• Proceedings of the Korea Contents Association Conference
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• 2005.05a
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• pp.36-50
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• 2005

e-Learning has been mushrooming with wide range of learning groups from pedagogy to andragogy. Despite of increasing e-learning opportunities, many people doubt whether e-learning learners really learn something. The related research papers emphasized that e-Learning would be a failure in terms of understanding of e-learners and intuitive learning activities for activating learner's long-term memory span. The current learning strategies in e-Learning may be based on the traditional classroom, and this results in boring and ineffective learning outcomes. This paper analyzed that how learners have received e-Learning for the last few years from the research and explained what could be the failing aspects of e-Learning. To be successful, e-Learning should consider the e-Learner's individualized teaming style and thinking patterns. When considering of various e-Learning components, the quality of e-learning should not be focused on any specific single factor, but develop every individual factor to the high level of quality. In conclusion, this paper suggest that we need new understand of e-Learning and e-Learner. Also the e-Learning strategies should be examined throughly whether they are on the side of learners and realized how they learn from e-Learning. Finally, we should add enormous imagination into e-Learning for next generation because their teaming patterns significantly differ from their parent's generation.

• The Journal of the Korea Contents Association
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• v.5 no.5
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• pp.316-324
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• 2005

e-Learning has been mushrooming with wide range of teaming groups from pedagogy to andragogy As e-teaming opportunities increase, many people raise question about whether e-teaming show positive teaming effects. The related research emphasized that e-learning would be a failure in terms of understanding of e-Learners and activating intuitive teaming activities from learner's long-term memory span. The e-teaming strategies based on the traditional classroom and resulted boring and ineffective teaming outcomes, should be changed to provide authentic and effective teaming results. This paper analyzed that how learners have received e-Learning for the last few years from the research and explained what could be the failing aspects in e-Learning. To be successful, e-loaming should consider the e-learner's individualized teaming style and thinking patterns. When considering of various e-Learning components, the quality of e-teaming should not be focused on any specific single factor, but develop every individual factor to be integrated into high level of quality. In conclusion, this paper suggest that it is needed new understandings of e-Loaming and e-Learner. Also the e-Learning strategies should be examined throughly whether they are on the side of learners and realized how they learn from e-Learning. Finally, we should add enormous imagination into e-loaming for next generation because new generation's teaming patterns significantly differ from their parent's generation.

• Journal of the Korean School Mathematics Society
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• v.14 no.3
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• pp.277-293
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• 2011

The purpose of mathematics education is to develop the ability of transforming various problems in general situations into mathematics problems and then solving the problem mathematically. Various teaching-learning methods for improving the ability of the mathematics problem-solving can be tried. However, it is necessary to choose an appropriate teaching-learning method after figuring out students' level of understanding the mathematics learning or their problem-solving strategies. The error analysis is helpful for mathematics learning by providing teachers more efficient teaching strategies and by letting students know the cause of failure and then find a correct way. The following subjects were set up and analyzed. First, the error classification pattern was set up. Second, the errors in the solving process of the function problems were analyzed according to the error classification pattern. For this study, the survey was conducted to 90 first grade students of ${\bigcirc}{\bigcirc}$high school in Chung-nam. They were asked to solve 8 problems in the function part. The following error classification patterns were set up by referring to the preceding studies about the error and the error patterns shown in the survey. (1)Misused Data, (2)Misinterpreted Language, (3)Logically Invalid Inference, (4)Distorted Theorem or Definition, (5)Unverified Solution, (6)Technical Errors, (7)Discontinuance of solving process The results of the analysis of errors due to the above error classification pattern were given below First, students don't understand the concept of the function completely. Even if they do, they lack in the application ability. Second, students make many mistakes when they interpret the mathematics problem into different types of languages such as equations, signals, graphs, and figures. Third, students misuse or ignore the data given in the problem. Fourth, students often give up or never try the solving process. The research on the error analysis should be done further because it provides the useful information for the teaching-learning process.

• Journal of the Korea institute for structural maintenance and inspection
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• v.21 no.4
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• pp.1-12
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• 2017

This paper concerns the structural behavior of high-strength concrete beams with compressive strength of 80 MPa subjected to flexure. Main test variables were nominal yielding strength of longitudinal rebar including normal strength rebar(SD 400) and high strength rebar(SD 600), reinforcement ratio from 0.98 to 1.58% and beam section size with $200{\times}250$, $200{\times}300mm$. The nine beams were cast and tested under flexure. The study investigated ultimate flexural strength, load-deflection relationship, crack patterns, failure patterns and ductility of the test beams. Test results indicate that when rebar ratio increased flexural strength increased and ductility decreased. In addition, the number of cracks increased and the crack width decreased as the reinforcement ratio increased. The yield strength of rebar did not affect significantly load-crack width relationship. Nonlinear analysis of test beams was performed and then test results and analytical results of ultimate load were compared. Analytical results of high-strength concrete beams overall underestimated flexural strength of test beams.

• Radiation Oncology Journal
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• v.37 no.3
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• pp.224-231
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• 2019

Purpose: To investigate the patterns of recurrence in patients with neuroblastoma treated with radiation therapy to the primary tumor site. Materials and Methods: We retrospectively analyzed patients with high-risk neuroblastoma managed with definitive treatment with radiation therapy to the primary tumor site between January 2003 and June 2017. These patients underwent three-dimensional conformal radiation therapy or intensity-modulated radiation therapy. A total of 14-36 Gy was delivered to the planning target volume, which included the primary tumor bed and the selected metastatic site. The disease stage was determined according to the International Neuroblastoma Staging System (INSS). We evaluated the recurrence pattern (i.e., local or systemic), progression-free survival, and overall survival. Results: A total of 40 patients with high-risk neuroblastoma were included in this study. The median patient age was 4 years (range, 1 to 11 years). Thirty patients (75%) had INSS stage 4 neuroblastoma. At the median follow-up of 58 months, there were 6 cases of local recurrence and 10 cases of systemic recurrence. Among the 6 local failure cases, 4 relapsed adjacent to the radiation field. The other 2 relapsed in the radiation field (i.e., para-aortic and retroperitoneal areas). The main sites of distant metastasis were the bone, lymph nodes, and bone marrow. The 5-year progression-free survival was 70.9% and the 5-year overall survival was 74.3%. Conclusion: Radiation therapy directed at the primary tumor site provides good local control. It seems to be adequate for disease control in patients with high-risk neuroblastoma after chemotherapy and surgical resection.

• Journal of Microbiology and Biotechnology
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• v.17 no.12
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• pp.2005-2017
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• 2007

Diabetic nephropathy remains a major cause of morbidity and mortality in the diabetic population and is the leading cause of end-stage renal failure. Despite current therapeutics including intensified glycemic control and blood pressure lowering agents, renal disease continues to progress relentlessly in diabetic patients, albeit at a lower rate. Since synthetic drugs for diabetes are known to have side effects, fungal mushrooms as a natural product come into preventing the development of diabetes. Our previous report showed the hypoglycemic effect of extracellular fungal polysaccharides (EPS) in streptozotocin (STZ)-induced diabetic rats. In this study, we analyzed the differential expression patterns of rat kidney proteins from normal, STZ-induced diabetic, and EPS-treated diabetic rats, to discover diabetes-associated proteins in rat kidney. The results of proteomic analysis revealed that up to 500 protein spots were visualized, of which 291 spots were differentially expressed in the three experimental groups. Eventually, 51 spots were statistically significant and were identified by peptide mass fingerprinting. Among the differentially expressed renal proteins, 10 were increased and 16 were decreased significantly in diabetic rat kidney. The levels of different proteins, altered after diabetes induction, were returned to approximately those of the healthy rats by EPS treatment. A histopathological examination showed that EPS administration restored the impaired kidney to almost normal architecture. The study of protein expression in the normal and diabetic kidney tissues enabled us to find several diabetic nephropathy-specific proteins, such as phospholipids scramblase 3 and tropomyosin 3, which have not been mentioned yet in connection with diabetes.

• Structural Engineering and Mechanics
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• v.47 no.4
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• pp.575-598
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• 2013

The study presents the results of an experimental program concerning the shear force transfer between reinforced concrete (RC) jackets and existing columns with damages. In order to investigate the effectiveness of the repair method applied and the contribution of each shear transfer mechanism of the interface. It includes 22 concrete columns (core) (of 24,37MPa concrete strength) with square section (150mm side, 500 mm height and scale 1:2). Ten columns had initial construction damages and twelve were subjected to initial axial load. Sixteen columns have full jacketing at all four faces with 80mm thickness (of 31,7MPa concrete strength) and contain longitudinal bars (of 500MPa nominal strength) and closed stirrups spaced at 25mm, 50mm or 100mm (of 220MPa nominal strength). Fourteen of them contain dowels at the interface between old and new concrete. All columns were subjected to repeated (pseudo-seismic) axial compression with increasing deformation cycles up to failure with or without jacketing. Two load patterns were selected to examine the difference of the behavior of columns. The effects of the initial damages, of the reinforcement of the interface (dowels) and of the confinement generated by the stirrups are investigated through axial- deformation (slip) diagrams and the energy absorbed diagrams. The results indicate that the initial damages affect the total behavior of the column and the capacity of the interface to shear mechanisms and to slip: a) the maximum bearing load of old column is decreased affecting at the same time the loading capacity of the jacketed element, b) suitable repair of initially damaged specimens increases the capacity of the jacketed column to transfer load through the interface.

• Journal of the Earthquake Engineering Society of Korea
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• v.8 no.5 s.39
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• pp.1-14
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• 2004

The seismic behavior of a 1/3-scale model of a two-story unreinforced masonry (URM) structure typically used in constructing low-rise residential buildings in Korea is studied through a shaking table test. The purposes of this study are to investigate seismic behavior and damage patterns of the URM structure that was not engineered against seismic loading and to provide its experimental test results. The test structure was symmetric about the transverse axis but asymmetric to some degrees about longitudinal axis and had a relatively strong diaphragm of concrete slab. The test structure was subjected to a series of differentlevels of earthquake shakings that were applied along the longitudinal direction. The measured dynamic response of the test structure was analyzed in terms of various global parameters (i.e., floor accelerations, base shear, floor displacements and storydrift, and torsional displacements) and correlated with the input table motion. Moreover, different levels of seismic performance were suggested for performance-based design approach. The results of the shaking table test revealed that the shear failure was dominant on a weak side of the 1stfloor while the upper part of the test model remained as a rigid body. Also, it was found that substantial strength and deformation capacity existed after cracking.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.19
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• pp.8259-8263
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• 2014

Aims: To determine the clinical characteristics, pathological features, local and distant failure patterns in patients with carcinoma of major salivary glands treated with surgery and postoperative radiotherapy (PORT). Materials and Methods: We retrospectively reviewed 106 cases of major salivary gland tumor seen at our centre (1998-2008). Sixty five cases of major salivary gland carcinoma were selected for analysis (exclusions: benign, palliative, non-carcinomas). The patient population treated by surgery and PORT was divided into two groups: 1) Patients who underwent surgery and immediate PORT (Primary PORT); 2) Patients with recurrent carcinoma who underwent at least two surgeries and received PORT in the immediate post-operative period of the last performed surgery (Recurrent PORT). Recurrence free survival (RFS) was assessed using the Kaplan-Meier method. Results: Median age was 35 years with a male: female ratio of 1.3:1. The majority of cancers were located in the parotid gland (86.2%) and the most common histology was mucoepidermoid carcinoma (43%). Thirty nine cases (60%) were primary while 26 (40%) were recurrent. Optimal surgery was performed in 59/65 patients (90.8%). 43 patients (66.2%) underwent neck dissection, of which 14 (32.5%) had nodal metastasis. Overall, 61 (93.8%) patients complied with the prescribed radiotherapy. Median dose of PORT was 60 Gy. Median follow-up was 13.1 months (range 2-70). Relapse free survival was 50.4% at 60 months. Some 12 cases (18.5%) recurred with a median time to recurrence of 16.9 months. Conclusions: Surgery and PORT is an effective treatment for major salivary gland carcinoma with over 90% compliance and <20% recurrence. Early treatment with postoperative radiotherapy may increase the survival rate in major salivary gland carcinoma patients.

• Journal of the Korea Concrete Institute
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• v.27 no.5
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• pp.471-480
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• 2015

The building structure is planned to maximize the use of space in recent. It was developed of a hybrid OCB (Optimized Composite Beam) for trying to take advantage of the maximize space. The OCB is composed of the steel h-beam section reinforced by open strands in negative moment zone and the psc concrete section in positive zone. Flexural behaviors of typical architectural bybrid OCB section was investigated. The 15 m OCB specimen was tested under three point static loading system. Following results are obtained from the tests; 1) The OCB with 15 m span develop initial flexural crackings under the 171% of full service loading. 2) Overall deflections of OCB under the service loads are less than those of the allowable limit in KCI Code provision. 3) The crack patterns, failure mode and ultimate load capacity of test specimen and F.E. model in this paper and they are compared to each other. The OCB is verified of structural reliability from the experimental results.