• Journal of the Korean association of regional geographers
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• v.12 no.1
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• pp.59-71
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• 2006

The purpose of this study is to explain the regional transformation in the lowest level administration district(Myeon). The major factor of regional transformation is the change of geographical range, identity of place name, the formation and change of regional center. Jo-Chon Myeon as a sample study region is located in near Jeon-Ju city. The large and dynamic city in neighbor is strong influenced to the change of geographical range. But the place name has Identity in spite of the regional change. The formation of new regional center is influenced by new road, rail road and station, japanese large farm, administration office in this district.

• Korean Journal of Food Science and Technology
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• v.39 no.5
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• pp.541-545
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• 2007

The potential to produce biogenic amines was investigated in microbial strains isolated from fermented soybean paste, cheonggukjang. The typical levels of 11 biogenic amines, including putrescine, histamine, and tryptamine, were analyzed in commercial cheonggukjang. The tyramine and histamine levels in the samples ranged from 4.2 to 483.1 mg $kg^{-1}$ and 0.2 to $70.3mg\;kg^{-l}$, respectively. A total of 4 microbial strains of Bacillus sp. were isolated from cheonggukjang. The Bacillus sp. were identified as B. amyloliquefaciens, B. subtilis, and B. licheniformis based on phenotypic characteristics, which included using the VITEK system. The screening plate method for detecting amino acid decarboxylase positive microorganisms was performed. The results fer amino decarboxylation were positive, and biogenic amine formation was evaluated by the confirmation of amine-forming capacity.

• Journal of Korean Society of Rural Planning
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• v.21 no.2
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• pp.177-188
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• 2015

This research was establishment of landscape formation plan to Yusang village region Yeongcheon city. Literature research, field research, surveys carried out for this purpose. In addition, by utilizing design code that appears in the common characteristics of the rural scenic views of the region in improving the quality of life of the local population and preserve the indigenous landscape as well as improve the quality of rural landscapes, management, capital town of the region to form Yeongcheon the center was established in the landscape plan form. The natural environment of the capital region for the landscape formation plan, Humanities and Social Environment, Landscape Resources Status, Social Consciousness, landscape map, landscape design, code identification and basic design and planning through the basic steps to derive design guidelines were applied to the landscape formation plan. Formation landscape plan for the regional launch of the regional landscape improvements, region entrance space and yusang reservoirs place, rest zone in the sacred tree and nurse trees around the plan, and repair the town hall. residents living village road maintenance to improve the environment, and develop a detailed plan, such as the lungs maintenance. The plan is likely to be able to contribute to improving the quality of life of the people and landscapes to improve regional, creating a guide for future business landscape is formed to have a significant advantage as a basis.

• Journal of the Korean Regional Science Association
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• v.11 no.2
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• pp.63-86
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• 1995

One of the innovative and most promising approaches to new high-tech business formation from university is technology business incubators, which attempts to enhance small high-tech start-up firms' chances of survival. To date, there is few comprehensive effort to do a comparative study of technology business incubatiors between European Countries and U.S. to evaluate the impacts of them on regional development. With these consideration in mind this research anlayzed key findings of 6 case studies of university related Technology Business Incubators in the U.K., Germany, and U.S. to explore relationship of university to regional development. These included Cambridge Science Park(CSP) '||'&'||' West of Scotland Science Park in the U.K., Dortmund Technologiezentrum '||'&'||' Berlin Technologiezentrum, and Rensselaer Technology Development Center of the Georgia Institute of Technology in the U.S. The primary objective of this study was to advance our understanding of the impact and utility of technology business incubators and to get some policy implications for the future development in this area in Korea. Among the major question examined hear was "how do they contribute the overall economy of the communities in which they are located\ulcorner". The results of the case study about this question were very positive. The technology business incubators contributed to foster new high-tech small business formation from university, to facilitate the cooperation between university and industry and Incubator tenants created jobs and income, pay taxes, and in doing so, had a multiplier effects on the local economy. The same was true of incubator graduates. With this consideration in mind the university related business regioned development policy in korean local communities.

• Journal of the Korean institute of surface engineering
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• v.46 no.1
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• pp.9-15
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• 2013

The effect of the additionally applied electrical current on the adhesion strength between electroless Cu and polyimide films was investigated. Peel tests were performed after applying electrical current within the range from 0.1 to 100 mA for the duration from 1 to 30 minutes. Sample with more than 1 mA of additional electrical current for 1 minute showed higher adhesion strength than that without additional electrical current. However, samples with 10 mA of additional electrical current for more than 10 miniutes showed the degradation of adhesion strength. Ra and RMS values of the peeled polyimide surface were proportional to the adhesion strength though there were no significant changes in the morphology of the peeled surfaces with varied amount and time-length of additional electrical current. Applying electrical current could increase the density of chemical bonding, which results in increase of the adhesion strength between copper and polyimide. However, in the case of applying additional electrical current for excessive amount or time, the degradation of the adhesion strength owing to the formation of copper oxide at the interface could occur.

• Journal of the Korean earth science society
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• v.28 no.5
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• pp.613-619
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• 2007

Mesoscale low is often observed over the downstream region of the East Sea (or, northwest coast off the Japan Islands) during East-Asia winter monsoon. The low system causes a heavy snowfall at the region. A series of numerical experiments were conducted with the aid of a regional model (MM5 ver. 3.5) to examine the formation mechanism of the mesoscale low. The following results were obtained: 1) A well-developed mesoscale low was simulated by the regional model under real topography, NCEP reanalysis, and OISST; 2) The mesoscale low was simulated under a zonally averaged SST without topography. This implies that the meridional gradient of SST is the main factor in the formation of a mesoscale low; 3) A thermal contrast ($>10^{\circ}C$) of land-sea and topography-induced disturbance served as the second important factor for the formation; 4) Paektu Mountain caused the surface wind to decelerate downstream, which created a more favorable environment for thermodynamic modification than that was found in a flat topography; and 5) The types of cumulus parameterizations did not affect the development of the mesoscale low.

• Microbiology and Biotechnology Letters
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• v.43 no.3
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• pp.280-285
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• 2015

Anti-oxidative and anti-inflammatory activities of Cotoneaster horizontalis Decne ethanol extract (CHEE) were evaluated. CHEE possessed a potent scavenging activity against 1,1-diphenyl-2-picryl hydrazyl, which was similar to the activity of ascorbic acid which was used as a positive control. CHEE also effectively suppressed hydrogen peroxide-induced reactive oxygen species on RAW 264.7 cells. Furthermore, CHEE induced the expression of the anti-oxidative enzyme heme oxygenase 1, and its upstream transcription factor, nuclear factor-E2-related factor 2. CHEE inhibited LPS induced nitric oxide (NO) formation as a consequence of inducible NO synthase (iNOS) down regulation. Taken together, these results provide us with an important new insight; that C. horizontalis possesses anti-oxidative and anti-inflammatory activities. Therefore, C. horizontalis may be utilized as a promising material in the field of nutraceuticals.

• Journal of Life Science
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• v.24 no.7
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• pp.713-720
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• 2014

In this study, the antioxidative and anti-inflammatory activities of Ardisia arborescens ethanol extract (AAEE) were evaluated using in vitro assays and a cell culture model system. AAEE exhibited potent scavenging activity against 1,1-diphenyl-2-picryl hydrazyl (DPPH), similar to ascorbic acid, which was used as a positive control. Moreover, AAEE effectively suppressed lipopolysaccharide (LPS)- and hydrogen peroxide ($H_2O_2$)-induced reactive oxygen species (ROS) in RAW 264.7 cells. Furthermore, AAEE induced the expression of antioxidative enzymes, heme oxygenase 1 (HO-1), and thioredoxin reductase 1 (TrxR1), in addition to their upstream transcription factor, nuclear factor-E2-related factor 2 (Nrf2), in a dose-dependent manner. The upstream signaling pathways of mitogen-activated protein kinases (MAPKs) might regulate the modulation of HO-1, TrxR1, and Nrf2 expression. On the other hand, AAEE inhibited LPS-induced nitric oxide (NO) formation, without cytotoxicity. Suppression of NO formation was the result of AEEE-induced down-regulation of inducible NO synthase (iNOS). The suppression of NO and iNOS by AAEE might be modulated by their upstream transcription factor, nuclear factor (NF)-${\kappa}B$, and activator protein (AP)-1 pathways. Taken together, these results provide important new insights into the antioxidative and anti-inflammatory activities of A. arborescens. AAAEE might represent a promising material in the field of nutraceuticals.

• Journal of Life Science
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• v.24 no.9
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• pp.973-980
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• 2014

This study was conducted to explore new nutraceutical resources from the plant kingdom possessing biological activities. To fulfill this purpose, the anti-oxidative and anti-inflammatory activities of Decaisnea insignis ethanol extract (DIEE) were evaluated. First, DIEE possessed potent scavenging activity against 1,1-diphenyl-2-picryl hydrazyl (DPPH), similar to ascorbic acid used as a positive control. Moreover, DIEE inhibited lipopolysaccharide (LPS)- and hydrogen peroxide ($H_2O_2$)-induced reactive oxygen species (ROS) in RAW 264.7 cells. Furthermore, DIEE induced the expression of an anti-oxidative enzyme, heme oxygenase 1 (HO-1), and its upstream transcription factor, nuclear factor-E2-related factor 2 (Nrf2), in a dose-dependent manner. The modulation of the HO-1 and Nrf2 expressions might be regulated by mitogen-activated protein kinases (MAPKs) and their upstream signaling pathways. On the other hand, DIEE suppressed LPS-induced nitric oxide (NO) formation without cytotoxicity. The inhibition of the NO formation was the result of the downregulation of inducible NO synthase (iNOS) by DIEE. The suppression of NO and iNOS by DIEE might be modulated by their upstream transcription factors, nuclear factor ${\kappa}B$ ($NF-{\kappa}B$), and activator protein 1 (AP-1) pathways. Taken together, these results provide important new insights that D. insignis possesses anti-oxidative and anti-inflammatory activities. Therefore, it might be utilized as a promising material in the field of nutraceuticals.

• Journal of the Korean Geographical Society
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• v.37 no.4
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• pp.442-459
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• 2002

With the formation of European Union, the frontier function which was existed among the member nations was vanished. The European Union, each national government, and local or regional self-government search actively for the transfrontier development strategies in order to make the underdeveloped transfrontiers an united internal region of European Union with an augmentation of mutual activities inter-transfrontier and a cooperative development of transfrontier. On the transfrontier among France-Belgium-Luxemburg which was the iron industry center of Europe, the cooperative development strategies(P.E.D.) of the inter-government and inter-local are executing for the restructuring of the stable regional economic on the basis of the INITRREG program of the European Union. In recent years, the locals self-govemments transfrontier are executing not only restructuring of regional economic but formation of urban community with the unification of the urban and regional planning, administration, and society.