• 대한전자공학회논문지SD
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• 제37권11호
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• pp.59-66
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• 2000

본 논문에서는 DSP에서 필수적인 고속 저 전력 조건 선택 덧셈기/뺄셈기의 마크로 셀 라이브러리를 설계, 구축하였다. 덧셈기의 Carry전달 지연 시간을 최소로 하기 위한 CLA 기법과 연산 가능한 모든 결과 값을 미리 계산한 후 선택하는 조건 선택 기법을 적용하였다. 또한 이러한 설계방법이 8비트에서 64비트까지 자동 생성될 수 있도록 전용 프로그램을 작성하고 셀 기반 설계기법을 도입하여 Auto P&R Tool과 연계하여 자동으로 레이아웃이 가능하도록 하였다. 제안된 덧셈기/뺄셈기는 0.25${\mu}m$, 1-Poly, 5-Metal, N-well CMOS 공정을 사용하여 제작되었으며, 2.5V 단일 공급전압에서 지연시간, 소모 전력을 측정하였다. 측정결과 32 비트 덧셈기/뺄셈기의 경우 3.43ns의 지연시간과 42.8${\mu}w$/MHz의 전력소비를 나타내었다.

• Biomolecules & Therapeutics
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• 제24권5호
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• pp.536-542
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• 2016

Shuangdan oral liquid (SDO) containing radix Salviae miltiorrhizae (Chinese name Danshen) and cortex moutan (Chinese name Mudanpi) is a traditional Chinese medicine using for treating vascular diseases. Danshensu (DSS) is a main effective monomer composition derived from radix Salviae miltiorrhizae and paeonol (Pae) from cortex moutan. Although the two herbs are widely used in traditional Chinese medicine, the pharmacological functions of their active compositions were not reported. Therefore, the research of DSS and Pae in mechanisms and pharmacodynamics interaction can provide scientific evidence to support clinical application. The diabetic nephropathy (DN) rats which were induced by streptozotocin (STZ) were treated with SDO, DSS, Pae, and DSS+Pae for eight weeks. The positive effects on DN animal models were investigated by detection of physiological and biochemical indexes and oxidative stress markers, within five treatments: SDO, DSS, Pae, DSS+Pae and insulin group. Compared with the model group, the DSS+Pae group improved the renal function, blood lipid metabolism and blood viscosity, increased the vitality of T-SOD or T-AOC and decreased the level of MDA or NO after the treatment. The study was successfully showed that the DSS+Pae group could delay the process of DN, especially in the renal injury part of histopathology changes. Our results suggest that the co-administration of DSS and Pae significantly may play a protective role in DN rats through decreasing the oxidative stress and improving the blood lipid metabolism mechanisms.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.188-188
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• 2017

Rice (Oryza sativa L.) is one of the major crops that is seriously impacted by global soil salinization. Rice is among those crops where most of the high-yielding cultivars are highly sensitive to salinity. The key to a plant survival under NaCl salt stress is by maintaining a high $K^+/Na^+$ ratio in its cells. Selection for salinity tolerance genotypes of rice based on phenotypic performance alone is less reliable and will delay in progress in breeding. Recent advent of molecular markers, microsatellites or simple sequence repeats (SSRs) were used to find out salt tolerant rice genotypes. In the current experiment phenotyping and genotyping studies were correlated to differentiate different rice accessions for salinity tolerance. Eight rice accessions along with check plant Dongjin were screened by physiological studies using Yoshida solution with 50mM NaCl stress condition. The physiology studies identified four tolerant and four susceptible accessions based on their potassium concentration, sodium concentration, $K^+/Na^+$ ratio and biomass. 17 SSR markers were used to evaluate these rice accessions for salt tolerance out of which five molecular markers were able to discriminate tolerant accessions from the susceptible accessions. Banding pattern of the accessions was scored comparing to the banding pattern of Dongjin. The study identifies accessions based on their association of $K^+/Na^+$ ratio with molecular markers which is very reliable. These markers identified can play a significant role in screening large set of rice accessions for salt tolerance; these markers can be utilized to improve salt tolerance of commercial rice varieties with marker-assisted selection (MAS) approach.

• 화약ㆍ발파
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• 제23권1호
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• pp.65-77
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• 2005

최근 도심지 고층 구조물의 수가 증가하면서 수명이 오래된 구조물에 대한 재건축 수요가 증가하고 있는 실정이다. 기존 구조물을 철거하는 방법에는 기계식 해체 공법과 발파 해체공법이 있으나 10여층 이상의 고층건물일 경우 발파해체공법을 사용하는 겅이 경제적으로 유리한 것으로 알려져 있다. 발파해체공법을 사용할 경우, 발파에 앞서 미리 그 붕괴거동을 예측하는 일은 안전한 발파를 위해서 뿐만 아니라 발파해체의 실패를 방지하기 위해서 필수적으로 요구된다. 과거의 연구에서 이차원 입자결합모델을 사용하여 구조물 해체과정을 모사한 사례가 있었지만, 실제 발파붕괴 거동을 적절히 모사하는 데는 많은 제약이 있었다. 본 연구에서는 개별요소법을 기반으로 입자결합모델을 사용한 상용 프로그램인 PFC3D를 사용하여 구조물의 3차원 해체발파를 모사하였다. 삼차원 해석에서는 해석 시간이 오래 걸리는 단점으로 인하여 현실에 가까운 모사를 완성할 수 없었지만 몇 가지 입력변수를 바꾸어가며 그들의 효과를 관찰하였다. 보다 현실에 가까운 결과를 얻기 위해서는 입력변수의 설정과 부재 특성의 모사에 보다 많은 노력이 필요할 것으로 보인다.

• Toxicological Research
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• 제17권3호
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• pp.225-234
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• 2001

The present study was conducted to investigate the effects of Korean red ginseng water extract (KRGWE) on developmental toxicity caused by the environmental estrogen bisphenol A (BPA) in Sprague-Dawley rats. fifty males successfully mated were randomly assigned to five experimental groups, 1.e., group I (vehicle control), group II (BPA 1000mg/kg), group III (KRGWE 400mg/kg), group IV (BPA 1000mg/kg & KRGWE 200mg/kg), and group V (BPA 1000mg/kg & KRGWE 400mg/kg). The test articles were administered by gavage to mated females from gestational days (GD) 1 through 20 (sperm vaginal lavage=day O). All females were subjected to caesarean section on GD 21 and their fetuses were examined for external, visceral, and skeletal abnormalities. In the group II, significant maternal toxic effects including suppressed body weight, decreased body weight gain during pregnancy, and reduced food consumption were observed in pregnant rats. The minimal developmental toxicity including fetal ossification delay was also found in fetuses. In addition, a tendency for increased pregnancy failure, increased pre-and postimplantation loss, and decreased fetal body weight was observed. However, no fetal morpho-logical abnormalities were seen in surviving fetuses at a dose level of 1000mg BPA/kg. On the other hand, the maternal toxicity and developmental toxicity found in the groups IV and V were comparable to those of the group II. There were no adverse signs of either maternal toxicity or developmental toxicity in the group III. These results showed that administration of BPA at a dose level of 1000mg/kg to pregnant rats resulted in significant maternal toxicity and minimal developmental toxicity, and that no protective effects on BPA-induced maternal toxicity and developmental toxicity were found by concomitant gavage dosing of KRGWE.

• Clinics in Shoulder and Elbow
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• 제23권3호
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• pp.144-151
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• 2020

Background: This study was designed to evaluate characters of the rotator cuff tear (RCT) recognized after primary shoulder dislocation in patients older than 40. Methods: From 2008 to 2019, patients who visited two hospitals after dislocation were retrospectively reviewed. Inclusion criteria were patients over 40 who had dislocation, with magnetic resonance imaging (MRI) undergone. Exclusion criteria were patients who lost to follow-up, combined with any proximal humerus fracture, brachial plexus injury, and previous operation or dislocation history in the ipsilateral shoulder. Also patients who had only bankart or bony bakart lesion in MRI were excluded. We evaluated RCTs that were recognized by MRI after the primary shoulder dislocation with regard to tear size, degree, involved tendons, fatty degeneration, the age when the first dislocation occurred, and the duration until the MRI was evaluated after the dislocation. Results: Fifty-five RCTs were included. According to age groups, the tear size was increased in coronal and sagittal direction, the number of involved tendons was increased, and the degree of fatty degeneration was advanced in infraspinatus muscle. Thirty-two cases (58.2%) conducted MRI after 3 weeks from the first shoulder dislocation event. This group showed that the retraction size of the coronal plane was increased significantly and the fatty accumulation of the supraspinatus muscle had progressed significantly. Conclusions: Age is also a strong factor to affect the feature of RCT after the shoulder dislocation in patients over 40. And the delay of the MRI may deteriorate the degree of tear size and fatty degeneration.

• 한국통신학회논문지
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• 제21권6호
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• pp.1490-1500
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• 1996

비디오 데이터를 전송할 때 채널 대역 효율을 최대화하는 문제 때문에 ATM망에서 멀티미디어 통신의 중요한 사항은 효과적인 망입력 데이터들의 활용문제이다. ATM 망에서 MPEG 입력데이타의 효과적 대역폭 추정방식을 제안하였다. MPEG 데이터의 무작위, 대용량 특성으로 인하여 효과적으로 전송 대역폭을 할당하는 문제는 일반적으로 어려운 문제이다. MPEG 트래픽 스트림을 서비스처리 속도, 버스트 입력율, 버스트간 입력율, 버스트 주기, 버스트 간격 주기으 5가지 트래픽 파라미터를 사용하여 모델링하였다. 각 데이터 입력원의 전송대역폭을 추정할 수 있었으며, 버퍼의 큐(queue)용량을 줄이기 위하여 이 추정된 대역폭을 동기식으로 적용하였다. 많은 수의 가상 회로 접속을 다중화한 고속 링크의 망모델에서 적응 대역 할당 방식의 성능을 시뮬레이션 하였다. 그 결과 고정 대역 할당 방식에 비하여 큐잉 지연이 상당히 감소되었다.

• 대한구순구개열학회지
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• 제11권1호
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• pp.1-12
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• 2008

In cleft palate patient, characteristic of speech disorder is the resonance disorder result from velopharyngeal incompetence. Clinically VPI caused by congenital factor as congenital palatal incompetence, submucosal cleft palate, and caused by acquired factor as CNS damage, tumor, palatal palsy. The clinicians more concerned about the speech disorders after cleft palate surgery rather than language pathologist. The resonance disorder devided for hypernasality, hyponasality and nasal emission, but as a rule, hypernasality is typical phenomenon of the resonance disorder. Traditionally clinicians and language pathologists evaluated four-stage or five-stage of hypernasality by subjective assessment. Although language pathologist is well-trained, results of the language level should be different. In late 1980s, Kay Elemetrics Corp. developed nasometer that objective nasalance identified with well-trained language pathologist and originate from nasometer Tonar I and II were developed by Fletcher. Therefore objective nasalance test was possible, the nasometer used in hospital, collage and speech clinic both and home and abroad. Standardization of the cleft palate speech assessment must be settled without delay because of different character result in different language and different assessment results by dialect in same language. In our study, we provide the data base for the standardization of cleft palate speech assessment which through report of objective assessment method, speech therapy effects and problems result in interdisciplinary teamwork by nasometer use in treatment of cleft palate patient.

• Journal of Power Electronics
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• 제18권1호
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• pp.225-233
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• 2018

This paper proposes a universal system control strategy for voltage source converter (VSC) based high voltage direct current (HVDC) systems. The framework of the designed control strategy consists of five layer structures considering the topology and control characteristics of the VSC-HVDC system. The control commands sent from the topmost layer can be transmitted to the next layer based on the existing communication system. When the commands are sent to each substation, the following transmission of commands between the four lower layers are realized using the internal communication system while ignoring the communication delay. This hierarchical control strategy can be easily applied to any VSC-HVDC system with any topology. Furthermore, an integrated controller for each converter is designed and implemented considering all of the possible operating states. The modular-designed integrated controller makes it quite easy to extend its operating states if necessary, and it is available for any kind of VSC. A detailed model of a VSC-HVDC system containing a DC hub is built in the PSCAD/EMTDC environment. Simulation results based on three operating conditions (the start-up process, the voltage margin control method and the master-slave control method) demonstrate the flexibility and validity of the proposed control strategy.

• 한국컴퓨터정보학회논문지
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• 제15권9호
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• pp.99-107
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• 2010

본 논문에서는 기존의 단일 보안 시스템의 Firewall과 IPS 시스템의 문제점 분석을 통하여 통합보안 시스템 강화가 비용 대비 효율적임을 나타내었다. 문제점 분석 결과 Firewall과 IPS 의 처리 시간 지연과 효율성 부재를 나타냈다. 따라서 개별 Firewall과 IPS 시스템과 통합 시스템으로 성능 평가를 하였다. 평가 결과 기존 시스템 보다 제안한 통합보안시스템이 응답 처리 시간에서는 평균 5배 이상 성능을 나타났고, 초당 세션 처리에서도 5배 이상 그리고 CPU 처리 성능에서는 6배의 처리 속도가 우수함을 나타냈다. 또한 여러 보안 정책들을 수용하였고, 유해 트랙픽 처리에서도 높은 성능을 나타났다. 결론적으로 본 논문에서는 통합 보안 시스템이 개별 시스템 강화 보다 경제적 측면, 관리적 측면, 물리적 측면, 시간적 측면, 공간적 측면 등 여러 측면에서 효율적임을 강조하였다.