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Preventing of Bone Loss in Ovariectomized Rats by Salvia miltiorrhiza Radix Root Extract

  • Park, Sung-Hye
    • Preventive Nutrition and Food Science
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    • v.10 no.2
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    • pp.156-160
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    • 2005
  • Salvia miltiorrhiza Radix root extracts (SMR) was evaluated for inhibition of the progress of bone loss induced by ovariectomy (OVX) in rats. We measured body weight and bone histomorphometry in sham, OVX and SMR-administered OVX rats. From light microscopic analyses, porous or erosive appearances were observed on the surface of trabecular bone of tibia in OVX rats, whereas those of the same bone in sham rats and in SMR-administered rats were composed of fine particles. The trabecular bone area and trabecular thickness in OVX rats were decreased by $50\%$ from those in sham rats, and these decreases were completely inhibited by administration of SMR for 7 weeks. In this study, the mechanical strength in femur neck was significantly enhanced by the treatment of SMR for 7 weeks. In OVX rats, free $T_3$ was normal in all cases, whereas free $T_4$ was significantly increased. Although there was no difference between OVX and SMR-administered rat in $T_3$ levels, we have found significant difference between them in $T_4$ level. These results strongly suggest that SMR may be beneficial for preventing bone loss in OVX rats.

A retrospective comparison of 3 approaches of vestibuloplasty around mandibular molar implants: apically positioned flap versus free gingival graft versus modified periosteal fenestration

  • Lee, Won-Pyo;Lee, Kyoung-Hoon;Yu, Sang-Joun;Kim, Byung-Ock
    • Journal of Periodontal and Implant Science
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    • v.51 no.5
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    • pp.364-372
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    • 2021
  • Purpose: This study aimed to clinically evaluate the efficacy of vestibuloplasty around lower molar implants using 3 different modalities: apically positioned flap alone (APF), APF with a free gingival graft (FGG), and APF with modified periosteal fenestration (mPF). Methods: Three different vestibuloplasty procedures during second-stage implant surgery were performed at the mandibular molar area in 61 patients with a shallow vestibule and insufficient keratinized tissue (KT). The clinical measurements of KT width were recorded at baseline, immediately after surgery (T0), 6 months after surgery (T6), and 12 months after surgery (T12). Soft tissue esthetic scores were measured. Results: An additional KT width gain from baseline to T12 of approximately 2 mm was obtained with FGG and mPF compared to that with APF. Shrinkage of the re-established tissue was lower with mPF and FGG than with APF, whereas the esthetic profile was better with APF and mPF than with FGG. Conclusions: Within the limitations of this study, mPF showed potential as a promising approach for vestibuloplasty around the lower molar implants compared to the traditional APF and FGG.

The Radiation Spot Size due to Wiggler Errors in a Free-Electron Laser Oscillator

  • Nam, Soon-Kwon;Park, Y.S.
    • Journal of the Korean Physical Society
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    • v.73 no.10
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    • pp.1495-1501
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    • 2018
  • We have developed an extended three-dimensional free-electron laser (3D FEL) code with source-dependent expansion to calculate the intensity of the radiation field and the spot size in a free-electron laser oscillator. The effect of the wiggler field errors was evaluated for the case of a planar wiggler generated by a magnet stack with parabolic shaped pole faces by using the extended three-dimensional equations in a free-electron laser oscillator based on the proposed FEL facility which is to be operated in the far-infrared and the infrared regions. The radiation spot size due to the wiggler field errors also have been analyzed for wiggler errors of ${\Delta}B/B=0.0$, 0.03, 0.06 and 0.09% at z = 1 m and z = 2 m. The effect of the diffraction of radiation field due to the wiggler field errors of ${\Delta}B/B=0.0$ and ${\Delta}B/B=0.09%$ at 200 passes was evaluated by using the extended 3D code that we developed. The variation of the curvature of the phase front and the effect of the radiation field intensity due to the wiggler field errors were also evaluated for B = 0.5 T and B = 0.7 T with the wiggler error of ${\Delta}B/B=0.09%$ at 200 passes and the results were compared to those of without errors. The intensity of the radiation, behavior of the radiation spot size and the variation of the curvature of the phase were highly sensitive to the wiggler error of ${\Delta}B/B$ > 0.09%, but were less sensitive to the wiggler errors for ${\Delta}B/B$ < 0.09% in a free-electron laser (FEL) oscillator based on the proposed FEL facility.

Effect of Zona Hardening on In Vitro Fertilization in Mouse Oocytes I. Analysis of Zona Soluble Properties with Proteolytic Enzymes (생쥐난자에 있어서 투명대 경화 현상이 체외수정에 미치는 영향 I. 단백분해효소에 의한 투명대의 용해성 분석)

  • 이상진;이상민;지희준;장경환;정형민;이훈택;정길생
    • Korean Journal of Animal Reproduction
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    • v.17 no.2
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    • pp.93-101
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    • 1993
  • These experiments were carried out to investigate whether zona hardening affect the efficiency of in vitro fertilization in mouse oocytes. The soluble properties for zona pellucida of oocytes matured in vivo, aged oocytes, and ovarian oocytes matured in vitro have been analyzed with proteolytic enzyme, 3mg/ml of $\alpha$-chymotrypsin. The mean solubility(t50) for the zona of unfertilized oocytes, oocytes not fertilized at the first inseminati and in vitro produced zygotes were 10.1, 20.3 and 32.3min., respectively. The t50 for zona lysis of fertilized oocytes was significantly difference than those observed for unfertilized oocytes and oocytes not fertilized at the first insemination(P<0.01). In addition, the t50 of zona in ovulated oocytes with and without cumulus cells incubated for 0, 3, 6, 9 and 12 hr in vitro, t50 were 13.9, 11.1, 20.7 and 28.0min., and 22.3, 21.0, 30.0 and 33.5min., respectively. In these experiments, the zona pellucida showed a gradual increase in resistance to dissolution by $\alpha$-chyjotrypsin with in vitro aging for more than 6 hrs. This effect was greater in cumulus-free as compared to cumulus-intact oocytes. Finally, in cumulus-intact and cumulus-free ovarian oocytes matured for 0, 5, 10 and 15 hr in vitro the t50 of zona pellucida were 3.0, 10.6, 18.4 and 24.5 min., and 3.0, 14.0, 26.2 and 32.0 min., respectively. Clear differences in solubility between the zona pellucida of oocytes matured in vivo and in vitro. This data were found suggest that under in vitro conditions there is a gradual change in the soluble properties of the zona pellucida, particularly in the absence of the cumulus cells.

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Combination effects of nitrite from fermented spinach and sodium nitrite on quality characteristics of cured pork loin

  • Kim, Tae-Kyung;Lee, Mi-Ai;Sung, Jung-Min;Jeon, Ki-Hong;Kim, Young-Boong;Choi, Yun-Sang
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.10
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    • pp.1603-1610
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    • 2019
  • Objective: The purpose of this study was to investigate the effect of fermented spinach derived nitrite and sodium nitrite on cured pork loin. Methods: The following treatments were prepared using brine (8% [w/v] salt): Control (-), no nitrite added; Control (+), 0.08% (w/v) sodium nitrite brine; T1, 0.04% (w/v) nitrite fermented spinach juice in 0.04% (w/v) sodium nitrite brine; T2, spinach juice in 0.04% (w/v) sodium nitrite brine; T3, 0.04% (w/v) nitrite fermented spinach juice used as sodium nitrite free brine; and T4, spinach juice used as sodium nitrite free brine. T2 and T4 were incubated to allow to reduce nitrate to nitrite. Results: Spinach juice did not affect cooking loss and pH but negatively influenced flavor and overall acceptability (p<0.05). T1 samples containing synthetic and natural nitrites showed the highest redness values. Spinach juice negatively affected volatile basic nitrogen; however, thiobarbituric acid reactive substance values of T1 and T3 were similar to those of controls (+) (p>0.05). Residual nitrite content decreased with decreasing synthetic nitrite levels. T1 and control samples showed no significant differences in overall acceptability (p>0.05). Conclusion: Thus, combined synthetic and natural nitrites improved the quality of cured pork loin.

Compositions of Fatty Acid, Free Amino Acid and Total Amino Acid of Lespedeza x chiisanensis T. LEE (지리산 싸리의 지질 구성 지방산과 유리 아미노산 및 구성 총 아미노산 조성에 관하여)

  • 김종균
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.22 no.5
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    • pp.586-591
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    • 1993
  • The compositions of amino acid in the protein and fatty acid in the lipid of Lespedeza x chiisanensis T. LEE were analyzed by HPLC and GC, respectively. The contents of crude oil and protein from the extracts were 11.13% and 5.18%, respectively. The amount of free anino acids in the protein was 443.14mg/100g, and 94.84mg/100g of essential amino acid were contained in the free amino acid. The amount of total amino acids in the protein was 3159.85mg/100g, and 1068.18mg/100g of essential amino acid were contained in the total amino acid. The compositions of fatty acid in the lipid were $C_{18\;:\;2}=45.05%,\;C_{18\;:\;3}=18.71%,\;C_{19}=14.70%,C_{18\;:\;1}=6.81%,\;C_{16}=4.35%,\;C_{16\;:\;1}=1.59%$ in order, respectively. 72.44% of unsaturated fatty acids were contained in the lipid.

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Improved nonlinear modelling approach of simply supported PC slab under free blast load using RHT model

  • Rashad, Mohamed;Yang, T.Y.
    • Computers and Concrete
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    • v.23 no.2
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    • pp.121-131
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    • 2019
  • Due to the heterogeneity nature of the concrete, it is difficult to simulate the hyperdynamic behaviour and crack trajectory of concrete material when subjected to explosion loads. In this paper, a 3D nonlinear numerical study was conducted to simulate the hyperdynamic behaviour of concrete under various loading conditions using Riedel-Hiermaier-Thoma (RHT) model. Detailed calibration was conducted to identify the optimal parameters for the RHT model on the material level. For the component level, the calibrated RHT parameters were used to simulate the failure behaviour of plain concrete (PC) slab under free air blast load. The response was compared with an available experimental result. The results show the proposed numerical model can accurately simulate the crack trajectory and the failure mode of the PC slab under free air blast load.

Preliminary Studies on the Measurement of the Free Thyroxine in the Serum by the Radioimmunoassay (방사면역측정법(放射免疫測定法)에 의한 혈중(血中) 유리(遊離) Thyroxine 농도측정(濃度測定)에 대(對)한 기초적(基礎的) 검토(檢討))

  • Lee, Joon-Il
    • Journal of radiological science and technology
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    • v.10 no.1
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    • pp.85-90
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    • 1987
  • Preliminary studies on the measurement of the free thyroxine in the serum with Amerlex $FT_{4}$ RIA kit were investigated using a tracer as $^{125}I-T_{4}$ derivative which is not almostly bound to thyroxine binding globulin, etc. The results are followed: 1. Linearity was tested on standards at various concentrations, and reproducibility and accuracy was excellent. 2. The antibody specificity is also excellent, and standard calibration curve of total $T_{4}$ was similar that of adding the TBG inhibitor. 3. Each value of $T_{4}$ in serum (the normal group, the hypothyroidism patients the pregnant women and the TBG dificiency patients) was not significant. As mentioned above, this method is more simple and rapid, compared to the other method.

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Free sugar distribution in ginseng plant and change of it's content in the root with dehydration (인삼부위별 및 건조온도에 따른 유리당의 함량변화)

  • 김해중;조재선
    • Journal of Ginseng Research
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    • v.7 no.1
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    • pp.44-50
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    • 1983
  • This study was conducted to investigate distribution of free sugas in the ginseng plant and change of free sugar content in dried ginseng with various drying conditions. The results obtained are as follows: 1. The total free sugar content is about 1% in the root and about 2% in the upland portions. Sucrose which accounts 80% in those free sugars, is 0.91% in main body 0.90% in raw ginseng, 0.74% in latheral root, 0.67% in head, 0.57% in skin, 0.64% in leaves, and 0.35% in steins. 2. Sucrose content is 3.3~4.6% in the ginseng root dried at temperature of 3$0^{\circ}C$ and 0.5 ~ 1% in the root dried it at temperature of 50-9$0^{\circ}C$. 3. Maltose was not present in fresh ginseng or dried ginseng which was dried under the t, but it was produced dried at the temperature above 5$0^{\circ}C$, it was 0.5% at 5$0^{\circ}C$, 1.49 %. at 7$0^{\circ}C$, and 4.03% at 9$0^{\circ}C$, respectively. This sugar Height be produced by endogenous saccharifying enzymes.

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Effects of Oxygen Annealing on the Structural Properties and Dielectric Properties Of Bi4Ti3O12 Thin Films (Bi4Ti3O12 박막의 구조적 특성과 유전 특성에 미치는 산소 열처리 효과)

  • Cha, Yu-Jeong;Seong, Tae-Geun;Nahm, Sahn;Jeong, Young-Hun;Lee, Young-Jin;Paik, Jong-Hoo
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.22 no.4
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    • pp.290-296
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    • 2009
  • $Bi_{4}Ti_{3}O_{12}$ (BiT) thin films were grown on the Pt/Ti/$SiO_2$/si substrate using a metal organic decomposition (MOD) method. Effects of oxygen annealing on the structural properties and dielectric properties of the BiT thin films were investigated. The BiT films were well developed when rapid thermal annealed at $>500^{\circ}C$ in oxygen ambient. For the film annealed at $700^{\circ}C$, no crystalline phase was observed under oxygen free annealing atmosphere while its crystallinity was significantly enhanced as the oxygen pressure increased. The BiT film also exhibited a smooth surface with defect free grains. A high dielectric constant and a low dielectric loss were achieved satisfactory in the frequency range from 75 kHz to 1 MHz. Especially, the BiT film, annealed at $700^{\circ}C$ and 10 torr oxygen pressure, showed good dielectric properties: dielectric constant of 51 and dielectric loss of 0.2 % at 100 kHz. Its leakage current was also considerably improved, being as $0.62\;nA/cm^2$ at 1 V. Therefore, it is considered that the oxygen annealing has effects on an enhancement of crystallinity and dielectric properties of the BiT films.