• Title/Summary/Keyword: field screening

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Development of a System for Selecting High-Quality Mold Manufacturing NC Data Using Evaluating the NC Data (NC 데이터 정량화를 통한 고품질 사출금형 NC 가공데이터 선정 방안)

  • Heo Eun-Young;Kim Bo-Hyun;Kim Dong-Won
    • Journal of the Korean Society for Precision Engineering
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    • v.23 no.4 s.181
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    • pp.99-108
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    • 2006
  • Since mold industries are regarded as belonging to three types of bad business, capable young people are reluctant to work in this field. The industries are hard to employ skilled workers who have much experience and knowledge On the mold manufacturing. Thus, effective CAM systems are required for unskilled workers to create process plans and NC data for the manufacturing, and process plans play important roles in the downstream manufacturing processes, such as NC machining, polishing, and final assembly. This study proposes a decision support system that facilitates unskilled workers to easily select high quality NC-data, as well as to increase productivity. The proposed system is assumed to follow a CAM operation scenario that consists of next three steps: 1) identifying several process plans and enumerating feasible unit machining operations (UMOs) from material and part surface information, 2) creating all feasible NC-data based on UMOs using a commercial CAM system, 3) selecting the best NC data among the feasible NC data using four screening criteria, such as machining accuracy, machining allowance, cutting load, and processing time. A case study on the machining of a camera core mold is provided to demonstrate the proposed system.

Prevention and Early Detection of Occupational Cancers - a View of Information Technology Solutions

  • Davoodi, Somayeh;Safdari, Reza;Ghazisaeidi, Marjan;Mohammadzadeh, Zeinab;Azadmanjir, Zahra
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5607-5611
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    • 2015
  • Thousands of people die each year from cancer due to occupational causes. To reduce cancer in workers, preventive strategies should be used in the high-risk workplace. The effective prevention of occupational cancer requires knowledge of carcinogen agents. Like other areas of healthcare industry, occupational health has been affected by information technology solutions to improve prevention, early detection, treatment and finally the efficiency and cost effectiveness of the healthcare system. Information technology solutions are thus an important issue in the healthcare field. Information about occupational cancer in information systems is important for policy makers, managers, physicians, patients and researchers; because examples that include high quality data about occupational cancer patients and occupational cancer causes are able to determine the worker groups which require special attention. As a result exposed workers who are vulnerable can undergo screening and be considered for preventive interventions.

Computational Chemistry as a Key to Structural Bioinformatics

  • Kang, Young-Kee
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2000.11a
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    • pp.32-34
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    • 2000
  • Computational chemistry is a discipline using computational methods for the calculation of molecular structure, properties, and reaction or for the simulation of molecular behavior. Relating and turning the complexity of data from genomics, high-throughput screening, combinatorial chemical synthesis, gene-expression investigations, pharmacogenomics, and proteomics into useful information and knowledge is the primary goal of bioinformatics. In particular, the structure-based molecular design is one of essential fields in bioinformatics and it can be called as structural bioinformatics. Therefore, the conformational analysis for proteins and peptides using the techniques of computational chemistry is expected to play a role in structural bioinformatics. There are two major computational methods for conformational analysis of proteins and peptides; one is the molecular orbital (MO) method and the other is the force field (or empirical potential function) method. The MO method can be classified into ab initio and semiempirical methods, which have been applied to relatively small and large molecules, respectively. However, the improvement in computer hardwares and softwares enables us to use the ab initio MO method for relatively larger biomolecules with up to v100 atoms or ∼800 basis functions. In order to show how computational chemistry can be used in structural bioinformatics, 1 will present on (1) cis-trans isomerization of proline dipeptide and its derivatives, (2) positional preference of proline in ${\alpha}$-helices, and (3) conformations and activities of Arg-Gly-Asp-containing tetrapeptides.

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Knowledge Towards HPV infection and HPV Vaccines among Syrian Mothers

  • Alsaad, Mohammed A.;Shamsuddin, Khadijah;Fadzil, Fariza
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.3
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    • pp.879-883
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    • 2012
  • Cervical cancer is caused by HPV infection and can be prevented by early vaccination. Objective: To assess Syrian women's level of knowledge and determinants of good knowledge of cervical cancer, HPV infection and its vaccines. Methods: A cross sectional survey was undertaken among mothers with daughters in sixth grade classes enrolled in primary schools in Aleppo city, Syria. Samples were selected through cluster sampling and data collected using a self-administered questionnaire. Results: Less than a third of the mothers had heard of HPV infection and vaccines against cervical cancer and levels of knowledge were generally low. Good knowledge was associated with high education level, higher family monthly income, having few - less than four children, positive history of cervical cancer screening, and working or having relatives working in the medical field. The main source of information was television and few reported health care providers as a source of knowledge on HPV infection and vaccine. Conclusion: Since knowledge of HPV infection and its connection with cervical cancer and its vaccine are low, more efforts must be made to educate Syrians prior to introduction of any HPV vaccination programme. Public health efforts must focus on educating mothers, the public as well as health care providers.

Communication Patterns in Korean Families during BRCA Genetic Testing for Breast Cancer (BRCA 돌연변인 검사 중 유방암 환자 가족의 커뮤니케이션 패턴)

  • Anderson, Gwen;Jun, Myung-Hee;Choi, Kyung-Sook
    • Asian Oncology Nursing
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    • v.11 no.3
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    • pp.200-209
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    • 2011
  • Purpose: The purpose of this micro-ethnography is to examine whether science and societal changes impact family communication patterns among a convenience sample of 16 Korean women. Methods: The authors observed family communication in the context of a new breast cancer genetic screening and diagnostic testing program to detect BRCA gene mutations in Korean women at highest risk. Results: Analysis of in-depth interviews and field notes taken during participant observation illustrated that communication patterns in families vary according to a woman's position in the family. If a grandmother tests positive for a gene mutation, her daughters make decisions on her behalf; they open and maintain the communication channel among family members. If a housewife is diagnosed with cancer and a genetic mutation, she immediately consults her husband and her sisters. The husband creates an open communication channel between his wife, his parents and his siblings. As a result, a woman's cancer is a concern for the whole family not merely a woman's secret or crisis. Conclusion: Cultural differences are important to consider when designing new genetic service programs in different countries.

Central nervous system stimulating activity of the ethanolic extract of Fleurya interrupta Guad. (Urticaceae)

  • Shilpi, Jamil Ahmad;Rouf, Razina;Ferdous, MM;Uddin, Shaikh Jamal
    • Advances in Traditional Medicine
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    • v.6 no.1
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    • pp.21-26
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    • 2006
  • The ethanolic extract of Fleurya interrupta Gaud, (Urticaceae) was tested for its possible neuropharmacological effects on experimental animals, For the primary neuropharmacological screening of this plant, the ethanolic extract of its aerial parts was subjected to preliminary evaluation for acute toxicity, antinociceptive activity and central nervous system (CNS) activities. At the doses of 125 and 250 mg/kg, the extract significantly (P < 0.01 and P < 0. 001) and dose-dependently increased the frequency of acetic acid induced writhing in mice. In the pentobarbitone induced sleeping time test, the extract at the above dose levels, significantly and dose-dependently decreased the pentobarbitone induced sleeping time (P < 0.001) and increased the time for onset of sleep (P < 0.001) in mice. In the open field and hole cross tests, test animals showed an increase in their movement in the both tests from the 2nd observation period (30 min) and persisted throughout the entire experimental period (240 min). These results of the extract may attribute a stimulating action on the CNS. On the basis of these findings, it can be assumed that the extract exerts its stimulating effect on the CNS in mice by interfering with the cortical function or increasing the effect of some CNS stimulating neurotransmitters.

A simple screening technique for blast resistant mutants from the radiation irradiated rice populations (도열병저항성 변이계통의 선발을 위한 인공접종법)

  • Shin-Han Kwon;Jeong-Hae Oh;Hi-Sup Song
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.15
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    • pp.141-143
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    • 1974
  • An attempt was made to develop a simple testing method fro blast resistance in the aged rice plant grown under the paddy field conditions. The blast resistance was tested with the detached 3rd leaves from the top of the plant, which were inoculated by dropping blast spore suspension mixed with 1% Tween 20 on the punched area and kept in 1% sucrose solution. The blast reaction was measured ten days after incubation at 26-28$^{\circ}C$ under highly humid conditions. With this method blast resistant lines were effectively identified and the cost of testing was cheap as compared with any other methods ever practiced.

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Influense of the high-voltage conductivity on peculiarity of polarization ferroelectric polymer on based vinylidenefluoride

  • Kochervinskii, V.V.;Chubunova, E.V.;Lebedinskii, Y.Y.;Pavlov, A.S.;Pakuro, N.I.
    • Advances in materials Research
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    • v.4 no.2
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    • pp.113-132
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    • 2015
  • The phenomena of high-voltage polarization and conductivity in oriented vinylidenefluoride and tetrafluoroethylene copolymer films have been investigated. It was shown that under certain electric fields, injection of carriers from the material of electrodes appears The barrier for holes injection in the copolymer was found to be lower than that for electrons. It results in more effective screening of the external field near the anode than near cathode. Electrones, ejected from cathode, creating negative charge by trapping on the surface. It is shown that the electrons injected from cathodes create a negative homocharge on the copolymer surface and then become captured on the surface shallow traps. Their nature has been studied by the x-ray photoelectron spectroscopy. It was shown that these traps may consist of chemical defects in the form of new functional groups formed by reactions of surface macromolecules with sputtered atoms of aluminum. The asymmetric shape of hysteresis curves was explained by the difference in mobility of injected holes and electrons. These factors caused appearance of "non-closed" hysteresis curves for fluorine-containing polymer ferroelectrics. Hysteresis phenomena observed at low electric fields (below coercive ones) are to associate with the behavior of the domains localized in the ordered regions formed during secondary crystallization of copolymers.

Recent Trends of Advanced Biosensors for Mycotoxin Analysis

  • Shim, Won-Bo
    • 한국균학회소식:학술대회논문집
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    • 2016.05a
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    • pp.35-35
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    • 2016
  • A mycotoxin is a toxic secondary metabolite produced by organisms of the fungus kingdom, commonly known as molds and has been widely contaminated in agricultural products such as grains and cereals. Many methods including high performance liquid chromatography (HPLC) and gas chromatography (GC) have already been proposed and reviewed for mycotoxins. These methods are either expensive or time-consuming due to the complication of sample preparation and pre-concentration before determination. In addition, both methods are unsuitable for the routine screening of large sample numbers. A biosensor is a fictive analytical device that combines a biological component with a physicochemical detector for the detection of an analyte. Biosensors represent a rapidly expanding field, at the present time, with an estimated 60% annual growth rate; the major impetus coming from the health-care industry but with some pressure from other areas, such as food safety and environmental monitoring. Antibodies and aptamers are bioreceptors which have been used in the development of biosensors. There are many kinds of antibodies and aptamers specific to mycotoxin, and antibody (or aptamer)-based biosensors have been successfully developed for the detection of mycotoxin. The biosensors permit the rapid, sensitive, simple, and on-site detection of a range of mycotoxins and can be an alternative method to traditional methods such as HPLC and GC. This presentation provides the development trends of biosensors to mycotoxins and their application to food and agricultural products.

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Analysis of the Problems related to the Cumulative Trauma Disorders at Manufacturing Workplace and Development of a Risk Factor Checklist (제조업에서 발생하는 누적외상성질환 관련 문제점 분석 및 위험요인 점검표의 개발)

  • Park, Hee-Sok;Lee, Yun-Geun;Yim, Sang-Hyuk
    • Journal of Korean Institute of Industrial Engineers
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    • v.24 no.4
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    • pp.503-517
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    • 1998
  • Cumulative trauma disorders(CTDs) of the upper extremities among the workers at manufacturing workplace have become a serious problem in Korea. However, most of the studies on the CTDs carried out in this country have focused on the Video Display Terminal(VDT) operators. In fact, high rates of the CTDs have been reported for telecommunication employees, and the CTDs associated with VDT use in telecommunication industries pose great health and social problems in Korea today. On the other hand, there are few studies on the CTDs among the manufacturing workers, and the severity of the problem was much under-reported. This study reports and discusses the results of the literature review on the cross-sectional studies of the CTDs, along with the analysis of the problems associated with identification, medical examinations, and ergonomic evaluation of the disorders. Also a checklist was developed for the use of quick screening tool for risk factor analysis. Consistency of the checklist was validated with the field studies of several manufacturing workplace. Current issues and suggestions for future ergonomic studies are also addressed.

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