• Title/Summary/Keyword: finite-element modeling

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Computational Analysis of Tumor Angiogenesis Patterns Using a Growing Brain Tumor Model

  • Shim, Eun-Bo;Kwon, Young-Keun;Ko, Hyung-Jong
    • International Journal of Vascular Biomedical Engineering
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    • v.2 no.1
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    • pp.17-24
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    • 2004
  • Tumor angiogenesis was simulated using a two-dimensional computational model. The equation that governed angiogenesis comprised a tumor angiogenesis factor (TAF) conservation equation in time and space, which was solved numerically using the Galerkin finite element method. The time derivative in the equation was approximated by a forward Euler scheme. A stochastic process model was used to simulate vessel formation and vessel elongation towards a paracrine site, i.e., tumor-secreted basic fibroblast growth factor (bFGF). In this study, we assumed a two-dimensional model that represented a thin (1.0 mm) slice of the tumor. The growth of the tumor over time was modeled according to the dynamic value of bFGF secreted within the tumor. The data used for the model were based on a previously reported model of a brain tumor in which four distinct stages (namely multicellular spherical, first detectable lesion, diagnosis, and death of the virtual patient) were modeled. In our study, computation was not continued beyond the 'diagnosis' time point to avoid the computational complexity of analyzing numerous vascular branches. The numerical solutions revealed that no bFGF remained within the region in which vessels developed, owing to the uptake of bFGF by endothelial cells. Consequently, a sharp, declining gradient of bFGF existed near the surface of the tumor. The vascular architecture developed numerous branches close to the tumor surface (the brush-border effect). Asymmetrical tumor growth was associated with a greater degree of branching at the tumor surface.

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Effects of Acoustic Boundary Conditions on Combustion Instabilities in a Gas Turbine Combustor (음향 경계 조건이 가스터빈 연소기에서의 연소불안정에 미치는 영향)

  • Lim, Jaeyoung;Kim, Deasik;Kim, Seong-Ku;Cha, Dong Jin
    • Journal of the Korean Society of Propulsion Engineers
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    • v.19 no.4
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    • pp.15-23
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    • 2015
  • This study predicts the basic characteristics of combustion instabilities in a gas turbine lean premixed combustor using ASCI3D code which is a FEM(Finite Element Method)-based Helmholtz solver. The prediction results show the good agreement with the measured data in modeling the overall combustion instability features, however, the code is found to overpredict the unstable conditions. As one of the efforts to improve the model accuracy, the effects of acoustic boundary conditions on the instability growth rate are analyzed. As a result, it is shown that the acoustic reflection coefficient has a great impact on the instability and the prediction accuracy can be enhanced by defining the precise acoustic conditions.

Geomechanical and thermal reservoir simulation during steam flooding

  • Taghizadeh, Roohollah;Goshtasbi, Kamran;Manshad, Abbas Khaksar;Ahangari, Kaveh
    • Structural Engineering and Mechanics
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    • v.66 no.4
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    • pp.505-513
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    • 2018
  • Steam flooding is widely used in heavy oil reservoir with coupling effects among the formation temperature change, fluid flow and solid deformation. The effective stress, porosity and permeability in this process can be affected by the multi-physical coupling of thermal, hydraulic and mechanical processes (THM), resulting in a complex interaction of geomechanical effects and multiphase flow in the porous media. Quantification of the state of deformation and stress in the reservoir is therefore essential for the correct prediction of reservoir efficiency and productivity. This paper presents a coupled fluid flow, thermal and geomechanical model employing a program (MATLAB interface code), which was developed to couple conventional reservoir (ECLIPSE) and geomechanical (ABAQUS) simulators for coupled THM processes in multiphase reservoir modeling. In each simulation cycle, time dependent reservoir pressure and temperature fields obtained from three dimensional compositional reservoir models were transferred into finite element reservoir geomechanical models in ABAQUS as multi-phase flow in deforming reservoirs cannot be performed within ABAQUS and new porosity and permeability are obtained using volumetric strains for the next analysis step. Finally, the proposed approach is illustrated on a complex coupled problem related to steam flooding in an oil reservoir. The reservoir coupled study showed that permeability and porosity increase during the injection scenario and increasing rate around injection wells exceed those of other similar comparable cases. Also, during injection, the uplift occurred very fast just above the injection wells resulting in plastic deformation.

The dynamic response and seismic damage of single-layer reticulated shells subjected to near-fault ground motions

  • Zhang, Ming;Parke, Gerry;Chang, Zhiwang
    • Earthquakes and Structures
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    • v.14 no.5
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    • pp.399-409
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    • 2018
  • The dynamic response and seismic damage of single-layer reticulated shells in the near field of a rupturing fault can be different from those in the far field due to the different characteristics in the ground motions. To investigate the effect, the dynamic response and seismic damage of this spatial structures subjected to two different ground motions were numerically studied by nonlinear dynamic response analysis. Firstly, twelve seismic waves with an apparent velocity pulse, including horizontal and vertical seismic waves, were selected to represent the near-fault ground motion characteristics. In contrast, twelve seismic records recorded at the same site from other or same events where the epicenter was far away from the site were employed as the far-fault ground motions. Secondly, the parametric modeling process of Kiewitt single-layer reticulated domes using the finite-element package ANSYS was described carefully. Thirdly, a nonlinear time-history response analysis was carried out for typical domes subjected to different earthquakes, followed by analyzing the dynamic response and seismic damage of this spatial structures under two different ground motions based on the maximum nodal displacements and Park-Ang index as well as dissipated energy. The results showed that this spatial structures in the near field of a rupturing fault exhibit a larger dynamic response and seismic damage than those obtained from far-fault ground motions. In addition, the results also showed that the frequency overlap between structures and ground motions has a significant influence on the dynamic response of the single-layer reticulated shells, the duration of the ground motions has little effects.

Seismic behavior of stiffened concrete-filled double-skin tubular columns

  • Shekastehband, B.;Mohammadbagheri, S.;Taromi, A.
    • Steel and Composite Structures
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    • v.27 no.5
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    • pp.577-598
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    • 2018
  • The imperfect steel-concrete interface bonding is an important deficiency of the concrete-filled double skin tubular (CFDST) columns that led to separating concrete and steel surfaces under lateral loads and triggering buckling failure of the columns. To improve this issue, it is proposed in this study to use longitudinal and transverse steel stiffeners in CFDST columns. CFDST columns with different patterns of stiffeners embedded in the interior or exterior surfaces of the inner or outer tubes were analyzed under constant axial force and reversed cyclic loading. In the finite element modeling, the confinement effects of both inner and outer tubes on the compressive strength of concrete as well as the effect of discrete crack for concrete fracture were incorporated which give a realistic prediction of the seismic behavior of CFDST columns. Lateral strength, stiffness, ductility and energy absorption are evaluated based on the hysteresis loops. The results indicated that the stiffeners had determinant role on improving pinching behavior resulting from the outer tube's local buckling and opening/closing of the major tensile crack of concrete. The lateral strength, initial stiffness and energy absorption capacity of longitudinally stiffened columns with fixed-free end condition were increased by as much as 17%, 20% and 70%, respectively. The energy dissipation was accentuated up to 107% for fixed-guided end condition. The use of transverse stiffeners at the base of columns increased energy dissipation up to 35%. Axial load ratio, hollow ratio and concrete strength affecting the initial stiffness and lateral strength, had negligible effect of the energy dissipation of the columns. It was also found that the longitudinal stiffeners and transverse stiffeners have, respectively, negative and positive effects on ductility of CFDST columns. The conclusions, drawn from this study, can in turn, lead to the suggestion of some guidelines for the design of CFDST columns.

The actuation equation of macro-fiber composite coupled plate and its active control over the vibration of plate and shell

  • Tu, Jianwei;Zhang, Jiarui;Zhu, Qianying;Liu, Fan;Luo, Wei
    • Structural Monitoring and Maintenance
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    • v.5 no.2
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    • pp.297-311
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    • 2018
  • Plate and shell structure is widely applied in engineering, i.e. building roofs, aircraft wings, ship platforms, and satellite solar arrays. Its vibration problem has become increasingly prominent due to the tendency of lightening, upsizing and flexibility. As a new smart material with great actuating force and toughness, macro-fiber composite (MFC) is composed of piezoelectric fiber and epoxy resin basal body, which can be directly pasted onto the surface of plate and shell and is suitable for vibration control. This paper deduces the actuation equation of MFC coupled plate in different boundary conditions, an equivalent finite element modeling method is proposed which uses MFC actuating force as the applied excitation, and on this basis the active control simulation and experiment of MFC over plate and shell structure vibration are accomplished. The results indicate that MFC is able to implement effective control over plate and shell structure vibration in multi-band range. The comparison between experiment and simulation proves that the actuation equation deduced herein, effective and practicable, can be applied into the simulation calculation of MFC vibration control over plate and shell structure.

Detector Mount Design for IGRINS

  • Oh, Jae Sok;Park, Chan;Cha, Sang-Mok;Yuk, In-Soo;Park, Kwijong;Kim, Kang-Min;Chun, Moo-Young;Ko, Kyeongyeon;Oh, Heeyoung;Jeong, Ueejeong;Nah, Jakyoung;Lee, Hanshin;Jaffe, Daniel T.
    • Journal of Astronomy and Space Sciences
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    • v.31 no.2
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    • pp.177-186
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    • 2014
  • The Immersion Grating Infrared Spectrometer (IGRINS) is a near-infrared wide-band high-resolution spectrograph jointly developed by the Korea Astronomy and Space Science Institute and the University of Texas at Austin. IGRINS employs three HAWAII-2RG Focal Plane Array (H2RG FPA) detectors. We present the design and fabrication of the detector mount for the H2RG detector. The detector mount consists of a detector housing, an ASIC housing, a Field Flattener Lens (FFL) mount, and a support base frame. The detector and the ASIC housing should be kept at 65 K and the support base frame at 130 K. Therefore they are thermally isolated by the support made of GFRP material. The detector mount is designed so that it has features of fine adjusting the position of the detector surface in the optical axis and of fine adjusting yaw and pitch angles in order to utilize as an optical system alignment compensator. We optimized the structural stability and thermal characteristics of the mount design using computer-aided 3D modeling and finite element analysis. Based on the structural and thermal analysis, the designed detector mount meets an optical stability tolerance and system thermal requirements. Actual detector mount fabricated based on the design has been installed into the IGRINS cryostat and successfully passed a vacuum test and a cold test.

Flexural Performance of Multistage Prestressed and Self-weight Preflex Girder (다단계 자중 프리플렉스 및 프리스트레싱 합성거더의 시공단계에 따른 휨성능 평가)

  • Choi, Byung Ho;Kim, Tae Bong;Park, Sung Kyun
    • Journal of Korean Society of Steel Construction
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    • v.29 no.4
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    • pp.311-321
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    • 2017
  • This paper deals with the flexural performance of a composite girder system designed to readily form a composite section without a formwork and to easily realize multistage preflexing and prestressing. After a 3-Dimensional finite element modeling for construction stage analysis, the parametric numerical analysis was performed to analyse the stress distribution on the composite girder sections and the prestressing effects along with concrete pouring method and strand tensioning method. Based on the stress distribution analysis, a favorable construction stage model has been rationally chosen and then the ultimate flexural strengths were evaluated to conduct a comparative study, which exceed the nominal flexural strength suggested by the current design specification(ASD). It can be concluded that the proposed composite girder and fabrication procedure should have a sufficient structural performance.

Analysis of Facilitated Olefin Transport Through Polymer Electrolyte Membranes Containing Silver Salts (은염을 포함하는 고분자 전해질 막을 통한 올레핀 촉진수송의 해석)

  • Yong Soo Kang;Dongkyun Ko;Jong Hak Kim;Sung Taik Chung
    • Membrane Journal
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    • v.13 no.4
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    • pp.239-245
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    • 2003
  • The origin of large difference of selectivity of $C_3H_6$ over $C_3H_8$ between pure gas and mixed gas through silver polymer electrolyte membranes is investigated. Firstly, the effect of feed condition on the permeance of mixture gas ($C_3H_6/C_3H^8$) and the separation performance is examined. Upon decrease of the $C_3\;H_6$ concentration, the $C_3H_6$ permeance decreased whereas the permeance of $C_3H_8$ increased, resulting in the decrease of the selectivity of $C_3H_6/C_3H_8/.$ This result is ascribed to the $C_3H_6$-induced plasticization of membranes. Experimental results were validated by means of mathematical modeling, where pressure independent permeabilities were used.

Design of piezoelectric micro-machined ultrasonic transducer for wideband ultasonic radiation in air (공기 중 광대역 초음파 방사용 압전 박막 기반 초소형 초음파 트랜스듀서의 설계)

  • Ahn, Hongmin;Jin, JaeHyeok;Moon, Wonkyu
    • The Journal of the Acoustical Society of Korea
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    • v.39 no.2
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    • pp.87-97
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    • 2020
  • In this paper, the design of piezoelectric Micro-machined Ultrasonic Transducer (pMUT) for wideband ultrasonic radiation in air was investigated. One of the methods to achieve wide frequency bandwidth in single device is modeling the transducer to multi-resonance system. The new pMUT was designed as a multi-resonance system with the addition of a suitable acoustic structure to the front and back of a thin film structure. A new pMUT consisting of thin film parts, radiation parts, and packaging parts is designed with a Lumped Parameter Model (L.P.M). Finally, it was validated as a Finite Element Method (FEM) simulation. The final designed pMUT achieved a frequency band of 102 kHz ~ 132 kHz (-3 dB).