Occlusive coronary artery disease presents a potential threat to a significant population in the United States. According to many case reports, the increasing incidence of coronary artery disease due to atherosclerosis is noted in Korean, recently. Operative vascular procedures have increased steadily in number over the past 20 years in the United States. There have been many isolated case reports about coronary artery surgery, but these had little clinical impact. Nowadays, major three coronary bypass surgery has developed principally at three cardiac centers in the United States since 1967. Among three coronary bypass operation, the aorta-coronary artery saphenous vein bypass graft was first demonstrated by Favolaro and Effler at the Cleveland Clinic in 1967. We experienced one case of coronary artery disease, which was treated successfully by aorta-coronary saphenous vein graft with mild hypothermia under extracorporeal circulation in May, 1977. Saphenous vein was removed from above the knee and was 2.5 mm in diameter. The left ventricle was not vented for the left ventricle was not overdistended. Temporary artificial pace-maker-Medtronic-was implanted for the prevention and treatment of post-operative arrhythmia and heart block in post-operative first day. He is a 57 year old male businessman who had been suffered from hypertension [200 mmHg in systolic pressure] since 4 years ago, who had intermittent conservative treatment at local clinic. He had been afflicted with severe chest pain with choking sensation for 50 days. This symptom was aggravated exposing cold weather, or cold water, but was respond to rest. Pre-operative ECG revealed no any other ischemic sign except sinus bradycardia. Significant S-T segment depression was noted at lead II, AVF after double 5 minutes exercise, indicating positive Master`s test. Serum cholesterol was slight elevated to 253 mg/dl. Final pre-operative diagnosis was made by coronary arteriogram, which showed about 1.0-cm segmental 90 % occlusive atherosclerotic lesion in the proximal part of right coronary artery above the origin of acute marginal artery. Left coronary artery revealed good patency and there was no collateral circulation between right and left coronary artery .Hospital course was not eventful. He was discharged with good result on the post-operative day. He has been free from chest pain for longer than 2 years. And also the arterial flow in the coronary bypass graft is auscultated with the pocket-sized ultrasonic velocity detector, which shows the patency of the coronary bypass graft good.
Park Yoon-Kyu;Yoo Bong-Ok;Seel David J.;Lee Young-Sik;Chun Kyung-Doo
Korean Journal of Head & Neck Oncology
/
v.3
no.1
/
pp.15-24
/
1987
This study is limited to epidermoid carcinoma arising in the larynx. The 623 patients in this series comprised 1.6% of all malignant neoplasms seen during the 20-year period .from 1965 to 1984 ; it comprised 13.2% of all cancers of the head and neck registered during this period. The male: female ratio was 11:1, and the highest incidence was in the fifth decade of life. Analysis by anatomical site revealed that 51.7% were supraglottic, 36.1% glottic, and 6.8% subglottic in oriain. One-hundred eighty-nine(79%) were clinically Stage III or Stage IV lesions at the time of the first visit. Of the total of 263 cases, 113 refused treatment, 4 definite radiation for $T_1$. lesion,21 underwent palliative therapy only, and 125 underwent surgical management with intent to cure. This surgical category included 53 patients who had surgical treatment only and 72 who underwent combined therapy(preoperative radiation, postoperative radiation, or inductive chemotherapy followed by surgery and postoperative radiation). The surgical management varied from partial laryngectomy to widefield laryngectomy and ipsilateral neck dissection. In 14.4% pathologically positive node or nodes were found in the clinically negative contralateral neck nedes. Such contralateral spread was most common in supraglottic site of origin(222%). Combined modality of management was compared to single therapy. Although results at three years showed no difference in determinate disease-free survival between patients treated by surgery only and those treated by surgery followed by postoperative radiation therapy at 5 years a statistically significant difference emerged, only 36% of those receiving surgery alone surviving as compared to 65.4% in the surgery with radiation group.
Methylobacillus sp. strain SK1, which grows only on methanol, was found to grow in the absence of added copper. The doubling time (t$_{d}$ = 1.3 h) of the bacterium growing at the exponential growth phase at 30.deg.C in the absence of copper was the same as that of the cell growing in the presence of copper. The bacterium growing after the exponential phase in the absence of copper, however, grew faster than the cell growing in the presence of copper. Cells harvested after thee arly stationary phase in the presence of copper were found to exhibit no methanol dehydrogenase (MDH) activity, but the amount and subunit structure of the enzyme in the cells were almost the same as that in cells harboring active MDH. Pellets of the cells harvested after the early stationary phase in the presence of copper were pale green. Cell-free extracts prepared from cells harvested at the early stationary phase in the presence of copper were pink and exhibited MDH activity, but it turned dark-green rapidly from the surface under air. The green-colored portions of the extracts showed no MDH activity and contained c-type cytochromes that were oxidized completely. The inactive MDH activity and contained c-type cytochromes that were oxidized completely. The inactive MDH proteins in the green portions were found to have antigenic sites identical to those of the active one as the inactive MDHs in cells grown in the presence of copper. The bacterium was found to accumulate copper actively during the exponential growth phase. MDH prepared from cells grown in the presence or absence of copper was found to be more stable under nitrogen gas than under air. Methanol at 10 mM was found to enhance the stability of the MDH under air.r.
The vibrational characteristics of a radial-ply (155SR13 4PR) and a biased-ply tire (6.15-134PR) were investigated for examining the effects of tires with different structure on the ride characteristics of the vehicle. The natural frequencies at the tread band, mode shapes, and damping factors of two tires at the state of plane vibration were determined experimentally. The test work was performed at four levels of the inflation pressure, ranging from 171.7 kPa to 245.2 kPa, and three levels of the vertical load, deviating by 10% from the standard load designated by the Department of Transportation of the United States of America. The following results were drawn by the analysis of the test results: 1. The first-order natural frequencies of the radial-ply and the biased-ply tires at the tread band were 112 Hz and 159 Hz, respectively, at the state o f the free vibration when the inflation pressure of 196.2 kPa was applied. It was known that the biased-ply tire has higher resonant frequency than the radial-ply tire and the natural frequencies of the both tires move to the high frequency range as t he inflation pressure is increased. 2. The vibration modes of both tires were quite different. No big difference in mode shapes was examined as the inflation pressure was increased. But the natural frequencies of two tires were changed. For the radial-ply tire, no difference in mode shape was found whether the vertical load was applied or not. But a significant difference in mode shape was examined for the biased-ply tire. 3. Any difference was not found in damping factor as the different inflation pressures were applied. 4. When no vertical load was applied, damping factors of the radial-ply and biased-ply tire at the state of the natural vibration ranged from 2.6 to 5.9%, and from 4.1 to 7.8%, respectively. It was estimated that the radial-ply tire would have better cushioning than the biased-ply tire since the vertical spring rate of the radial-ply tire was much less than that of the biased-ply tire, even though the damping effect of the radial-ply tire was smaller than that of the biased-ply tire.
Journal of the Korean Society of Fisheries and Ocean Technology
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v.19
no.2
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pp.106-110
/
1983
As the first step to investigate the effect of ship's motion when detecting target with an echo sounder, variations in the incident sound level at the optional position within the sound beam due to roll motion of the transmitter have been measured and calculated. In this experiment, the transmitter (75 KHz) was mounted to the bottom of a FRP model of the 2,275 G. T. stern trawler and the receiver (75 KHz) was installed at each measuring point within the transmitter's beam. Then, the incident sound level was measured for the roll angles from the free roll test on the model ship. For a range of roll angle of $\pm$20$^{\circ}$from the vertical, the measuring values of the incident sound level at each measuring point were rapidly fluctuated from 12.9% to 78.1 depending on the roll angle, and agreed well with the caculated ones. Consquently, we concluded that the effect of ship's motion when detecting target with an echo sounder should be sufficiently considered.
Kim, Jin-Hwa;Na, Young;Sim, Gwan-Sub;Lee, Bum-Chun;Pyo, Hyeong-Bae
Journal of the Society of Cosmetic Scientists of Korea
/
v.32
no.4
s.59
/
pp.263-267
/
2006
Antioxidative and anti-inflammatory activities of Petasites japonicus extract were evaluated. P. japonicus extract showed 70.1% inhibition on peroxidation of linoleic acid. In the experiment using the cell permeable dye, 2',7'- dichlorofluorescein diacetate (DCFDA) as an indicator of reactive oxygen species (ROS) generation, intracellular oxidative stress in UVB-irradiated keratinocytes was shown to be decreased by P. japonicus extract. Also, UVB-induced production of interleukin-$1{\alpha}$ and prostaglandin $E_2$ in human HaCaT keratinocytes was reduced in a dose-dependent manner by treatment with P. japonicus extract. All these results suggest that P. japonicus extract can be effectively used for prevention of UV-induced adverse skin reactions such as radical production and inflammation.
Journal of Fisheries and Marine Sciences Education
/
v.10
no.2
/
pp.184-210
/
1998
The set-net fishing is involved in the trap fishing method that intercepts the fishes migrating along the coast and induces them to be in the bag net stretched in advance. And this fishing also corresponds to the licensed fishing in fisheries law. Though its annual total production of around 50,000 to 70,000 M/T is less than in other fishery section, its price becomes higher because the fishes are sold in the live fish condition. Until recently, the set-net fishing is one of the preferred fisheries on account of its less operation expense and stably operating condition in a long term. In the meantime, the industrialization in Korea having been prospered along coastal area and the over fishing in terms of the powered and larger size fishing boat make the fishing ground environment worse yearly. In addition, its difficulty becomes more worse with issuing fishery product free import in July 1997; accordingly, the strategy for the set-net fishing through business rationalization should be considered. From the discussion of the sort of set-net, general present situation and operating actual state of set-net fishing, the improved methods for business rationalization in the present paper is proposed as follows: 1. to increase the fisheries resource through prevention of the marine contamination and purification of coastal area environment. 2. to save the labour cost through the improved the fishing gear. 3. to improve the fish quality through development of the process technology. 4. to increase the income of fishers through improvement of the distribution channels.
The purpose of this study was to identify the effect of the subtalar sling ankle taping, by measuring changes in peak plantar pressure and subtalar angle during jump landing and walking in healthy subjects with subtalar sling ankle taping applied of the ankle joint. Fifty healthy subjects(8 males and 7 female, aged 22 to 25) were randomly divided into a participated in this study. They were free of musculoskeletal injury and neurologic deficit in lower extremity. The subjects were asked to perform 5M walking and single leg jump landing by under the guidance of physical therapists. Subtalar motions were typically measured as the angle made between the posterior aspect of the calcaneous and the posterior aspect of the lower leg during walking with taping or not. This measurement were made using a video system (30Hz sampling rate, rectified 60 Hz sampling rate). At the same time, peak lateral and vertical pressure were investigated using pressure distribution platforms(MatScan system) under foot during walking and single leg jump landing with taping or not. Statistical analysis was done by paired t-test and intraclass correlation coefficient [ICC(3.1)], using software SPSS. We have recently demonstrated significantly altered patterns of subtalr joint and peak plantar pressure when applied subtalar sling ankle taping(p<.05). Inversion angle of subtalar joint significantly decreased with taping(p<.05). The result suggest that pressure patterns observed in subjects are likely to result due to significant decrease in stress on ankle joint structures during jump landing and walking. Also, the result that the subtalar sling ankle taping procedure provides greater restiction of motion associated with ankle inversion. However, this study involved asymptomatic subjects without history of ankle inversion injury, further research is needed to assess the motion restraining effect of the subtalar sling ankle taping in subjects with lateral ankle instability.
Kim, Woo Jin;Bang, Young Rong;Kang, Je-Wook;Yoo, Jae Ho;Kim, Seong Hwan;Park, Jae Hong
Journal of the Korean Academy of Child and Adolescent Psychiatry
/
v.31
no.3
/
pp.154-160
/
2020
Objectives: It remains unclear whether methylphenidate (MPH) has yadverse effects on growth in children. This study aimed to investigate the association of MPH with serum biological markers of growth in children with attention-deficit/hyperactivity disorder (ADHD). Methods: The present study included 103 children with ADHD (64 drug-naive children, 39 MPH-treated children) and 112 control subjects. Children with ADHD were diagnosed on the basis of a semi-structured interview. Levels of biochemical markers of growth, including insulin-like growth factor-I, thyroid stimulating hormone (TSH), free T4, calcium, phosphorus, alkaline phosphatase, vitamin D, hemoglobin, total protein, albumin, total cholesterol, and hematocrit were measured in these individuals. Results: Except in case of TSH, no intergroup differences were found in the levels of the growth markers. The levels of TSH were found to be lower in the MPH-treated boys with ADHD than in the drug-naive and control groups (p<0.05), although the levels of TSH in all the groups were within normal limits. Conclusion: In this cross-sectional study, no significant association was found between MPH and growth markers. This calls for the need to carry out prospective longitudinal research studies in the future that investigate the effect of MPH on the growth trajectory in children.
Significant structure theory was applied to some liquid mixture systems ranging from simple monatomic molecule systems to polyatomic molecule systems, and the activity coefficients ${\gamma}$ of the liquid mixture systems were calculated over whole mole fractions using the following thermodynamic relation $RTln_{{\gamma}i} = (\frac{{\partial A}^E}{{\partial N}_i})_{T,V,N_i} $ where $A^E$ represents the excess Helmholtz free energy, and $N_i$ is the number of molecules of component i. The activity coefficients of the solutions such as monatomic molecule systems (Ar-Kr, Kr-Xe) and diatomic molecule systems $(Ar-O_2,\;N_2-CO)$ and $CH_4-Kr$ systems whose components have similar shapes for intermolecular potential curves were calculated successfully only with the ${\delta}E_s$, correction parameter for energy $E_s$, for mixture systems. For other systems such as $Ar-N_2,\;O_2-N_2\;and\;CH_4-C_3H_8$ whose components have dissimilar intermolecular potential curve shapes an additional correction parameters ${\delta}$V and even one more parameter ${\delta}$n were necessary [see Eqs.(10)∼(12)].
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