Tat-CEA, both Tat-CEA and LLO, and both Tat-CEA and Tat-LLO, antibody titer to CEA and LLO, cytotoxic T lymphocyte activity and the frequency of IFN-${\gamma}$ producing T lymphocytes were measured. Results: Immunization using DC pulsed with both Tat-CEA and Tat-LLO protein showed the increasement of production of CEA-specific antibody in serum, cytotoxic T lymphocyte activity, the frequency of IFN-${\gamma}$ secreting T cells, compared with DC pulsed with both Tat-CEA and LLO. Furthermore the ratio of CD8+T cell to $CD4^+$ cell among CEA-specific T cells was increased in group pulsed with both Tat-CEA and Tat-LLO. Conclusion: These results suggested that DC vaccine using Tat-LLO could be used for the development of effective immunotherapy for the treatment of tumor.