• Biomolecules & Therapeutics
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• v.19 no.1
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• pp.90-96
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• 2011

Automated HPLC/SPE/HPLC coupling experiments using the Sepbox system allowed the rapid identification of four bioactive principles reducing the production of amyloid $\beta$-peptide ($A{\beta}$) from two South African plants, Euclea crispa subsp. crispa and Crinum macowanii. The structures of biologically active compounds isolated from the methanol extract of Euclea crispa subsp. crispa were assigned as 3-oxo-oleanolic acid (1) and natalenone (2) based on their NMR and MS data, while lycorine (3) and hamayne (4) were isolated from the dichloromethane-methanol (1:1) extract of Crinum macowanii. These compounds were shown to inhibit the production of $A{\beta}$ from HeLa cells stably expressing Swedish mutant form of amyloid precursor protein (APPsw).

• The Korean Journal of Health Service Management
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• v.7 no.4
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• pp.33-47
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• 2013

The purpose of this study is to identify the important factors of education service quality and to develop the evaluation instrument in learning facilities for care workers. This study was processed as four steps. First, the important factors were confirmed through literature reviews and the expert board discussions. Second, the evaluation instrument was developed and validity & reliability of the instrument were checked by factor analysis and Cronbach's ${\alpha}$. Lastly, the instrument was rechecked by the expert board in language usages and importance of the items. The results indicated that the important quality factors were divided with infrastructure and service process. Especially, the process contained providing appropriate education information & counseling, providing appropriate contract & paying fees, keeping specified service principles and so on. The study instrument was developed with 28 items. This instrument will be helpful to improve the education service quality. Besides, the staffs must continuously try to improve and manage their education services using the results of this kind of evaluation instrument.

• Journal of radiological science and technology
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• v.43 no.5
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• pp.367-374
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• 2020

The purpose of this study is to understand the infection prevention system and infection management perception of Ultrasound diagnostic room in medical institutions by sonographer's in general practitioner, semi and general hospitals. As a research method, a statistical analysis was conducted by surveying a total of 20 items in four category to determine the infection perception of sonographer's according to gender, age, working institution, and working period. As a result of infection awareness, males were in the ultrasound gel management category, women were in the transducer management category, all age groups were in the transducer management system category, and the General Practitioner, semi and general hospitals. were in the transducer management system category, and general hospitals showed a high degree of infection awareness in the category of disinfection and sterilization, and in the category of transducer management in the entire working period. In the results of the analysis of the correlation between the sub-factors of the perception of infection control in the Ultrasound diagnostic room the degree of correlation between each category showed a middle degree correlation(r>0.5) and a significant difference by category(p<.01). In conclusion, the prevention of infection in the ultrasound diagnostic room, which sonographer's firms think, was found to be the most efficient ultrasound diagnostic room infection control to implement transducer and gel management in accordance with the principles of disinfection and sterilization.

• Journal of Korea Game Society
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• v.12 no.4
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• pp.3-12
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• 2012

This study discusses how players make the mutually cooperative mechanism in Social Games. In SNG, many players exchange helps each other. That mechanism is not only one-off but also repetitive process. In the perspective of reciprocity in Evolutionary psychology and Mythology, this study analyzes mutual cooperation in several game texts most well known in the SNG field. According to the field study results, four cooperative mechanisms were extracted. These 4 principles apply to every digital game design for emerging of cooperative storytelling among players.

• Proceedings of the KOSOMBE Conference
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• v.1995 no.05
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• pp.173-178
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• 1995

This paper relates the occidental constitutional theory to the oriental one, concluding their origins to be similar, and demonstrates a new method of constitutional diagnosis by O-Ring Measurement System Of Muscular Meridians and Laser Constitutional Diagnosis. It establishes Laser Constitutional Diagnosis(L.C.D) using laser beams according to the principles of acupuncture and Sa-Sang constitutional physiology under the effect of spatial morphological energy of geometric isomers. Finally, hypothetical theory of L.C.D. was experimented by the O-Ring Measurement Systems of Muscular Meridians(O-R MSMM). O-R MSMM has been specially devised to improve the manual O-Ring Test prevailing to distinguish energetic response by muscle tonicity. Statistically, it has been proved that the constitutional diagnosis with O-R MSMM was highly effective and objective in the clinical experiences.

• YAKHAK HOEJI
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• v.37 no.2
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• pp.143-148
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• 1993

The objective of this study was to evaluate the sedative activity of four aporphine alkaloids (APA) and nine cyclopeptide alkaloids(CPA), which had been isolated from the seeds (sanjoin) of Zizyphus vulgaris var. spinosus, and the fruits and stem bark of Zizyphus jujuba var. inermis. The assessment of sedative activity was carried out, employing a hexobarbital-induced sleeping time method in mice. When the relative sedative potency of sanjoinine-A(CPA) was given as one unit, those of nuciferine (APA), lysicamine (APA), chlorpromazine (positive control), and sanjoinine -Ahl (an epimer of sanjoinine-A) were 13, 6.5, 5, and 3, respectively. The sedatvie activities of other CPAs were much lower than those of sanjoinine-A and -Ahl, and other APAs were not active. On heat treatment, nuciferine and lysicamine were degraded into some artifacts which exhibited no sedative activity, while sanjoinine-A was converted into sanjoinine-Ahl which showed more potent sedative activity. These results suggested that nuciferine and sanjoinine-A were major sedative components of native sanjoin, and that sanjoinine-A and its epimeric artifact, sanjoinineAhl were the active principles of roasted sanjoin. It provides a scientific basis for heat-processing (roasting) of this Oriental medicine.

• Journal of the Korean housing association
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• v.25 no.4
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• pp.1-9
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• 2014

The post-war period has witnessed the emergence of new towns in a number of countries in Southeast Asia. New town development started in Malaysia with Petaling Jaya as a satellite town in 1953 to accommodate the rapid growing population of Kuala Lumpur. New towns have been designed in accordance with the British town planning principles, based on the modern ideal city. Nonetheless, they have constituted a regional character as they have incorporated local factors such as local technologies as well as site and climatic conditions. In the shaping of the new towns in modern cities, regulatory aspects have played important roles. The regulations decide the basic framework for planning of new town, block plan and unit plan. The ultimate goal of this study is to understand the identity of the new town planning of Malaysia. As a first step, we reviewed the local regulations, standards, and design guidelines which are applicable to the new town planning from the national land use to local plans. As a result, we categorized the guidelines into four areas: urban space, site plan, street system, block plan and unit plan. We expect this study to provide the framework of the Malaysia's new town planning from the perspective of the local regulations.

• Korean Institute of Interior Design Journal
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• v.23 no.4
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• pp.42-51
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• 2014

The research aims to analyze the structural meaning of mobility design on 'Furnitecture' with the works of Andrea Zittel. The study consists of the literature review and the analysis of Zittel's works. The framework for the analysis is divided into four steps: identification of visual forms/structure/function, analysis of the principles of delivering the concept of mobility, interpretation & synthesis of the relational meanings derived from the concepts of mobility, and evaluation of Zittel's tendency toward design/social background/design history, etc. Total fifteen cases are selected from Zittel's works, and each case is analyzed following the above steps. The finding shows that Zittel likes to play with geometrical forms, grid & modular system to create a minimum space for living equipped with critical furnishing. Secondly, Zittel's works deliver the concept of mobility by applying movability, adaptation, combination and transformation. Thirdly, through the concepts of mobility, Zittel reflects the ideas of high efficiency and functionalism, harmony with natural environment, search for liberty, simple & humble life and success of the designers of American modernism. Finally, it is found that modernism from the era of Bauhaus, utopian values derived from constructionism, utilitarianism inspired by Shakers and homestead act & mobile home/capsule unit suggested since 19th century in America mainly affect Zittel's works to reflect the dynamic concepts of mobility through the design of furnitecture.

• The Transactions of the Korea Information Processing Society
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• v.3 no.6
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• pp.1355-1364
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• 1996

A complex object model is one of the value based data model which extends the existing relational data model for supporting complex structured data. This paper studies a method for designing algebra for the complex object model. For this some others' algebra supporting complex objects are compared and analysed in terms of the applicability of a algebraic optimization strategics. The complex object algebra is designed, based on four principles, simple and clear definitions, no restriction on input data, single specification system. The central nature of this paper is to keep the basis of algebraic optimization method through simplicity, safety and the applicability of algebraic optimization strategy. Finally, it shown that the designed algebra has the equivalent or enhanced expressability with other's algebra.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1978.06a
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• pp.8.4-9
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• 1978

Since the first success of simple mastoidectomy, about 100 years ago by Schwartze (1873). Zollner (1951) and Wullstein (1952) had formulated systemically the basic principles of restorative surgery of chronic ear diseases. Although the last century has shown a remarkable advances in surgical technique, there are still lots of debatable problems yet. The authors experienced 970 cases of middle ear surgery during last four years and clinical and statistical analysis were done as a preliminary report.