• 제목/요약/키워드: factor 5'

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생쥐 배아의 전사와 발생에서 DNA/RNA 메틸화의 역할

  • 김종월
    • 한국발생생물학회:학술대회논문집
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    • 한국발생생물학회 1998년도 제4차 학술발표대회 및 정기총회
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    • pp.32-33
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    • 1998
  • 생물체에서 유전외적 변형의 하나인 DNA 메틸화는 cis-acting factor의 조성변화를 통하여 세포특이 유전자의 발현과 virus latency, genomic imprinting, mutagenesis등과 같은 생물학적 효과를 나타내는 것으로 알려져 있다.(reviewed by Olle Heby, 1995). 5-azaCR, 5-azaCdR 그리고 6-azaCR의 처리결과는 배아자체의 DNA 메틸화의 유지가 정상발생에 필수적임을 알 수 있으며, 메틸화에 의한 배아발생 조절기작이 존재함을 암시하고 있다. 이러한 과정에서 5-azaCR과 5-azaCdR은 서로다른 경로를 통하여 배아발생에 관여함을 보여주었다. 즉, 5-azaCdR은 주로 DNA에 incorporation되어 작용하는 것으로 여겨지며, 5-azaCR은 DNA 보다는 RNA에 incorporation되어 작용하는 것으로 나타났다. 그리고, 비록 소수의 유전자만이 조사되었지만, 5-azaCdR의 incorporation에 의한 cis-acting factor의 변화는 전사인자인 c-myc proto-oncogene과 fluid 수송에 관여하는 $Na^{+}$, $K^{+}$-ATPase 유전자의 전사를 억제하지 않았다. 반면, 5-azaCR의 RNA로의 incorporation은 전사인자인 c-myc proto-oncogene의 전사를 억제하였으며, 연이어 fluid 수송에 관련되어있는 $Na^{+}$, $K^{+}$-ATPase 유전자의 전사를 억제하였다. 이것은 아마도 RNA로 incorporation된 5-azaCR은 RNA의 post-transcriptional processing에 영향을 주어 trans-acting factor의 조성을 변화, 전사적 repression을 유발한 것으로 사료된다. 생쥐 착상전 초기배아에서 DNA 메틸화는 short-term하게는 cis-acting factor로써 전사적 수준에서 유전자발현 조절하며, 그리고 유전자발현을 통하여 long-term하게는 배아발생에 관여 할 것이라고 사료된다.

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5083-0 알루미늄合金의 疲勞균열進展 擧動과 균열닫힘에 관한 硏究 (A study of Fatigue Crack Growth Behavior and Crack Closure in 5083-O Aluminum Alloy)

  • 박영조;김정규;김일현
    • 대한기계학회논문집
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    • 제10권2호
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    • pp.208-214
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    • 1986
  • 본 연구에서는 균열 닫힘에 관한 연구의 일환으로 5083-O 알루미늄합금을 사용하고 소규모강복조건하에서 일정진폭하중피로시험을 시행하여 이 재료의 피로균열 진전속도와 균열닫힘에 관하여 검토하였다.

중국 성인 여성의 체형 연구(I) -북경과 상해에 거주하는 여성을 중심으로- (A Study on the Body Types of the Chinese Women (I) -Focusing on Beijing and Shanghai-)

  • 임순;손희순;석혜정
    • 한국의류학회지
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    • 제27권7호
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    • pp.831-842
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    • 2003
  • The purpose of this study is to analyze body types of Chinese women and provide concrete information on it by classifying them into several representative groups. As for the method of this study, statistical analysis is made of 79 items. This is done from July 18 to Aug 07, 2002, 525 female subjects from age 20 to 49 participated in this study. They all live in Beijing and Shanghai in China. The results of this study are as follows. 1. Means, standard deviations, the maximum and minimum of 19 items are extracted. The height and girth item have a high standard deviations. 2. 8 factors are extracted by using factor analysis. Factor 1: body obesity, Factor 2: vertical body size, Factor 3: upper body length Factor 4: size of ankles, Factor 5: angle of shoulders, Factor 6: length of hip Factor 7: size of shoulder, Factor 8: shape of chest 3. The body types of Chinese women are classified into 5 sub groups from the result of the Cluster analysis.

A Study on the Structural Causal Relationship of Marketing Stimulating Factors on Online Impulse Purchase through Consumer Value: Focusing on the Mediating Effect of Consumer Value

  • KWON, Lee-Seung;LEE, Jae-Min
    • 웰빙융합연구
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    • 제5권3호
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    • pp.7-17
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    • 2022
  • Purpose: With the introduction of Web 2.0, the advent of smartphones, and the recent outbreak of COVID-19 worldwide, interest in online shopping has soared. In an online shopping environment, the desire for impulse buying increases compared to offline shopping. Research design, data and methodology: In this study, three marketing stimulating factors such as product factor, price factor, and facilitating factor were selected which affect impulse buying for clothing and accessory products in the Korean online shopping environment. The mechanism of causal relationship among them, and the role customer value between marketing stimulating factor and impulse buying was analyzed. Results: The analysis results are as follows. First, the product factor had a significant positive effect on consumer value and impulse buying. Second, the price factor also had a significant positive effect on consumer value and impulse buying. Conclusions: Although the facilitating factor had no significant influence on consumer value and impulse buying, the indirect effect through consumer value was positively significant. Consumer value had a positive mediating effect on impulse purchase in the order of price factor, product factor, and promotion factor.

도펀트 첨가에 따른 0.57Pb(Sc1/2Nb1/2)O3-0.43PbTiO3 세라믹스의 유전 및 압전특성 (Dielectric and Piezoelectric Properties of 0.57Pb(Sc1/2Nb1/2)O3-0.43PbTiO3 Ceramics with Dopant Additions)

  • 지승한;권상직
    • 한국전기전자재료학회논문지
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    • 제20권2호
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    • pp.124-129
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    • 2007
  • Dielectric and piezoelectric properties of $0.57Pb(Sc_{1/2}Nb_{1/2})O_{3}-0.43PbTiO_{3}$, which is the morphotropic phase boundary composition for the PSN-PT system, were investigated as a function of $Fe_{2}O_{3},\;Nb_{2}O_{5}\;and\;MnO_{2}$ addition 0 wt% to 0.9 wt%. The maximum dielectric constant of ${\varepsilon}_{33}/{\varepsilon}_{o}=2054$ and the minimum dielectric loss of $tan{\delta}=0.37\;%$ at room temperature were obtained at 0.1 wt% of $Fe_{2}O_{3}$ and 0.5 wt% of $MnO_{2}$ addition, respectively. With addition of 0.5 wt% $Nb_{2}O_{5}$ and $0.5\;wt%\;MnO_{2}$, the electromechanical coupling factor $k_{p}$ and mecanical quality factor $Q_{m}$ were significantly increased, respectively. The maximum electromechanical coupling factor $k_{p}=61.5\;%$ was obtained by addition of $Nb_{2}O_{5}$ and high mechanical quality factor $Q_{m}=919$ was obtained by addition of $MnO_{2}$. The $Q_{m}(=919)$ value is 3.3 times larger than that of non-doped 0.57PSN-0.43PT ceramics.

TEOS-$H_2O$계로부터 다공성 실리카 막의 제조 및 수소-질소 혼합기체의 분리 (Preparation of Microporous Silica Membrane from TEOS-$H_2O$ System and Separation Of $H_2$-$N_2$ Gas Mixture)

  • 강태범;이현경;이용택
    • 멤브레인
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    • 제10권2호
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    • pp.55-65
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    • 2000
  • 다공성 실리카 막을 졸겔법에 의해서 Si(${OC}_2H_5)_4-H_2O$ 로부터 제조하고, 막의 특성을 TG-DTA, XRD, IR, BET, SEN, TEM을 사용하여 조사하였다. 다공성 실리카 막 제조를 위한 Si(${OC}_2H_5)_4$ : $H_2O4$ : $H_2O$ : $C_2H_5{OH}$의 최적 몰비는 1 : 4.5 : 4 이었다. 100$^{\circ}C$~1100$^{\circ}C$~에서 열처리된 막의 비표면적은 3.8 $m^2$/g~902.3$m^2$/g 이었으며, 기공크기는 20$\AA$~50$\AA$이었다. 300$^{\circ}C$~~700$^{\circ}C$~범위에서 열처리된 막의 입자크기는 15nm~30nm이며, 열처리 온도가 증가하면 입자의 크기도 증가하였다. 이렇게 제조한 다공성 실리카 막으로 $H_2$/$N_2$ 혼합기체를 분리하는데 응용하였으며, 다공성 실리카 막에 의한 $H_2$/$N_2$혼합기체분리는 Knudsen flow와 surface flow에 의해서 일어나며 주로 surface flow에 의존하였다. 다공성 실리카 막의 $H_2$/$N_2$ 혼합기체에 대한 real separation factor($\alpha$)는 155.15 cmHg($\Delta$P)와 $25^{\circ}C$에서 5.17이었으며, real separation factor($\alpha$), head separation factor ($\beta$), tail separation factor$\bar{B}$)는 압력이 증가하면 증가하였다.

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LOCALLY SEMICOMPLETE DIGRAPHS WITH A FACTOR COMPOSED OF k CYCLES

  • Gould, Ronald J.;Guo, Yubao
    • 대한수학회지
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    • 제41권5호
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    • pp.895-912
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    • 2004
  • A digraph is locally semicomplete if for every vertex $\chi$, the set of in-neighbors as well as the set of out-neighbors of $\chi$ induce semicomplete digraphs. Let D be a k-connected locally semicomplete digraph with k $\geq$ 3 and g denote the length of a longest induced cycle of D. It is shown that if D has at least 7(k-1)g vertices, then D has a factor composed of k cycles; furthermore, if D is semicomplete and with at least 5k + 1 vertices, then D has a factor composed of k cycles and one of the cycles is of length at most 5. Our results generalize those of [3] for tournaments to locally semicomplete digraphs.

전공식 콘트롤 밸브 Positioner 용 Magnet Unit의 해석 (An Analysis of Magnet Unit of Electro-Pneumtic Control Valve Positioner)

  • 김성재;김지원;조순철;정선태;유형근;전찬구;고택범
    • 한국자기학회지
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    • 제7권6호
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    • pp.321-326
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    • 1997
  • 유량을 정밀조정하는 콘트롤 밸브의 핵심 부품인 magnet unit를 해석하였다. 유한요소법을 이용하여 자석과 요크가 이루는 자기회로를 분석하여 공극에 흐르는 자속과 코일이 받는 힘을 계산하고 이를 측정치와 비교하였다. 시뮬레이션 결과 공극자장은 3 ~ 5 kOe, 추력상수는 27.5 N/A, 퍼미언스 게수는 22.1 이었으며 측정치와 잘 일치하였다. 또한 시뮬레이션을 통하여 reluctance factor는 1.1 fringing factor는 1.4 임을 알 수 있었다.

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일체형 보강판의 균열성장거동(I)-SIF의 수치해석 (Crack growth behavior in the lntegrally stiffened plates(1) -Numerical evaluation of SIF)

  • 이환우
    • 한국정밀공학회지
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    • 제14권5호
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    • pp.150-156
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    • 1997
  • Three dimensional finite element analysis was conducted to estimate the effect of shape parameters (plate width and thickness) on the stress intensity factor for crack in the integrally stiffened plate. Analysis was done for width ratios of 0.5, 0.75, 1.0, 1.5, 2.0, 2.5, and thickness ratios of 2, 3, 4, 6. Based on these results, an empirical equation of geometry factor is formulated as a function of crack length and thickness ratio.

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PSN-PMN-PZT 세라믹스의 Zr/Ti 비에 따른 전기적 특성과 공진주파수의 온도안정성 (Electrical Properties and Temperature Stability of resonant Frequency with Zr/Ti ratio in PSN-PMN-PZT Ceramics)

  • 류주현;윤광희;민석규;이명수;서성재
    • 한국전기전자재료학회논문지
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    • 제13권8호
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    • pp.675-680
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    • 2000
  • In this study the temperature coefficient of resonant frequency(TC $F_{r}$) dielectric and piezoelectric properties of Pb[(S $b_{1}$2//N $b_{1}$2/)$_{0.065}$)-(Z $r_{x}$, $Ti_{1-x}$ )$_{0.90}$] $O_3$ceramics were investigated with Zr/Ti ratio. The compositions near the morphotropic phase boundary (MPB) appeared when Zr/Ti ratio was 49.5/50.5 The dielectric constant and electromechanical coupling factor( $k_{p}$) also showed the highest values of 1,257, 0.653 respectively when the Zr/Ti ratio was 49.5/50.5 Moreover the mechanical quality factor( $Q_{m}$) showed th lowest value of 713 when the Zr/Ti ratio. The temperature coefficient of resonant frequency(TC $F_{r}$) abruptly change at the morphotropic phase boundary(MPB) which existed between the rhombohedral phase with highly negative TC $F_{r}$ of -106ppm/$^{\circ}C$ and the tetragonal phase with highly positive TC $F_{r}$ of +64pp $m^{\circ}C$ as Zr/Ti ratio varied from 50/50 to 49.5/50.5.50.5..50.5.

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