• 제목/요약/키워드: forsythia

검색결과 216건 처리시간 0.035초

의성개나리 과피(果皮) 성분(成分)의 항진균작용(抗眞菌作用)에 관한 연구(硏究)(I) (Antifungal Studies on Components from the Pericarp of Forsythia viridissima (I))

  • 노영수
    • 생약학회지
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    • 제6권3호
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    • pp.143-147
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    • 1975
  • The antifungal studies on the triterpenoids from the pericarp of Forsythia viridissima LINDL. were conducted. The pericarp was obtained from the plant which was cultivated at Eusung, Kyungsang-bukkdo, Korea. Substances A and B were isolated by column fractionation and purified by recrystallization. Antifungal actions of substance A, acetyloleanolic acid, show significant inhibition effect against Trichophyton rubrum, T. mentagrophytes, T. tonsurans, Microsporum nanum, M. canis, and M. cookei. Substance B, viridissimic acid, shows negative effect against Candida albicans and shows lower effects against other test fungi.

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한국산 물푸레나무과의 분계적 분석 (A Cladistic Analysis of the Korean Oleaceae)

  • 이상태
    • Journal of Plant Biology
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    • 제25권2호
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    • pp.57-64
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    • 1982
  • In order to elucidate the intergeneric relationshiops within Korean Oleaceae including the endemic Abeliophyllum distichum, 19 species and 9 varieties of 9 genera were investigated. A cladistic analysis based on 18 characters revealed close relationships among (1) Osmanthus, Chiononthus, Fraxinus, (2) Abeliophyllum, fontanesia, Forsythia, and (3) Ligustrum, Syringa, and well accorded with the pollen morphological result. Jasminum was connected to the branch of Ligustrum possibly owing to a sampling error. A hypothesis on the origin of Abeliophyllum was drawn that it originated from Fontanesi or less probably from the common ancestor of Fontanesia and Forsythia.

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한약재 열수 추출물의 변이원 및 항변이원 활성의 검색 (Screening of the Mutagenicity and Antimutagenicity of the Hot Water Extracts from Medicinal Plants)

  • 정주은;강미영;남석현
    • Applied Biological Chemistry
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    • 제42권4호
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    • pp.344-350
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    • 1999
  • 130종의 식물성 한약재에서 제조한 열수 추출물의 변이원성, 항변이원성 및 세포독성을 측정하였다. 세포내재성 alkaline phosphatase의 활성을 지표로 한약재가 지시세포인 E. coli PQ37의 성장에 미치는 영향을 조사한 결과, 연교(Forsythia koreana Nakai)를 포함한 14종류의 시료자체에서 세포독성이 강하게 나타난 반면, 속단(Phlomis umbrosa Turcz.)등 22종의 시료에서는 세포성장을 촉진하는 활성이 나타났다. SOS chromotest기법을 이용하여 한약재가 가지는 변이원성 및 항변이원성을 조사한 결과, 연교(Forsythia koreana Nakai)와 황련(Coptis japonica Nakai)을 포함한 36종의 시료에서 돌연변이를 유발시키는 능력이 나타난 반면, 산사(Crataegus pinnatifida Bunge)를 포함한 12종의 한약재에서 뚜렷한 항변이원 활성이 검정되었다.

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연교 (Forsythia Viridissima Lindl.) 추출물이 고콜레스테롤 식이 흰쥐 간조직의 항산화계와 지질과산화에 미치는 영향 (Effect of Forsythia Viridissima Extracts on Antioxidative System and Lipid Peroxidation of Liver in Rats Fed High-Cholesterol Diet)

  • 이정민;최상원;조성희;이순재
    • Journal of Nutrition and Health
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    • 제36권10호
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    • pp.990-996
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    • 2003
  • This study was conducted to investigate the effects of Forsythia viridissima Lindl. (FVL) on antioxidative defense system and lipid peroxidation of liver in rats fed high-cholesterol diet. Sprague-Dawley male rats weighing 100 $\pm$ 10 g were randomly assigned into five experimental groups fed 0.5% cholesterol ; HC group which was not supplemented FVL extract, 0.05% methanol extract diet group (MSI group), 0.1% methanol extract diet group (MS2 group), 0.025% ethylacetate-souble fraction diet group (ES1 group) and 0.05% ethylacetate-souble fraction diet group (ES2 group). Experimental diets were fed ad libitum to the rats for 3 weeks. The hepatic xanthine oxidase (XOD) activity in the MS2 group was decreased to 20% as compared to HC group. The activities of hepatic superoxide dismutase (SOD) and catalase (CAT) were not significantly different among all the high cholesterol diet groups. The hepatic glutathione peroxidase (GSHpx) activity in MS2, ES2 groups were significantly increased as compared to HC group. The hepatic glutathione S-transferase (GST) activity in the MS2 group was increased to 20% as compared to HC group. The levels of hepatic TBARS in the MS1, MS2, ES1 and ES2 groups were reduced by 13%, 21%, 13% and 21%, respectively, as compared with HC group. The contents of lipofuscin in liver tissue was not significantly different among all the experimental groups. The results indicate that FVL extract may reduce oxidative damage by activating antioxidative defense system of liver in rats fed high-cholesterol diets.

數種의 韓藥 抽出物이 抗알레르기 反應에 미치는 影響 (The study on the anti-allergic effect of a number of herb-extract.)

  • 노태석;노석선
    • 한방안이비인후피부과학회지
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    • 제15권1호
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    • pp.1-30
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    • 2002
  • This experimental study was done to research effects of a number of extract on the anti-allergic effect. The results were obtained as follows: 1. In effect of herb-extract on compound $\frac{48}{80}$-mediated histamine release from Evans blue skin assay, Isatis Japonica Miquel, Dictamnus dasycarpus Turcz, Spirodela polyrhiza, Cimicifuga heracleifolia, Bupleurum chinense, Magnolia liliflora, Forsythia koreana, Aster tataricus L., Xanthium strumarium L.(MtOH), Trichosanthes kirilowii, Phellodendron amurense Rupr, Schizonepeta tenuifolia Var, Betula platyphylla show considerable visible anti-allergic effect. In the result of quantification of histamine induced compound $\frac{48}{80}$, Spirodela polyrhiza, Isatis Japonica Miquel, Trichosanthes kirilowii, Bupleurum chinense, Forsythia koreana inhibit histamine release effectively. 2. In effect of Herb-Extract on compound $\frac{48}{80}$-mediated histamine release from RPMC, Spirodcla polyrhiza, Cimicifuga heracleifolia inhibit histamine release effectively. 3. In effect of Herb-Extract on anti-DNP IgE-mediated histamine release from Evansblue skin assay. Spirodela polyrhiza, Cimicifuga heracleifolia(0.1mg/ml). Forsythia koreana, Aster tataricus L., Xanthium strumarium L.(0.1mg/ml), Trichosanthes kirilowii(0.1mg/ml) show considerable visible anti-allergic effect. In the result of quantification of histamine induced anti-DNP IgE, Spiradela polyrhiza, Isatis Japonica Miquel, Trichosanthes kirilowii, Bupleurum chinense, Forsythia koreana inhibit histamine release effectively 4. In the result of genetic manifestative inhibition about the human mast cell-1(HMC-1), Cimicifuga heracleifolia has considerable effect in IL-4 in IL-5, and Tussilage farfara L. has in IL-4. According to the above results, it is suggested that several Herb-Extract have anti-allergic effect.

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개나리국의 종간교잡에 관한 연구 (STUDIES ON THE INTERSPECIFIC CROSSING OF GENUS FORSYTHIA)

  • HARN, Chang Yawl
    • Journal of Plant Biology
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    • 제4권1호
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    • pp.1-7
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    • 1961
  • 분류학에서 이종으로 취급되고 있는 Forsythia속의 종간교잡을 실시하여 화주장의 분리비, 양화주간의 수정양식, $F_1$의 임성, ♀♂성 기타 분류학상의 제문제제를 구명한바 그 요지는 다음과 같다. (1) 화주장은 L:S=1:1로 분리한다. (2) 이종간의 적, 부적법수분인데도 양친 L, S의 수정양식은 일 일반형예식물 동일종내의 2형화와 전혀 동일하다. (3) $F_1$의 L, S간의 수정양식도 일반형예식물과 동일하다. (4) 종간교잡은 잘되고 $F_1$의 임성도 이상없다. (5) 교잡제일식의 형태, 생리적변이는 심하다. (6) S주도 적법수분에서는 임성이 양호하고 Forsythia가 ♀, ♂ 이주라는 것은 잘못이다. (7) $F_1$에는 영양생장 및 생식기관이 빈약한 왜형이 나타난다. (8) 본실험에 사용한 두종은 이종이라기보다 동일종내의 이화형개체라고 하는 것이 타당하다.

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Study of Oral Microbial Prevalence and Oral Health in Adults

  • Moon, Kyung-Hui;Lee, Jin-Young;Kang, Yong-Ju
    • International Journal of Clinical Preventive Dentistry
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    • 제14권4호
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    • pp.264-270
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    • 2018
  • Objective: This study performed a quantitative analysis using the real-time polymerase chain reaction technique to examine the oral microbial prevalence in adults and intended to examine the correlations between risk factors of periodontal disease and oral bacteria and correlation between oral test scores and oral microorganisms. Methods: We examined papillary marginal attached (PMA) index, modified patient hygiene performance (M-PHP) index, probing depth (PD), modified gingival index, and oral bacteria counts and surveyed 117, 20 years or older adult males and females who visited dental clinics in the Daejeon region to analyze the prevalence and oral health. Results: The prevalence was 100% for Fusobacterium nucleatum, meaning it was observed in all examined subject, 85.5% for Parvimonas micra, 76.1% for Prevotella intermedia, and 72.6% for Tannerella forsythia. The averages of P. gingivalis and T. forsythia increased as the examined subjects were older, and there was a statistically significant difference between T. forsythia and E. nodatum in relation to medical history, between P. intermedia and P. micra in relation to gender, and between P. intermedia and E. corrodens in relation to smoking (p<0.05). For a correlation between the oral test scores and oral microorganisms, P. gingivalis and F. nucleatum was highly correlated with PD (correlation coefficient of 0.51 and 0.41) (p<0.01) while P. gingivalis, P. micra, C. rectus, and E. nodatum were significantly correlated with M-PHP index, gingival index, PD, and PMA index (p<0.01, p<0.05). Conclusion: For oral health management of adults, the age, systemic disease, and smoking are closely related to oral bacteria, and P. gingivalis, T. forsythia, F. nucleatum, P. intermedia, P. micra, C. rectus, E. corrodens, and E. nodatum are considered to be the oral microorganisms that indicate periodontal health.

Subgingival pathogens in chronic periodontitis patients affected by type 2 diabetes mellitus: a retrospective case-control study

  • Montevecchi, Marco;Valeriani, Leoluca;Gatto, Maria Rosaria;D'Alessandro, Giovanni;Piana, Gabriela
    • Journal of Periodontal and Implant Science
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    • 제51권6호
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    • pp.409-421
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    • 2021
  • Purpose: The aim of this study was to compare the prevalence and bacterial load of 6 main periodontal pathogens between pairs of periodontal patients with and without type 2 diabetes mellitus. Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans genotypes were also investigated. Methods: Twenty patients affected by chronic periodontitis and type 2 diabetes were retrospectively selected and matched to 20 patients without diabetes on the basis of the degree and severity of periodontal disease. Microbiological data of subgingival biofilms were analysed and compared for the examined pathogens: A. actinomycetemcomitans, P. gingivalis, Prevotella intermedia, Treponema denticola, Fusobacterium nucleatum, and Tannerella forsythia. Results: The pairs were balanced in terms of demographic and clinical parameters, except for bleeding on probing and suppuration. In the microbiological test sites (4 for each patient), the mean probing pocket depth was 6.34±1.63 mm in patients with diabetes and 6.41±1.78 mm in patients without diabetes. No significant difference between pairs in the prevalence of P. gingivalis or the distribution of its genotypes was recorded. Patients with diabetes had a significantly greater amount of total bacterial load, P. gingivalis, T. denticola, T. forsythia, and F. nucleatum (P<0.05). Moreover, patients with diabetes had a higher number of sites with a greater cell count than patients without diabetes. When compared to the total bacterial load, only T. forsythia maintained its relative load in patients with diabetes (P=0.001). Conclusions: This retrospective matched study supports the hypothesis that microbiological differences exist among periodontal patients with and without diabetes mellitus.

세포학적 형질에 기초한 미선나무의 계통분류학적 연구 (A systematic study of Abeliophyllum distichum (Oleaceae) based on cytological characters)

  • 태경환;도재화;김주환
    • 식물분류학회지
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    • 제35권2호
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    • pp.143-151
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    • 2005
  • 한국 특산식물인 미선나무 1종을 대상으로 세포학적 조사를 수행한 결과 2n=28로 x=14의 2배수성 식물로 조사되었다. 염색체 크기는 $1.00{\mu}m$에서 $2.03{\mu}m$의 크기를 보였고, 그 크기는 연속적인 상태를 나타내었다. 본 연구에서 밝혀진 세포학적 형질인 기본염색체수, 크기의 연속성, 배수성 및 핵형에 있어 개나리속 식물과 거의 유사한 특징을 갖는 것으로 밝혀져 이들 속간에 세포학적으로 유연관계가 밀접한 것으로 판단되며, 미선나무속과 개나리속은 동일족에 포함되는 것이 타당할 것으로 사료된다.