• Biomolecules & Therapeutics
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• 제24권1호
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• pp.1-8
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• 2016

Alpha-ketoglutarate (AKG) is a key molecule in the Krebs cycle determining the overall rate of the citric acid cycle of the organism. It is a nitrogen scavenger and a source of glutamate and glutamine that stimulates protein synthesis and inhibits protein degradation in muscles. AKG as a precursor of glutamate and glutamine is a central metabolic fuel for cells of the gastrointestinal tract as well. AKG can decrease protein catabolism and increase protein synthesis to enhance bone tissue formation in the skeletal muscles and can be used in clinical applications. In addition to these health benefits, a recent study has shown that AKG can extend the lifespan of adult Caenorhabditis elegans by inhibiting ATP synthase and TOR. AKG not only extends lifespan, but also delays age-related disease. In this review, we will summarize the advances in AKG research field, in the content of its physiological functions and applications.

• 천문학회보
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• 제43권2호
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• pp.36.2-36.2
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• 2018

Cosmic reionization era in the early universe was playing a leading part on making the present universe we know. However, we have not been able to reveal the main contributor to the cosmic reionization to date. Faint quasars have been mentioned as the alternative due to the uncertainty of the faint end slope of the quasars luminosity function. With the availability of the deep (~25mag) images from Subaru Hyper Suprime-Cam (HSC) Strategic Program survey, we have tried to find more quasar with low luminosity in the ELAIS-N1 field. Faint quasar candidates were selected from several multi-band color cut criteria based on the track of the simulated quasar at z ~ 5. The Infrared Medium-deep Survey (IMS) and The UKIRT Infrared Deep Sky Survey (UKIDSS) - Deep Extragalactic Survey (DXS) provide J band information which is used to cover the relatively long wavelength range of quasar spectra. To search the reliable candidates with possible Lyman break, medium-band observation was performed by the SED camera for QUasars in EArly uNiverse(SQUEAN) in the McDonald observatory and Seoul National University 4k Camera(SNUCAM) in the Maidanak observatory. Photometric redshifts of the observed candidates were estimated from chi-square minimization. Also, we predicted the importance of the faint quasar to the cosmic reionization from the expected number density of the faint quasar.

• 지구물리와물리탐사
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• 제2권1호
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• pp.43-53
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• 1999

전자탐사 수치모델링 및 역산은 복잡한 지하구조에 대한 전자기장의 정확한 거동양상 규명을 위한 기본적인 해석방법이다. 본 연구에서는 2.5차원 전자탐사 수치모델링 알고리즘을 유한요소법을 이용하여 구하였다. 이때 전기장과 자기장이 결합되어 표현되는 2.5차원 미분방정식을 정식화할 때 선형적 물성변화를 고려하는 유한요소 방정식을 도출, 제의하였다. 송신원의 영향이 큰 근거리장과 균질 반무한공간의 반응이 지배적인 원거리장 각각에 대하여 모델변수를 검토하고 이를 토대로 균질 반무한공간에서의 해석적인 해와 비교하여 봄으로써 알고리즘의 타당성을 검증하였다. 본 연구에서 제시한 수치 모형반응 알고리즘에 부합하는 수정된 블록역산모형을 고안하였으며 고립형 이상체에 대한 분해능을 살펴봄으로써 분산방정식으로 표현되는 전자탐사자료의 역해 가능성 및 한계를 고찰하였다.

• 한국간호교육학회지
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• 제25권1호
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• pp.69-82
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• 2019

Purpose: The purpose of the study is to understand the experiences of career exploration among nursing students during their clinical practice and to develop a theoretical framework for the career exploration process. Methods: From February 2 to 28, 2015, data were collected through focus group interviews from 24 participating fourth-year nursing students. The data were analyzed using grounded theory. Results: The central phenomenon of 'confusion between the ideal and the reality of nursing' occurred in contexts for various reasons of choosing one's major, nurses in the ideal, a vague fear of the field, arduous nursing assignments in the field, and severe adversity in the nursing field. Nursing students tried to deal with their confusion by using interaction strategies such as pursuing the intrinsic value of nursing, finding role models, trying to project oneself, and preparing for adapting to reality. The career exploration process in clinical practice was a voyage to discover the authentic nurse of the pre-registration nurse. Conclusion: This result shows that nursing students were to gain confidence in their career choices by finding the value of nursing and interacting with patients. Therefore, opportunities for learning experiences about interaction with patients and various positive experiences in clinical practice should be provided for nursing students.

• 한국컴퓨터정보학회논문지
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• 제25권12호
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• pp.173-186
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• 2020

본 논문에서는 지하공간 통합지도를 탐사 현장에서 활용하기 위한 모바일 단말기용 서비스 시스템을 설계 구현한다. 모바일 단말기용 현장활용 서비스 시스템은 지하공간 통합지도 관리 시스템에서 제공하는 타일맵, 3차원 지형정보, 지하구조물, 지하시설물, 지반정보 등을 현재 위치에 따라 3차원으로 가시화하도록 설계되었고, 현장 탐사로 얻어진 결과를 실시간으로 반영하도록 설계되었다. 또한, 제안된 시스템은 모바일 단말기의 무선 네트워크 및 기기 특성에 따른 제약 문제로 지하공간 통합지도를 glTF 포맷 형태로 전송 후 가시화 하도록 구현하였다. 구현된 모바일 서비스 시스템은 지하공간 탐사 현장에서 3차원으로 지도 및 공간 객체들을 가시화하여 사용자에게 정확하고 통합된 지하공간 데이터를 제공함으로써 탐사 현장에서의 사고 발생을 방지할 수 있다. 그리고, 갱신된 지하공간 데이터를 실시간으로 지하공간 통합지도 관리 시스템에 전송하여 최신성과 정확성을 유지할 수 있다.

• 한국환경과학회지
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• 제19권3호
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• pp.343-351
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• 2010

Since the effect of environmental education at class using textbooks or materials related to environment is limited, the importance of activities for field experience is getting increased day by day. Thereby, the education tends to change into the type of education providing students with direct environmental experience. Students attending the science high school have excellent aptitude and ability for science and will lead the development of science in the future. Now it is urgent to develop various experiential programs which are helpful for them to establish desirable values on environment. However, the field of environmental education that allows science high school students equipped with ample environmental knowledge to improve environment sensitivity and have proper environment awareness is quite restricted as of now. Natural exploration activities are the programs which provide science high school students having lack of chance for environmental education with good opportunities to contact nature and also play significant roles in arousing their interest in issues related with environment. Therefore, it is thought that they will let science high school students explore the natural features of Korea, understand the importance of preserving environment and ecosystem profoundly, and encourage environmental awareness and will of environmental practice. Thereupon, with the study subjects of 121 first and second graders at U Science High School, this article analyzed their recognition of the necessity for environmental education and environmental pollution problems before and after the natural exploration activities, and conducted a survey on their satisfaction after the natural exploration activities and analyzed it. The result of this research is as follows. First, it was shown that the natural exploration activities were effective to raise the science high school students' awareness of issues related with environmental pollution. Second, the natural exploration activities had effect upon enhancing the students' willingness of environmental practice. Third, there was statistically significant correlation between the science high school students' satisfaction with the natural exploration activities and their achievement in the science subject. Fourth, there also was a statistically non or weakness significant correlation between their satisfaction with the natural exploration activities and preference for the science subject. In particular, it was found that students preferring biology indicated higher satisfaction.

• 한국지구물리탐사학회:학술대회논문집
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• 한국지구물리탐사학회 2007년도 공동학술대회 논문집
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• pp.313-316
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• 2007

Ground-penetrating radar (GPR) is an effectiveness tool for imaging spatial distribution of hydrogeologic parameters. An artificial groundwater recharge test has been conducted in Nagaoka City in Japan, and time-lapse crosshole GPR data were collected to monitor infiltration processes in a vadose zone. Since radiowave velocities in a vadose zone are largely controlled by variations in water content, the increase in traveltimes is interpreted as an increase in saturation in the test zone. We use a finite-difference time-domain method in two-dimensional cylindrical coordinates to simulate field results. Numerical modeling successfully reproduces the major feature of velocity changes in the filtration process.

• 항공우주시스템공학회지
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• 제9권4호
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• pp.73-80
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• 2015

For Korean first lunar exploration program, KARI(Korea Aerospace Research Institute) has been researching in various fields and investigating cases of abroad lunar exploration spacecrafts. In the field of the flight software, KARI has been analysing some cases such as NASA LRO, and this paper describes the result of the case study on LRO flight software.

• 천문학회보
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• 제43권2호
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• pp.36.1-36.1
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• 2018

Star formation activity of galaxies, along with color and morphology, show significant environmental dependence in local universe, where galaxies in dense environment tend to be more quiescent and redder. However, many studies show that such environmental dependence does not continue at higher redshifts beyond z~1. The question of how the environmental dependence of galactic properties have developed over time is crucial to understanding cosmic galactic evolution. By combining data from Canada-France-Hawaii Telescope Legacy Survey(CFHTLS), Infrared Medium-Deep Survey(IMS), and other surveys, the photometric redshifts of galaxies in CFHTLS W2 field were estimated by fitting spectral energy distribution. The distribution of galaxies was mapped in redshift bins of 0.05 interval from 0.6 to 1.4. For each redshift bin, the number density was mapped. The galaxies in high density regions were grouped into clusters using friend-of-friend method. The color of galaxies were analyzed to study the correlation with redshift as well as environmental difference between field galaxies and cluster member galaxies.

• 천문학회보
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• 제42권1호
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• pp.34.2-34.2
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• 2017

A small wide-field imaging telescope is a powerful instrument to survey the Universe: wide-field image can monitor the variability of many sources at a time, e.g. young stellar objects and active galactic nuclei, and it can be an effective way to locate transient sources without precise positional information such as gravitational wave sources or some gamma-ray bursts. In February 2017, we installed a 0.25 m f/3.6 telescope on the McDonald 0.8 m telescope as a piggyback system. With a $4k{\times}4k$ CCD camera, the telescope has a $2.35{\times}2.35deg$ field-of-view. Currently, it is equipped with Johnson UBVRI filters and 3 narrow-band filters: $H{\alpha}$, OIII and SII. We will present the installation process, and the telescope performance such as detection limit and image quality based on the data from commissioning observations. We will also discuss possible scientific projects with this system.