• 농업과학연구
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• 제50권4호
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• pp.817-828
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• 2023

Deteriorating soil physical properties and increasing soil pathogens due to the continuous cultivation of field crops are the leading causes of productivity deterioration. Crop rotation, soil heat treatment, and chemical control are used as pest control methods; however, each has limitations in wide application to domestic agriculture. In particular, chemical control requires improvement due to direct exposure to sterilizing solution, odor, and high-intensity work. To improve the overall domestic agricultural environment, the problems of time and cost, such as field maintenance and cultivation scale, must be addressed; therefore, mechanization technology for chemical control must be secured to derive improvement effects in a short period. Most related studies are focused on the control effect of the DMDS (dimethyl disulfide) sterilizer, and research on the performance of the sterilization spray device has been conducted after its introduction in Korea, but research on the corrosion suitability of the material is lacking. This study conducted a corrosion test to secure the corrosion resistance of a soil sterilizer injection pump, and a mechanical failure mode by corrosion by the material was established. The corrosion test comprised operation and neglect tests in which the sterilizing solution was circulated in the pump and remained in the pump, respectively. As a result of the corrosion test, damage occurred due to the weakening of the mechanical strength of the graphite material, and corrosion resistance to aluminum, stainless steel, fluororubber, and PPS (polyphenylene sulfide) materials was confirmed.

• IMMUNE NETWORK
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• 제20권1호
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• pp.7.1-7.11
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• 2020

Cancer immunotherapy, in the form of vaccination, adoptive cellular transfer, or immune checkpoint inhibitors, has emerged as a promising practice within the field of oncology. However, despite the developing field's potential to revolutionize cancer treatment, the presence of immunotherapeutic-resistant tumor cells in many patients present a challenge and limitation to these immunotherapies. These cells not only indicate immunotherapeutic resistance, but also show multi-modal resistance to conventional therapies, abnormal metabolism, stemness, and metastasis. How can immunotherapeutic-resistant tumor cells render multi-malignant phenotypes? We reasoned that the immune-refractory phenotype could be associated with multi-malignant phenotypes and that these phenotypes are linked together by a factor that acts as the master regulator. In this review, we discussed the role of the embryonic transcription factor NANOG as a crucial master regulator we named "common factor" in multi-malignant phenotypes and presented strategies to overcome multi-malignancy in immunotherapeutic-resistant cancer by restraining the NANOG-mediated multi-malignant signaling axis. Strategies that blunt the NANOG axis could improve the clinical management of therapy-refractory cancer.

• JSTS:Journal of Semiconductor Technology and Science
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• 제16권2호
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• pp.179-184
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• 2016

In recent years, the on-resistance, power loss and cell density of Si power devices have not exhibited significant improvements, and performance is approaching the material limits. GaN is considered an attractive material for future high-power applications because of the wide band-gap, large breakdown field, high electron mobility, high switching speed and low on-resistance. Here we report on the Ohmic contact resistance and reverse-bias characteristics of AlGaN/GaN Schottky barrier diodes with and without annealing. Annealing in oxygen at $500^{\circ}C$ resulted in an increase in the breakdown voltage from 641 to 1,172 V for devices with an anode-cathode separation of $20{\mu}m$. However, these annealing conditions also resulted in an increase in the contact resistance of $0.183{\Omega}-mm$, which is attributed to oxidation of the metal contacts. Auger electron spectroscopy revealed diffusion of oxygen and Au into the AlGaN and GaN layers following annealing. The improved reverse-bias characteristics following annealing in oxygen are attributed to passivation of dangling bonds and plasma damage due to interactions between oxygen and GaN/AlGaN. Thermal annealing is therefore useful during the fabrication of high-voltage GaN devices, but the effects on the Ohmic contact resistance should be considered.

• 대한조선학회지
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• 제26권2호
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• pp.1-12
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• 1989

본 논문에서는 선체로부터 멀리 전파해 나아가는 선형파와 선체 가까이에 존재하는 쇄파로 인한 조파저항성분을 최소화시키는 방법을 보여준다. 본 방법은 선형조파저항의 최적화 방법과 시험자료 분석을 통한 쇄파저항의 통계적 최적화방법으로 구성된다. 응용목적으로서, 수선형상이 포물선이고 측면이 수직한 모형을 기본선형으로 택하였고, 선형파를 최적화하는 방법과 경험적인 방법을 통하여서 선체전반부의 횡단면적 곡선을 변화시킨 두척의 수정모형선을 얻었다. 3척의 선형에 대한 시험 및 분석결과로부터 선체전반부의 횡단면적 곡선의 변화에 따른 선형파저항과 쇄파저항과의 상관관계를 살펴보았다. 본 방법으로 선체전반부가 최적화된 선형은 설계속도($F_n=0.26$)에서 기본선형에 비하여 약 47%의 조파저항감소를 보이고 있다.

• 한국지반공학회논문집
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• 제28권2호
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• pp.43-55
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• 2012

본 연구에서는 연약지반개량공법의 하나인 쇄석다짐말뚝공법의 저항계수를 산정하기 위한 저항편향계수를 산정하였다. 쇄석다짐말뚝공법의 저항편향계수를 산정하기 위하여 국내외 현장에서 수행된 41개 말뚝의 재하시험 결과로부터 산출된 2.54cm 침하량기준의 극한지지력과 말뚝직경의 2~3배의 깊이에서 팽창파괴가 지배적인 파괴유형이므로 팽창파괴에 대한 7개의 극한지지력공식을 사용하여 저향편향계수를 분석한 결과 확률밀도함수는 쇄석다짐말뚝의 7개 팽창파괴에 대한 극한지지력식 모두 로그정규분포 형태를 보였고, 저항편향계수/변동계수는 Greenwood(1970) 제안식에서는 0.91/0.38, Hughes & Withers(1974) 제안식에서는 1.19/0.39로 팽창파괴에 대한 극한지지력식 중에서 저항계수설계법의 저항계수 산정 시 적합한 제안식으로 분석되었다.

• 식물병연구
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• 제12권3호
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• pp.235-239
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• 2006

Since the cultivation of resistance cultivar is essential for organic agriculture, Phytophthora late blight resistance of 16 advanced potato clones obtained from the potato breeding laboratory at the National Institute of Highland Agriculture was evaluated. Resistance of the clone was examined through artificial inoculation in the laboratory and in the field. Dominant isolates of the pathogen in Gangwon province produced abundant sporangia on leaves of most clones showing susceptibility. The number of sporangia ranged from $10^{7{\sim}8}sporangia/ml$ in the susceptible clones at 7 days after inoculation. However, one clone is resistant in organic farming fields. Disease incidence was 2.3% using the resistant clone. The area under disease progress curve(AUDPC) was 75.5. Contrarily, disease incidence of the susceptible variety was 100% and the AUDPC was 1773.5 during the same cultivation period. The resistance clone named as 'Haryeong' is considered suitable for organic potato cultivation in Gangwon province in Korea.

• 한국연초학회지
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• 제20권1호
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• pp.66-70
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• 1998

TMV resistant lines (TRLs) originated from the Blo plant of Nicotiana tabacum cv. NC82 transformed with TMV coat protein cDNA which initially showed delayed disease symptom were selected for increased resistance in each subsequent generation. The result of field experiment of the transgenic tobacco lines in the fifth generation for TMV resistance and their response to other tobacco diseases (black shank, bacterial wilt, and powdery mildew) is described in this report. When fifteen TRLs of the fifth generation were tested for TMV resistance by mechanically inoculating the individual plants, over 95 percent of the plants of 6 lines showed complete resistance even 8 weeks after the inoculation. Average frequency of the resistant plants in TRLs of the fifth generation 8 weeks after the inoculation was 87%. Stable insertion and expression of TMV coat protein cDNA in the fifth generation of the transgenic tobacco plant were confirmed by PCR and immunoblot hybridization, respectively. All TRLs were resistant to the black shank but were susceptible to the bacterial wilt disease and the powdery mildew to the same degree as non-transgenic NC82 was. Therefore, it was indicated that the phenotypes related at least to disease resistance were not changed in the transgenic tobacco. Key words : TMV CP cDNA, TMV resistant tobacco plant, transformation.

• 한국도로학회논문집
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• 제19권6호
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• pp.129-137
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• 2017

PURPOSES : The purpose of this study is to develop bridge deck concrete materials based on ordinary Portland cement concrete, and to evaluate the applicability of the developed materials through material properties tests. METHODS : For field implementation, raw material (cement, fine aggregate, and coarse aggregate) properties, fresh concrete properties (slump and air content), strength (compressive, flexural and bond strength) gain, and durability (freeze-thaw resistance, scaling resistance, and rapid chloride penetrating resistance) performance were evaluated in the laboratory. RESULTS : For the selected binder content of $410kg/m^3$, W/B = 0.42, and S/a = 0.48, the following material performance results were obtained. Considering the capacity of the deck finisher, a minimum slump of 150 mm was required. At least 6 % of air content was obtained to resist freeze-thaw damage. In terms of strength, 51.28 MPa of compressive strength, 7.41 MPa of flexural strength, and 2.56 MPa of bond strength at 28 days after construction were obtained. A total of 94.9 % of the relative dynamic modulus of elasticity after 300 cycles of freeze-thaw resistance testing and $0.0056kg/m^2$ of weight loss in a scaling resistance test were measured. However, in a chloride ion penetration resistance test, the result of 3,356 Coulomb, which exceeds the threshold value of the standard specification (1000 Coulomb at 56 days) was observed. CONCLUSIONS : Instead of using high-performance modified bridge deck materials such as latex or silica fume, we developed an optimum mix design based on ordinary Portland cement concrete. A test construction was carried out at ramp bridge B (bridge length = 111 m) in Gim Jai City. Immediately after the concrete was poured, the curing compound was applied, and then wet mat curing was applied for 28 days. Considering the fact that cracks did not occur during the monitoring period, the applicability of the developed material is considered to be high.

• 상하수도학회지
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• 제30권1호
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• pp.1-8
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• 2016

Temperature correction trans-membrane pressure (TC-TMP) is frequently used as a fouling index in membrane water treatment plants. TC-TMP equation is derived based on an assumption that the total membrane resistance (i.e. the sum of the intrinsic membrane resistance and fouling resistance) is not affected by temperature. This work verified the validity of this assumption using microfiltration (MF) and ultrafiltration (UF) membranes with and without fouling. The foulants used in the work were kaolin (inorganic) and humic acid (organic). The intrinsic resistances of MF and UF membranes remains at constant values regardless of temperature change. When the same amount of foulants were accumulated on the membrane, inorganic fouling resistance with kaolin was constant regardless of temperature change while organic fouling resistance with humic acid decreased at higher temperatures, which means that TC-TMP cannot be used as a fouling index when organic fouling occurs in a real field application. Since TC-TMP underestimates the amount of fouling at higher temperatures, more attention should be necessary in the operation of membrane water treatment plant in a hotter season like summer.

• 한국동물위생학회지
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• 제34권3호
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• pp.217-226
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• 2011

Salmonella spp. is of increasing public health concern as causative pathogens of food poisoning. The aim of this study was to investigate the serotypes and antimicrobial resistance pattern of Salmonella spp. isolated from duck farms in Daegu-Gyeongbuk province. Also, S. Enteritidis and S. Typhimurium isolates were further examined for plasmid analysis, phage typing and pulsed-field gel electrophoresis (PFGE). A total of 34 Salmonella spp. (16.4%) were isolated from duck farms and ten serotypes were identified. The predominant serotypes were S. Typhimurium (23.5%) S. Fyris (17.6%) and S. Haardt (11.8%), S. Agona and S. Enteritidis (respectively 8.8%). Of 34 Salmonella isolates, 15 (44.1%) isolates were resistant to at least one antimicrobial agent and multiple resistance (resistance to more than 4 drugs) was observed in 9 strains (26.5%). The high resistance was found to streptomycin (32.4%), tetracycline (29.4%), ampicillin, kanamycin and nalidixic acid (respectively, 26.5%), all Salmonella isolates were susceptible to cefoxitin, cefotaxime, gentamicin, amikacin and ciprofloxacin. All S. Enteritidis and S. Typhimurium isolates were found to contain only one plasmid (ca. 54 or 55kb, respectively). Among the S. Enteritidis isolates, two phage types were found, PT32a and PT1c, respectively, one isolates did not react with any of the phages used. Whereas, all S. Typhimurium isolates were RDNC (reacts but does not conform). PFGE showed to be a useful typing method better than plasmid analysis and phage typing for discrimination of isolates especially, S. Typhimurium isolates. Our results indicated that the serotypes of Salmonella isolates are widely distributed in duck farms, further epidemiological studies should be carried out.