• Journal of Korean Ophthalmic Optics Society
• /
• v.21 no.1
• /
• pp.77-81
• /
• 2016

Purpose: This study was performed to investigate the difference of meridional visual acuity and the loss of corrected visual acuity (VA) in order to emphasis the importance of astigmatic correction. Methods: 64 subjects (122 eyes) aged $22.75{\pm}2.36years$ participated in this study. After full correction of astigmatic refractive error, VA was measured in which the direction of the slit filter was matched with astigmatic axis and $90^{\circ}$ to the astigmatic axis. Results: 52 eyes showed no difference in VA between the two direction. However 70 eyes had difference VA between them. 14 out of 52 eyes and 24 out of 70 eyes had under 1.0 in monocular VA. The astigmatic degree was higher in the existence of VA difference between the two direction than non-existence. The difference is higher with under 1.0 monocular VA. Monocular VA is closely related to the focal line having better VA in the principal focal line. Glasses replacement period was analyzed as 6~12 months for the preservation of better VA. Conclusions: The final glasses prescription has to be given with full correction because continued under-correction for astigmatism causes meridional VA difference.

• Journal of Korean Tunnelling and Underground Space Association
• /
• v.23 no.4
• /
• pp.253-263
• /
• 2021

Concrete structures are damaged by aging and external environmental factors. This type of damage is to appear in the form of cracks, to proceed in the form of spalling. Such concrete damage can act as the main cause of reducing the original design bearing capacity of the structure, and negatively affect the stability of the structure. If such damage continues, it may lead to a safety accident in the future, thus proper repair and reinforcement are required. To this end, an accurate and objective condition inspection of the structure must be performed, and for this inspection, a sensor technology capable of detecting damage area is required. For this reason, we propose a deep learning-based image processing algorithm that can detect spalling. To develop this, 298 spalling images were obtained, of which 253 images were used for training, and the remaining 45 images were used for testing. In addition, an improved loss function and data augmentation technique were applied to improve the detection performance. As a result, the detection performance of concrete spalling showed a mean intersection over union of 80.19%. In conclusion, we developed an algorithm to detect concrete spalling through a deep learning-based image processing technique, with an improved loss function and data augmentation technique. This technology is expected to be utilized for accurate inspection and diagnosis of structures in the future.

• Journal of Oriental Neuropsychiatry
• /
• v.16 no.2
• /
• pp.287-299
• /
• 2005

Dissociative disorder is a psychiatric disorder characterized by a sudden loss of memory, but which has no organic disease or explanation. It usually occurs after heavy psychosocial stress or traumatic experience. A transient cerebral ischemic attack (TIA) is an acute episode of temporary and focal loss of cerebral function of vascular origin. TIAs are rapid in onset; symptoms reach their maximal manifestation in fewer than 5 minutes. Manifestations are of variable duration and typically last 2-15 minutes(rarely as long as 24 h). Most TIA durations are less than 1 hour. Of concern is the careful detection of changes in behavior, speech, gait, memory, movement, and vision. TIAs are uncommon in persons younger than 60 years. I treat 6 cases of Sudden Temporary Amnesia Patients with oriental medicine and they are improved. All of them had amnesia for $6{\sim}10\;hours$. During that time, they show behavioral changes and they are not on the state of unconsciousness. After recovery, they also forget what happen at the time. they have some emotional reason too. In conclusion, 4 cases of them belong to dissociative disorder and 2 other cases, TIA.

• Investigative Magnetic Resonance Imaging
• /
• v.22 no.1
• /
• pp.50-55
• /
• 2018

Gelatinous transformation of bone marrow is characterized by hypoplasia of fat cells with focal loss of hematopoietic cells and deposition of extracellular gelatinous substances. It is known to be associated with devastating underlying diseases that starve bone marrow. Here, we present a case of a patient whose magnetic resonance (MR) imaging findings of vertebral column were interpreted as metastasis or hematologic malignancy, however, the final diagnosis revealed a gelatinous transformation of bone marrow. This is the first report of gelatinous transformation of bone marrow without evidence of underlying devastating disease.

• Annals of Clinical Neurophysiology
• /
• v.4 no.2
• /
• pp.98-107
• /
• 2002

Multifocal motor neuropathy (MMN) is a chronic immune-mediated peripheral myelinopathy. The major clinical features include slowly progressive, painless, and asymmetric weakness, usually of distal limb muscle. Early in the course of the disease, weakness is not necessarily associated with muscle atrophy, owing to the initial primary involvement of peripheral myelin. Chronic progressive weakness is often associated with some degree of concurrent axonal loss and subsequent muscle atrophy. Sensory symptoms are usually mild or absent, and involvement of cranial and respiratory muscles is rare. The findings of multifocal motor conduction block, abnormal temporal dispersion, and focal conduction slowing at segments not at risk for common entrapment or compression injury, associated with normal sensory conduction studies along the same segments, are the hallmark electrophysiologic features of MMN. The slow progression and absence of upper motor neuron signs are the major clinical points that separate MMN from amyotrophic lateral sclerosis. The role of GM1 antibodies, found in high titers in 22~84% of MMN patients, remains uncertain. The contention that MMN is an autoimmune disorder is largely based on the often dramatic improvement in symptoms following the administration of intravenuos immunoglobulin or cyclophosphamide.

• The Journal of Internal Korean Medicine
• /
• v.21 no.3
• /
• pp.521-524
• /
• 2000

Wallenberg's syndrome is well known of dorsolateral medullary syndrome. A 56-year-old women was admitted because vertigo, vomitting, vertiginous ataxia, ipsilateral loss Rt. face and Lt. lower limb sense. The result of all performed laboratory tests were normal, but Sr-MRI scan was right lateral medullary infarction. And Br-MRA was focal stenosis of Lt. ICA. We present here one case of Wallenberg's syndrome, who was admitted at Kyungwon University Hospital From 25th Apr. to 21th May. 1998.

• Journal of Veterinary Clinics
• /
• v.21 no.2
• /
• pp.184-186
• /
• 2004

A castrated male, 6 year-old Shih-Tzu, weighing 4.6 kg with a discharge from the external ear canal and a mal-odor was referred to Verterinary Medical Teaching Hospital, Seoul National University. Radiographic findings were narrowing and focal loss of an air density in the left ear canal and bilateral thickening of the osseous bullae. For more detail examination, computed tomography was used. In computed tomographic findings, bilateral thickening of the bulla wall and increased opacity of the bulla space were observed. Thus this dog was diagnosed as bilateral otitis media. Then surgical correction, total ear canal ablation, was performed successfully and the patient showed a good prognosis thereafter. It is considered that computed tomography might serve as an useful imaging tool for otitis media and that it supplies information not obtained with a conventional radiography.

• BMB Reports
• /
• v.49 no.5
• /
• pp.255-262
• /
• 2016

The disease known as cerebral cavernous malformations mostly occurs in the central nervous system, and their typical histological presentations are multiple lumen formation and vascular leakage at the brain capillary level, resulting in disruption of the blood-brain barrier. These abnormalities result in severe neurological symptoms such as seizures, focal neurological deficits and hemorrhagic strokes. CCM research has identified 'loss of function' mutations of three ccm genes responsible for the disease and also complex regulation of multiple signaling pathways including the WNT/β-catenin pathway, TGF-β and Notch signaling by the ccm genes. Although CCM research is a relatively new and small scientific field, as CCM research has the potential to regulate systemic blood vessel permeability and angiogenesis including that of the blood-brain barrier, this field is growing rapidly. In this review, I will provide a brief overview of CCM pathogenesis and function of ccm genes based on recent progress in CCM research.

• Journal of environmental and Sanitary engineering
• /
• v.2 no.2 s.2
• /
• pp.61-67
• /
• 1987

The genus Vibrio contains some of the most important intestinal pathogens of humans, including Vibrio cholerae, the cause of epidemic Asiatic cholera. A group of organisms which have been reffered to as the non-agglutinating vibrio (NAG) do not agglutinate in the Vibrio cholerae 0 group 1 antisera, but are indistinguishable from the 0-1 group both chemically and genetically. Non-O-l Vibrio cholerae can cause isolated as well as focal outbreaks of diarrhea, but the volume of fluid loss does not approach that of classic cholera, and the disease is usually self-limiting. These free-living organisms are found world-widely distributed in the environment including sewage, contaminated water, estuaries, seafood and animals. These strains involved in several cases were isolated from the environment and some patients of diarrhea, and a few epidemiologic reports indicated the wide distribution of the strains throughout the country, giving an attention to the role the organisms may play in an outbreak of diarrhea in Korea. More research on the epidemiology, serologic typing and virulence of the group of organisms, should be, therefore, done to obtain a complete understanding of their role in human disease.

• Journal of the Korean Society of Fisheries and Ocean Technology
• /
• v.30 no.3
• /
• pp.227-236
• /
• 1994

The characteristics of the P(VDF-TrFE) acoustic microscope transducer were evaluated theoretically and experimentally by comparison with those of the PVDF and the ZnO acoustic microscope transducers. It was found that its insertion loss was about 5dB lower than that of the PVDF and about 13$\textbf{dB}$ higher than that of the ZnO. And its relative bandwidth was 20% which could produce the effective acoustic pulse waves having about 4 periods duration into water. Another finding was that the effective horizontal focusing resolution and the focal depth were $120\mu m and $1.5mm$, respectively.