• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제37권2호
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• pp.127-132
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• 2011

Juvenile ossifying fibroma is an expansive intraosseous lesion of the bones. In most patients, the tumors are located in the facial bones. The main characteristics of juvenile ossifying fibroma are the early age of onset, localization of the tumor, radiological pattern and a tendency for recurrence. This article describes a case of expanded juvenile ossifying fibroma in the right maxilla in a 12-year old boy. The lesion was removed totally by surgery under general anesthesia. The patient showed no radiological signals of recurrence approximately two years after surgery.

• Journal of Korean Neurosurgical Society
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• 제29권4호
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• pp.559-563
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• 2000

Cementifyng fibroma is one of the fibro-osseous lesions. All fibro-osseous lesions containing cementum are considered to be of periodontal membrance origin and is most common in the maxilla and mandible. Rarely, cementifying fibromas are seen in other craniofacial bone except jaw lesion. A diligent search in the available world literature show only two documentation of cementifying fibroma in the fronto-orbital bone. This case is third case but first in the frontal bone beyond orbit. The authors report a case of cementifying fibroma of the frontal bone in 12-year-old female patient.

• 치과방사선
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• 제21권2호
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• pp.261-273
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• 1991

This study was undertaken to document and better defined this condition to help clarify this clinical and radiographical appearances by the analysis of clinical and radiographical features of fibro-osseous lesions in the jaws. A study was made of a series of 128 cases with fibro-osseous lesions. The obtained results were as follows. 1. Fibrous dysplasia of the jaws occurred with equal predilection for males and females. But the females occurred in 68% of cemento-ossifying fibroma and 75% of periapical cemental dysplasia. 2. 43% of fibrous dysplasia and 32% of cemento-ossifying fibroma occurred in the 2nd decades and 33% of periapical cemental dysplasia in 5th decades. 3. 62% of fibrous dysplasia occurred in the maxilla, 73% of cemento-ossifying fibroma in mandible, 90% of periapical cemental dysplasia in mandible. 4. 98% of fibrous dysplasia occurred in premolar-molar region, 77% of cemento-ossifying fibroma in molar region, 68% of periapical cemental dysplasia in incisor region. 5. In serial radiographic features, mature stage were 55% of fibrous dysplasia, 45% of cemento-ossifying fibroma, 59% of periapical cemental dysplasia. 6. 87% of fibrous dysplasia had monostotic lesion, 67% of periapical cemental dysplasia had multiple lesions. 7. In fibrous dysplasia and cemento-ossifying fibroma, migration of tooth occurred in 61.7% and 36.4%, retention of tooth occurred in 4.3% and 9.1%, loss of lamina dura occurred in 6.4% and 9.1%, and root resorption had not occurred in fibrous dysplasia, but occurred in 18% of cemento-ossifying fibroma, displacement of mandibular canal occurred in 14.9% and 31.8%.

• 대한바이러스학회지
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• 제28권4호
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• pp.369-375
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• 1998

In our preliminary study to find antiviral or antitumor agents from Korean natural products, we found that the Shope fibroma virus (SFV) induced fibromas reaching maximum size at $5{\sim}6$ days with spontaneous disappearance at $15{\sim}20$ days after SFV intracutaneous inoculation into Korean domestic rabbits. However, the sizes of fibromas of rabbits at day 5 after virus inoculation were significantly different individually. Assuming that the variation of tumor size was due to either susceptibility or the preexisting antibodies against SFV in the Korean domestic rabbits, the rabbits were checked for the antibodies against SFV by IFAT using SFV infected RK13 cells. The antibody positive rate of normal Korean domestic rabbits was 32.8% and the sizes of the fibromas of the positive rabbits were significantly smaller than those of negative rabbits (p<0.0001). The fibroma sizes were dependent on the antibody titers of rabbits to SFV. The sizes of fibromas after inoculation of SFV into immunized rabbits were about one tenth of those by the first inoculation into normal rabbits. This is the first report on the antibody prevalence against SFV among normal Korean domestic rabbits and it suggest the existence of a wild fibroma virus or related virus in Korea.

• 대한골관절종양학회지
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• 제13권2호
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• pp.162-166
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• 2007

결합조직형성 섬유종은 조직 소견상 연부 조직의 유건종(desmoid tumor)과 유사한, 비교적 드문 종양으로 대부분 장관골에 발생한다. 그러나 양성 종양이지만 골소파 및 골이식 치료후에는 국소 재발이 빈번한 것으로 알려져 있다. 더욱이 재발을 하게 되면, 아주 드물지만 골 육종으로 악성 변화되는 경우가 보고되고 있다. 본 교실에서는 17세 남자 환자에서 근위 경골에 발생한 결합 조직 섬유종에 대해 소파술 및 골 이식술을 시행 후, 11년 후에 골육종으로 악성 변화된 결합조직형성 섬유종 1례를 경험하였기에 보고하는 바이다.

• 치과방사선
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• 제16권1호
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• pp.113-126
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• 1986

This study was undertaken to document and better define this condition to help clarify this clinical and radiographic appearances by the analysis of clinical and radiographic features of cementoma. A study was made of a series of 104 cases with cementoma. This investigation of cementoma revealed the following features: 1. The female occurred in 73% of periapical cemental dysplasia and benign cementoblastoma, and 80% of cementifying fibroma. 2. 40% of periapical cemental dysplasia occurred in the fifth decades, and 73% of benign cementoblastoma during the second and third decades, while there was no age predilection in the cementifying fibroma. 3. 63% of periapical cemental dysplasia occurred in the mandibular anterior region. 91% of benign cementoblastoma and 80% of cementifying fibroma occurred in the mandibular premolar and/or molar region. 4. There were no cases complaining the associated clinical signs and subjective symptoms in the periapical cemental dysplasia, however the patient complained the pain in 36% of benign cementoblastoma and 40% of cementifying fibroma. 5. There were no cases expanding the cortical plates in the periapical cemental dysplasia, however 73% of benign cementoblastoma and all of 5 cases of cementifying fibroma showed the expansion of cortical plates. 6. Several radiographic features of the periapical cemental dysplasia were shown: a. 29% of the cases had multiple lesions. b. 53% of the cases were in the mature stage. c. During the osteolytic stage, the alveolar lamina dura was lost in 89% of the cases.

• 대한골관절종양학회지
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• 제6권2호
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• pp.92-97
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• 2000

결합조직형성 섬유종은 골에 발생하는 종양중 매우 드문 종양으로, 조직학적으로나 생물학적 성상이 연부조직에 발생하는 복강외 섬유종과 유사하다. 저자들은 22세 남자에 발생한 견갑골 병변과, 34세 남자에 발생한 치골병변을 보고하는 바이다. 방사선학적으로 종양은 골융해성 병변으로, 팽창성 성장을 하였다. 조직학적으로, 다량의 교원질 섬유를 함유하고 있는 방추형 세포로 구성되어 있다. 광범위 절제술을 시행하였으며, 재발은 없었다. 골에 원발성으로 발생하는 결합조직형성 섬유종은 매우 드문 골 종양으로 참고문헌과 함께 보고하는 바이다.

• 대한골관절종양학회지
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• 제9권1호
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• pp.110-114
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• 2003

연골 유점액 섬유종은 젊은 층에서 발생하며 비교적 드문 양성종양이나 재발률이 높은 것으로 알려져 있다. 경골의 근위 1/3의 골간단에 대부분 발생하며 족부에도 20%에서 발생한다고 보고하였다. 저자는 족부에 발생한 연골 유점액 섬유종 1례에 대하여 1차 소파술 및 골 이식술을 시행하였으며 술 후 7개월에 재발하여 전절제술 및 장골 이식술을 시행하여 24개월간 추시 후 만족스러운 결과를 얻었다.

• Journal of Chest Surgery
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• 제28권5호
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• pp.491-494
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• 1995

A fibroma arising in the right ventricle outflow tract of a 14 month-old infant was successfully removed. The patient was first seen because of shortness of breath and tachycardia. Pertinent clinical and laboratory findings included a grade II/VI systolic murmur, blood pressure of 120/60 mmHg, slight cardiomegaly on chest X-ray, a mass obstructing the outflow tract of the right ventricle on echocardiography and magnetic resonance imaging. On october 30,1992, under cardiopulmonary bypass, a 4cm x 3cm x 3cm tumor was resected from the right ventricular outflow tract, together with a portion of the ventricular wall. Histologically, it was diagnosis as a fibroma. The patient was sent home on the 6th postoperative day following an uneventful recovery form the operation. Although cardiac fibroma is the second most common cardiac tumor in infancy and childhood, it is usually found in the left ventricle and one arising in the right ventricle is considered rare. Although it is a benign tumor, it could produce a severe cardiac dysfunction and even sudden death, depending on its size and location. With the advance in diagnostic techniques and operative management, there is a renewed interest in the early detection and operative removal of these tumors. The case herein presented is the first such case successfully managed and reported in the Korean literature.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제41권1호
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• pp.48-51
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• 2015

Cemento-ossifying fibromas are benign tumors, and, although cases of an aggressive type have been reported, no cases of cemento-ossifying fibroma transforming into osteosarcoma have been documented previously. Low-grade osteosarcoma is a rare type of primary bone tumor, representing 1%-2% of all osteosarcomas. A 45-year-old female patient was diagnosed with cemento-ossifying fibroma, treated with mass excision several times over a period of two years and eight months, and followed up. After biopsy gathered because of signs of recurrence, she was diagnosed with low-grade osteosarcoma. The patient underwent wide excision, segmental mandibulectomy, and reconstruction with fibula free flap. The aim of this report is to raise awareness of the possibility that cemento-ossifying fibroma can transform into osteosarcoma and of the consequent necessity for careful diagnosis and treatment planning.