• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.9
• /
• pp.3645-3651
• /
• 2015

Background: Previous studies evaluating the association between the xeroderma pigmentosum group G (XPG) Asp1104His polymorphism and head and neck cancer susceptibility have proven controversial. This meta-analysis of the literature was performed to obtain a more precise estimation of the relationship. Materials and Methods: We systematically searched PubMed, Embase and Web of Science with a time limit of Dec 18, 2014. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the strength of any association. Results: We performed a meta-analysis of eight published case-control studies, including 3,621 cases and 5,475 controls. Overall, no significant association was found between the XPG Asp1104His polymorphism and head and neck cancer susceptibility under all genetic models. In the subgroup analysis by ethnicity, the XPG Asp1104His polymorphism had statistically significant association with elevated head and neck cancer risk under CC vs GG (OR=1.24, 95% CI=1.00~1.54) and the recessive model (OR=1.22, 95%CI=1.01~1.46) in Asian populations. A similar result was found under CC vs GG (OR =1.22, 95%CI=1.01~1.47) in the population based subgroup by source of control. When performed by tumor site, the XPG Asp1104His polymorphism had statistically significant association with elevated laryngeal cancer under all genetic models (CC vs GG: OR=1.59, 95% CI=1.16~2.19; GC vs GG: OR=1.38, 95%CI=1.10~1.72; dominant model: OR=1.42, 95% CI=1.15~1.74; recessive model: OR=1.36, 95% CI=1.02~1.81). Conclusions: This meta-analysis suggested that the XPG Asp1104His polymorphism is a risk factor for head and neck cancer susceptibility, especially for laryngeal cancer and in Asian populations.

• The Journal of the Acoustical Society of Korea
• /
• v.16 no.5
• /
• pp.112-121
• /
• 1997

In this paper, we study a model parameter compensation method for noise-robust speech recognition. We study model parameter compensation on a sentence by sentence and no other informations are used. Parallel model combination(PMC), well known as a model parameter compensation algorithm, is implemented and used for a reference of performance comparision. We also propose a modified PMC method which tunes model parameter with an association factor that controls average variability of gaussian mixtures and variability of single gaussian mixture per state for more robust modeling. We obtain a re-estimation solution of environmental variables based on the expectation-maximization(EM) algorithm in the cepstral domain. To evaluate the performance of the model compensation methods, we perform experiments on speaker-independent isolated word recognition. Noise sources used are white gaussian and driving car noise. To get corrupted speech we added noise to clean speech at various signal-to-noise ratio(SNR). We use noise mean and variance modeled by 3 frame noise data. Experimental result of the VTS approach is superior to other methods. The scheme of the zero order VTS approach is similar to the modified PMC method in adapting mean vector only. But, the recognition rate of the Zero order VTS approach is higher than PMC and modified PMC method based on log-normal approximation.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.22 no.3
• /
• pp.191-201
• /
• 2010

The breakwaters are designed by considering the cost optimization because a human risk is seldom considered. Most breakwaters, however, were constructed without considering the cost optimization. In this study, the optimum return period, target failure probability and the partial safety factors were evaluated by applying the cost optimization to the rubble mound breakwaters in Korea. The applied method was developed by Hans F. Burcharth and John D. Sorensen in relation to the PIANC Working Group 47. The optimum return period was determined as 50 years in many cases and was found as 100 years in the case of high real interest rate. Target failure probability was suggested by using the probabilities of failure corresponding to the optimum return period and those of reliability analysis of existing structures. The final target failure probability is about 60% for the initial limit state of the national design standard and then the overall safety factor is calculated as 1.09. It is required that the nominal diameter and weight of armor are respectively 9% and 30% larger than those of the existing design method. Moreover, partial safety factors considering the cost optimization were compared with those calculated by Level 2 analysis and a fairly good agreement was found between the two methods especially the failure probability less than 40%.

• Korean Journal of Environmental Biology
• /
• v.28 no.1
• /
• pp.30-39
• /
• 2010

We researched community structure, species composition, and habitat environment of Dendropanax morbifera populations distributed in Goheung, Haenam, Wando (I.), and Bogildo (I.) at south coast of the Korean Peninsula. Our research was also estimated possible area for growth of Dendropanax morbifera by analyzing meteorological factors of the habitat thereof. Dendropanax morbifera community divided into Castanopsis cuspidata var. sieboldii group and Carpinus laxiflora group by difference of species composition. Broad-leaved evergreens showed high dominance value in view of rNCD in Dendropanax morbifera community as follows: Camellia japonica (100.0), Quercus acuta (88.6), Castanopsis cuspidata var. sieboldii (55.8), Dendropanax morbifera Lev. (41.4), Trachelospermum asiaticum var. intermedium (23.8), Eurya japonica (19.9) and Ligustrum japonicum (11.5). In the population distribution, 94.2% of Carpinus laxiflora group consisted of sapling and small size class that are less than 5 cm in DBH while 54.2% of Castanopsis cuspidata var. sieboldii group did. The soil environment of habitat showed low soil acidity, good organic matter and water content, and good drainage. The distribution area of Dendropanax morifera habitat had $13^{\circ}C$ or more in annual mean temperature, $7.4^{\circ}C$ or more in daily minimum temperature, $100^{\circ}C$ month or more in warmth index, and approximately 1,344 mm in mean annual precipitation. Dendropanax morifera habitat corresponded to evergreen broad-leaved forest zone located in islands and coast in the southwest region of the Korean Peninsula. The northern limit line of Dendropanax morifera community was determined as Gunsan-Jeongeup-Gwangju-Jinju-Pohang-Youngdeok line based on $13^{\circ}C$ in annual mean temperature that was confirmed in natural habitat of Dendropanax morifera community.

• Tunnel and Underground Space
• /
• v.30 no.5
• /
• pp.473-483
• /
• 2020

This paper examines the vertical stress change concentrated on mine pillar which occurs due to the stress disturbance from opening excavation at room and pillar mine by FLAC3D, a finite difference method (FDM) software. The mesh size combination is decided with a careful consideration of relative error and run-time, then its performance is verified. A series of numerical analyses is conducted and the vertical stress at central pillar was observed for the test cases of 1×1 to 11×11 mine pillars, 40 m to 320 m depth with 40 m difference. The results show that the vertical stress of pillar approaches to the similar value with the value estimated by tributary area theory(TAT) when the development area (N_P) is increased or the height of overburden (H_OB) is decreased, while it is overestimated in the opposite case. Furthermore, it also represents that the vertical stress factor (VSF) converges to a specific value when the depth is increased whille keeping the development area identical.

• Proceedings of the KSRS Conference
• /
• 2008.10a
• /
• pp.220-223
• /
• 2008

A camera system for the satellite application performs the mission of observation by measuring radiated light energy from the target on the earth. As a development stage of the system, the signal level analysis by estimating the number of electron collected in a pixel of an applied CCD is a basic tool for the performance analysis like SNR as well as the data path design of focal plane electronic. In this paper, two methods are presented for the calculation of the number of electrons for signal level analysis. One method is a quantitative assessment based on the CCD characteristics and design parameters of optical module of the system itself in which optical module works for concentrating the light energy onto the focal plane where CCD is located to convert light energy into electrical signal. The other method compares the design\ parameters of the system such as quantum efficiency, focal length and the aperture size of the optics in comparison with existing camera system in orbit. By this way, relative count of electrons to the existing camera system is estimated. The number of electrons, as signal level of the camera system, calculated by described methods is used to design input circuits of AD converter for interfacing the image signal coming from the CCD module in the focal plane electronics. This number is also used for the analysis of the signal level of the CCD output which is critical parameter to design data path between CCD and A/D converter. The FPE(Focal Plane Electronics) designer should decide whether the dividing-circuit is necessary or not between them from the analysis. If it is necessary, the optimized dividing factor of the level should be implemented. This paper describes the analysis of the electron count of a camera system for a satellite application and then of the signal level for the interface design between CCD and A/D converter using two methods. One is a quantitative assessment based on the design parameters of the camera system, the other method compares the design parameters in comparison with those of the existing camera system in orbit for relative counting of the electrons and the signal level estimation. Chapter 2 describes the radiometry of the camera system of a satellite application to show equations for electron counting, Chapter 3 describes a camera system briefly to explain the data flow of imagery information from CCD and Chapter 4 explains the two methods for the analysis of the number of electrons and the signal level. Then conclusion is made in chapter 5.

• Journal of the Korean GEO-environmental Society
• /
• v.15 no.4
• /
• pp.43-51
• /
• 2014

A Large-diameter drilled shaft of deep water depth composite foundation supporting a high rise pylon of the test designed super long span bridge was designed by allowable stress design method and failure probability through reliability analysis to bearing capacity was estimated. The allowable stress design results for the bearing capacity of a drilled shaft were analyzed by reliability analysis and the probability of failure shows 0.12 % in case of CFEM, 0.0002 % in case of Korea Highway Corporation criterion, and 0.003 % in case of structure foundation design criterion. In the allowable stress design, the bearing capacity of a large-diameter drilled shaft was obtained by applying to safety factor 3 and reliability analysis for the results was done. If the failure probability suggested by AASHTO(2007) specification is set to 0.02 %, the socketed length of a drilled shaft shows an increase of 25 % in CFEM, decrease of 60 % in KHCC, and decrease of 89 % in SFDC.

• Asian-Australasian Journal of Animal Sciences
• /
• v.17 no.11
• /
• pp.1541-1552
• /
• 2004

The effect of eight varieties of whole crop rice silage (WCRS) harvested at four stages of maturity were investigated for in situ DM and N degradability, ME and MP yield and content in an 8${\times}$4 factorial experiment. The varieties were Akichikara, Fukuhibiki, Habataki, Hamasari, Hokuriku 168, Kusanami, Tamakei 96 and Yumetoiro. Hamasari and Kusanami were forage varieties while all others were grain varieties. Forages were harvested on 10, 22, 34 and 45 days after flowering, ensiled and kept in airtight condition. Between 45 and 49 days after ensiling, silages opened, chopped and milled green to pass through 4 mm screen. Samples were incubated in the rumen of two Holstein steers for 0, 3, 6, 9, 12, 24, 48, 72 and 96 h over eight 4 d periods. Bags at 0 h were washed in a washing machine. Variety affected DM (p<0.001: except 'a+b', p<0.01) and N (p<0.001) degradability characteristics of WCRS. Stages of maturity also affected DM (p<0.001: except 'a+b', p<0.05; 'c', p<0.08) and N (p<0.01: except 'c', p<0.05) degradability characteristics of WCRS. Interactions between variety and stages of maturity occurred in all DM (p<0.001) and N (p<0.001) degradability characteristics except (p>0.05) for DM 'b', DM 'c', DM 'a+b' nd N 'c'. Effective DM degradability was higher in grain varieties than forage varieties and degradability increased with maturity. N availability decreased only slightly with maturity. Variety was the key factor for N degradability characteristics of WCRS since variety accounted for most of the total variation for degradability characteristics. Both ME and MP content and yield were higher (p<0.001) in grain varieties, and they increased (p<0.001) with the maturity. The results clearly demonstrated that the grain type varieties contained higher ME and MP content than forage varieties, and increase in maturity increases both ME and MP content of WCRS.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.36 no.2
• /
• pp.307-315
• /
• 2016

Many countries are trying to reduce a greenhouse gas to step up their fight against climate change. There are many studies related to building only for reducing a greenhouse gas in construction area but studies related to reducing a comprehensive environmental load including various pollutants that affects the global environment are lacking. This study aims to analyse the characteristics of environmental load by work type for tunnel projects. Analysis showed that seven work types, including lining concrete, shotcrete, tunnel portal and open-cut tunnel work, etc., are representative works generated environmental load. These seven works represent 89.22 percent of total environmental load. In addition, comparison results of environmental load per tunnel's length by work type showed that a major factor of environmental load is caused by a tunnel portal and open-cut tunnel work with relatively short length (excavation length). And lining concrete and shotcrete work are larger than any other environmental load with tunnel's total length. It is expected that the result of this study will be used to make a estimation model for environmental load using approximate quantity survey of representative work types in the early stage of tunnel design. And it will be play a considerable role in establishing of environment management plan for sustainable infrastructure construction.

• Progress in Medical Physics
• /
• v.16 no.2
• /
• pp.53-61
• /
• 2005

The quality factors for cylindrical ionization chambers for kV X-rays were determined by Monte Carlo calculation and measurement. In this study, the X-rays of 60-300 kV beam (lSO-4037) installed in KFDA and specified in energy spectra and beam qualities, and the chambers of PTW N23333 and N30001 were investigated. In calculations, the $R_{\mu}\;and\;R_{Q,Q_{0}}$ in IAEA dosimetry protocols were determined from the air kerma and the cavity dose obtained by theoretical and Monte Carlo calculations. It is shown that the N30001 chamber has a flat response of $\pm1.7\%$ in $110\~300kV$ region, while the response range of two chambers were shown to $\pm3\~4\%$ in $80\~250kV$ region. From this work we have discussed dosimetry protocol for the kV X-rays and we have found that the estimation of energy dependency is more important to apply dosimetry protocol for kV X-rays.