• Journal of Society of Preventive Korean Medicine
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• v.27 no.2
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• pp.23-33
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• 2023

Objectives : Sojadodamgangki-tang and its main components are traditional korean medicinal methods for treatment of cough, sputum and dyspnea. Using a respiratory inflammatory model, we intend to reveal the anti-inflammatory effect and its immune mechanism of Sojadodamgangki-tang. Methods : We used a papain-induced respiratory inflammatory mouse model. 8-week-old female BALB/C mice were divided into 3 groups as follows: the following groups: saline control group, papain treated group (vehicle), papain and Sojadodamgangki-tang(200 mg/kg) treated group (n=4). To evaluate the anti-inflammatory effect of Sojadodamgangki-tang extracts, inflammatory cell infiltration was measured in bronchoalveolar lavage fluid (BALF) and nasal lavage fluid (NALF). In addition, the effects of Sojadodamgangki-tang extracts on Th2 cell population in lung were determined by using flow cytometry. Results : Sojadodamgangki-tang extracts administration reduced inflammatory cell infiltration in BALF and NALF, especially of eosinophils. Furthermore, total immunogloblin (Ig)-E levels was reduced in BALF and serum by drug administration. Interestingly, Sojadodamgangki-tang extracts treatment also decreased the Th2 cell (CD4⁺GATA3⁺) population in lung. Conclusions : Our findings indicate Sojadodamgangki-tang extracts have anti-inflammatory effects by mediating Th2 cell and B cell activation.

• Resources Recycling
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• v.32 no.2
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• pp.33-42
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• 2023

Metal emulsions have been studied for several decades as a method of increasing the efficiency of the steelmaking process. This study was performed using a water model, observable at room temperature, to compensate for the disadvantages of the high-temperature experiment, the results of which are difficult to observe visually. As a substitute for metal-in-slag emulsions, experiments were conducted by dropping distilled water into silicone oil and comparing the results with the results of a calculation by momentum balance equations. The descending velocity of the water droplet decreased as the diameter of the droplet and viscosity of the fluid (silicon oil) increased. To simulate the descending velocity of a water droplet in silicon oil under stirring conditions, the flow rate of the fluid (silicon oil) was measured by particle image velocimetry (PIV) methods. The calculation of the descending velocity of the water droplet was in good agreement with the measured values, with and without stirring a viscous silicone oil.

• 한국전산유체공학회:학술대회논문집
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• 2009.04a
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• pp.290-297
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• 2009

A two-phase (gas and liquid) flow analysis solver, named CUPID, has been developed for a realistic simulation of transient two-phase flows in light water nuclear reactor components. In the CUPID solver, a two-fluid three-field model is adopted and the governing equations are solved on unstructured grids for flow analyses in complicated geometries. For the numerical solution scheme, the semi-implicit method of the RELAP5 code, which has been proved to be very stable and accurate for most practical applications of nuclear thermal hydraulics, was used with some modifications for an application to unstructured non-staggered grids. This paper is concerned with the effects of interpolation schemes on the simulation of two-phase flows. In order to stabilize a numerical solution and assure a high numerical accuracy, the second-order upwind scheme is implemented into the CUPID code in the present paper. Some numerical tests have been performed with the implemented scheme and the comparison results between the second-order and first-order upwind schemes are introduced in the present paper. The comparison results among the two interpolation schemes and either the exact solutions or the mesh convergence studies showed the reduced numerical diffusion with the second order scheme.

• Journal of The Korean Society of Agricultural Engineers
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• v.51 no.5
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• pp.1-8
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• 2009

Photobioreactor (PBR) that houses and cultivates microalgae providing a suitable environment for its growth, such as light, nutrients, CO2, heat, etc. is now getting more popular in the last decade. Among the many types of PBRs, the bubble column type is very attractive because of its simple construction and easy operation. However, despite the availability of these PBRs, only a few of them can be practically used for mass production. Many limitations still holdback their use especially during their scale-up. To enlarge the culture volume and productivity while supplying optimum environmental conditions, various PBR structures and process control are needed to be investigated. In this study, computational fluid dynamics (CFD) was economically used to design a bubble-column type PBR taking the place of field experiments. CFD is a promising technique which can simulate the growth and production of microalgae in the PBR. To study bubble column PBR with CFD, the most important factor is the possibility of realizing bubble. In this study, multi-phase models which are generally used to realize bubbles were compared by theoretical approaches and comparing in a 2D simulation. As a result, the VOF (volume of fluid) model was found to be the most effective model to realize the bubbles shape as well as the flow inside PBR which may be induced by bubble injection. Considering the accuracy and economical efficiency, 0.005 second time step size was chosen for 2.5 mm mesh size. These results will be used as criteria for scale-up in the PBR simulation.

• The KSFM Journal of Fluid Machinery
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• v.10 no.2 s.41
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• pp.41-45
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• 2007

The shutoff unit was designed to provide rapid insertion of neutron absorbing material into the reactor core to shutdown the reactor quickly and also to withdraw the absorber slowly to avoid a log-rate trip. Four shutoff units were installed on the HANARO reactor but the half-core test facility was equipped with one shutoff unit. The reactor trip or shutdown is accomplished by four shutoff units by insertion of the shutoff rods. The shutoff rod(SOR) is actuated by a directly linked hydraulic cylinder on the reactor chimney, which is pressurized by a hydraulic pump. The rod is released to drop by gravity, when triplicate solenoid valves are de-energized to vent the cylinder. The hydraulic pump, pipe and air supply system are provided to be similar with the HANARO reactor. The shutoff rod drops for 647mm stroke within 1.13 seconds to shut down the reactor and it is slowly inserted to the full down position, 700mm, with a damping. We have conducted the drop test of the shutoff rod in order to show the performance and the structural integrity of operating system of the shutoff unit. The present paper deals with the 647mm drop time and the withdrawal time according to variation of the pool water temperature, the water level and the core flow.

• KSBB Journal
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• v.16 no.1
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• pp.66-70
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• 2001

Factors affecting the supercritical carbon dioxide extraction of camptothecin(CPT) and 10-hydroxycamptothecin(HCPT) from the dried powder of Cmptotheca acuminata were studied. Only a few amount of CPT and HCPT was extracted with pure supercritical carbon dioxide. Methanol and ethanol were efficient modifiers to extract CPT and HCPT. At $40^{\circ}C$, 250 bar, 1 mL/min flow rate, 41% of CPT and 35% of HCPT were extracted with supercritical carbon dioxide modified with 16% of methanol. The diffusion effect of HCPT on extraction efficiency was studied in this solid-fluid system. Round matrix hot-ball model assumption revealed that the value of D/$r^2$ was 0.0072 $min^{-1}$ which was higher than that of solvent extraction with methanol.

• Journal of Korean Society of Environmental Engineers
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• v.29 no.1
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• pp.47-53
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• 2007

The aim of this study is to research applicable possibility or Dry Sorbent Injection Technique(DSI) in sox removal process using Computational Fluid Dynamics(CFD) software package. It will be applied for 500MW in capacity coal-fired thermal power plant operated by South Korea N. Power Co., Ltd. The DSI process is adapted between a preheater and an EP process in the technological assembly. The numerical analysis performs in predicting and optimizing of DSI process's characteristics, which consists of structure of duct, position of injection nozzles, injection speed, and dispersion of sorbent. Computing results are shown that degree of sorbent dispersion depends on structure of duct and position of injection nozzles strongly. The highest dispersion efficiency was obtained when we set a Lobed-plate inside the duct and 6 injection nozzles on the duct(4 injection nozzles at the corners and 2 injection nozzles on upper and under walls as a rectangle duct shape). We also know that change of injection speed of sorbent doesn't have an large effect on the sorbent dispersion but it can effect to drop pressure.

• Water for future
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• v.26 no.1
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• pp.63-69
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• 1993

Remediation technology becomes an issue in environmental engineering. The vibro-recovery technique is one of popular means to remove pollutants from contaminated soils and groundwater. Using Ultrasonic excitation in soil-fluid medium, it was found that removal efficiency in a mechanical effects was significant. In this paper, therefore, laboratory experiments were conducted on clayey sand soil columns using a probe-type ultrasonic processor. Ultrasonic treatment with simultaneous pumping enhances dislodgement of clay particles, and ultrasonic excitation reduced the proportions of finer particles and thus result in increased hydraulic conductivity significantly. Also, the results provided the changes in grain size distribution curve of the soil due to ultrasonic excitation. The results indicated that the maximum size of particles mobilized by Ultrasonic is about 0.004mm and particles in the size range from 0.04mm to 1.0mm were subjected to fracturing. The economic feasibility of Ultrasonic implementation is considered in power requirement of the generator and maintenance of the horn. At a specified amplitude of vibrations, the power requirement of the generator depends on overburden pressure of the horn, temperature and viscosity of fluid in the soil medium. For comparisons, the requirement of a one inch and two inch diameter horn sonicators are compared with the power required for pumping water from different depths.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.36 no.5
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• pp.831-838
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• 2016

The disaster preventing system using vegetation has been growing in the field of coastal engineering in recent years. To analyze wave and flow fields under nonlinear interactions between tsunami and vegetation, the purpose of this study is to evaluate newly-developed 3-D numerical wave tank including energy dissipation by tsunami-vegetation interaction based on existing N-S solver with porous body model. Comparing numerical results using mean drag coefficient and dynamic drag coefficient due to Reynolds number to existing experimental results it is revealed that computed results considering the dynamic drag coefficient are in good agreement with the laboratory test results for time-domain waveform. In addition, the calculated transmission coefficients of solitary waves in various vegetation densities and incident wave heights are also in good agreement with the experimental values. This confirms the validity and effectiveness of the developed 3-D numerical wave tank with the fluid resistance by vegetation.

• The KSFM Journal of Fluid Machinery
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• v.5 no.1 s.14
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• pp.49-54
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• 2002

HANARO, 30 MW of research reactor, was installed at the depth of 13m in an open pool. The $90\%$ of primary coolant was designed to pass through the core and to remove the reaction heat of the cote. The rest, $10\%$, of the primary coolant was designed to bypass the core. And the reactor coolant through and bypass the core was inhaled at the top of chimney by the coolant pump to prevent the radiated gas from being lifted to the top of reactor pool. But, the part of core bypass coolant was not inhaled by the reactor coolant pump and reached at the top of reactor pool by natural convection, and increased the radiation lovel on the top of reactor pool. To reduce the radiation level by protecting the natural convection of the core bypass flow, the hot water layer (HWL, hereinafter) was installed with the depth of 1.2 m from the top of reactor pool. As the HWL was normally operated, the radiation level was reduced to five percent ($5\%$) in comparing with that before the installation of the HWL. When HANARO was operated at a higher temperature than the normal temperature of the HWL by operating the standby heater, it was found that the radiation level was more reduced than that before operation. To verify the reason, the heat loss of the HWL was calculated by Visual Basic Program. It was confirmed through the results that the larger the temperature difference between the HWL and reactor hall was, the more the evaporation loss increased. And it was verified that the radiation level above was reduced mote safely by increasing the capacity of heater.