• Journal of Korean Society on Water Environment
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• v.22 no.3
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• pp.475-481
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• 2006

The major problem in closing water like lakes and ponds in Korea is that because they are exposed to surrounding, so easily polluted. The pollution in closing water can be caused by not only artificial factor like sewage but also natural factor like elution from sediment. For insurance of safe and satisfied water source, lots of studies and projects are now going on. In this study, we examined the behavior and effect of microbubble ($3{\sim}10{\mu}m$) produced by device called O.S.D (Oxygen Solubillization Device) in small size pond. The value of oxygen transfer coefficient ($K_La$) was 0.68/min independently of air flow rate, 6.5 times higher than commercial aeration stone and the variation of nitrogen concentration was $0.008NO_3/O_2$, DO concentration was potentially saturated for 24 hr. From the results of pilot plant, SOD of experiment (O.S.D) and control were $12.18gO_2{\cdot}m^{-2}{\cdot}d^{-1}$ and $47.95gO_2{\cdot}m^{-2}{\cdot}d^{-1}$ respectively. In conclusion, because O.S.D has extraordinary physico-chemical characteristics, it can contribute to improvement of both the waterbody and the sediment environment.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.4
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• pp.879-892
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• 2003

This thesis makes a review of symptoms and cause of the numbness in the literature. clinical case are studied and classified according to the Hyungsang of the patients. The followings are the conclusions: In case of Dam type persons, numbness is mainly caused by Fire with blood deficiency and so cured by tonifying the Jung and blood. In case of Bang Kwang type persons. it is generally caused by the deficiency of Ki and damp-phlegm and treated by reinforcing Ki and removing dampness. Persons of Jung and Hyal types are apt to be afflicted with numbness of deficiency symptoms which can be cured by tonifying the Jung and blood. Those of Ki and Shin types are inclined to get numb from the congestion and stagnancy and so treated by promotion the flow of Ki, dispelling stagnancy, resolving phlegm and promoting digestion. Numbness is common to the old people and women. The deficiency of blood and primordial energy is a cause of old people's numbness. Women get numb due to the pent-up feelings and emotional disturbance. The function disharmony of five Jang and six Bu makes the body lose the control of heat and cold or deficiency and excessiveness, which can be a cause of numbness. Especially the deficiency of the spleen results in numbness. When the special parts of the body become numb treatment must be decided after due consideration on which of the Jang and Bu or meridians is related to that affected area. In case of person with six meridian types. unbalance of Ki and blood leads the six atmospheric influences(wind, cold, heat, dampness, dryness and fire) get into the body through the most developed meridian and brings in numbness.

• Molecules and Cells
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• v.40 no.5
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• pp.363-370
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• 2017

Extrahepatic cholangiocarcinoma (ECC), a malignant tumor of biliary origin, has a poor prognosis with limited treatment options. The KRAS oncogene is the most commonly mutated gene in ECC and one of the factors that predicts a poor prognosis and low survival rate. L1 cell adhesion molecule (L1CAM) is expressed in ECC cells and acts as an independent poor prognostic factor in predicting patient survival. In this study we investigate the functional significance of L1CAM in ECC cells with activating KRAS mutation. We selected an ECC cell line, EGI-1, with activating KRAS mutation, and then confirmed its expression of L1CAM by RT-PCR, western blot analysis, and flow cytometry. The suppression of L1CAM expression (using a specific lentivirus-delivered shRNA) significantly decreased the migratory and invasive properties of EGI-1 cells, without altering their proliferation or survival. Analyses of signaling effectors in L1CAM-depleted and control EGI-1 cells indicated that L1CAM suppression decreased the levels of both phosphorylated MKK4 and total MKK4, together with c-Jun N-terminal kinase (JNK) phosphorylation. Further, exposure to a JNK inhibitor (SP600125) decreased migration and invasion of EGI-1 cells. These results suggest that L1CAM promotes cellular migration and invasion via the induction of MKK4 expression, leading to JNK activation. Our study is the first to demonstrate a functional role for L1CAM in ECC carrying the activating KRAS mutation. Given that KRAS is the most commonly mutated oncogene in ECC, L1CAM may serve as an attractive therapeutic target for ECC cells with activating KRAS mutation.

• Applied Chemistry for Engineering
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• v.23 no.6
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• pp.608-613
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• 2012

Dielectric barrier discharge plasma reactor was applied to the removal of ethylene from a simulated storage facility ($1.0m^3$) of fruits and vegetables. The system operated in a closed-loop mode by feeding the contaminated gas to the plasma reactor and recirculating the treated gas back to the storage facility. The experiments were carried out with parameters such as discharge power, circulation flow rate, initial ethylene concentration and treatment time. The rate of ethylene decomposition was mainly controlled by the discharge power and the treatment time. With the other conditions kept constant, the ethylene decomposition rate in the presence of the manganese oxide ozone control catalyst installed downstream from the plasma reactor was lower than that in the absence of it. The suggests that unreacted ozone from the plasma reactor accumulated in the storage facility where it additionally decomposed ethylene. On the basis of an initial ethylene concentration of 50 ppm, the energy requirement for completing the decomposition was about 60 kJ.

• Journal of fish pathology
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• v.17 no.1
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• pp.67-74
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• 2004

This study investigates the influence of waterborne ammonia and nitrite on the zoea and megalopa stage larvae of tiger crab, Orithyia sinica under laboratory condition, focusing on the effects on survival and growth as deleterious responses of toxicant. Survival rate of zoea stage larvae exposed to control levels, and to 5, 10, 20 and 50 mg/L total ammonia-N, using a continuous flow system for 20 days was 80, 77, 45, 40 and 37%, respectively. Growth rate of zoea stage larvae exposed to 20 and 50 mg/L total ammonia was significantly lower than in controls after 20 days (P< 0.05). Survival rate and growth rate of megalopa stage larvae exposed to ammonia also decreased at greater than 10 and 50 mg/L, respectively. In the nitrite exposure experiment with zoea and megalopa stage larvae of tiger crab, survival rate was decreased in a concentration and exposure period-dependent way. The growth rate of zoea and megalopa stage larvae of tiger crab exposed to nitrite decreased at greater than 150 mg/L nitrite concentration.

• Fire Science and Engineering
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• v.18 no.1
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• pp.42-48
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• 2004

The deterministic modeling techniques like Zone model and Field model are mainly used for thermal distribution and smoke flow at fire case in multi use facilities. While Zone model analyse fire simulation by dividing spaces by 2 section, the Field model dividing many cells. However, the difficultly follows to prove efficiency between the two models when it applys. Therefore new modeling development is required which in closes to real situation by verify number algorithm and related data for fire modeling. The paper analyses the efficiency of two different fire modeling at interior spaces of multiplex cinema theater. It is found that the zone model for average distribution and the field model for detail space phenomenon are relevant to apply. Also, Filed model is useful to the result that fire analysis and position of detector and review for smoke control system.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.11
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• pp.4529-4536
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• 2010

This paper develops an interconnection test devices for photovoltaic(PV) systems composed of distribution system simulator, PV systems simulator and control and monitoring systems using the LabVIEW S/W, and simulates the customer voltage characteristics considering the 3 parameters on the introduction capacity for PV systems, system configuration and load factor. This paper also proposes a new calculation algorithm for voltage profile to make a comparison between calculation values and test device values. The results show that the test results for the normal operation characteristics of PV systems is very practical and effective.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.5
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• pp.3270-3278
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• 2014

Many researches has been conducted as extreme rainfall in hydrology and extreme rainfall analysis is not proper for determination of CSOs treatment capacity. In this study, runoff is calculated by tranformation from rainfall to runoff according to Interevent Time Definition. The capacity of sewage treatment plant is designed by 3 times of DWF(Dry Weather Flow) and the efficiency of present sewage treatment plant is very low becauseat at present. Also, The sewage treatment plant can not control CSOs. In this research, the pollution load is calculated by EMC(Event Mean Concentration) and pollution concetration of total runoff is a standard deciding suitablility of present sewage treatment plant. Finally, CSOs treatment capacity is determinated considering pollution load.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.25 no.3
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• pp.197-204
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• 1992

A comparative evaluation of water quality in the existing semiclosed fish culture system was made to improve the system management. From the comparison of water quality between the flow-through mode and the recycle mode of the semiclosed system, the malfunctioning of the settling channel deteriorated water quality and reduce the nitrification rate in the recycle mode. The peak concentrations of COD, $PO_4-P$ and SS in the fish tanks appeared just after feeding, and then decreased to normal levels within two hours. However, the $NH_4-N$ concentration increased slightly after two hours of feeding in the recycle mode. The water exchange rate was directly related to the water quality in the semiclosed fish culture system.

• Journal of Korean Clinical Nursing Research
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• v.25 no.3
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• pp.251-264
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• 2019

Purpose: This study was a systematic review and meta-analysis to explore the factors related to quality of life in heart transplant recipients. Methods: To identify studies that suggested the factors related to the quality of life in heart transplant recipients, we searched the articles published from 1974 to November 2018 using Six databases, PubMed, CINAHL, EMBASE, Cochrane, KMBASE and RISS. A total of 22 studies were selected out of 5,234 for the systematic review and meta-analysis on the basis of the PRISMA flow. The quality of study was assessed by assessment tool form the NIH and meta-analysis was performed using the 'R 3.5.2' version to analyze the correlated effect sizes. Results: Factors related to quality of life in heart transplant recipients were categorized into six domains based on the health-related quality of life model introduced by Ferrans: individual, environmental, biological function, symptoms, functional status, and general health perception. In the meta-analysis, 34 factors were used and 17 factors having significant effect sizes were as follows: self-efficacy, demoralization, perceived control, current occupational status, age, marital status, health promotion life style in the individual characteristics; stress in environmental characteristics; physical function status, creatinine level, left ventricular ejection fraction (LVEF) in biological function; anxiety, depression, symptom frequency and distress in symptoms domain; coping, self-care compliance in functional status. Conclusion: The findings indicate that the multi-dimensional factors influencing the quality of life in heart transplant recipients and provide the evidence for developing effective interventions for improving the quality of life of recipients.