• 한국전산구조공학회논문집
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• 제17권3호
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• pp.295-308
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• 2004

본 연구에서는 기 개발된 유한요소-경계요소 조합을 통한 지반구조물 상호작용해석기법을 이용하여 주파수 특성이 다른 여러 가지 지진파를 이용한 수치해석을 통하여 지진파에 따른 거동특성을 분석하였다. 사용한 기본해의 검증을 위하여 적용된 다층 반무한 해를 Estorff 등의 연구결과와 비교하였으며, 기본해를 이용하여 개발된 지반-구조물 상호작용해석기법의 검증을 위하여 자유장해석을 수행하였다. 자유장 해석결과는 1차원 파전달 이론에 의하여 개발된 자유장응답해석 프로그램인 SHAKE의 결과와 비교하여 그 타당성을 검증하였다. 검증된 해석기법을 이용하여 특성이 다른 3종류의 지진파가 적용된 2차원 평면상의 지반-구조물 상호작용해석을 수행함으로써 지진파와 말뚝유무에 따른 지반-구조물 상호작용거동특성을 분석하였다. 해석결과 지진이 작용할 때는 말뚝기초를 사용하는 것이 반드시 유리한 결과를 주지는 않는다는 것을 알았으며, 지반의 비선형성을 고려 할때는 말뚝의 유무가 지진응답결과에 큰 영향을 미치지 않는다는 것을 알 수 있었다.

• 대한화장품학회지
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• 제32권1호
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• pp.23-28
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• 2006

본 연구는 택사의 화장품 원료로서의 특성을 알아보기 위하여 화장품의 기능들인 항산화, 미백, 세포 손상 회복 및 항염증과 관련된 다양한 실험을 실시하였다. 30, 70, 100% MeOH 용매로 추출한 택사 추출물들은 DPPH법으로 실시한 free radical scavenging assay에서 좋은 활성을 보여주었고, tyrosinase 활성 억제 시험에서도 0.5% 이상의 농도에서 농도 의존적인 활성을 보여주었다. Human fibroblast를 사용한 proliferation assay (MTT assay)에서 각 용매 추출물들은 별다른 효과를 보여주지 못했고 0.05% 이하의 농도에서는 세포 독성으로부터 안전하다는 것을 알 수 있었다. Bl6 melanocyte를 사용한 melanin 생성 억제시험에서 각 용매별 추출물은 독성으로부터 안전한 0.05% 이하의 농도에서 melanin 생성을 40% 이상 억제하는 높은 활성을 보여주었다. 이후 우리는 택사 추출물의 MPLC분리 분획을 실시하여 세 가지 분획을 얻었으며 이들을 대상으로 세포 손상 회복시험과 melanin생성 억제 시험, 염증인자 생성 억제 시험을 실시하였다. 그 결과 분획물들 중 3번 분획물이 세포 손상 회복을 30% 이상 올려주는 좋은 결과를 보여주었고, melanin 생성 억제 시험과 COX-2 생성억제에서도 주목할만한 결과를 보여주었다.

• Geomechanics and Engineering
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• 제12권3호
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• pp.523-539
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• 2017

Clay soils are typical for their swelling properties upon absorption of water during rains and development of cracks during summer time owing to the profile desorption of water through the inter-connected soil pores by water vapour diffusion leading to evaporation. This type of unstable soil phenomenon by and large poses a serious threat to the strength and stability of structures when rest on such type of soils. Even as lime and cement are extensively used for stabilization of clay soils it has become imperative to find relatively cheaper alternative materials to bring out the desired properties within the clay soil domain. In the present era of catastrophic environmental degradation as a side effect to modernized manufacturing processes, industrialization and urbanization the creative idea would be treating the waste products in a beneficial way for reuse and recycling. Bottom ash and ecosand are construed as a waste product from cement industry. An optimal combination of bottom ash-eco sand can be thought of as a viable alternative to stabilize the clay soils by means of an effective dispersion dynamics associated with the inter connected network of pore spaces. A CATIA model was created and imported to ANSYS Fluent to study the dispersion dynamics. Ion migration from the bottom ash-ecosand pile was facilitated through natural formation of cracks in clay soil subjected to atmospheric conditions. Treated samples collected at different curing days from inner and outer zones at different depths were tested for, plasticity index, Unconfined Compressive Strength (UCS), free swell index, water content, Cation Exchange Capacity (CEC), pH and ion concentration to show the effectiveness of the method in improving the clay soil.

• Asian Pacific Journal of Cancer Prevention
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• 제17권sup3호
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• pp.245-252
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• 2016

Due to increasing incidence of breast cancer, recognition of risk factors has become increasingly important. Over the past few decades, among risk factors of this disease, stressful life events have attracted particular attention, but their relationship with breast cancer incidence and survival remains a mystery. This study aimed to examine the relationship between severe stressful life events and incidence and survival of women with breast cancer. In this case-control study, using a structured telephone interview with 355 women with breast cancer and also with 516 women with benign breast diseases who were matched in demographic characteristics, necessary information about the experience of major stressful events in the years before the diagnosis were collected. Data were analyzed using statistical methods of ${\chi}^2$, t, and Kaplan-Meier with a significance level of <0.05. Generally, in the case and control groups, there were no significant association between experience of stressful life events and incidence of breast cancer. Regarding associations between each of the events and incidence of breast cancer only "severe interpersonal problems with spouse" was significant. In the breast cancer group, even after controlling confounding variables, there was no significant association between major stressful events and disease-free survival, or overall 5-and 10-year survival. In this study, only "severe interpersonal problems with spouse" was confirmed as a risk factor. This result can be useful in developing preventive policies. More research regarding the interactive effects of psycho-social factors in the incidence and survival of breast cancer with stressful life events is recommended.

• 성인간호학회지
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• 제20권5호
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• pp.791-803
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• 2008

Purpose: The purpose of this study was to collect basic data in the quality of life related to health in migrant workers. Methods: Data from 133 migrant workers was collected from August to December 2007 using a questionnaire from two free clinics located in Seoul and Gyeonggi-do. The data was scored by mean and standard deviation. Differences were evaluated according to the subjects' general characteristics by the t-test and the ANOVA test. The relationships in the quality of life related to health between the 9 sub-scales were evaluated by the Pearson's correlation coefficient. Results: 1) Total average score of migrant workers' quality of life related to overall health is $61.09{\pm}13.68$. The score of the quality of life related to physical health is $64.39{\pm}15.21$ and the quality of life related to mental health is $57.80{\pm}16.18$. 2) With respect to the general characteristics of subjects, the quality of life related to health was significantly different in age(F=3.852, p=.013), especially in physical health(F=6.868, p=.000). 3) The relationship between physical health and mental health was significant(r=.663, p=.000). Conclusion: Program development to improve quality of life related to health for migrant workers is needed.

• Asian Pacific Journal of Cancer Prevention
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• 제16권3호
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• pp.915-921
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• 2015

Context: In the last half century, discovering, developing and introducing of clinical agents from marine sources have seen great successes, with examples including the anti-cancer compound trabectedin. However, with increasing need for new anticancer drugs, further exploration for novel compounds from marine organism sources is strongly justified. Objective: The major aim of this study was to evaluate the antitumor and antioxidant potential of Sargassum tenerrimum J.Agardh (Sargassaceae) on Ehrlich ascites carcinoma (EAC) in Swiss albino mice. Materials and Methods: An ethanol extract of S. tenerrimum (EEST) from whole algae was used to evaluate cytotoxicity followed by in vivo assessment of toxicity, using biochemical parameters including hepatic and non-hepatic enzymes. Antioxidant properties were examined in animals bearing EAC treated with daily oral administration of 100-300 mg/kg extract suspension. Results: Antitumor effects of EEST in EAC bearing mice was observed with LD50 1815 mg/kg. Parameters like body weight, tumor volume, packed cell volume, tumor cell count, mean survival time and increase in life span in animals in the EAC bearing animals treated with EEST 300 mg/kg was comparable with control group. Significant differences were also seen with changes in total protein content, hepatic enzymes contents, MDA level, and free radical scavenging enzymes in untreated vs. EEST treated group animals. Conclusions: Evaluation of antioxidant enzymes and hepatic enzymes in the EAC animal model treated with EEST exhibited similar effects as the positive control drug 5-flurouracil. S. tenerrimum extracts contain effective antioxidants with significant antitumor activity.

• Parasites, Hosts and Diseases
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• 제51권3호
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• pp.335-341
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• 2013

Balamuthia mandrillaris is one of the 4 amebas in fresh water and soil that cause diseases in humans. Granulomatous amebic encephalitis (GAE), caused by B. mandrillaris, is a rare but life-threatening condition. A 4-year-old, previously healthy, Thai girl presented with progressive headache and ataxia for over a month. Neuroimaging studies showed an infiltrative mass at the right cerebellar hemisphere mimicking a malignant cerebellar tumor. The pathological finding after total mass removal revealed severe necrotizing inflammation, with presence of scattered amebic trophozoites. Cerebrospinal fluid (CSF) obtained from lumbar puncture showed evidence of non-specific inflammation without identifiable organisms. A combination of pentamidine, sulfasalazine, fluconazole, and clarithromycin had been initiated promptly before PCR confirmed the diagnosis of Balamuthia amebic encephalitis (BAE). The patient showed initial improvement after the surgery and combined medical treatment, but gradually deteriorated and died of multiple organ failure within 46 days upon admission despite early diagnosis and treatment. In addition to the case, 10 survivors of BAE reported in the PubMed database were briefly reviewed in an attempt to identify the possible factors leading to survival of the patients diagnosed with this rare disease.

• 한국의류학회지
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• 제16권3호
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• pp.233-242
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• 1992

This study primarily concentrates on the Fashion Style of the New Generation which has come into being in 1980 with reference to the contents of the newspaper and magazine in 1950's. . The New Generation has undergone the social and cultural change under the effect of mass communication, mass consumption brought by the economic development, sports boom promoted during the period of Asian Games and Seoul Olympic Games and the adoption of the policy for the autonomous school uniform. In the process of the social and cultural change, they have the common peculiarity such as sensitivity, anthoritarianism and polarity and they have taken an important part in the development of the 'Young Fashion' The characteristics of their fashion styles are divided into three periods as follows; 1. The rising period (1980-1982): The most important pecuriality of the first step can be sum up to the following point. The free fashion style replaced the formal one such as T-shirt or casual wear comes into as a everyday dress. Moreover, many people become interested in the New Fashion which is gradually diversified and high-qualified. As a natural consequence, the lively interest of the people has brought into the appearance and competition of the New Brand in fashion industry 2. The growing period (1983-1986): Mannish Look, so-called 'New Fashion' gained the summit of the fashion and change over conservatively. However, 'Mannish Look' have great effect on the Fashion Style until now on. Specially in Korea, 'Punk Style'and 'Androgynous Look' can be an example among many. 3. The diversifying period (1987-1989): The Fashion Style has developed variously even though the Reactionism takes the lead as the main current of the Korean Fashion. Moreover, it is noticeable that man comes into the stage as a new fashion group and the fashion market begins to dear in various lines of goods with moderate and low prices. These various aspects can be regarded as diversification in the Fashion Style as the needs in the times and society.

• 한국수소및신에너지학회논문집
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• 제12권3호
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• pp.177-189
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• 2001

T hydrogen absorption-desorption behavior induced by thermal or hydrogen pressure cycling in a closed system was observed in hydrogen storage alloys, $(La-R-Mm)Ni_{4.5}Fe_{0.5}$, $MmNi_4Fe_{0.85}Cu_{0.15}$ and $(Ce-F-Mm)Ni_{4.7}Al_{0.2}Fe_{0.1}$. Thereby (La-R-Mm), Mm and (Ce-F-Mm) refer to La-rich mischmetal, mischmetal and Ce-free mischmetal respectively. As the results, it is found that the alloy stabilities during thermal cycling varies with alloy composition change. The highest stability occurs in $MmNi_4Fe_{0.85}Cu_{0.15}$ and the lowest stability in $(La-R-Mm)Ni_{4.5}Fe_{0.5}$. Comparing hydrogen pressure cycling with thermal cycling, pressure cycling causes severer degradation of the alloy $(Ce-F-Mm)Ni_{4.7}Al_{0.2}Fe_{0.1}$ than thermal cycling. When the 1500 times-cycled alloy is annealed at $400^{\circ}C$ for 3hrs under 1 atm of hydrogen pressure the hydrogen storage capacity is recovered only partially but not completely to the initial capacity. The amount of capacity loss after annealing is larger in the hydrogen pressure cycled samples than in the thermal cycled, suggesting an incoming of impure gas during hydrogen pressure cycling.

• 농업과학연구
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• 제25권2호
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• pp.293-309
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• 1998

This study is aimed at identifying the decision making criteria as B/C ratio, IRR and NPV based on the expected benefits and costs of the land utilization and promotion projects which have implemented to improve agricultural structure under WTO system. To carry out the objectives of the study, Sinseok project area located at Dangjin district, Chungnam province was selected. Sinseok project area has 306.2 ha of paddy area with 172 farm households. The project area will be operated by the 33 specialized farm households after completion of the project which will have 20 years of economic life. After completion of the project, farm size will be increased from 1.8ha to 9.3ha. Land intensity of the project area will be increased by 10%. Increase of land productivity and cost saving due to the labor saving technology as farm mechanization will be expected. According to the survey results, the annual amount of production cost savings per farm was estimated 3.884million won and increased total farm income was expected about 43.8million won per year. The total expexted project benefits was expected 174million won per year. The project costs to promote land utilization and structural change consisted of handling charges, and direct payment for land movility. The decision making criteria representing economic feasibility of the project such as B/C ratio, NPV and IRR were estimated 2.49, 483million won and 30% respectively when the cut-off rate was taken into account 10%. In conclusion, the land utilization and promotion project proppeled by the Korean Government under the agricultural land law is considered economically feasible from the view points of expected project benefits and costs. Accordingly the project have to be implemented more strongly under the G't financial support considering WTO and UR negociation which were aimed at achieving the free trade and improvement of international competitiveness of farm products.