• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.7
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• pp.740-748
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• 2016

IT and communication technologies has contributed significantly to the convenience of passengers and the financial management of stations in accordance with the task automation in the field of the urban railway system. The foundation of the above development is based on the large amounts of data from various sensors installed in railways, trains, and stations. In particular, the sensor network that is installed in the station and train has played an important role in the railway information system. The performance of AP is affected by the number of APs and their locations installed in the station. In the installation of APs in stations, the intensity of the radio wave of the AP on its underlying position is considered to determine the number and position of APs. This paper proposes a method to estimate the number of APs and their position based on the structure of the underlying station and implemented a simulator to simulate the performance of the proposed method. The implemented simulator was applied to the decision of AP installation at Busan Seomyeon station to evaluate its performance.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.8
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• pp.4049-4057
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• 2016

Background: High-risk human papillomaviruses (HR-HPV), particularly types 16 and 18, have been found to play an important role in head and neck cancer, including oropharyngeal squamous cell carcinoma (OPSCC) and oral squamous cell carcinoma (OSCC). p16, a cell cycle inhibitor, has been postulated as a surrogate marker for HR-HPV, since p16 is aberrantly overexpressed in such lesions, especially in HR-HPV-positive OPSCC. However, p16 as a surrogate marker for HR-HPV infection in cancers of the oral cavity remains controversial. Objective: The objectives of the study were to investigate the expression of p16 and the presence of HR-HPV in OSCC and oral verrucous carcinoma (VC) and to determine if p16 could be used as a surrogate marker for HR-HPV. Materials and Methods: Forty one formalin-fixed, paraffin-embedded tissues of OSCC (n=37) or VC (n=4) with clinical and histopathologic data of each case were collected. Expression of p16 was determined by immunohistochemistry, focusing on both staining intensity and numbers of positive cells. The presence of HPV types 16 and 18 was detected by polymerase chain reaction (PCR). Descriptive statistics were employed to describe the demographic, clinical, and histopathologic parameters. Associations between p16 overexpression, HR-HPV and all variables were determined by Fisher's exact test, odds ratios (ORs) and corresponding 95% confidence intervals (CIs). In addition, the use of p16 as a surrogate marker for HR-HPV was analyzed by sensitivity and specificity tests. Results: p16 was overexpressed in 8/37 cases (21.6%) of OSCC and 2/4 cases (50%) of VC. HPV-16 was detected in 4/34 OSCC cases (11.8%) and HPV-18 was detected in 1/34 OSCC cases (2.9%). Co-infection of HPV-16/18 was detected in 1/4 VC cases (25%). Both p16 overexpression and HR-HPV were significantly associated with young patients with both OSCC and VC (p<0.05, OR 20, 95% CI 1.9-211.8; p<0.05, OR 23.3, 95% CI 2.4-229.7, respectively). p16 was able to predict the presence of HPV-16/18 in OSCC with 40% sensitivity and 79.3% specificity and in VC with 100% sensitivity and 66.7% specificity, respectively. Conclusions: p16 overexpression was found in 24.4% of both OSCC and VC. HR-HPV, regardless of type, was detected in 15.8% in cases of OSCC and VC combined. The results of sensitivity and specificity tests suggest that p16 can be used as a surrogate marker for HR-HPV in OSCC and VC.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.45 no.7
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• pp.32-36
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• 2008

In this study, $In_2O_3-ZnO$ thin films are prepared on quartz substrates by the pulsed laser deposition and their optical and electrical properties are investigated as the function of substrate temperatures ($200{\sim}600^{\circ}C$) at the fixed oxygen pressure of 200 mTorr. The XRD measurement shows that polycrystalline $In_2O_3-ZnO$ thin films are formed. In the XRD measurement, the intensity of the (400) $In_2O_3$ peak at $35.5^{\circ}$ decreases and that of the (222) $In_2O_3$ peak at $30.6^{\circ}$ increases with the increase substrate temperature up to $500^{\circ}C$. From the result of AFM measurement, the morphology of $In_2O_3-ZnO$ thin films are observed as round-type grains. The lowest surface roughness (6.15 nm) is obtained for the $In_2O_3-ZnO$ thin film fabricated at $500^{\circ}C$. The optical transmittance of $In_2O_3-ZnO$ thin films are higher than 82% in the visible region. The maximum carrier concentration of $2.46{\times}10^{20}cm^{-3}$ and the minimum resistivity of $1.36{\times}10^{-3}{\Omega}cm$ are obtained also for the $In_2O_3-ZnO$ thin film fabricated at $500^{\circ}C$.

• The Journal of Korean Physical Therapy
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• v.15 no.4
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• pp.1-12
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• 2003

The purpose of this study was to investigate the effect of high voltage pulsed current stimulation (HVPCS) on the healing rate of a dermal wound in a rat. We also determined the mechanism of promoting healing by HVPCS. Twenty male Sprague-Dawley rats were randomly divided into two group; HVPCS group (n=10) and control group (n=10). The HVPCS rats received electrical stimulation with a current intensity of 50 V at 100 pps for a duration of 30 minutes, while the control group was given the same treatment without electricity for a week. The biopsy specimens were fixed in formalin, embedded in paraffin and stained with Masson's trichrome, hematoxylin and eosin (H&E). The fibroblasts and collagen density were counted using a light microscope and computerized image analysis system and calculated as the density and the percent. A Student t-test showed a significantly higher wound healing rate of the HVPCS group than control (t=-4.161, p<0.001). The fibroblasts in the HVPCS group were higher than in the control group (t=-4.921, p<0.001). The density of collagen in the HVPCS group was also higher than in the control group (t=-4.367, p<0.001). These results indicate that the HVPCS accelerated the rate of healing in dermal wound, and increased fibroblasts and collagen density in the regenerative dermis. These findings suggest that the HVPCS may activate fibroblasts by alteration of the electrical environment, and it may increase collagen synthesis in the regenerative dermal wound.

• Journal of Dental Rehabilitation and Applied Science
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• v.26 no.4
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• pp.477-482
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• 2010

In a case of multiple posterior teeth loss, antagonistic teeth extrude to the edentulous space and compensatory occlusion on the remained anterior teeth leads to occlusal trauma. Extrusion of antagonistic teeth breaks down occlusion plane and loss of posterior support bring about severe wear of remained teeth. In this situation, it is needed to restore remained teeth and edentulous space by increasing vertical dimension to obtain prosthodontic rehabilitation space and to correct occlusion plane. In this case report, the patient had a masticatory problem with loss of posterior teeth support and an esthetic problem of shortened anterior teeth. Before the tooth preparation for the prosthodontic restoration, the patient used removable device for 2 months to increase vertical dimension reversibly. After that, he got provisional fixed restoration with irreversible tooth reduction and used it for 3 months. It had spent 5 month to evaluate the adaptation state on final restoration with incresed vertical dimension. The increasing amount was 3 mm, which was relatively in less degree and masticatory system adapted to the increased vertical dimension without any pathologic changes. Final restoration was made to have equal-intensity contacts on all teeth in a verifiable centric relations and immediate disclusion of all posterior contacts the moment the mandible moves in any direction from centric relation. In addition, metal occlusion surface on posterior teeth was applied to prevent excessive muscle activation, occlusal trauma and the porcelain fracture.

• 한국해양학회지
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• v.26 no.2
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• pp.117-132
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• 1991

Marine total magnetic intensity over the southern part of the Ulleung Basin and geomagnetic data measured at a land base station are analyzed. Fourteen days observation of geomagnetic field at a fixed on-land base station showed how the geomagnetic field around the study area behaves. geomagnetic data at the base station can also be used as correction data for a diurnal variation. Magnetic anomalies in the study area do not reflect an effect of sea bottom topography but mainly subsurface basement. The southern part of the Ulleung Basin can be devided into two zones according to a different anomaly pattern; along the coastal shelves the isolated anomalies with a short wave and a strong amplitude are dominant, and toward the open sea the anomalies become much more subdued. The high anomaly zone adjoined to land is interpreted to be caused by granitic intrusives or volcanic rocks, and the weak anomaly zone to the outer sea to be arisen from an existence of deep basement. A spectrum analysis is applied to estimate magnetic basement depths from three anomaly profiles with a long period and a weak amplitude toward the outer sea. The calculated depths are 7.0km, 5.0km, and 2.6km respectively from outer profile. The basement might be correlated with the mixed layer of tuff, basalt, and sediment, which had been defined as L-2 layer in the Yamato basin and the Japan Basin.

• Journal of Technology Innovation
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• v.26 no.1
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• pp.85-105
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• 2018

This study analyzes the economic impacts of Korean R&D expenditure on the industrial structure by technological levels using 2010~2014 Input-Output table data. The industrial structure is reclassified into 4 manufacturing industries by OECD's Technology Intensity Definition. Then, we analyzes the production-inducing and value added-inducing of those industries. As the results of the analysis, it is found that the production-inducing effect by the R&D expenditure has been higher in the middle-high and middle-low technology manufacturing and that the value added-inducing effect has been higher in the middle-high technology manufacturing. On the other hand, the production and value added-inducing effects has been lower in the high-tech manufacturing which is highest in the R&D expenditure. The above results indicate that industrial structure has not been linked with the quality ladder that expresses the enhancement of tech level through R&D expenditure. Based on these results, the policy recommendation implies that R&D expenditure should be concentrated to improve the production- and value-added effects of the high technology manufacturing in order to advance the industrial structure. However, this study has the limitation that the analyses on the dynamic-inducing effects are not carried out due to the lack of fixed capital formation data.

• Fire Science and Engineering
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• v.20 no.2 s.62
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• pp.44-53
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• 2006

We have conducted a numerical simulation under two-dimensional unsteady conditions in order to analyze the effect according to the injection angle and velocity of the $CO_2$ agent nozzle which is one of the elements for the fixed type $CO_2$ fire extinguishing system installed in a ship on the characteristics of flow and $CO_2$ concentration distribution. The flow fields and concentration fields were measured and analyzed. We can found that the difference of flow patterns according to the conditions of $CO_2$ agent injection nozzle, and in all the conditions of $CO_2$ agent injection nozzle, the iso-concentration line was expanded from the region at which vortex was generated to the surroundings. We can expected that the intensity of the wall jet on the bottom floor was generated differently and the iso-concentration lines were expanded or shrunk according to the angle of $CO_2$ agent injection nozzle. In case of increasing $CO_2$ agent injection velocity maintaining the flow quantity of the $CO_2$ agent injection equally, the iso-concentration line of $CO_2$ agent on bottom floor can be formed more higher than in case of decreasing $CO_2$ agent injection velocity.

• The Korea Journal of Herbology
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• v.25 no.1
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• pp.75-81
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• 2010

Objectives : It was investigated new herbal prescription HT005 supported by traditional Korean medicine has a activity on the longitudinal bone growth of rats. HT005 were consisted of the root of Angelica sinensis, the fruit of Alpinia oxyphylla, the root of Astragalus membranaceus, the stem of Eleutherococcus senticosus, and the root of Dioscorea japonica, and Poria cocos. Method : To investigate the effect on longitudinal bone growth in adolescent male Sprague-Dawley rats, the longitudinal length of growth plate was measured directly by the tetracycline fluorescent labeling method and chondrocyte staining method. HT005 administered orally for four days, and the tetracycline was injected twice on the growth plate of the animals for fluorescent dying. The rate of longitudinal bone growth was measured the length between the tetracycline bands which fixed on the 3rd day and 5th day after injection. Cresyl violet was also used to stain the chondrocytes in the growth plate. The length of growth plate after administration was compared. Expression of IGF-1 and BMP-2 in the growth plate was investigated by immunohistochemistry. Results : HT005 showed a significant longitudinal bone growth which was $301.0{\pm}6.1\;{\mu}m/day$ at the dose of 100 mg/kg and $283.8{\pm}1.25\;{\mu}m/day$ (p < 0.001)at the dose of 10 mg/kg of HT005, compared to control group by the tetracycline fluorescent labeling method. HT005 showed a significant chondrocyte length on growth plate which was measured $797.19{\pm}3.31\;{\mu}m$ (p < 0.001) at the dose of 100 mg/kg and $720.14{\pm}2.19$ (p < 0.001) ${\mu}m$ at the dose of 10 mg/kg compared to the control group by cresyl-violet staining method. Both the number and intensity of BMP-2 and IGF-1 positive cells were increased in the hypertrophic zone of growth plate. There was a significant correlation between BMP-2 and IGF-1 expression and heights of chondrocytes in growth plate. Conclusions : Treatment of HT005 on Sprague-Dawley rats markedly increased the longitudinal bone growth. Therefore, HT005 may be an alternative herbal source to growth hormone as it promotes bone growth in children afflicted by growth retardation.

• 한국문화재보존과학회:학술대회논문집
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• 2004.10a
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• pp.15-24
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• 2004

The Seokgatap pagoda composed of mainly alkali granite and other minor pink-feldspar granite, fine-grained granite, granodiorite, diorite, gabbro, and tuff. Despite the small loss and damage derived from joints, its peel-off and exfoliation are serious enough to cause the heavy deterioration on the stone surface. The chemical and petrological weathering has partly replaced the original rock-forming minerals with clay minerals and iron oxyhydroxides. Based on the petrogenesis, rock materials of the pagoda is very similar to rocks of Dabotap pagoda and the Namsan granite in the Gyeongju. The central fart of the pagoda has sunken highly, which caused all the corners to split and the structural transformation to become worse. The reverse V-shaped gaps between the materials have broken stones filled in a coarse way. The iron plates inserted between the upper flat stone laid on other stones and tile pagoda body in the north and east side has been exposed in the air and corroded, discoloring of the adjacent stones. The overall diagnosis of the Seokgatap pagoda is the deteriorated functions of the stone materials, which calls for a long-term monitoring and plans to reinforce the stone surfaces. But the main body including the pagoda roof stone needs washing on a regular basis, and the many different cracks should be fixed with glue by using the fillers or hardeners designed for stone cultural properties after removing the cement mortar. In case of the replacement of the stone materials with new stones, it's necessary to examine the pagoda for the center of gravity and support intensity of the materials. The structural stability of the pagoda can be attained by taking a reinforce measure in geotechnical engineering and making a drainage. The ground humidity, which has aggravated weathering and structural instability, should be resolved by setting up a humidity reduction facility. The contamination of lichens and bryophyte around the pagoda and on the surface is serious. Thus biochemical treatments should be given too in order to prevent further biological damages and remove the vegetation growing on the discontinuous planes.