• Title/Summary/Keyword: flow phantom

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Development of Dynamic Kidney Phantom System and its Evaluation of Usability of Application in Nuclear Medicine (핵의학 동적 신장팬텀시스템 개발 적용의 유용성 평가)

  • Park, Hoon-Hee;Lee, Juyoung;Kim, Sang-Wook;Lyu, Kwang Yeul;Jin, Gye Hwan
    • Journal of radiological science and technology
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    • v.36 no.1
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    • pp.49-55
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    • 2013
  • Currently, commercially available phantom can reproduce and evaluate only a static situation, the study is incomplete research on phantom and system which is can confirmed functional situation in the kidney by time through dynamic phantom and blood flow velocity, various difference according to the amount of radioactive. Therefore, through this study, it has produced the dynamic kidney phantom to reproduce images through the dynamic flow of the kidney, it desires to evaluate the usefulness of nuclear medicine imaging. The production of the kidney phantom was fabricated based on the normal adult kidney, in order to reproduce the dynamic situation based on the fabricated kidney phantom, in this study, it was applied the volume pump that can adjust the speed of blood flow, so it can be integrated continuously radioactive isotopes in the kidney by using $^{99m}Tc$-pertechnate. Used the radioactive isotope was supplied through the two pump. It was confirmed the changes according to the infusion rate, radioactive isotopes and the different injection speeds on the left and right, analysis of the acquired images was done by drawn five times ROI in order to check the reproducibility of each on the front and rear of the kidney and bladder. Depending on the speed of injection, radioisotope was a lot of integrated and emissions up when adjusting the pressure of the pump as 30 stroke, it was the least integrated and emissions up when adjusting as 40 stroke. The integration of the left & right kidney was not reached in the amount of the highest when adjusting as 10 stroke. In the changes according to the amount of the radioactive isotope, 0.6 mCi(22.2 MBq), 0.8 mCi (29.6 MBq)was showed up similar tendency but, in the result of the different injection 0.8 mCi, it was showed up counts close to double of 0.6 mCi. In the result of the differently injection speed of the left & right kidney, as a result of different conditions that injection speed was 20 stroke through left kidney phantom, the injection speed was 30 stroke through right kidney phantom, it was enough difference in the resulting image can be easily distinguished with the naked eye. Through this study, the results showed that the dynamic kidney phantom system is able to similarly reproduce renogram in the actual clinical practice. Especially, the depicted over time for the flow to be excreted through the kidney into the bladder was adequately reproduce, it is expected to be utilized as basic data to check the quality of the dynamic images. In addition, it is considered to help in the field of functional imaging and quality control.

Comparison for Glomerular Filtration Rate in Gamma Camera Systems Using Dynamic Renal Phantom System (동적신장팬텀시스템 개발에 따른 장비별 사구체여과율의 비교)

  • Kang, Chun Goo;Park, Hoon-Hee;Oh, Shin Hyun;Lee, Han Wool;Kim, Jung Yul;Oh, Joo Yung;Lee, Ju Young;Kim, Jae Sam;Lee, Chang Ho
    • The Korean Journal of Nuclear Medicine Technology
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    • v.17 no.2
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    • pp.3-9
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    • 2013
  • Purpose: Currently commercially available phantom can reproduce and evaluate only a static situation, the study is incomplete research on phantom and system which is can confirmed functional situation in the kidney by time through dynamic phantom and blood flow velocity, various difference according to the amount of radioactive. Therefore, through this study, it has produced the dynamic kidney phantom to reproduce images through the dynamic flow of the kidney, it desire to evaluate the usefulness of nuclear medicine imaging. Materials and Methods: The production of the kidney phantom was fabricated based on the normal adult kidney, in order to reproduce the dynamic situation based on the fabricated kidney phantom, in this study it was applied the volume pump that can adjust the speed of blood flow, so it can be integrated continuously radioactive isotopes in the kidney by using $^{99m}Tc-pertechnate$. Used the radioactive isotope was supplied through the two pump. It was confirmed the changes according to the infusion rate, radioactive isotopes and the different injection speeds on the left and right, analysis of the acquired images was done by drawn ten times ROI in order to check the reproducibility of each on the front and rear of the kidney and bladder. Results: Under the same conditions infusion rate 40 mL/min fixed to adjust the pressure of the pump when the radiopharmaceuticals between 2-3 minutes in the most integrated in the kidney phantom was excreted inthe bladder. Glomerular filtration rate (GFR), respectively, by each device SYMBIA 1,091 mL/min, FORTE 1,232 mL/min, ARGUS 1,264 mL/min, INFINIA 1,302 mL/min in that there isno statistically significant difference was found, Tmax values and T1/2 values stars from all equipment with no statistically significant difference was found. CV values of the coefficient of variation less than 5% was found to be repeatable, and to 2.67% of the lowest SYMBIA appeared, INFINIA was the highest in the 4.86%. Conclusion: Through this study, the results showed that the dynamic kidney phantom system is able to similarly reproduce renogram in the actual clinical. Especially, the depicted over time for the flow to be excreted through the kidney into the bladder was adequately reproduce, it is expected to be utilized as basic data to check the quality of the dynamic images. In addition, it is considered to help in the field of functional imaging and quality control.

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A Study of Signal Intensity of MRA in Flow Phantom of Fusiform Aneurysm (방추형 동맥류 모형에서 자기공명 혈관조영술의 신호강도에 대한 연구)

  • 한기석
    • Investigative Magnetic Resonance Imaging
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    • v.2 no.1
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    • pp.83-88
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    • 1998
  • Purpose : Authors correlated the three-dimensional time-of-flight MRA signal intensity characteristics and flow profile simulated by computer in an experimental flow phantom model. Materials and Methods : The three-dimensional time-of-flight MRA was performed in a fusiform flow phantom and analyzed the flow signal. computer assisted flow simulation was performed in same flow geometry. The MRA signal intensity and flow velocity distribution and direction was compared. Results : The flow was depicted as homogeneous signal internsity in inlet and outlet area and inhomogeneous signal intensity in fusiform area. Typically, the flow was depicted as target appearance in transition area to outlet. Whereas mean signal internsity decreased slowly in fusiform area, it rapidly dropped and resumed in transition area to outlet. In computer assisted flow simulation, Whereas there were flow velocity decrease and flow direction change to peripheral in entrance to fusiform area, ther were rapid flow velocity resuming and flow direction change to central in transition area to outlet. Conclusion : The signal loss and target appearance in transition area to outlet is characteristic of fusiform flow. These signal changes correlate with abrupt flow velocity and direction change well.

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Center-of-Gravity Effect on Supersonic Separation from the Mother Plane (무게중심 변화에 따른 초음속 공중발사 로켓의 모선분리 연구)

  • Ji Young-Moo;Lee Jae-Woo;Byun Yung-Hwan;Park Jun-Sang
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2006.05a
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    • pp.36-40
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    • 2006
  • An analysis is made of flow and rocket motion during a supersonic separation stage of air-launching rocket(ALR) from the mother plane. Three-dimensional compressible Navier-Stokes equations is numerically solved to analyze the steady/unsteady flow field around the rocket which is being separated from the mother plane configuration(F-4E Phantom). The simulation results clearly demonstrate the effect of shock-expansion wave interaction between the rocket and the mother plane. To predict the behavior of the ALR according to the change of the C.G., three cases of numerical analysis are performed. As a result, a design-guideline of supersonic air-launching rocket for the safe separation is proposed.

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Tomographic Reconstruction of Two-Phase Flows

  • Ko, Han-Seo;Kim, Yong-Jae
    • Journal of Mechanical Science and Technology
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    • v.17 no.4
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    • pp.571-580
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    • 2003
  • Tomography has been investigated to observe bubble behaviors in two-phase flows. A bubbly flow and an annular flow have been reconstructed by tomography methods such as an algebraic reconstruction technique (ART) and a multiplicative algebraic reconstruction technique (MART) . Computer synthesized phantom fields have been used to calculate asymmetric density distributions for limited cases of 3, 5, and 7 projection angles. As a result of comparison of two tomography methods, the MART method has shown a significant improvement in the reconstruction accuracy for analysis of the two-phase flows.

Center-of-Gravity Effect on Supersonic Separation from the Mother Plane (무게중심 변화에 따른 초음속 공중발사 로켓의 모선분리 연구)

  • Ji, Young-Moo;Lee, Jae-Woo;Byun, Yung-Hwan;Park, Jung-Sang
    • 유체기계공업학회:학술대회논문집
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    • 2006.08a
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    • pp.423-426
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    • 2006
  • An analysis is made of flow and rocket motion during a supersonic separation stage of air-launching rocket(ALR) from the mother plane. Three-dimensional compressible Navier-Stokes equations is numerically solved to analyze the steady/unsteady flow field around the rocket which is being separated from the mother plane configuration(F-4E Phantom). The simulation results clearly demonstrate the effect of shock-expansion wave interaction between the rocket and the mother plane. To predict the behavior of the ALR according to the change of the C.G., three cases of numerical analysis are performed. As a result, a design-guideline of supersonic air-launching rocket for the safe separation is proposed.

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Effects of Flow Rates and CS Factors on TOF MRA using Compressed Sensing (Compressed sensing을 이용한 TOF MRA 검사에서 Flow rate와 CS factor의 변화에 따른 영향)

  • Kim, Seong-Ho;Jeong, Hyun-Keun;Yoo, Se-Jong
    • Journal of the Korean Society of Radiology
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    • v.15 no.3
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    • pp.281-291
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    • 2021
  • This study aimed to measure the quantitative changes in images according to the use of compressed sensing in expressing the slow flow rate in TOF MRA test using magnetic resonance imaging. This study set different blood flow rate sections by using auto-injector and flow phantom and compared changes in the SNR, CNR, SSIM, and RMSE measurements by different CS factors between TOF with CS and TOF without CS. One-way ANOVA was performed to test the effect on the image induced by the increase of the CS factor. The results revealed that TOF MRA with CS significantly decreased scan time without significantly affecting SNR and CNR compared to TOF MRA with CS. On the other hand, the differences in SSIM and RMSE between TOF with CS and TOF without CS increased as the CS factor increased. Therefore, it is necessary to efficiently reduce scan time by adapting the CS technique while considering the appropriate range of the CS factor. Additionally, more studies are needed to evaluate CS factors and the similarity precision of images further.

Scan Time Analysis Using 4D Phase-Contrast MRI According to Scan Parameter: A Phantom Study (스캔 인자에 따른 4D 위상 대조 자기공명영상을 이용한 스캔 시간 분석: 팬텀 연구)

  • Park, Jieun;Kim, Junghun;Hwang, Moonjung;Lee, Jongmin
    • Journal of Biomedical Engineering Research
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    • v.41 no.5
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    • pp.179-184
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    • 2020
  • Purpose: The purpose of this study was to evaluate the effect according to the NEX, VENC, targeted cardiac phases on the velocity measurement of 4D phase-contrast MRI. Materials and Methods: The abdominal aortic phantom was made to experiment. The working fluid was mixed with water and glycerin to mimic the density and viscosity of human blood. The inlet velocity was Reynolds number 2000. The experimental conditions were NEX 1 and 4, VENC 102 cm/s and 200 cm/s, and 10 and 15 targeted cardiac phases, respectively. The average flow rate, average velocity, maximum velocity, and cross-section area were measured. Results: As a result of the case-by-case comparison, the error rate was less than 5%. There was no significant difference (p > 0.05). Conclusion: It is expected that this result will be useful for acquiring blood flow information in clinical practice.

Flow Effects on Tailored RF Gradient Echo (TRFGE) Magnetic Resonance Imaging : In-flow and In-Plane Flow Effect (Tailored RF 경자사계방향 (TRFGE} 자기공명영상(MRI)에서 유체에 의한 영상신호 변화 : 유체유입효과와 영상면내를 흐르는 유체의 효과에 대하여)

  • Mun, Chi-Ung;Kim, Sang-Tae;No, Yong-Man;Im, Tae-Hwan;Jo, Jang-Hui
    • Journal of Biomedical Engineering Research
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    • v.18 no.3
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    • pp.243-251
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    • 1997
  • In this paper, we have reported two interesting flow effects arising in the TRFGE sequence using water flow phantom. First, we have shown that the TRFGE sequence is indeed not affected by "in-flow" effect from the unsaturated spins flowing into the imaging slice. Second, the enhancement of "in-plane flow" signal in the readout gradient direction was observed when the TRFGE sequence was used without flow compensation. These two results have many interesting applications in MR imaging other than fMRI. Results obtained were also compared with the results obtained by the conventional gradient echo(CGE) imaging. Experiments were performed at 4.7T MRI/S animal system (Biospec, BRUKER, Switzerland). A cylindrical phantom was made using acryl and a vinyl tube was inserted at the center(Fig. 1). The whole cylinder was filled with water doped with $MnCl_2$ and the center tube was filled with saline which flows in parallel to the main magnetic field along the tube. Tailored RF pulse was designed to have quadratic ($z^2$) phase distribution in slice direction(z). Imaging parameters were TR/TE = 55~85/10msec, flip angle = $30^{\circ}$, slice thickness = 2mm, matrix size = 256${\times}$256, and FOV= 10cm. In-flow effect : Axial images were obtained with and without flow using the CGE and TRFGE sequences, respectively. The flow direction was perpendicular to the image slice. In-plane flow : Sagittal images were obtained with and without flow using the TRGE sequence. The readout gradient was applied in parallel to the flow direction. We have observed that the "in-flow" effect did not affect the TRFGE image, while "in-plane flow" running along the readout gradient direction enhanced the signal in the TRFGE sequence when flow compensation gradient scheme was not used.

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An Experimental Study on the Cause of Signal Inhomogeneity for Magnetic Resonance Angiography Using Phantom Model of Anterior Communicating(A-com) Artery (전교통동맥 모형을 이용한 자기공명혈관촬영술의 신호 불균일에 관한 실험적 연구)

  • Yoo, Beong-Gyu;Chung, Tae-Sub
    • Journal of radiological science and technology
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    • v.25 no.1
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    • pp.55-62
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    • 2002
  • Aneurysm-mimicking findings were frequently visualized due to hemodynamical causes of dephasing effects around area of A-com artery during magnetic resonance angiography(MRA) and these kind of phenomena have not been clearly known yet. We investigated the hemodynamical patterns of dephasing effect around area of the A-com artery that might be a cause of false intracranial aneurysms on MRA. For experimental study, We used hand-made silicon phantoms of the asymmetric A-com artery as like a bifurcation configuration. In a closed circulatory system with UHDC computer driven cardiac pump system. MRA and fast digital subfraction angiography(DSA) involved the use of these phantoms. Flow patterns were evaluated with axial and coronal imaging of MRA(2D-TOF, 3D-TOF) and DSA of Phantoms constructed from an automated closed-type circulatory system filled with glycerol solution [circulation fluid(glycerol:water = 1:1.4)]. These findings were then compared with those obtained from computational fluid dynamic(CFD) for inter-experimental correlation study. Imaging findings of MRA, DSA and CFD on inflow zone according to the following: a) MRA demonstrated high signal intensity zone as inflow zone on silicon phantom; b) Patterns of DSA were well matched with MRA on trajectory of inflow zone; and c) CFD were well matched with MRA on the pattern of main flow. Imaging findings of MRA. DSA and CFD on turbulent flow zone according to the following: a) MRA demonstrated hyposignal intensity zone at shoulder and axillar zone of main inflow; b) DSA delineated prominent vortex flow at the same area. The hemodynamical causes of signal defect, which could Induce the false aneurysm on MRA, turned out to be dephasing effects at axilla area of bifurcation from turbulent flow as the results of MRA, DSA and CFD.

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