• 제목/요약/키워드: factor base

검색결과 1,234건 처리시간 0.023초

Roles of Transcription Factor Binding Sites in the D-raf Promoter Region

  • Kwon, Eun-Jeong;Kim, Hyeong-In;Kim, In-Ju
    • Animal cells and systems
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    • 제2권1호
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    • pp.117-122
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    • 1998
  • D-raf, a Drosophila homolog of the human c-raf-1, is known as a signal transducer in cell proliferation and differentiation. A previous study found that the D-raf gene expression is regulated by the DNA replication-related element (DRE)/DRE-binding factor (DREF) system. In this study, we found the sequences homologous to transcription factor C/EBP, MyoD, STAT and Myc recognition sites in the D-raf promoter. We have generated various base substitutional mutations in these recognition sites and subsequently examined their effects on D-raf promoter activity through transient CAT assays in Kc cells with reporter plasmids p5'-878DrafCAT carrying the mutations in these binding sites. Through gel mobility shift assay using nuclear extracts of Kc cells, we detected factors binding to these recognition sites. Our results show that transcription factor C/EBP, STAT and Myc binding sites in D-raf promoter region play a positive role in transcriptional regulation of the D-raf gene and the Myo D binding site plays a negative role.

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은평구 장기전세주택 입주민의 주거만족도에 관한 연구 (Analysis of the residential satisfaction of SHift)

  • 허용;홍형옥;이현정
    • 한국주거학회:학술대회논문집
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    • 한국주거학회 2011년도 춘계학술발표대회 논문집
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    • pp.256-260
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    • 2011
  • In 2007, Seoul Metropolitan Government introduced new public rental housing policy called SHift that works as rental deposit base. The purpose of this study is to evaluate the residential satisfaction of SHift. This research has shown conclusively that there is a link between the Location of apartment, Internal Premises, External Premises and satisfaction of SHift residents. The main factors of Residential satisfaction of SHift residents are Location of economical factor. The factor analysis of the 12 factors of variable are confirmed by the internal consistency reliability. This analysis is evaluate on discrimination of the correlation between the dwelling circumstance and the residential satisfaction. The economical factor was the main factor among the Independent variables. It can be concluded that the general overview of the Residential Satisfaction of SHift residents satisfaction is "quite good". But there are maby problems on SHift.

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수학적 모델을 기반으로 한 단상 SRM의 고역률 저토크리플 구동방식 (High Power Factor Low Torque Ripple Drive Scheme of Single-Phase SRM based on Mathematical Model)

  • 양가녕;김태형;이동희;안진우
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2007년도 춘계학술대회 논문집 전기기기 및 에너지변환시스템부문
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    • pp.103-106
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    • 2007
  • This paper presents single-phase SRM drive system with single-stage high power factor and low torque ripple. Single-phase SRM has simple mechanical and electrical structure, robust and high speed operation characteristic. But conventional SRM drive with diode bridge rectifier and filter capacitor has a low power factor because of short charge time of capacitor. Therefore, this paper presents a novel single-phase SRM drive with single-stage structure circuit, which can improve the power factor and reduce peak torque ripple. A novel switching topology is presented base on mathematical analysis. The novel drive method is verified by simulations and experiments.

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피삭제와 공구재종의 상관관계에 근거한 절삭조건의 최적화(II) (Optmization of Cutting Condition based on the Relationship between Tool Grade and Workpiece Material (2nd. Report))

  • 한동원;고성림
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 1995년도 추계학술대회 논문집
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    • pp.169-172
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    • 1995
  • In optmizing cutting condition for face milling operation, tool wear is an important maching factor. For the purpose of establishing the relationship between various maching factor and tool wear, cutting tests have been performed. As a result, hardness and chemical composition of workpiece material, chemical compositition and grain size of cutting tool and cutting speed have been selected as machining factor. In addition, relationship between feed rate and workpiece hardness has been observed. Prior to utilizing cutting condition recommended by 'Machining Data Hardbook(MDH)' as a Knowledge base, an analysis for the validity has been provided. Based on this analysis, tool life criteria applied by MDH has been modifiied. Finaly, using MDH recommended data for neural network trainning, we can compensate the result form the trained neural network for optimizing cutting condition for some given workpice and cutting tool.

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성인남자 목부위의 연령별 형태변화에 관한 연구(제3보) -직접계측치와 주성분 분석에 의한 해석- (Observation on Neck Form Changes Related to Aging in Men (Part III) -by the Somatometric Data and the Principal Component Ana]isis-)

  • 이영숙
    • 한국의류학회지
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    • 제19권3호
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    • pp.463-470
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    • 1995
  • Anthropological measurements concerning 29 items were made on 37 adult males aged from 20 to 60. Factor analysis was applied in all 36 items. The main results are as gallows 1. Neck girth and need base girth are smaller. in the elder croup than the gouger group. 2. These decrease occur in the frontal part of the neck. 3. Neck frontal width decreases with age, but side depth increases. 4. The back part of the body depth at the level of the shoulder increases with age. 5. For the factor analysis, the third factor is a factor of forms, the variations of which has a relation with age.

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Strength reduction factor for multistory building-soil systems

  • Nik, Farhad Abedi;Khoshnoudian, Faramarz
    • Earthquakes and Structures
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    • 제6권3호
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    • pp.301-316
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    • 2014
  • This paper is devoted to investigate the effects of SSI on strength reduction factor of multistory buildings. A new formula is proposed to estimate strength reduction factors for MDOF structure-soil systems. It is concluded that SSI reduces the strength reduction factor of MDOF systems. The amount of this reduction is relevant to the fundamental period of structure, soil flexibility, aspect ratio and ductility of structure, and could be significantly different from corresponding fixed-base value. Using this formula, measuring the amount of this error could be done with acceptable accuracy. For some practical cases, the error attains up to 50%.

반도체산업에서의 인적오류제어방법 및 연구 (A method and analysis of human-error management of a semiconductor industry)

  • 윤용구;박범
    • 대한안전경영과학회지
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    • 제8권1호
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    • pp.17-26
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    • 2006
  • Basis frame-work's base in a semiconductor industry have gas, chemical, electricity and various facilities in bring to it. That it is a foundation by fire, power failure, blast, spill of toxicant huge by large size accident human and physical loss and damage because it can bring this efficient, connect with each kind mechanical, physical thing to prevent usefully need that control finding achievement factor of human factor of human action. Large size accident in a semiconductor industry to machine and human and it is involved that present, in system by safety interlock defect of machine is conclusion for error of behaviour. What is not construing in this study, do safety in a semiconductor industry to do improvement. Control human error analyzes in human control with and considers mechanical element and several elements. Also, apply achievement factor using O'conner Model by control method of human error. In analyze by failure mode effect using actuality example.

루버휜 최적 설계 및 최적 모델의 열유동 특성 분석 (Louvered Fin Heat Exchanger : Optimal Design and Numerical Investigation of Heat and Flow Characteristics)

  • 유기정;이관수
    • 설비공학논문집
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    • 제25권12호
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    • pp.654-659
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    • 2013
  • This paper presents a numerical optimization of louvered fins to enhance the JF factor in terms of the design parameters, including the fin pitch, the number of louvers, the louver angle, the fin thickness, and the re-direction louver length. We carried out a parametric study to select the three most important parameters affecting the JF factor, which were the fin pitch, number of louvers, and the louver angle. We optimally designed the louvered fin by using 3rd-order full factorial design, the kriging method, and a micro genetic algorithm. Consequently, the JF factor of the optimum model increased by 16% compared to that of the base model. Moreover, the optimum model reduced the pressure drop by 17% with a comparable heat transfer rate.

A Novel Weighting Factor Method in NLOS Environment

  • Guan, Xufeng;Hur, SooJun;Choi, JeongHee
    • 대한임베디드공학회논문지
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    • 제6권2호
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    • pp.108-116
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    • 2011
  • Non-line-of-sight (NLOS) error is the most common and also a major source of errors in wireless location system. A novel weighting factor (NWF) method is presented in this paper, based on the RSS(Received Signal Strength) measurements, path loss model and Circular Disk of Scatterers Model (CDSM). The proposed positioning method effectively weighted the TOA distance measurements for each Base Station (BS). Simulation results show that the proposed method efficiently weighted the distance measurements and achieve higher localization accuracy than that of Linear Line of Position (LLOP) and Believable Factor Algorithm (BFA).

폐특이 전사조절 유전자의 DNAse 1 Hypersensitive Sites (DNAse 1 Hypersensitive Sites of Lung Specific Transcription Factor Gene)

  • 이용철
    • Tuberculosis and Respiratory Diseases
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    • 제48권6호
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    • pp.879-886
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    • 2000
  • 연구배경: 폐특이 전사조절 유전자인 Thyroid Transcription Factor-1 (TTF-1)유전자는 폐에 선택적인 유전자의 표현의 조절에 중요한 전사인자로 작용하고 폐의 발생에서 morphogenic protein으로서 작용한다. 그러나 현재까지 이 TTF-1 유전자의 전사인자에 대한 연구는 거의 미미하다. DNase 1 hypersensitive(DH) regions은 활동적인 염색체에 대한 중요한 표식자이며 유전자를 조절하는 많은 DNA sequences와 밀접한 관계가 있다. 방법 : 추정적인 distal regulatory elements를 밝혀 내기 위해서 TTF-1을 표현하는 인간의 폐선암 세포주인 NCI-H441을 사용해 DNase 1 hypersensitive site assay를 이용하였다. 결과 : TTF-1 유전자에는 전사의 시작부위에서 +150, -450, -800, 그리고 -1500 base pair부위에 4곳의 DH sites가 있음을 할 수 있었다. 결론 : 이상의 결과로 전사 조절부위가 TTF-1 유전자 내에 그리고 5' prime부위에 위치함을 추정할 수 있었다.

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