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The Effect of Low Molecular Weight Heparin on Groin Flap Transplantation in Rat (저분자량 헤파린이 쥐 서혜부 유리피판 이식술에 미치는 영향)

  • Lee, Jun-Mo;Lee, Gang-Wook;Lee, Dong-Geun
    • Archives of Reconstructive Microsurgery
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    • v.2 no.1
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    • pp.77-81
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    • 1993
  • Free tissue transplantation is commonly performed with the brilliant achievement in microsurgery and anticoagulants and antithrombotic agents have been prescribed in the procedures. However, there is no clean-cut indication as to which agents would be more effective in every steps and final consequences. Low molecular weight heparins inhibiting coagulation in plateletrich plasma and acting on the vascular endothelium have antithrombotic and fibrinolysis action. The experiment with rat groin free flap transplantation after 6-hour ischemia and injection of the low molecular weight heparin was performed and the results between the injection and non-injection group were analysed as follows, 1. Both of the 24-hour groups, vessel patency was not proportional to color change of the groin flap. 2. On the second day after anastomois, heparin-injection group showed intact intima, patent lumen without thrombus, and mild granulomatous inflammation around the suture material and control group with doubtful patency revealed intimal loss and thrombus formation. 3. On the 5th, 7th, and 9th postoperative day, heparin group was patent in anastomosis and showed acute inflammatory cells. 4. The 7th-week period, heparin-injection group showed intact flap color, patent lumen with intact intima and persistent foreign body granuloma.

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Effects of dietary Cadmium and Protein Levels on the Body Protein Metabolism and Cadmium Toxicity in Growing Rats (식이내 Cadmium과 단백질 수준이 흰쥐의 체내 단백질 대사 및 Cadmium 중독에 미치는 영향)

  • 이혜영
    • Journal of Nutrition and Health
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    • v.21 no.6
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    • pp.410-420
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    • 1988
  • This study were performed to investigate effect of dietary cadmium(Cd) and protein levels on growth, body protein metabolism and Cd toxicity in growing rats. Forty eight male rats of Sprague-Dawley weighing 113$\pm$2g were blocked into 6 groups accoridng to body weight. Dietary protein were given at the levels of 7, 15 and 40% of diet and Cd (200ppm)were either added or not. The result obtained were summerized as follow; 1) Food intake, weight gain, FER PER, liver and kidney weight, weight and length of bones, hematocrit, and hemoglobin content in Cd-added groups were low than those in Cd-free groups. 2) Serum total protein showed no significant difference with Cd addition, but it was significantly lower in low protein diet groups. Liver protein in Cd-added groups was lower than Cd-free groups, and was tend to be increased with increasing dietary protein level. 3) Daily urinary and fecal nitrogen excretions in Cd-added groups were lower than Cd-free groups, and were increased with increasing dietary protein level. 4) Cadmium contents in blood, liver, kidney, and femur were tend to be decreased with increasing dietary protein level. Especially, Cd content in kidney of Cd-added groups was significantly decreased with increasing dietary protein level. 5) Daily urinary and fecal Cd excretions were tend to be increased with increasing dietary protein level, and Cd-added-high protein diet group showed the highest Cd excretion among the Cd-added groups, Cd absorption ration and Cd retention ratio were tend to be decreased with increasing dietary protein level.

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The Effects of Daecheongryoung-tang on Anti-weight Gain and Anti-hyperlipidemic in Obese Sprague Dawley Rat Induced by High Fat Diet (대청룡탕이 비만 유도 흰쥐의 체중 감량과 혈중지질농도 개선에 미치는 영향)

  • Cho, Eun Jin;Yang, Seung Jeong;Cho, Seong Hee
    • Journal of Korean Medicine for Obesity Research
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    • v.18 no.1
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    • pp.27-35
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    • 2018
  • Objectives: The aim of this study is to investigate the effects of Daecheongryoung-tang (DCR) therapy on body weight, serum total cholesterol, high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol, triglyceride, free fatty acid, total lipid, phospholipid level and complete blood cell count of obese rats. Methods: 34 rats are divided into 4 groups, the rats in the normal group are 7 and the rats in the other group are 9 per group; Normal group (general fat diet and no medication), Control group (high-fat diet and no medication), DCR_L group (high-fat diet and DCR 250 mg medication) and DCR_H group (high-fat diet and DCR 500 mg medication). DCR is administrated for 6 weeks. Results: There is significant statistical difference between Control group and DCR-H group for the body weight, the total cholesterol, LDL cholesterol, triglyceride, free fatty acid level. Also, there is significant statistical difference among Control group, DCR_L group and DCR_H group for body weight, triglyceride, free fatty acid and phospholipid level. Conclusions: These results suggest that medication of DCR_L and DCR_H is effective for the treatment of obesity.

The Relationship Between Body Composition and Bone Mineral Density in Postmenopausal Women (폐경 후 여성에서 체성분과 골밀도와의 관계)

  • Chae, Jin-Wook;Kim, Il-Hoe;Kwon, Woo-Sung;Lee, Keun-Mi;Jung, Seung-Pil;Moon, Yong
    • Journal of Yeungnam Medical Science
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    • v.20 no.1
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    • pp.53-61
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    • 2003
  • Background: Body weight is an important factor that influence the bone density in postmenopausal women except estrogen dificiency. However, different results are reported about the relationship between body composition and bone density in the postmenopausal women. We have studied the relationship between age, body weight, body mass index (BMI), waist hip ratio (WHR), muscle mass, fat mass, fat free mass and bone density. Materials and Methods: We have studied 127 persons of postmenopausal women who visited university medical center and examined the inbody 3.0 and Dual Energy X-ray Absorptiometry (DEXA) from Jan, 2001 to Jun, 2002. they didn't have any disease and didn't received hormone therapy, osteoporosis therapy or other medication that influence the bone density. Results: The numbers of study subjects is total 127 persons. Mean age is $56.9{\pm}5.14$, mean weight is $59.3{\pm}8.7kg$, mean BMI is $25.37{\pm}3.16(kg/m^2)$, mean fat mass is $20.02{\pm}5.05kg$, mean muscle mass is $37.49{\pm}4.50kg$, mean fat free mass is $39.80{\pm}4.70$, mean BMD is $0.828{\pm}0.148(g/cm^2$). In the result of linear regression analysis, age, height, weight, muscle mass, fat free mass, fat mass, BMI are significant determinants of BMD. In stepwise multiple regression analysis, age is the most significant determinant of BMD and besides age, fat free mass is the most significant determinant of BMD among body composition. Conclusion: In postmenopausal women, age, height, weight, BMI, muscle mass, fat free mass, fat mass are significant determinants of BMD and besides age, fat free mass is the most significant determinant of BMD among the body composition. So, diet and exercise that increase fat free mass will contribute to bone density increment.

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An Experimental Study on the Slamming impact around Wedged type structure in accordance with the Weight and Height of the change (중량 및 높이변화에 따른 쐐기형 구조물 주위의 슬래밍 충격에 관한 실험적 연구)

  • Oh, Seung-Jin;Jo, Dae-Hawn
    • Journal of Navigation and Port Research
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    • v.39 no.1
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    • pp.77-82
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    • 2015
  • Slamming means that the hull hits the waves and receives impact pressure. This slamming effect may cause harm to people and when you put the hull at risk. so it is very harmful for cargo safety. Therefor slamming impact pressure should be fully considered in ship designing. In this study the model of wedged type structure are produced aimed to simulate a free fall that the experiments were carried out on different weight and free fall height. The flow field has been obtained by 2-frame grey level cross correlation PIV(Particle Image Velocimetry) method and experiment was divided into water entry and water exit. The impact pressure of free fall structure by a pressure acquisition system apply to dewetron system. The angles between a model and the water surface are adapted $15^{\circ}$ respectively. The weight change of models was given as 1.5, 1.8 and 2.0kg. To study slamming phenomenon for free fall height the experiments were carried out by the free fall height of 100, 200 and 300mm. The experimental value of the impact pressure according to the changes in weight was increase impact pressure in proportion to the increase in weight and higher free falling height has also influenced the increase in impact pressures.

Growth and Yield of Peanuts Affected by Weeding Time and Periods in Bare Soil and Under the P. E. film Mulch (노지(露地) 및 P. E. film 피복하(被覆下)에서 제초시기(除草時期)와 기간(期間)이 땅콩의 생육(生育) 및 수량(收量)에 미치는 영향(影響))

  • Kang, K.H.;Lee, S.S.;Lee, K.H.;Hwang, H.B.;Lee, S.B.;Ye, B.D.
    • Korean Journal of Weed Science
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    • v.7 no.1
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    • pp.52-57
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    • 1987
  • To know the effects of weeding periods (weeding from 12 days, 28 days and 42 days after seeding to harvest, and weeding from seeding to 14 days, 28 days and 42 days after seeding) and growing conditions such as transparent polyethylene film mulch (P.E. mulch) and bare soil on growth and yield of peanuts, "Yeongho-Tangkong" was planted on May 10, 1984. Under P.E. mulch, the number of weeds was higher, but the weed dry weight was lower than in bare soil by the middle of July. Sixty days after seedings, the length of main stems in weedy check plots was longer, but shoot dry weight was lower compared to weed free plot. In the correlation coefficients between weed dry weight and the shoot dry weight of peanut on July 14, the growth retardation of peanuts due to weeds was showed earlier under P.E. mulch than in bare soil. Shoot dry weight, shelling ratio, number of seeds per pod, 100 pod weight, and seed yield were higher under P.E, mulch compared to bare soil. But weed dry weight, length of branches, number of pod bearing branches, number of pods per square meters, and pod yield were similar between P.E. mulch and bare soil. Shoot dry weight of peanuts, length of branches, number of pod bearing branches, number of pods per square meters, pod yield, 100 pod weight, 100 seed weight, and seed yield in weed free plots from 28 days after seeding to harvest (28 DAS-Harvest) were higher compared to weed free plots from 42 DAS-Harvest. However, in the weed free plot from seeding to 42 days after seeding seed yield was lower than that of the continuous weeding plot due to lower number of pod bearing branches and number of pods per square meters. When weed was not controlled at the later growth stages of peanuts, reduction in seed yield due to weeds was greater in bare soil than that under P.E. mulch.

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A Nutritional Survey on Korean Women Workers through Their Body Fat (일부직장여성(一部職場女性)의 체지방량(體脂肪量) 측정(測定)에 의(依)한 영양실태조사(營養實態調査))

  • Kim, Jung-Sook;Sung, Nak-Eung
    • Journal of Nutrition and Health
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    • v.5 no.2
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    • pp.83-89
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    • 1972
  • A survey on the nutritional state was conducted from June 11 to Nov. 30, 1971, on 673 women workers $(16{\sim}25\;yrs)$ Jorking in a factory of food industry. Total body fat content was measured by skin-fold thickness (S. F. T.) with caliper at three region of the body. And it was calculated by regression equation, with the following conclusions were abtained. 1. The mean with standard deviation body height and weight of the Korean women workers were $155.0{\pm}4.21\;cm$ and $50.1{\pm}5.31\;kg$; respectively. 2. Their mean skin-fold thickness with their standard deviation triceps region of upper arm, 14.3{\pm}3.42$; Subscapular region, $18.0{\pm}5.57mm$; Abdominal region, $19.3{\pm}4.87mm$ and total aveager, 17.2{\pm}3.91mm$. 3. The body fat contents according to body fat weight regression equation were;fat weight. 10.7 kg; fat-free weight, 39.4kg; fat weight/ fat-free weight, 27.5%; fat-free mass/ total body mass 77.6%, and fat weight/ total body mass,21.6%. 4. Since the sknin-fold thickness between the triceps and upper abdominal region and between the former and Subscapular region were correlated with the coefficients of 0.838 and 0.615 respectively. and the following regression equations were established. a) S. F. T. of Subscapular region $(mm)=0.929{\times}$S. F. T. of triceps region (mm)+4.707. b) S. F. T. of Abdominal $region(mm)=1.24{\times}$S. F. T. of triceps region(mm)+1.50. Nutritional survey on the women workers in a fact ory of food industry, performed as above by the S. F. T. method, elucidated the fact that their nutritional state is as good as the control healthy female, and that their energy uptake may well be said to be satisfactory.

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Effects of Acanthopanax Sessiliflorus $S_{EEM}$ Ethyl Alcohol Extract on the Body Weight and Serum Lipid Level in Mice (오가피 에탄올 추출물이 마우스의 체중 및 혈청내 지질 함량에 미치는 효과)

  • Kim, Young-Kun;Cho, Su-In;Kim, Hyung-Woo;Jeon, Byung-Gwan;Jeong, Hyun-Woo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.2
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    • pp.352-357
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    • 2006
  • This experimental study was designed to investigate the effects of Acanthopanax sessiliflorus $S_{EEM}$ leaves, stems, roots (ACL, ACS, ACR) on the change of weight and the serum total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, free fatty acid, total lipid and phospholipid level in obese mice induced Dy high fat diet. Experimental groups were as follows ; Normal group was fed with normal diet and administered with distilled water during 7 weeks, Control group was fed with high fat diet and administered with distilled water during 7 weeks, Sample A group was fed with high fat diet and administered with ACL of 500 mg/kg/mouse/day during 7 weeks, Sample B group was fed with high fat diet and administered with ACS of 500 mg/kg/mouse/day during 7 weeks, Sample C group was fed with high fat diet and administered with ACR of 500 mg/kg/mouse/day during 7 weeks. The results were as follows ; 1. Sample A group, Sample B group and Sample C group were significantly decreased the serum total lipid level in comparison with Control group. 2. Sample A group was decreased the body weight (4 weeks, 7 weeks), the serum total cholesterol level, the serum LDL-cholesterol level, the serum triglyceride level, the serum free fatty acid and phospholipid level but increased the serum HDL-cholesterol level in comparison with Control group. 3. Sample B group was increased the serum HDL-cholesterol level but decreased the body weight (4weeks), the serum total cholesterol level, the serum free fatty acid and triglyceride level in comparison with Control group. 4. Sample B group was significantly decreased the body weight (7 weeks), the serum LDL-cholesterol and phospholipid level in comparison with Control group. 5. Sample C group was increased the serum HDL-cholesterol level but decreased the body weight (4 weeks) and the serum free fatty acid level in comparison with Control group. 6. Sample C group was significantly decreased the body weight (7 weeks), the serum total cholesterol level, the serum LDL-cholesterol and triglyceride level in comparison with Control group. According to above results, I suggest ACR is able to be used for the obesity.

Wax Gourd Reduces Adipose Depots and Fat Cell Sizes without Affecting the Levels of Leptin in Rats Fed Medium Fat

  • Kang Keum-Jee
    • Nutritional Sciences
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    • v.9 no.3
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    • pp.173-178
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    • 2006
  • The purpose of this study was to investigate the effects of wax gourd on body weight, body fat, triglyceride, leptin and fat cell size in rats fed medium fat Male Sprague Dawley rats were fed with experimental diet containing total dietary fat at 20% of calorie with wax gourd (WG) for 4 weeks. Forty rats were divided into 4 groups including control, 5, 10, and 15% (w/w) WG supplement The results showed that weight gain was significantly higher in 5% WG than that in control (p<0.05), but was not different among the WG supplement groups. Total fat weight was significantly decreased in both 10 and 15% WG supplement groups than that of control. The levels of triglycerides and free fatty acids in the plasma were significantly decreased, particularly in 15% WG supplement group (p<0.05). The levels of leptin was not significantly different among the experimental groups. Fat cell size was significantly decreased in WG supplement groups compared to that of control group (p<0.05). Correlation among the parameters demonstrated that weight gain correlated positively with total fat weight, the levels of leptin and triglycerides. Taken these results together, 15% WG supplement diet substantially reduces total fat weight, triglycerides and free fatty acids levels and fat cell size in the rat fed midium fat.

A mesh-free analysis method of structural elements of engineering structures based on B-spline wavelet basis function

  • Chen, Jianping;Tang, Wenyong;Huang, Pengju;Xu, Li
    • Structural Engineering and Mechanics
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    • v.57 no.2
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    • pp.281-294
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    • 2016
  • The paper is devoted to study a mesh-free analysis method of structural elements of engineering structures based on B-spline Wavelet Basis Function. First, by employing the moving-least square method and the weighted residual method to solve the structural displacement field, the control equations and the stiffness equations are obtained. And then constructs the displacement field of the structure by using the m-order B-spline wavelet basis function as a weight function. In the end, the paper selects the plane beam structure and the structure with opening hole to carry out numerical analysis of deformation and stress. The Finite Element Method calculation results are compared with the results of the method proposed, and the calculation results of the relative error norm is compared with Gauss weight function as weight function. Therefore, the clarification verified the validity and accuracy of the proposed method.