• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.2D
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• pp.185-192
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• 2011

More practical outputs and insights can be obtained through transportation analysis considering the time-dependent traffic movements. This study proposes a method of constructing time-dependent O-D trip tables for expressway corridor using real-world individual trip data. In this study, time-dependent O-D trip tables for the nationwide highway network are constructed based on toll collection system data. The proposed methodology is to convert nationwide time-dependent O-D trip tables into Korean expressway corridor O-D trip tables in order to deal with the computational complexity arising from simulating a large-scale traffic network. The experiment results suggest that actual individual trip record data can be used to effectively construct time-dependent O-D trip tables. They also imply that the construction of time-dependent O-D trip tables for the national highway networks along with those for Korean expressway developed in this study would make transportation analysis more practical and applicable to real-time traffic operation and control.

• Journal of the Korean Society of Propulsion Engineers
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• v.21 no.3
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• pp.1-9
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• 2017

Numerical computations are performed to investigate the effect of pintle stroke on the performance of an internal pintle thruster. Results show that the thrust control ratio was less than 2% and the aerodynamic load ratio was 22% as the pintle stroke increased. The flow past the nozzle throat rapidly expanding because of the shape of the pintle, and a shock wave was generated. Particularly, at the pintle stroke distance of 4 and 5 mm, the shock wave hit the wall of the nozzle, results in peeling bubbles. Depending on the altitude, the thrust increased and the aerodynamic load decreased, but the difference was as small as 1.5%. In the presence of the bore, the reduction of the pintle tip area resulted in a decrease in aerodynamic load.

• Journal of Advanced Marine Engineering and Technology
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• v.40 no.10
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• pp.906-915
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• 2016

In this study, a network monitoring system, including a secure 460-Network and a 460-Gateway, is designed and developed according with the requirements of the IEC (International Electro-Technical Commission) 61162-460 network standard for the safety and security of networks on board ships. At present, internal or external unauthorized access to or malicious attack on a ship's on board systems are possible threats to the safe operation of a ship's network. To secure the ship's network, a 460-Network was designed and implemented by using a 460-Switch, 460-Nodes, and a 460-Gateway that contains firewalls and a DMZ (Demilitarized Zone) with various application servers. In addition, a 460-firewall was used to block all traffic from unauthorized networks. 460-NMS (Network Monitoring System) is a network-monitoring software application that was developed by using an simple network management protocol (SNMP) SharpNet library with the .Net 4.5 framework and a backhand SQLite database management system, which is used to manage network information. 460-NMS receives network information from a 460-Switch by utilizing SNMP, SNMP Trap, and Syslog. 460-NMS monitors the 460-Network load, traffic flow, current network status, network failure, and unknown devices connected to the network. It notifies the network administrator via alarms, notifications, or warnings in case any network problem occurs. Once developed, 460-NMS was tested both in a laboratory environment and for a real ship network that had been installed by the manufacturer and was confirmed to comply with the IEC 61162-460 requirements. Network safety and security issues onboard ships could be solved by designing a secure 460-Network along with a 460-Gateway and by constantly monitoring the 460-Network according to the requirements of the IEC 61162-460 network standard.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.10
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• pp.1105-1110
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• 2011

Flow-accelerated corrosion (FAC) is a well-known phenomenon that may occur in piping and components. Most nuclear power plants have carbon-steel-pipe wall-thinning management programs in place to control FAC. However, various other erosion mechanisms may also occur in carbon-steel piping. The most common forms of erosion encountered (cavitation, flashing, Liquid Droplet Impingement Erosion (LDIE), and Solid Particle Erosion (SPE)), have caused wall thinning, leaks, and ruptures, and have resulted in unplanned shutdowns in utilities. In particular, the damage caused by LDIE is difficult to predict, and there has been no effort to protect piping from erosive damage. This paper presents an evaluation method for LDIE. It also includes the calculation results from prediction models, a review of the experimental results, and a comparison between the UT data in the damaged components and the results of the calculations and experiments.

• Proceedings of the SAREK Conference
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• 2008.11a
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• pp.21-26
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• 2008

Recently, small and medium-sized buildings have employed a multi-heat pump. The major benefits of the multi-heat pump over a conventional system are that it is easier system to maintain along with a diversification of facility use, and high comfortability. The performance of multi-heat pump systems can be enhanced by using geothermal energy instead of air source energy. This paper describes the multi-heat pumps applied in an ground source heat pump system for an actual building. The performance of a ground source multi-heat pump installed in the field was investigated in cooling mode. The maximum COP of the systems with single U-tube and double tube ground loop heat exchangers were 6.6 and 6.0, respectively. It is suggested that the new algorithms to control the flow rate of secondary fluid for ground loop heat exchanger have to be developed in order to enhance the performance of the system.

• Journal of Ginseng Research
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• v.22 no.1
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• pp.22-31
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• 1998

Antiulcer effects of ginseng saponin, acidic polysaccharide and methanol extract of Panax ginseng in the patients and experimental animals were reported. Postulated action mechanisms of ginseng were histamine-Ht receptor blocking and increasing gastric blood flow In the present study, the effect of ginsenosides, the biologically active glycosides of ginseng, on gastric acid secretion was examined using gastric cells isolated from human and rabbit gastric mucosa. Ginseng saponin, ginsenoside $Rb_1$, $Rb_2$, $Rg_1$ and $Rh_2$ were tested in unstimulated as well as stimulated gastric cells. Histamine ($10^4$M) and 3-isobutyl-1-methylxanthine ($10^4$M) were used as secretagogues. To investigate the mechanism of ginsenosides on acid secretion, the levels of cAMP and cGMP were monitored in gastric cells. As a result, high concerltration(1mg/ml) of ginseng saponin showed 73-75% of stimulated acid secretion in control gastric cells. However, ginseng saponin had no effect on unstimulated acid secretion and the levels of cGMP and cAMP in gastric cells. Ginsenoside $Rb_1$, $Rb_2$ and $Rh_2$ significantly inhibited stimulated acid secretion. Gastric cGMP levels were increased by all ginsenosides tested while cAMP levels were increased by all ginsenosides in unstimulated state of gastric cells, but increased by ginsenosides ginsenoside $Rg_1$ and $Rh_2$in stimulated state of gastric cells. The results suggest that inhibition of ginseng saponin on gastric acid secretion represents a complex effect of individual ginsenosides, which produce a range of effect on acid secretion. The inhibition site of ginseng saponin on stimulated acid secretion is postulated as post cAMP levels in acid secretary pathway such as protein phosphorylation or proton pump. Nitric oxide may not be involved in the inhibitory effect of ginseng saponin on stimulated acid secretion.

• Journal of Ginseng Research
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• v.36 no.1
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• pp.78-85
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• 2012

Endothelial progenitor cells (EPC) are a population of cells that circulate in the blood stream. They play a role in angiogenesis and, therefore, can be prognostic markers of vascular repair. Ginsenoside $Rg_3$ prevents endothelial cell apoptosis through the inhibition of the mitochondrial caspase pathway. It also affects estrogen activity, which reduces EPC senescence. Sun ginseng (SG), which is heat-processed ginseng, has a high content of ginsenosides. The purpose of this study was to investigate the protective effects of SG on senescence-associated apoptosis in EPCs. In order to isolate EPCs, mononuclear cells of human blood buffy coats were cultured and characterized by their uptake of acetylated low-density lipoprotein (acLDL) and their binding of Ulex europaeus agglutinin I (ulex-lectin). Flow cytometry with annexin-V staining was performed in order to assess early and late apoptosis. Senescence was determined by ${\beta}$-galactosidase (${\beta}$-gal) staining. Staining with 4'-6-Diamidino-2-phenylindole verified that most adherent cells (93${\pm}$2.7%) were acLDL-positive and ulex-lectin-positive. The percentage of ${\beta}$-gal-positive EPCs was decreased from 93.8${\pm}$2.0% to 62.5${\pm}$3.6% by SG treatment. A fluorescence-activated cell sorter (FACS) analysis showed that 4.9% of EPCs were late apoptotic in controls. Sun ginseng decreased the apoptotic cell population by 39% in the late stage of apoptosis from control baseline levels. In conclusion, these results show antisenescent and antiapoptotic effects of SG in human-derived EPCs, indicating that SG can enhance EPC-mediated repair mechanisms.

• YAKHAK HOEJI
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• v.56 no.5
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• pp.280-287
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• 2012

A high-performance liquid chromatography (HPLC) combined with ultraviolet (UV) method for the simultaneous determination of ${\alpha}$-cyperone and nootkatone was developed for the quality control of Cyperus rotundus Linne. The separation was performed on a KR100-$5C_{18}$ ($4.6{\times}250mm$) column, and an elution gradient composed of methanol and water with a flow-rate of 1.0 ml/min. Detection wavelength was set at 254 nm. The optimum extraction for the detection of the ${\alpha}$-cyperone and nookatone was achieved by ultrasonic with methanol for an hour. Two marker compounds ${\alpha}$-cyperone and nootkatone in Cyperi Rhizoma showed good linearity ($R^2$ >0.999) in the concentration range of $12.5{\mu}g/ml$ to $200{\mu}g/ml$. The developed method provided satisfactory precision and accuracy with overall intra-day and inter-day variations of 0.04~1.23% and 0.08~0.68%, respectively, and the overall recoveries of 97.45~105.58% for the two compounds analyzed. Additionally, a difference was observed in the cluster analysis and principal component analysis between Cyperi Rhizoma in Korea and China. The result demonstrated that the principal component analysis is useful to distinguish between Cyperi Rhizoma in Korea and China.

• Journal of Sasang Constitutional Medicine
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• v.25 no.1
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• pp.51-61
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• 2013

Objectives We performed the simultaneous analysis for three compounds in Cheongsimyeonja-tang (CSYJT) and evaluated its anti-obesity effect. Methods The column for separation of three compounds was used Gemini $C_{18}$ column and maintained at $40^{\circ}C$. The mobile phase for gradient elution consisted of two solvent systems. The analysis was carried out at a flow rate of 1.0 mL/min with PDA detection at 275 nm. The injection volume was $10{\mu}L$. 3T3-L1 preadipocytes were differentiated into adipocytes by adding insulin, dexamethasone and 3-isobutyl-1-methylxanthine (IBMX) for 8 days in the absence or presence of CSYJT. Anti-obesity effects of CSYJT were evaluated by Oil Red O staining, glycerol-3-phosphate dehydrogenase (GPDH) activity, triglyceride contents, and leptin production. Results Calibration curves were acquired with $r^2$ >0.9999. The contents of baicalin, wogonoside and baicalein in CSYJT were 14.54-14.65 mg/g, 5.24-5.27 mg/g and 0.01-0.02 mg/g, respectively. CSYJT showed inhibitory effect on lipid accumulation and GPDH activity in the differentiated 3T3-L1 cells. Furthermore, CSYJT significantly decreased contents of triglyceride and leptin production in 3T3-L1 adipocytes. Conclusions These results will be helpful to improve quality control and anti-obesity effect of Taeeumin CSYJT.

• Journal of the Korea Society of Computer and Information
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• v.15 no.6
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• pp.49-56
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• 2010

In this paper, a joint PHY-MAC layer optimized resource allocation scheme for OFDMA based micro base stations is investigated. We propose cross-layer optimized two-stage resource allocation scheme including cross-layer functional description and control information flow between PHY-MAC layers. The proposed two-stage resource allocation scheme consists of a user grouping stage and a resource allocation stage. In the user grouping stage, users are divided into a macro base station user group and a micro base station user group based on the PHY-MAC layer characteristics of each user. In the resource allocation stage, a scheduling scheme and an allotment of resources are determined. In the proposed scheme, diversity and adaptive modulation and coding (AMC) schemes are exploited as schedulers. Simulation results demonstrate that the proposed scheme increases the average cell throughput about 40~80 % compared to the conventional system without micro base stations.