• 한방비만학회지
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• 제9권2호
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• pp.65-73
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• 2009

Objectives This study was to report the effect of oriental medical treatment and dietetic therapy on metabolic syndrome. Method We treated three cases of metabolic syndrome patients with herbal medicine, electroacupuncture, cupping a boil, dietetic therapy, aerobic exercise were done during the treatment period. Result After treatment the diagnostic index(waist circumference, triglycerides, HDL cholesterol, blood pressure, fasting glucose) was improved. Conclusion The patient with Metabolic syndrome was improved using oriental medical treatment and dietetic therapy.

• Journal of Chest Surgery
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• 제51권1호
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• pp.76-80
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• 2018

Early diagnosis followed by primary repair is the best treatment for spontaneous esophageal perforation. However, the appropriate management of esophageal leakage after surgical repair is still controversial. Recently, the successful adaptation of vacuum-assisted closure therapy, which is well established for the treatment of chronic surface wounds, has been demonstrated for esophageal perforation or leakage. Conservative treatment methods require long-term fasting with total parenteral nutrition or enteral feeding through invasive procedures, such as percutaneous endoscopic gastrostomy or a feeding jejunostomy. We report 2 cases of esophageal leakage after primary repair treated by endoscopic vacuum therapy with continuous enteral feeding using a Sengstaken-Blakemore tube.

• 대한의생명과학회지
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• 제17권4호
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• pp.337-345
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• 2011

It is well recognized that conventional coronary artery bypass grafting (ONCAB) often leads to major organ dysfunction including renal injury. Diabetes mellitus is a major cause of nephropathy and poor clinical outcomes. The aim of this retrospective study was to evaluate the occurrence of adverse outcomes including renal impairment between diabetic (n=75, DM group) and non-diabetic patients (n=72, Non-DM group) underwent off-pump coronary artery bypass grafting surgery (OPCAB). Fasting glucose, hemoglobin A1c, fructosamine, fibrinogen and serum osmolality levels in the DM group were higher than those of the Non-DM group at pre-operative (Pre-OP) period ($P$ <0.05). History of hypertension and renal impairment in the DM group was higher than that of the Non-DM group ($P$ <0.05). Potassium ($K^+$), blood urea nitrogen and creatinine levels were higher, whereas sodium ($Na^+$) and glomerular filtration rate (GFR) levels were lower in the DM group than the Non-DM group at peri-operative period ($P$ <0.05). Fasting glucose levels at Pre-OP period had positive correlations with blood urea nitrogen and creatinine levels at peri-operative period, but negative correlations with GFR levels at peri-operative period in the DM group ($P$ <0.05). Incidences of renal impairment, diuretic therapy or continuous renal replacement therapy and fever in the DM group were higher than those of the Non-DM group at post-operative period ($P$ <0.05). These results suggest that blood glucose level should be tightly controlled at peri-operative period to avoid renal dysfunction in diabetic patients.

• Nutrition Research and Practice
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• 제10권3호
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• pp.328-335
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• 2016

BACKGROUND/OBJECTIVES: Vitamin D plays an important role in the etiology of gestational diabetes mellitus (GDM). This study evaluated the effect of vitamin D supplementation on metabolic indices and hs-C-reactive protein (CRP) levels in GDM patients. SUBJECTS/METHODS: The study was a randomized, placebo-controlled, double-blinded clinical trial. Seventy-six pregnant women with GDM and gestational age between 24-28 weeks were assigned to receive four oral treatments consisting of 50,000 IU of vitamin $D_3$ (n = 38) or placebo (n = 38) once every 2 weeks for 2 months. Fasting blood glucose (FG), insulin, HbA1c, 25-hydroxyvitamin D, lipid profile, hs-CRP, and homeostasis model assessment-insulin resistance (HOMA-IR) were measured before and after treatment. Independent and paired t-tests were used to determine intra- and intergroup differences, respectively. ANCOVA was used to assess the effects of vitamin D supplementation on biochemical parameters. RESULTS: Compared with the placebo group, in the vitamin D group, the serum level of 25-hydroxyvitamin D increased (19.15 vs. -0.40 ng/ml; P < 0.01) and that of FG (-4.72 vs. 5.27 mg/dl; P = 0.01) as well as HbA1c (-0.18% vs. 0.17%; P = 0.02) decreased. Improvements in the lipid profiles were observed in the vitamin D group, but without statistical significance. Significant increases in concentrations of hs-CRP, FG, HbA1c, total cholesterol, and LDL cholesterol were observed in the placebo group. No significant change in fasting insulin and HOMA-IR was observed in either group. CONCLUSIONS: In GDM patients, vitamin D supplementation improved FG and HbA1c but had no significant effects on lipid profile or hs-CRP.

• Journal of Nutrition and Health
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• 제27권2호
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• pp.172-180
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• 1994

This study showed the psychological symptoms, nutritional status and eating behaviors of diabetic patients. General informations on subjects nutritional status were collected by questionnaire, whereas Symptom Check List-90-Revision(SCL-90R) was used for gathering the data related to psychological problem. 34 diabetics in the hospital, aged 49$\pm$10.5 years old, were chosen as the subjects of this study. Their average height was 162.3$\pm$9.4cm and weight was 57.0$\pm$9.5kg. The average period of their suffering from DM was 54.1 weeks. Among, the subjects, 71.0% adapted diet therapy for their disease, whereas 36.7% and 40.7% did diabetic drugs and daily exercise like walking and jogging, respectively, Among 9 psychological symptoms observed, the scores of somatization, depression, anxiety, phobic anxiety and psychoticism were higher than the standard score, however they were not statistically significant. The score of paranoid ideation was lower than standard score. It was statistically significant. As the measure of their clinical status, BMI(body mass index), PIBW(percent ideal body weight) and fasting blood sugar(FBS) were selected 21.6$\pm$2.8, 102.4$\pm$14.8% and 207.8$\pm$19.9mg/이 respectively. The somatization was significantly correlated with subjects duration of DM. Subjects with psychological problems showed wrong eating behaviors. The fasting blood sugar was significantly correlated with the level of depression.

• 동의생리병리학회지
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• 제26권2호
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• pp.212-220
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• 2012

In this study, we tried a study on a direction of the field of oriental medicine on accepting complementary alternative medicine by analyzing the related thesis, journals and papers on the complementary alternative medicine published in the field of oriental medicine. As the result of analyzing the present study of the field of oriental medicine on the complementary alternative medicine, there have been 22 studies on the complementary alternative medicine. Thesis, papers were mainly experimental papers about the bee venom therapy, energy therapy, fasting therapy, and colon therapy, and the journals were actively studied in order of clinical paper, experimental paper, and reference paper about the bee venom therapy, energy therapy, and reflexolgy. The acceptance of complementary alternative medicine by the field of oriental medicine through a scientific relation should be conducted more systemically by setting the main academy taking charge of the study on common characteristics of the complementary alternative medicines on the classification of NCCAM as well as the related academies taking charge of the study on the unique characteristic of each complementary alternative medicine. First, additional studies are needed to make the most of characteristics of each complementary alternative medicine through the main academy and the related academies, and for the next, additional studies are necessary to complement the research trend on each complementary alternative medicine through the main academy and related academies.

• 동아시아식생활학회지
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• 제10권1호
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• pp.21-36
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• 2000

The purpose of this study was to investigate the effect of knowledge and practice of diet therapy on diabetic control in Insulin-dependent Diabetics. The subjects were 31 patients (male 15, female 16) aged 7 to 16 years old who participated pediatric health camp. The average of diabetic of diabetic duration was4.2 years. 48.4 % of subjects has the motive to diabetics diagnosis because of 3-plentiful symptom in both group. The average of height was 151.5 cm for male and 141.4cm for female, the average weight was 43.1 kg for male and 38.6kg for female. In PIBW, underweight was 53.3 % for male, 37.5% for female, normal weight was 40.0% for male, 56.3% for female. The fasting blood glucose was 173.5mg/dl males, 202.9mg/dl for females, Postprandial blood glucose was 138.8mg/dl for males, 194.3mg/dl for females. Energy intakes were 2,100 -2.600 kcal for males and 1,800-2,600kcal for females. Energy intake of the subjects was higher than that of RDA. Carbohydrate, protein and fat ratio was 58 : 17: 25. The mean score of knowledge before education on diet therapy was 17.07$\pm$2.02 for males, 15.19$\pm$3.58 for females. The mean score of knowledge after education on diet therapy was 17.93$\pm$1.33 for males , 17.31 $\pm$1.49 for females.

• The Korean Journal of Physiology
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• 제10권1호
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• pp.67-71
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• 1976

Effect of Electro Convulsion Therapy (ECT) on the Human Growth Hormone (HGH) response was observed in 32 cases of various mental illness. The patients were fasting overnight and ECT was induced in the morning by application of $90{\sim}120V$ for a period of $0.1{\sim}0.5\;sec$. In all patients, venous blood samples were taken prior to simultaneously with 1 and 4 hours after the ECT. Plasma was immediately seperated and stored in $-20^{\circ}C$ refrigerator. HGH concentrantion was determined by means of radioimmunoassay Results were as follows: 1. Application of electric current was not followed by a significant change in mean plasma HGH of 52 cases. 2 Increases of plasma HGH following ECT were observed in about half cases showing low initial level but in 20 other cases with high initial level of plasma HGH, reasonable decreases after therapy were not found. 3. Plasma concentration of HGH one hour after application of current were always higher than just after the current. 4. There were no differences between HGH responses to a 1st, 2nd or 5th ECT. 5. Discussions were made on the possible modification of HGH response following ECT by the autoregulatory control mechanism.

• 대한지역사회영양학회지
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• 제13권2호
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• pp.276-287
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• 2008

Diabetic mellitus in an older population is associated with increased basal oxidative stress and free radical accentuated by hyperglycemic challenge. Enhanced free radical in diabetic elderly can cause the oxidative damage and such damage can be protected by antioxidant defense system. It is believed that vitamin C, A and E are the most abundant and effective antioxidants in human plasma. The purpose of this study was to determine the antioxidant status in Korean diabetic elderly using the case-control study. The antioxidant status was examined by determining plasma levels of antioxidant vitamins (vitamin C, A, E, ${\beta}$-carotene), total antioxidant status (TAS) and thiobarbituric acid reactive substance (TBARS) and intakes of vitamin C, A, ${\beta}$-carotene and retiol. Fasting glucose and HbA1c levels and serum lipid profiles (triglyceride (TG), total cholesterol, HDL-cholesterol and LDL-cholesterol) were also determined. Diabetic subjects were 122 elderly persons over 60 years old, visiting public health center, and control subjects were 96 healthy elderly persons living in Ulsan, Korea and they were matched by age, gender, smoking and drinking status. The diabetic and control subjects were divided into sub-groups according to the status of using diet therapy and vitamin supplement. The subjects were interviewed to collect data on their general characteristics, disease history, vitamin supplement, diet therapy and health-related habits by questionnaires. Their dietary intakes were obtained by means of semi-quantitative food frequency questionnaires (SQFFQ). Fasting plasma glucose and HbA1c levels were significantly higher in diabetes than in control subjects, and plasma total cholesterol level of diabetes was not significantly different from that of control subjects. However serum HDL cholesterol level of diabetes was significantly lower and serum TG level of diabetes was significantly higher than those of control group. The average vitamin A and ${\beta}$-carotene intakes of diabetes were significantly higher than those of control subjects. There was no significant difference in plasma vitamin C, ${\beta}$-carotene, and TBARS levels between two groups, but plasma vitamin A, E and TAS levels were significantly higher in diabetes than those in control group. Plasma vitamin A and TAS levels of diabetic subjects using diet therapy were higher than those of control using diet therapy, and plasma vitamin E, ${\beta}$-carotene and TAS levels of diabetic subjects using vitamin supplements were significantly higher than those of controls using vitamin supplements. These results suggested that diabetic mellitus could enhance antioxidant defences against reactive oxygen species and interest in healthy eating such as consumption of more antioxidant nutrients.

• 대한영양사협회학술지
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• 제15권2호
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• pp.188-196
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• 2009

The purpose of this study was to investigate the effects of nutrition counseling on diabetes management by determining changes in anthropometry and blood components as well as knowledge and practice of diet therapy and nutrient intake in 34 (male 11, female 23) type 2 diabetes patients. The knowledge and the practice of diet therapy, drinking, smoking and exercise were analyzed by questionnaires. Dietary nutrient intake were obtained from the patients by the 1 day 24-hr recall. Blood glucose level and blood pressure were measured before and 3 months after the treatment. The results are summarized as follows: Average weight (p<0.05) and body mass index (p<0.05) were significantly lower post-counseling. Fasting blood glucose levels (p<0.01) and postprandial-2hour blood glucose levels (p<0.01) were also significantly lower post-counseling. In lifestyle changes for self-management the patients showed significantly higher exercise habits post-counseling (p<0.01). Regarding their level of diet knowledge, they showed significantly higher levels post-counseling in six items such as importance of diet therapy for diabetes (p<0.001), principles of diet therapy (p<0.001), nutrient composition of foods (p<0.01), carbohydrate composition of foods (p<0.001), the prescribed calories (p<0.001) understanding food item and exchange units of cereals, grains (p<0.001) and fruits, juices (p<0.001). Regarding their diet practices, the patients showed significantly higher levels of practice post-counseling in keeping within permitted meal size (p<0.001), using food exchange lists (p<0.001), keeping exact meal times (p<0.01), and controling sweet foods (p<0.001). Protein (p<0.05), animal lipid (p<0.05), and vitamin C (p<0.05) intakes were significantly higher post-counseling.