• Korean Journal of Clinical Pharmacy
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• v.8 no.2
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• pp.143-146
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• 1998

Acetaminophen (APAP) suppositories with active ingredients, i.e., polyethylene glycol (PEG), Witepsol H-15 (WH), were prepared for hospital use and investigated on their drug release characteristics and pharmacokinetics. WH was employed as oil-soluble base with an aim of reducing fragility and mucosa irritancy that are common drawbacks found in PEG suppositories. Also hollow type suppository was tried as compared with conventional type suppository. Drug release tests revealed that in most formulations, more than $80\%$ of loaded APAP were released within 20 minutes, except for APAP-WH hollow type suppositories. Significant differences in the plasma concentration profile were observed among four type suppositories. $T_{max}$ of APAP-PEG and APAP-WH suppositories were 90 and 60 minutes, respectively, in hollow types. APAP-WH hollow type suppositories demonstrated fast absorption rates of APAP as compared with those of APAP-PEG suppositories. No burst effect was observed from APAP-WH suppository in contrast to APAP conventional type suppository, whereas AUCs of all the suppositories were similar. APAP-WH hollow type suppository may be an useful dosage form for hospital use.

• 한국연소학회:학술대회논문집
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• 2002.11a
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• pp.173-184
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• 2002

In order to evaluate the devolatilization models of pulverized coal, various devolatilization models are examined for the numerical analysis of Drop Tube Furnace.The results of analysis are compared with the experimental results. A numerical study was conducted to explore the sensitivities of the predictions to variation of the model parameters. It helps to elucidate the source of the discrepancies. Three different wall temperature conditions of the DTF, 1100, 1300 and $1500^{\circ}C$ were considered in this analysis. Two fuels are U.S.A. Alaska coal and Australia Drayton coal. The results of analysis with constant rate model, single kinetic rate model and two competing rate modes well presented fast volatile matter release in the early devolatilization. However, in the latter devolatilization they did not coincide with experimental results which presented tardy volatile matter release on account of pyrolysis of high molecular substance. On the other hand, the results of analysis with DAEM(Distribute Activation Energy Model) coincided with experiment al results in overall devolatilization.

• Archives of Pharmacal Research
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• v.18 no.1
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• pp.18-21
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• 1995

Poly(ethylene glycol)(PEG) macrocers teminated with acrylate groups and semi-interpenetrating polymer networks (IPNs) composed of poly-.epsilon.-capolactone(PCL) and PEG macromer were syntheswized with the aim of obtaining a bioerodible hydrogel that could be used to release drugs for implantable delivery system. Polymerization of PEG macromer resulted in the formation of cross-linked gels due to the multifunctionality of macromer. Non-crosslinked PCL chains were interpenetrated into the cross-linked three-dimensions networks of PEG. The IPNs, largw drug loading lower concentration of PEG macromer in the IPNs concentration and the higher molecular weight of PEG macromer. Also, 5-FU was more fast released than hydrocortisone to the increased water solubility.

• Proceedings of the KOSOMBE Conference
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• v.1996 no.11
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• pp.327-330
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• 1996

Poly(L-leucine)(PLL)/poly(ethylene oxide)(PEO)/poly (L-leucine)(PLL) block copolymers were synthsized by polymerization of L-leucine N-carboxyanhydride with diamine-terminated PEO for possibility of wound dressing which may have several advantages such as 1) increase of solubility, 2) control of biodegradation, 3) absorption of body fluid. 4) non-immunogenic effect than PLL homopolymer wound dressing aleady commercialized. Water content increased with an increase of PEO content in the block copolymer due to the hydrophilicity of PEO. Release of silver sulfadiazine(AgSD) from AgSD loaded wound dressing increased with an increase of PEO content in the block copolymer. It was found that the number of Pseudomonas aeruginosa decrease with an increase of PEO content due to the fast release of antibacterial agents with an increase of PEO content in the block copolymer.

• Nuclear Engineering and Technology
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• v.37 no.1
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• pp.101-108
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• 2005

The neutron induced nuclear cross-section data for Pd-105, Ag-109, Xe-131, and Cs-133 were calculated and evaluated from an unresolved energy to 20 MeV. The energy dependent optical model potential parameters were extracted based on recent experimental data and applied up to 20 MeV. A spherical optical model and a statistical model for the equilibrium energy, and a multistep direct and a multistep compound model for the pre-equilibrium energy were used in the calculation. The direct capture model was recently introduced for fast neutron capture. The theoretically calculated cross-sections were compared with the experimental data and the evaluated files. The total and capture cross-sections calculated using the model were in good agreement with the reference experimental data. The evaluated cross-section results were compiled in ENDF-6 format and merged with the resonance component, already adopted in the ENDF/B-VI release 8. New data library files covering from thermal to 20 MeV were created. They are at the preliminary stage of an ENDF/B- VII release.

• Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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• 1991.10a
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• pp.53-58
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• 1991

This paper presents the speed control of DC motor based on deadbeat response method. Since 송 deadbeat response systems are characterized by the discrete time control, the instabiliby of the systems caused by saturation and time lag problems is inevitable. In order to release these problems, we propose a compensator utilizing the predictive control so that the fast response can be also achieved in the saturation state. Experimental results demonstrated that outputs are able to settle final values in on sampling time for unsaturated reference inputs. For saturated reference inputs, outputs take one sampling time after getting free from the saturation state. Further we are able to settle the fast response with suppressed overshoot by appling the predictive control.

• Proceedings of the Korean Information Science Society Conference
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• 2007.10d
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• pp.261-266
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• 2007

UMTS release 5 에서 소개된 HSDPA 를 위해 도입된 새로운 기술 Adaptive Modulation and Coding, Hybrid Automatic Repeal reQuest, Fast Packet Scheduling 에 대해 알아보고 여기서 key role 이 되는 Fast Packet Scheduling 알고리즘 가운데 대표적인 세 가지 Round Robin(RR), Promotional Fairness(PF), Maximum Channel Quality Index(Max CQI) 알고리즘의 성능을 시스템 수율과 공평성의 관점에서 분석해보았다. 시스템 수율에서는 Max CQI, PF. RR 알고리즘 순이었으며 공평성 측면에서는 RR, PF Max CQI 알고리즘 순으로 나타났다. 같은 시스템, 같은 망 구조 내에서라면 알고리즘을 최적화하여 QoS와 성능을 극대화할 수 있도록 지속적인 연구가 필요하다.

• Proceedings of the Korea Society for Simulation Conference
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• 1999.04a
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• pp.60-64
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• 1999

Recently in manufacturing environment, manufacturing order is characterized by unstable market demand, shorter product life cycle, a variety of product and shorter production lead time. In order to adapt this manufacturing order, flexible manufacturing system(FMS) in manufacturing technology advances into the direction that machines become further versatile functionally and that tools are controlled by fast tool delivery device. Unlike conventional FMS to mainly focus on part flow, it is important to control tool flow in single-stage multimachine systems(SSMS), consisting of versatile machines and fast tool delivery device. In this paper, in SSMS under dynamic tool allocation strategy to share tools among machines, we propose real-time part release and tool allocation algorithms which can apply real factory and which can improve system performance.

• Asian Journal of Turfgrass Science
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• v.22 no.1
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• pp.65-74
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• 2008

Traffic management is becoming an important issue in turfgrass practise on golf course. The objective of this study was to investigate the combined impact of different traffic times and types of fertilization. Traffic treatment was applied in morning (AM), noon, and afternoon (PM). Fertilizers used include faster-release fertilizer (21-17-17) and slow-release fertilizers (12-6-18, 11-3-22, 20-3-20, 10-3-10). Experiment was conducted from Oct. 1 to Nov. 30, 2005 on a nursery putting green of Incheon Grand Golf Club. The growth and quality of creeping bentgrass (Agrostis polustris cv. 'Seaside II') were evaluated on visual leaf color, leaf texture, shoot density, and root length. The measurement at 20 days after treatment, turfgrass color and leaf texture showed the best result on 10-15-10 + Noon-traffic plot. Turf quality and traffic tolerance were not different at Am and Pm traffic treatment. However, traffic stress in early morning and late evening caused the most severe damage to the turfgrass. Shoot density was the highest in 10-15-10 + Noon-traffic treatment but root length was not different among treatments after 30 day measurement. Among the fertilizers, slow release fertilizer resulted in higher turf quality and traffic tolerance than fast release fertilizer, however, shoot density did not showed a significantly different. For the fast recuperation of turfgrass from traffic injury in the early winter, it is recommended to avoid early morning and late evening traffic such as cup replacement and other maintenance practise. It is also recommended to delay the first tee-up time and ending early for last tee time during cold weather season.

• Journal of Photoscience
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• v.10 no.1
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• pp.37-48
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• 2003

A review of the background and development of the p-hydroxyphenacyl group (pHP) as a photoprotecting group for biological substrates is chronicled. The pHP group has promise as an efficient, rapid phototrigger for the study of very fast biological processes. Applications include the release of neurotransmittors and second messengers, enzyme switches and nucleotides.