• Journal of Chest Surgery
• /
• v.23 no.4
• /
• pp.617-621
• /
• 1990

A heart supplies blood of about 15, 000 liters to each human organ in a day. A normal function of heart valves is necessary to accomplish these enormous work of heart. The disease of heart valve develops to a narrowness of a closure, resulting in an abnormal circulation of blood. In an attempt to eliminate the affliction of heart valves, the operative method to replace with artificial heart valves has developed and saved numerous patients over past 30 years. This replacement operation has been performed since early 1960`s in Korea, but all the artificial heart valves used are imported from abroad with very high costs until recent years. New artificial heart valves have been developed in Korea Advanced Institute of Science and Technology since early 1980`s. The first developed valve was designed with a free-floating pyrolytic carbon disk that is suspended in a titanium cage. The design of the valve was tested in vitro, and in animals in 1987. The results from this study was that the eccentrically placed struts creates a major and minor orifice when the disc opens and stagnation of flow in the area of the minor orifice has led to valve thrombosis. In this work, the design of the valve was changed from a single - leaflet valve to double - leaflet one in order to resolve the problems observed in the first - year tests. Morphological and hemodynamic studies were made for the newly designed valves through the in vitro and in vivo tests. The design and partial materials of the artificial heart valve was improved comparing with first - year`s model. The disc in the valve was modified from single - leaflet to bi - leaflet, and the material of the cage was changed from titanium metal to silicon - alloyed pyrolytic carbon. A test was made for the valve in order to examine its mechanical performance and stability. Morphological and hemodynamic studies were made for the valve that had been implanted in tricuspid position of mongrel dogs. All the test animals were observed just before the deaths. A new artificial heart valve was designed and fabricated in order to resolve the problems observed in the old model. The new valve was verified to have good stability and high resistance to wear through the performance tests. The hemodynamic properties of the valve after implantation were also estimated to be good in animal tests. Therefore, the results suggest that the newly designed valve in this work has a good quality in view of the biocompatibility. However, valve thrombosis on valve leaflets and annulus were found. This morphological findings were in accordance with results of surface polishing status studies, indicating that a technique of fine polishing of the surface is necessary to develop a valve with higher quality and performance.

• Journal of Korea Water Resources Association
• /
• v.38 no.10 s.159
• /
• pp.871-883
• /
• 2005

This paper investigates the impacts of turbulent anisotropy on the mean flow and turbulence structures in vegetated open-channel flows. The Reynolds stress model, which is an anisotropic turbulence model, is used for the turbulence closure. Plain open-channel flows and vegetated flows with emergent and submerged plants are simulated. Computed profiles of the mean velocity and turbulence structures are compared with measured data available in the literature. Comparisons are also made with the predictions by the k-$\epsilon$ model and by the algebraic stress model. For plain open-channel flows and open-channel flows with emergent vegetation, the mean velocity and Reynolds stress profiles by isotropic and anisotropic turbulence models were hardly distinguished and they agreed well with measured data. This means that the mean flow and Reynolds stress is hardly affected by anisotropy of turbulence. However, anisotropy of turbulence due to the damping effect near the bottom and free surface is successfully simulated only by the Reynolds stress model. In open-channel flows with submerged vegetation, anisotropy of turbulence is strengthenednear the vegetation height. The Reynolds stress model predicts the mean velocity and turbulence intensity better than the algebraic stress model or the k-$\epsilon$ model. However, above the vegetation height, the k-$\epsilon$ model overestimates the mean velocity and underestimates turbulence intensity Sediment transport capacity of vegetated open-channel flows is also investigated by using the computed profiles. It is shown that the isotropic turbulence model underestimates seriously suspended load.

• Journal of Korea Water Resources Association
• /
• v.43 no.9
• /
• pp.801-811
• /
• 2010

A three-dimensional numerical model called NEWTANK is employed to investigate solitary wave run-up with an internal wave-maker on a steep slope. The numerical model solves the spatially averaged Navier-Stokes equations for two-phase flows. The LES (large-eddy-simulation) approach is adopted to model the turbulence effect by using the Smagorinsky SGS (sub-grid scale) closure model. A two-step projection method is adopted in numerical solutions, aided by the Bi-CGSTAB (Bi-Conjugate Gradient Stabilized) method to solve the pressure Poisson equation for the filtered pressure field. The second-order accurate VOF (volume-of-fluid) method is used to track the distorted and broken free surface. A solitary wave is first internally generated and propagated over a constant water depth in the three-dimensional domain. Numerically predicted results are compared with analytical solutions and numerical errors are analyzed in detail. The model is then applied to study solitary wave run-up on a steep slope and the obtained results are compared with available laboratory measurements.